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Volumn 175, Issue 11, 2005, Pages 7447-7456

Multiple TLRs are expressed in human cholangiocytes and mediate host epithelial defense responses to Cryptosporidium parvum via activation of NF-κB

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; MYELOID DIFFERENTIATION FACTOR 88; SMALL INTERFERING RNA; SYNAPTOPHYSIN; T LYMPHOCYTE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

EID: 28244478101     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.11.7447     Document Type: Article
Times cited : (190)

References (58)
  • 1
    • 0028919819 scopus 로고
    • Cryptosporidium and cryptosporidiosis in man and animals
    • O'Donoghue, P. J. 1995. Cryptosporidium and cryptosporidiosis in man and animals. Int. J. Parasitol 25: 139-195.
    • (1995) Int. J. Parasitol. , vol.25 , pp. 139-195
    • O'Donoghue, P.J.1
  • 3
    • 0030623684 scopus 로고    scopus 로고
    • Cryptosporidiosis: An emerging, highly infectious threat
    • Guerrant, R. L. 1997. Cryptosporidiosis: an emerging, highly infectious threat. Emerg. Infect. Dis. 3: 51-57.
    • (1997) Emerg. Infect. Dis. , vol.3 , pp. 51-57
    • Guerrant, R.L.1
  • 4
    • 0032111722 scopus 로고    scopus 로고
    • Hepatobiliary diseases in patients with AIDS: Focus on AIDS cholangiopathy and gallbladder disease
    • Wilcox, C. M., and K. E. Monkemuller. 1998. Hepatobiliary diseases in patients with AIDS: focus on AIDS cholangiopathy and gallbladder disease. Dig. Dis. 16: 205-213.
    • (1998) Dig. Dis. , vol.16 , pp. 205-213
    • Wilcox, C.M.1    Monkemuller, K.E.2
  • 6
    • 0032160062 scopus 로고    scopus 로고
    • Treatment for AIDS-associated Cryptosporidiosis
    • Griffiths, J. K. 1998. Treatment for AIDS-associated Cryptosporidiosis. J. Infect. Dis. 178: 915-916.
    • (1998) J. Infect. Dis. , vol.178 , pp. 915-916
    • Griffiths, J.K.1
  • 7
    • 0032823158 scopus 로고    scopus 로고
    • New insights into human Cryptosporidiosis
    • Clark, D. P. 1999, New insights into human Cryptosporidiosis. Clin. Microbiol. Rev. 12: 554-563.
    • (1999) Clin. Microbiol. Rev. , vol.12 , pp. 554-563
    • Clark, D.P.1
  • 9
    • 2442452473 scopus 로고    scopus 로고
    • Cryptosporidium parvum attachment to and internalization by human biliary epithelia in vitro: A morphologic study
    • Huang, B. Q., X. M. Chen, and N. F. LaRusso. 2004. Cryptosporidium parvum attachment to and internalization by human biliary epithelia in vitro: a morphologic study. J. Parasitol 90: 212-221.
    • (2004) J. Parasitol. , vol.90 , pp. 212-221
    • Huang, B.Q.1    Chen, X.M.2    LaRusso, N.F.3
  • 10
    • 0038054141 scopus 로고    scopus 로고
    • Cryptosporidium parvum invasion of biliary epithelia requires host cell tyrosine phosphorylation of cortactin via c-Src
    • Chen, X. M., B. Q. Huang, P. L. Splinter, H. Cao, G. Zhu, M. A, McNiven, and N. F. LaRusso. 2003. Cryptosporidium parvum invasion of biliary epithelia requires host cell tyrosine phosphorylation of cortactin via c-Src. Gastroenterology 125: 216-228.
    • (2003) Gastroenterology , vol.125 , pp. 216-228
    • Chen, X.M.1    Huang, B.Q.2    Splinter, P.L.3    Cao, H.4    Zhu, G.5    McNiven, M.A.6    LaRusso, N.F.7
  • 11
    • 1942504249 scopus 로고    scopus 로고
    • Host intestinal epithelial response to Crypsosporidium parvum
    • Deng, M., M, S. Rutherford, and M. S. Abrahamsen. 2004. Host intestinal epithelial response to Crypsosporidium parvum. Adv. Drug Delivery Rev. 56: 869-884.
    • (2004) Adv. Drug Delivery Rev. , vol.56 , pp. 869-884
    • Deng, M.1    Rutherford, M.S.2    Abrahamsen, M.S.3
  • 13
    • 0030831109 scopus 로고    scopus 로고
    • Cryptosporidium parvum infection of human intestinal epithelial cells induces the polarized secretion of C-X-C chemokines
    • Laurent, F., L. Eckmann, T. C. Savidge, G. Morgan, C. Theodos, M. Naciri, and M. F. Kagnoff. 1997. Cryptosporidium parvum infection of human intestinal epithelial cells induces the polarized secretion of C-X-C chemokines. Infect. Immun. 65: 5067-5073.
    • (1997) Infect. Immun. , vol.65 , pp. 5067-5073
    • Laurent, F.1    Eckmann, L.2    Savidge, T.C.3    Morgan, G.4    Theodos, C.5    Naciri, M.6    Kagnoff, M.F.7
  • 14
    • 2142653566 scopus 로고    scopus 로고
    • Differential regulation of β-defensin gene expression during Cryptosporidium parvum infection
    • Zaalouk, T. K., M. Bajaj-Elliott, J. T. George, and V. McDonald. 2004. Differential regulation of β-defensin gene expression during Cryptosporidium parvum infection. Infect. Immun. 72: 2772-2779.
    • (2004) Infect. Immun. , vol.72 , pp. 2772-2779
    • Zaalouk, T.K.1    Bajaj-Elliott, M.2    George, J.T.3    McDonald, V.4
  • 16
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira, S., and K. Takeda. 2004. Toll-like receptor signalling. Nat. Rev. Immunol. 4: 499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 17
    • 0141799911 scopus 로고    scopus 로고
    • Defensins: Antimicrobial peptides of innate immunity
    • Ganz, T. 2003. Defensins: antimicrobial peptides of innate immunity. Nat. Rev. Immunol. 3: 710-720.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 710-720
    • Ganz, T.1
  • 19
    • 0032734313 scopus 로고    scopus 로고
    • Expression and regulation of the human β-defensins hBD-1 and hBD-2 in intestinal epithelium
    • O'Neil, D. A., E. M. Porter, D. Elewaut, G. M. Anderson, L. Eckmann, T. Ganz, and M. F. Kagnoff. 1999. Expression and regulation of the human β-defensins hBD-1 and hBD-2 in intestinal epithelium. J. Immunol. 163: 6718-6724.
    • (1999) J. Immunol. , vol.163 , pp. 6718-6724
    • O'Neil, D.A.1    Porter, E.M.2    Elewaut, D.3    Anderson, G.M.4    Eckmann, L.5    Ganz, T.6    Kagnoff, M.F.7
  • 20
    • 0037446650 scopus 로고    scopus 로고
    • Modulation of human β-defensin-2 transcription in pulmonary epithelial cells by lipopolysaccharide-stimulated mononuclear phagocytes via proinflammatory cytokine production
    • Tsutsumi-Ishii, Y., and I. Nagaoka. 2003. Modulation of human β-defensin-2 transcription in pulmonary epithelial cells by lipopolysaccharide-stimulated mononuclear phagocytes via proinflammatory cytokine production. J. Immunol. 170: 4226-4236.
    • (2003) J. Immunol. , vol.170 , pp. 4226-4236
    • Tsutsumi-Ishii, Y.1    Nagaoka, I.2
  • 21
    • 0346366980 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human β defensin-2
    • Hertz, C. J., Q. Wu, E. M. Porter, Y. J. Zhang, K. H. Weismuller, P. J. Godowski, T. Ganz, S. H. Randell, and R. L. Modlin. 2003. Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human β defensin-2. J. Immunol. 171: 6820-6826.
    • (2003) J. Immunol. , vol.171 , pp. 6820-6826
    • Hertz, C.J.1    Wu, Q.2    Porter, E.M.3    Zhang, Y.J.4    Weismuller, K.H.5    Godowski, P.J.6    Ganz, T.7    Randell, S.H.8    Modlin, R.L.9
  • 23
    • 0033956581 scopus 로고    scopus 로고
    • Mechanisms of attachment and internalization of Cryptosporidium parvum to biliary and intestinal epithelial cells
    • Chen, X. M., and N. F. LaRusso. 2000. Mechanisms of attachment and internalization of Cryptosporidium parvum to biliary and intestinal epithelial cells. Gastroenterology 118: 368-379.
    • (2000) Gastroenterology , vol.118 , pp. 368-379
    • Chen, X.M.1    LaRusso, N.F.2
  • 25
    • 0029006149 scopus 로고
    • Inhibition of nuclear translocation of transcription factor NF-κB by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence
    • Lin, Y. Z., S. Y. Yao, R. A. Veach, T. R. Torgerson, and J. Hawiger. 1995. Inhibition of nuclear translocation of transcription factor NF-κB by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J. Biol. Chem. 270: 14255-14258.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14255-14258
    • Lin, Y.Z.1    Yao, S.Y.2    Veach, R.A.3    Torgerson, T.R.4    Hawiger, J.5
  • 26
    • 0034703072 scopus 로고    scopus 로고
    • CD14-dependent lipopolysaccharide-induced β-defensin-2 expression in human tracheobronchial epithelium
    • Becker, M. N., G. Diamond, M. W. Verghese, and S. H. Randell. 2000. CD14-dependent lipopolysaccharide-induced β-defensin-2 expression in human tracheobronchial epithelium. J. Biol. Chem. 275: 29731-29736.
    • (2000) J. Biol. Chem. , vol.275 , pp. 29731-29736
    • Becker, M.N.1    Diamond, G.2    Verghese, M.W.3    Randell, S.H.4
  • 28
    • 0037458570 scopus 로고    scopus 로고
    • Specific inhibition of AQP1 water channels in isolated rat intrahepatic bile duct units by small interfering RNAs
    • Splinter, P. L., A. I. Masyuk, and N. F. LaRusso. 2003. Specific inhibition of AQP1 water channels in isolated rat intrahepatic bile duct units by small interfering RNAs. J. Biol. Chem. 278: 6268-6274.
    • (2003) J. Biol. Chem. , vol.278 , pp. 6268-6274
    • Splinter, P.L.1    Masyuk, A.I.2    LaRusso, N.F.3
  • 29
    • 2142717379 scopus 로고    scopus 로고
    • Cdc42 and the actin-related protein/neural Wiskott-Aldrich syndrome protein network mediate cellular invasion by Cryptosporidium parvum
    • Chen, X. M., B. Q. Huang, P. L. Splinter, J. D. Orth, D. D. Billadeau, M. A. McNiven, and N. F. LaRusso. 2004, Cdc42 and the actin-related protein/neural Wiskott-Aldrich syndrome protein network mediate cellular invasion by Cryptosporidium parvum. Infect. Immun. 12: 3011-3021.
    • (2004) Infect. Immun. , vol.12 , pp. 3011-3021
    • Chen, X.M.1    Huang, B.Q.2    Splinter, P.L.3    Orth, J.D.4    Billadeau, D.D.5    McNiven, M.A.6    LaRusso, N.F.7
  • 30
    • 3843077534 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium porvum cellular invasion via activation of Cdc42
    • Chen, X. M., P. L. Splinter, P. S. Tietz, B. Q. Huang, D. D. Billadeau, and N. F. LaRusso. 2004. Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium porvum cellular invasion via activation of Cdc42. J. Biol. Chem. 279: 31671-31678.
    • (2004) J. Biol. Chem. , vol.279 , pp. 31671-31678
    • Chen, X.M.1    Splinter, P.L.2    Tietz, P.S.3    Huang, B.Q.4    Billadeau, D.D.5    LaRusso, N.F.6
  • 31
    • 1642494708 scopus 로고    scopus 로고
    • Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: Evidence for an intracellular compartmentalization of TLR4
    • Guillot, L., S. Medjane, K. Le-Barillec, V. Balloy, C. Danel, M. Chignard, and M. Si-Tahar. 2004. Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: evidence for an intracellular compartmentalization of TLR4. J. Biol Chem. 279: 2712-2718.
    • (2004) J. Biol. Chem. , vol.279 , pp. 2712-2718
    • Guillot, L.1    Medjane, S.2    Le-Barillec, K.3    Balloy, V.4    Danel, C.5    Chignard, M.6    Si-Tahar, M.7
  • 32
    • 0033009907 scopus 로고    scopus 로고
    • Regulation of interleukin-8 gene expression
    • Roebuck, K. A. 1999. Regulation of interleukin-8 gene expression. J. Interferon Cytokine Res. 19: 429-438.
    • (1999) J. Interferon Cytokine Res. , vol.19 , pp. 429-438
    • Roebuck, K.A.1
  • 33
    • 0037080024 scopus 로고    scopus 로고
    • Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
    • Zarember, K. A., and P. J. Godowski. 2002. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J. Immunol. 168: 554-561.
    • (2002) J. Immunol. , vol.168 , pp. 554-561
    • Zarember, K.A.1    Godowski, P.J.2
  • 34
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki, A., and R. Medzhitov. 2004, Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5: 987-995.
    • (2004) Nat. Immunol. , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 35
    • 0041743207 scopus 로고    scopus 로고
    • The Toll-like receptor repertoire of human B lymphocytes: Inducible and selective expression of TLR9 and TLR10 in normal and transformed cells
    • Bourke, E., D. Bosisio, J. Golay, N. Polentarutti, and A. Mantovani. 2003. The Toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells. Blood 102: 956-963.
    • (2003) Blood , vol.102 , pp. 956-963
    • Bourke, E.1    Bosisio, D.2    Golay, J.3    Polentarutti, N.4    Mantovani, A.5
  • 36
    • 0036570169 scopus 로고    scopus 로고
    • Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
    • Homung, V., S. Rothenfusser, S. Britsch, A. Krug, B. Jahrsdorfer, T. Giese, S. Endres, and G. Hartmann. 2002. Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J. Immunol. 168: 4531-4537.
    • (2002) J. Immunol. , vol.168 , pp. 4531-4537
    • Homung, V.1    Rothenfusser, S.2    Britsch, S.3    Krug, A.4    Jahrsdorfer, B.5    Giese, T.6    Endres, S.7    Hartmann, G.8
  • 37
    • 0034445697 scopus 로고    scopus 로고
    • Differential alteration in intestinal epithelial cell expression of Toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
    • Cario, E., and D. K. Podolsky. 2000. Differential alteration in intestinal epithelial cell expression of Toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect. Immun. 68: 7010-7017.
    • (2000) Infect. Immun. , vol.68 , pp. 7010-7017
    • Cario, E.1    Podolsky, D.K.2
  • 38
    • 0037307854 scopus 로고    scopus 로고
    • Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: Implications for host-microbial interactions in the gut
    • Melmed, G., L. S. Thomas, N. Lee, S. Y. Tesfay, K. Lukasek, K. S. Michelsen, Y. Zhou, B. Hu, M. Arditi, and M. T. Abreu. 2003. Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut. J. Immunol. 170: 1406-1415.
    • (2003) J. Immunol. , vol.170 , pp. 1406-1415
    • Melmed, G.1    Thomas, L.S.2    Lee, N.3    Tesfay, S.Y.4    Lukasek, K.5    Michelsen, K.S.6    Zhou, Y.7    Hu, B.8    Arditi, M.9    Abreu, M.T.10
  • 39
    • 0035881675 scopus 로고    scopus 로고
    • Cutting edge: Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
    • Gewirtz, A. T., T. A. Navas, S. Lyons, P. J. Godowski, and J. L. Madara. 2001. Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J. Immunol. 167: 1882-1885.
    • (2001) J. Immunol. , vol.167 , pp. 1882-1885
    • Gewirtz, A.T.1    Navas, T.A.2    Lyons, S.3    Godowski, P.J.4    Madara, J.L.5
  • 40
    • 7944231342 scopus 로고    scopus 로고
    • Does the microbiota regulate immune responses outside the gut?
    • Noverr, M. C., and G. B. Huffnagle. 2004. Does the microbiota regulate immune responses outside the gut? Trends Microbiol. 12: 562-568.
    • (2004) Trends Microbiol. , vol.12 , pp. 562-568
    • Noverr, M.C.1    Huffnagle, G.B.2
  • 41
    • 4644359523 scopus 로고    scopus 로고
    • Peptide antibiotic human β-defensin-1 and -2 contribute to antimicrobial defense of the intrahepatic biliary tree
    • Harada, K., K. Ohba, S. Ozaki, K. Isse, T. Hirayama, A. Wada, and Y. Nakanuma. 2004. Peptide antibiotic human β-defensin-1 and -2 contribute to antimicrobial defense of the intrahepatic biliary tree. Hepatology 40: 925-932.
    • (2004) Hepatology , vol.40 , pp. 925-932
    • Harada, K.1    Ohba, K.2    Ozaki, S.3    Isse, K.4    Hirayama, T.5    Wada, A.6    Nakanuma, Y.7
  • 42
    • 0242413703 scopus 로고    scopus 로고
    • Lipopolysaccharide activates nuclear factor-κB through Toll-like receptors and related molecules in cultured biliary epithelial cells
    • Harada, K., S. Ohira, K. Isse, S, Ozaki, Y. Zen, Y. Sato, and Y. Nakanuma. 2003. Lipopolysaccharide activates nuclear factor-κB through Toll-like receptors and related molecules in cultured biliary epithelial cells. Lab. Invest. 83: 1657-1667.
    • (2003) Lab. Invest. , vol.83 , pp. 1657-1667
    • Harada, K.1    Ohira, S.2    Isse, K.3    Ozaki, S.4    Zen, Y.5    Sato, Y.6    Nakanuma, Y.7
  • 45
    • 0842305635 scopus 로고    scopus 로고
    • Myd88-dependent in vivo maturation of splenic dendritic cells induced by Leishmania donovani and other Leishmania species
    • De Trez, C., M. Brait, O. Leo, T. Aebischer, F. A. Torrentera, Y. Carlier, and E. Muraille. 2004. Myd88-dependent in vivo maturation of splenic dendritic cells induced by Leishmania donovani and other Leishmania species. Infect. Immun. 72: 824-832.
    • (2004) Infect. Immun. , vol.72 , pp. 824-832
    • De Trez, C.1    Brait, M.2    Leo, O.3    Aebischer, T.4    Torrentera, F.A.5    Carlier, Y.6    Muraille, E.7
  • 46
    • 1642525756 scopus 로고    scopus 로고
    • Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88
    • Campos, M. A., M. Closel, E. P. Valente, J. E. Cardoso, S. Akira, J. I. Alvarez-Leite, C. Ropert, and R. T. Gazzinelli. 2004. Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88. J. Immunol. 172: 1711-1718.
    • (2004) J. Immunol. , vol.172 , pp. 1711-1718
    • Campos, M.A.1    Closel, M.2    Valente, E.P.3    Cardoso, J.E.4    Akira, S.5    Alvarez-Leite, J.I.6    Ropert, C.7    Gazzinelli, R.T.8
  • 47
    • 0032935615 scopus 로고    scopus 로고
    • A role for host phosphoinositide 3-kinase and cytoskeletal remodeling during Cryptosporidium parvum infection
    • Forney, J. R., D. B. DeWald, S. Yang, C. A. Speer, and M. C. Healey. 1999. A role for host phosphoinositide 3-kinase and cytoskeletal remodeling during Cryptosporidium parvum infection. Infect. Immun. 67: 844-852.
    • (1999) Infect. Immun. , vol.67 , pp. 844-852
    • Forney, J.R.1    DeWald, D.B.2    Yang, S.3    Speer, C.A.4    Healey, M.C.5
  • 48
    • 0034116189 scopus 로고    scopus 로고
    • Cryptosporidium parvum induces host cell actin accumulation at the host-parasite interface
    • Elliott, D. A., and D. P. Clark. 2000. Cryptosporidium parvum induces host cell actin accumulation at the host-parasite interface. Infect. Immun. 68: 2315-2322.
    • (2000) Infect. Immun. , vol.68 , pp. 2315-2322
    • Elliott, D.A.1    Clark, D.P.2
  • 51
    • 0041589276 scopus 로고    scopus 로고
    • Pneumocystis carinii cell wall β-glucans initiate macrophage inflammatory responses through NF-κB activation
    • Lebron, F., R. Vassallo, V. Puri, and A. H. Limper. 2003. Pneumocystis carinii cell wall β-glucans initiate macrophage inflammatory responses through NF-κB activation. J. Biol. Chem. 278: 25001-25008.
    • (2003) J. Biol. Chem. , vol.278 , pp. 25001-25008
    • Lebron, F.1    Vassallo, R.2    Puri, V.3    Limper, A.H.4
  • 52
    • 2342535902 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and Toll-like receptor 2 as well as Toll-like receptor 5
    • Adamo, R., S. Sokol, G. Soong, M. I. Gomez, and A. Prince. 2004. Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and Toll-like receptor 2 as well as Toll-like receptor 5. Am. J. Respir. Cell Mol. Biol. 30: 627-634.
    • (2004) Am. J. Respir. Cell Mol. Biol. , vol.30 , pp. 627-634
    • Adamo, R.1    Sokol, S.2    Soong, G.3    Gomez, M.I.4    Prince, A.5
  • 53
    • 1342344961 scopus 로고    scopus 로고
    • Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by Toll-like receptors
    • Kim, J. G., S. J. Lee, and M. F. Kagnoff. 2004. Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by Toll-like receptors. Infect. Immun. 72: 1487-1495.
    • (2004) Infect. Immun. , vol.72 , pp. 1487-1495
    • Kim, J.G.1    Lee, S.J.2    Kagnoff, M.F.3
  • 54
    • 22244465576 scopus 로고    scopus 로고
    • Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-κB activation in muramyl dipeptide recognition
    • Barnich, N., J. E. Aguirre, H. C. Reinecker, R. Xavier, and D. K. Podolsky. 2005. Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-κB activation in muramyl dipeptide recognition. J. Cell Biol. 170: 21-26.
    • (2005) J. Cell Biol. , vol.170 , pp. 21-26
    • Barnich, N.1    Aguirre, J.E.2    Reinecker, H.C.3    Xavier, R.4    Podolsky, D.K.5
  • 55
    • 0033580949 scopus 로고    scopus 로고
    • Peptidoglycan- and lipoteichotc acid-induced cell activation is mediated by Toll-like receptor 2
    • Schwandner, R., R, Dziarski, H. Wesche, M. Rothe, and C. J. Kirschning. 1999. Peptidoglycan- and lipoteichotc acid-induced cell activation is mediated by Toll-like receptor 2. J. Biol Chem. 274: 17406-17409.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17406-17409
    • Schwandner, R.1    Dziarski, R.2    Wesche, H.3    Rothe, M.4    Kirschning, C.J.5
  • 56
  • 57
    • 4344688669 scopus 로고    scopus 로고
    • IL-17 markedly up-regulates β-defensin-2 expression in human airway epithelium via JAK and NF-κB signaling pathways
    • Kao, C. Y., Y. Chen, P. Thai, S. Wachi, F. Huang, C. Kim, R. W. Harper, and R. Wu. 2004. IL-17 markedly up-regulates β-defensin-2 expression in human airway epithelium via JAK and NF-κB signaling pathways. J. Immunol. 173: 3482-3491.
    • (2004) J. Immunol. , vol.173 , pp. 3482-3491
    • Kao, C.Y.1    Chen, Y.2    Thai, P.3    Wachi, S.4    Huang, F.5    Kim, C.6    Harper, R.W.7    Wu, R.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.