From fat to inflammation

Gastroenterology

Volumn 130, Issue 1, 2006, Pages 207-210

  Day, Christopher Paul ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ADIPONECTIN; ANGIOTENSINOGEN; CATHEPSIN B; FATTY ACID; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LEPTIN; NORADRENALIN; OSTEOPONTIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

CARCINOGENESIS; CYTOKINE RELEASE; DISEASE ASSOCIATION; DISEASE COURSE; FATTY ACID OXIDATION; HEPATITIS; HUMAN; INSULIN RESISTANCE; KUPFFER CELL; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER FIBROSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

EID: 30044431801     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2005.11.017     Document Type: Article

References (23)

1. C.P. Day Natural history of NAFLD remarkably benign in the absence of cirrhosis Gastroenterology 129 2005 375 378
2. D. Cai, M. Yuan, D. Frantz, P.A. Melendez, L. Hansen, J. Lee, S.E. Shoelson Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κβ Nat Med 11 2005 183 190
3. M.C. Arkan, A.L. Hevener, F.R. Greten, S. Maeda, Z.-W. Li, J.M. Lond, A. Wynshaw-Boris, G. Poli, J. Olefsky, M. Karin IKK-β links inflammation to obesity- induced insulin resistance Nat Med 11 2005 191 198
4. V.T. Samuel, Z.-X. Liu, X. Qu, B.D. Elder, S. Bilz, D. Befroy, A.J. Romanelli, G.I. Shulman Mechanism of hepatic insulin resistance in non alcoholic fatty liver disease J Biol Chem 279 2004 32345 32353
5. K. Ueki, T. Kondo, Y.-H. Tseng, C.R. Kahn Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse Proc Natl Acad Sci U S A 101 2004 10422 10427
6. J. Crespo, A. Cayon, P. Fernandez-Gil, M. Hernandez-Guerra, M. Mayorga, A. Dominguez-Diez, J.C. Fernandez-Escalante, F. Pons-Romero Gene expression of tumour necrosis factor α and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients Hepatology 34 2001 1158 1163
7. Z. Li, M.J. Soloski, A.M. Diehl Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease Hepatology 42 2005 880 885
8. A.E. Feldstein, N.W. Werneburg, A. Canbay, M.E. Guicciardi, S.F. Bronk, R. Rydzewski, L.J. Burgart, G.J. Gores Free fatty acids promote hepatic lipotoxicity by stimulating TNF-α expression via a lysosomal pathway Hepatology 40 2004 185 194
9. S. Nielsen, Z. Guo, C.M. Johnson, D.D. Hensrud, M.D. Jensen Splanchnic lipolysis in human obesity J Clin Invest 113 2004 1582 1588
10. K.L. Donnelly, C.I. Smith, S.J. Schwarzenberg, J. Jessurun, M.D. Boldt, E.J. Parks Sources of fatty acids stored in liver and secreted via lipoproteins in patients with non alcoholic fatty liver disease J Clin Invest 115 2005 1343 1351
11. U. Ozcan, Q. Cao, E. Yilmaz, A.-H. Lee, N.N. Iwakoshi, E. Ozdelen, G. Tuncman, C. Gorgun, L.H. Glimcher, G.S. Hotamisligil Endoplasmic reticulum stress links obesity, insulin action and Type 2 diabetes Science 306; 2004 457 461
12. D. Ron Translational control in the endoplasmic reticulum stress response J Clin Invest 110 2002 1383 1388
13. 1ATZ in the ER activates caspases -4 and -12, NFκB and BAP31 but not the unfolded protein response J Biol Chem 280 2005 39002 39015
14. S.Q. Yang, H.Z. Lin, M.D. Lane, M. Clemens, A.M. Diehl Obesity increases sensitivity to endotoxin liver injury implications for the pathogenesis of steatohepatitis Proc Natl Acad Sci U S A 94 1997 2557 2562
15. S.P. Weisberg, D. McCann, M. Desai, M. Rosenbaum, R.L. Leibel, A.W. Ferrante Jr Obesity is associated with macrophage accumulation in adipose tissue J Clin Invest 112 2003 1796 1808
16. A. Sahai, P. Malladi, H. Melin-Aldana, R.M. Green, P.F. Whitington Upregulation of osteopontin expression is involved in the development of non alcoholic steatohepatitis in a dietary murine model Am J Physiol Gastrointest Liver Physiol 287 2004 264 273
17. N. Maeda, I. Shimomura, K. Kishida, H. Nishizawa, M. Matsuda, H. Nagaretani, N. Furuyama, H. Kondo, M. Takahashui, Y. Arita, R. Komuro, N. Ouchi, S. Kihara, Y. Tochino, K. Okutomi, M. Horie, S. Takeda, T. Aoyama, T. Funahashi, Y. Matsuzawa Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 Nat Med 8 2002 731 737
18. A. Xu, Y. Wang, H. Keshaw, L.Y. Xu, K.S. Lam, G.J. Cooper The fat-derived hormone adiponectin alleviates alcoholic and non alcoholic fatty liver disease in mice J Clin Invest 112 2003 91 100
19. J.M. Hui, A. Hodge, G.C. Farrell, J.G. Kench, A. Kriketos, J. George Beyond insulin resistance in NASH TNFα or adiponectin? Hepatology 40 2004 46 54
20. S. Kaser, A. Moschen, A. Cayon, A. Kaser, J. Crespo, F. Pons-Romero, C.F. Ebenbichler, J.R. Patsch, H. Tilg Adiponectin and its receptors in non-alcoholic steatohepatitis Gut 54 2005 117 121
21. E. Pikarsky, R.M. Porat, I. Stein, R. Abramovitch, S. Amit, S. Kasem, E. Gutkovich-Pyest, S. Urieli-Shoval, E. Galun, Y. Ben-Neriah NFκB functions as a tumor promoter in inflammation-associated cancer Nature 431 2004 461 465
22. R.S. Hundal Mechanism by which high dose aspirin improves glucose metabolism in type 2 diabetes J Clin Invest 109 2002 1321 1326
23. C.P. Day The potential role of genes in nonalcoholic fatty liver disease Clin Liver Dis 8 2004 673 691