Apoptosis and human diseases: Mitochondrion damage and lethal role of released cytochrome c as proapoptotic protein

Current Medicinal Chemistry

Volumn 16, Issue 31, 2009, Pages 4058-4065

  Caroppi, P ^a   Sinibaldi, F ^a   Fiorucci, L ^a   Santucci, R ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Apoptosis; Cardiolipin; Cytochrome c; Mitochondria; Mitochondrial membrane

Indexed keywords

AMINO ACID DERIVATIVE; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 1 INHIBITOR; CASPASE 3 INHIBITOR; CASPASE INHIBITOR; CELL PROTEIN; CYTOCHROME C; MEMBRANE PROTEIN; MITOCHONDRIAL PROTEIN; PEROXIDASE; PROCASPASE 9; PROTEIN BCL 2; PROTEIN DERIVATIVE; PROTEINASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; APOPTOSIS; AUTOPHAGY; BRAIN ISCHEMIA; CARBOXY TERMINAL SEQUENCE; CARDIOVASCULAR DISEASE; CATALYSIS; CELL ACTIVATION; CELL CYCLE REGULATION; CELL GROWTH; CELL MEMBRANE DEPOLARIZATION; CELL ORGANELLE; CELL PERMEABILIZATION; CELL STRESS; CYTOSOL; DEGENERATIVE DISEASE; DISEASE COURSE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DISSOCIATION; DNA FRAGMENTATION; DRUG RESEARCH; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME REGULATION; GENERAL ASPECTS OF DISEASE; GROWTH REGULATION; HUMAN; MALIGNANT NEOPLASTIC DISEASE; MEMBRANE PERMEABILITY; MEMBRANE RUPTURE; MITOCHONDRIAL MEMBRANE; MOLECULAR DYNAMICS; NERVE CELL NECROSIS; NONHUMAN; OLIGOMERIZATION; OXIDATIVE STRESS; PATHOGENESIS; PEROXIDATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TARGETING; RESPIRATORY CHAIN; REVIEW; SIGNAL TRANSDUCTION;

APOPTOSIS; CARDIOVASCULAR DISEASES; CYTOCHROMES C; HUMANS; MITOCHONDRIA; NEOPLASMS; NEURODEGENERATIVE DISEASES;

EID: 70450205079     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986709789378206     Document Type: Review

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