Role of lipopolysaccharide-binding protein in early alcohol-induced liver injury in mice

Journal of Immunology

Volumn 168, Issue 6, 2002, Pages 2963-2969

  Uesugi, Takehiko ^a   Froh, Matthias ^a   Arteel, Gavin E ^a   Bradford, Blair U ^a   Wheeler, Michael D ^a   Gäbele, Erwin ^a   Isayama, Fuyumi ^a   Thurman, Ronald G ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; CYTOCHROME P450 2E1; CYTOKINE; DEXTRIN; ENDOTOXIN; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE BINDING PROTEIN; MALTOSE; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FATTY LIVER; IMMUNE RESPONSE; KNOCKOUT MOUSE; KUPFFER CELL; LIVER INJURY; LIVER NECROSIS; LIVER TOXICITY; MOUSE; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; SCORING SYSTEM; SIGNAL TRANSDUCTION; WEIGHT GAIN;

EID: 0037087374     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.6.2963     Document Type: Article

References (46)

1. Gram-negative endotoxin: An extraordinary lipid with profound effects on eukaryotic signal transduction
2. Pathogenesis and potential strategies for prevention and treatment of septic shock: An update
3. Lipopolysaccharide binding protein expression in primary human hepatocytes and HepG2 hepatoma cells
4. Monoclonal antibodies to murine lipopolysaccharide (LPS)-binding protein (LBP) protect mice from lethal endotoxemia by blocking either the binding of LPS to LBP or the presentation of LPS/LBP complexes to CD14
5. Plasma lipopolysaccharide (LPS)-binding protein: A key component in macrophage recognition of Gram-negative LPS
6. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
7. Structure and function of lipopolysaccharide binding protein
8. Kupffer cell activation by lipopolysaccharide in rats: Role for lipopolysaccharide binding protein and tolllike receptor 4
9. Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS
10. 2
11. The leaky gut of alcoholism: Possible route of entry for toxic compounds
12. Antibiotics prevent liver injury in rats following long-term exposure to ethanol
13. Essential role of tumor necrosis factor a in alcohol induced liver injury
14. Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin
15. Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver disease
16. Reduced early alcohol-induced liver injury in cd14-deficient mice
17. Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice
18. Longterm cannulation model for blood sampling and intragastric infusion in the rat
19. Effects of ethanol ingestion and dietary fat levels on mitochondrial lipids in male and female rats
20. Fish oil, alcohol, and liver pathology: Role of cytochrome P4502El
21. Intragastric ethanol infusion model for cellular and molecular studies of alcoholic liver disease
22. Episodic excretion of ethanol during chronic intragastric ethanol infusion in the male rat: Continuous vs. cyclic ethanol and nutrient infusions
23. Female rats exhibit greater susceptibility to early alcoholinduced injury than males
24. Chromogenic endotoxin assay in plasma: Selection of plasma pretreatment and production of standard curves
25. Clottable protein in Limulus: Its localization and kinetics of its coagulation by endotoxin
26. Beef fat prevents alcoholic liver disease in the rat
27. Identification and induction of cytochromes P450, P450IIE1 and P4501A1 in rabbit bone marrow
28. Cyclical pattern of blood alcohol levels during continuous intragastric ethanol infusion in rats
29. Mechanism of the alcohol cyclic pattern: Role of the hypothalamic-pituitary-thyroid axis
30. Early alcoholic liver injury: Formation of protein adducts with acetaldehyde and lipid peroxidation products, and expression of CYP2E1 and CYP3A
31. Jejunal microflora in patients with chronic alcohol abuse
32. Apoptosis and dysregulated ceramide metabolism in a murine model of alcohol-enhanced lipopolysaccharide hepatotoxicity
33. Exacerbation of alcoholic liver injury by enteral endotoxin in rats
34. CD14 and lipopolysaccharide binding protein expression in a rat model of alcoholic liver disease
35. Targeted deletion of the lipopolysaccharide (LPS)-binding protein gene leads to profound suppression of LPS responses ex vivo, whereas in vivo responses remain intact
36. Lipopolysaccharide-binding protein as a major plasma protein responsible for endotoxemic shock
37. Lipopolysaccharide-binding protein is required to combat a murine Gram-negative bacterial infection
38. Lipoproteins inhibit macrophage activation by lipoteichoic acid
39. Mechanisms of hepatic toxicity. II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin
40. Effect of intravenous immunoglobulin G on the TNFα-mediated hepatic microvascular inflammatory response
41. Ethanol potentiates tumor necrosis factor-α cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition
42. Tumor necrosis factor-α stimulates hepatic lipogenesis in the rat in vivo
43. Stimulation of lipolysis in cultured fat cells by tumor necrosis factor, interleukin-1, and the interferons is blocked by inhibition of prostaglanding synthesis
44. Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids
45. ICAM-1 is involved in the mechanism of alcohol-induced liver injury: Studies with knockout mice