메뉴 건너뛰기




Volumn 54, Issue 6, 2011, Pages 2185-2197

An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: Regulation of proinflammatory cytokines and hepatic steatosis in mice

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A OXIDASE; ALANINE AMINOTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE I; CD68 ANTIGEN; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CYTOKINE; DNA; ENDOTOXIN; FATTY ACID; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RANTES; RECOMBINANT CYTOKINE; RECOMBINANT MONOCYTE CHEMOTACTIC PROTEIN 1; TOLL LIKE RECEPTOR 4; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 82455167937     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24599     Document Type: Article
Times cited : (237)

References (40)
  • 1
    • 0141625009 scopus 로고    scopus 로고
    • Recent insights into the role of the innate immune system in the development of alcoholic liver disease
    • Nagy LE. Recent insights into the role of the innate immune system in the development of alcoholic liver disease. Exp Biol Med (Maywood) 2003; 228: 882-890.
    • (2003) Exp Biol Med (Maywood) , vol.228 , pp. 882-890
    • Nagy, L.E.1
  • 2
    • 67349255858 scopus 로고    scopus 로고
    • Signalling pathways in alcohol-induced liver inflammation
    • Mandrekar P, Szabo G. Signalling pathways in alcohol-induced liver inflammation. J Hepatol 2009; 50: 1258-1266.
    • (2009) J Hepatol , vol.50 , pp. 1258-1266
    • Mandrekar, P.1    Szabo, G.2
  • 4
    • 0031685777 scopus 로고    scopus 로고
    • Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis
    • Afford SC, Fisher NC, Neil DA, Fear J, Brun P, Hubscher SG, Adams DH. Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis. J Pathol 1998; 186: 82-89.
    • (1998) J Pathol , vol.186 , pp. 82-89
    • Afford, S.C.1    Fisher, N.C.2    Neil, D.A.3    Fear, J.4    Brun, P.5    Hubscher, S.G.6    Adams, D.H.7
  • 5
    • 0032795476 scopus 로고    scopus 로고
    • Serum concentrations and peripheral secretion of the beta chemokines monocyte chemoattractant protein 1 and macrophage inflammatory protein 1alpha in alcoholic liver disease
    • Fisher NC, Neil DA, Williams A, Adams DH. Serum concentrations and peripheral secretion of the beta chemokines monocyte chemoattractant protein 1 and macrophage inflammatory protein 1alpha in alcoholic liver disease. Gut 1999; 45: 416-420.
    • (1999) Gut , vol.45 , pp. 416-420
    • Fisher, N.C.1    Neil, D.A.2    Williams, A.3    Adams, D.H.4
  • 6
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm
    • Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1994; 76: 301-314.
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.A.1
  • 7
    • 0031040539 scopus 로고    scopus 로고
    • Chemokines: leucocyte recruitment and activation cytokines
    • Adams DH, Lloyd AR. Chemokines: leucocyte recruitment and activation cytokines. Lancet 1997; 349: 490-495.
    • (1997) Lancet , vol.349 , pp. 490-495
    • Adams, D.H.1    Lloyd, A.R.2
  • 8
    • 0034095445 scopus 로고    scopus 로고
    • Impact of alcohol on the ability of Kupffer cells to produce chemokines and its role in alcoholic liver disease
    • Bautista AP. Impact of alcohol on the ability of Kupffer cells to produce chemokines and its role in alcoholic liver disease. J Gastroenterol Hepatol 2000; 15: 349-356.
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. 349-356
    • Bautista, A.P.1
  • 9
    • 0032536531 scopus 로고    scopus 로고
    • Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice
    • Lu B, Rutledge BJ, Gu L, Fiorillo J, Lukacs NW, Kunkel SL, et al. Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J Exp Med 1998; 187: 601-608.
    • (1998) J Exp Med , vol.187 , pp. 601-608
    • Lu, B.1    Rutledge, B.J.2    Gu, L.3    Fiorillo, J.4    Lukacs, N.W.5    Kunkel, S.L.6
  • 10
    • 0026547872 scopus 로고
    • Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes
    • Jiang Y, Beller DI, Frendl G, Graves DT. Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes. J Immunol 1992; 148: 2423-2428.
    • (1992) J Immunol , vol.148 , pp. 2423-2428
    • Jiang, Y.1    Beller, D.I.2    Frendl, G.3    Graves, D.T.4
  • 11
    • 0036617747 scopus 로고    scopus 로고
    • Chronic alcohol intoxication primes Kupffer cells and endothelial cells for enhanced CC-chemokine production and concomitantly suppresses phagocytosis and chemotaxis
    • Bautista AP. Chronic alcohol intoxication primes Kupffer cells and endothelial cells for enhanced CC-chemokine production and concomitantly suppresses phagocytosis and chemotaxis. Front Biosci 2002; 7: a117-a125.
    • (2002) Front Biosci , vol.7
    • Bautista, A.P.1
  • 12
    • 33745216724 scopus 로고    scopus 로고
    • MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
    • Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, Kitazawa R, et al. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 2006; 116: 1494-1505.
    • (2006) J Clin Invest , vol.116 , pp. 1494-1505
    • Kanda, H.1    Tateya, S.2    Tamori, Y.3    Kotani, K.4    Hiasa, K.5    Kitazawa, R.6
  • 13
    • 51349151813 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 secreted by adipose tissue induces direct lipid accumulation in hepatocytes
    • Clement S, Juge-Aubry C, Sgroi A, Conzelmann S, Pazienza V, Pittet-Cuenod B, et al. Monocyte chemoattractant protein-1 secreted by adipose tissue induces direct lipid accumulation in hepatocytes. Hepatology 2008; 48: 799-807.
    • (2008) Hepatology , vol.48 , pp. 799-807
    • Clement, S.1    Juge-Aubry, C.2    Sgroi, A.3    Conzelmann, S.4    Pazienza, V.5    Pittet-Cuenod, B.6
  • 14
    • 34848914069 scopus 로고    scopus 로고
    • Signaling mechanisms in alcoholic liver injury: role of transcription factors, kinases and heat shock proteins
    • Mandrekar P. Signaling mechanisms in alcoholic liver injury: role of transcription factors, kinases and heat shock proteins. World J Gastroenterol 2007; 13: 4979-4985.
    • (2007) World J Gastroenterol , vol.13 , pp. 4979-4985
    • Mandrekar, P.1
  • 15
    • 70249091176 scopus 로고    scopus 로고
    • The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes
    • Mandrekar P, Bala S, Catalano D, Kodys K, Szabo G. The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. J Immunol 2009; 183: 1320-1327.
    • (2009) J Immunol , vol.183 , pp. 1320-1327
    • Mandrekar, P.1    Bala, S.2    Catalano, D.3    Kodys, K.4    Szabo, G.5
  • 16
    • 67649968443 scopus 로고    scopus 로고
    • Oxidative stress and alcoholic liver disease
    • Wu D, Cederbaum AI. Oxidative stress and alcoholic liver disease. Semin Liver Dis 2009; 29: 141-154.
    • (2009) Semin Liver Dis , vol.29 , pp. 141-154
    • Wu, D.1    Cederbaum, A.I.2
  • 17
  • 19
    • 47949094965 scopus 로고    scopus 로고
    • Integration of metabolism and inflammation by lipid-activated nuclear receptors
    • Bensinger SJ, Tontonoz P. Integration of metabolism and inflammation by lipid-activated nuclear receptors. Nature 2008; 454: 470-477.
    • (2008) Nature , vol.454 , pp. 470-477
    • Bensinger, S.J.1    Tontonoz, P.2
  • 21
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer SA, Umesono K, Noonan DJ, Heyman RA, Evans RM. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 1992; 358: 771-774.
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 23
    • 77951146612 scopus 로고    scopus 로고
    • C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis
    • Obstfeld AE, Sugaru E, Thearle M, Francisco AM, Gayet C, Ginsberg HN, et al. C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis. Diabetes 2010; 59: 916-925.
    • (2010) Diabetes , vol.59 , pp. 916-925
    • Obstfeld, A.E.1    Sugaru, E.2    Thearle, M.3    Francisco, A.M.4    Gayet, C.5    Ginsberg, H.N.6
  • 25
    • 0034015563 scopus 로고    scopus 로고
    • Ethanol potentiates tumor necrosis factor-alpha cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition
    • Pastorino JG, Hoek JB. Ethanol potentiates tumor necrosis factor-alpha cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition. Hepatology 2000; 31: 1141-1152.
    • (2000) Hepatology , vol.31 , pp. 1141-1152
    • Pastorino, J.G.1    Hoek, J.B.2
  • 26
    • 41349098793 scopus 로고    scopus 로고
    • Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury
    • Horiguchi N, Wang L, Mukhopadhyay P, Park O, Jeong WI, Lafdil F, et al. Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury. Gastroenterology 2008; 134: 1148-1158.
    • (2008) Gastroenterology , vol.134 , pp. 1148-1158
    • Horiguchi, N.1    Wang, L.2    Mukhopadhyay, P.3    Park, O.4    Jeong, W.I.5    Lafdil, F.6
  • 27
    • 0028052968 scopus 로고
    • Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines
    • Baggiolini M, Dewald B, Moser B. Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines. Adv Immunol 1994; 55: 97-179.
    • (1994) Adv Immunol , vol.55 , pp. 97-179
    • Baggiolini, M.1    Dewald, B.2    Moser, B.3
  • 28
    • 0028136769 scopus 로고
    • Chemokines, inflammation, and the immune system
    • Taub DD, Oppenheim JJ. Chemokines, inflammation, and the immune system. Ther Immunol 1994; 1: 229-246.
    • (1994) Ther Immunol , vol.1 , pp. 229-246
    • Taub, D.D.1    Oppenheim, J.J.2
  • 30
    • 38549177421 scopus 로고    scopus 로고
    • Homocysteine induces monocyte chemoattractant protein-1 expression in hepatocytes mediated via activator protein-1 activation
    • Woo CW, Siow YL, O K. Homocysteine induces monocyte chemoattractant protein-1 expression in hepatocytes mediated via activator protein-1 activation. J Biol Chem 2008; 283: 1282-1292.
    • (2008) J Biol Chem , vol.283 , pp. 1282-1292
    • Woo, C.W.1    Siow, Y.L.2    O, K.3
  • 31
  • 33
    • 0038221365 scopus 로고    scopus 로고
    • C-C chemokine ligand 2/monocyte chemoattractant protein-1 directly inhibits NKT cell IL-4 production and is hepatoprotective in T cell-mediated hepatitis in the mouse
    • Ajuebor MN, Hogaboam CM, Le T, Swain MG. C-C chemokine ligand 2/monocyte chemoattractant protein-1 directly inhibits NKT cell IL-4 production and is hepatoprotective in T cell-mediated hepatitis in the mouse. J Immunol 2003; 170: 5252-5259.
    • (2003) J Immunol , vol.170 , pp. 5252-5259
    • Ajuebor, M.N.1    Hogaboam, C.M.2    Le, T.3    Swain, M.G.4
  • 34
    • 33845752399 scopus 로고    scopus 로고
    • Prevention of severe toxic liver injury and oxidative stress in MCP-1-deficient mice
    • Zamara E, Galastri S, Aleffi S, Petrai I, Aragno M, Mastrocola R, et al. Prevention of severe toxic liver injury and oxidative stress in MCP-1-deficient mice. J Hepatol 2007; 46: 230-238.
    • (2007) J Hepatol , vol.46 , pp. 230-238
    • Zamara, E.1    Galastri, S.2    Aleffi, S.3    Petrai, I.4    Aragno, M.5    Mastrocola, R.6
  • 35
    • 79955576105 scopus 로고    scopus 로고
    • Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver, and hepatotoxicity
    • Cederbaum AI. Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver, and hepatotoxicity. Dig Dis 2010; 28: 802-811.
    • (2010) Dig Dis , vol.28 , pp. 802-811
    • Cederbaum, A.I.1
  • 36
    • 33745755554 scopus 로고    scopus 로고
    • Chronic ethanol feeding increases activation of NADPH oxidase by lipopolysaccharide in rat kupffer cells: role of increased reactive oxygen in LPS-stimulated ERK1/2 activation and TNF-alpha production
    • Thakur V, Pritchard MT, McMullen MR, Wang Q, Nagy LE. Chronic ethanol feeding increases activation of NADPH oxidase by lipopolysaccharide in rat kupffer cells: role of increased reactive oxygen in LPS-stimulated ERK1/2 activation and TNF-alpha production. J Leukoc Biol 2006; 79: 1348-1356.
    • (2006) J Leukoc Biol , vol.79 , pp. 1348-1356
    • Thakur, V.1    Pritchard, M.T.2    McMullen, M.R.3    Wang, Q.4    Nagy, L.E.5
  • 37
    • 33646539166 scopus 로고    scopus 로고
    • Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver
    • Gustot T, Lemmers A, Moreno C, Nagy N, Quertinmont E, Nicaise C, et al. Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver. Hepatology 2006; 43: 989-1000.
    • (2006) Hepatology , vol.43 , pp. 989-1000
    • Gustot, T.1    Lemmers, A.2    Moreno, C.3    Nagy, N.4    Quertinmont, E.5    Nicaise, C.6
  • 39
    • 0036901080 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 (MCP-1) in the kidney: does it more than simply attract monocytes?
    • Viedt C, Orth SR. Monocyte chemoattractant protein-1 (MCP-1) in the kidney: does it more than simply attract monocytes? Nephrol Dial Transplant 2002; 17: 2043-2047.
    • (2002) Nephrol Dial Transplant , vol.17 , pp. 2043-2047
    • Viedt, C.1    Orth, S.R.2
  • 40
    • 70450225066 scopus 로고    scopus 로고
    • Molecular mechanism underlying the suppression of lipid oxidation during endotoxemia
    • Maitra U, Chang S, Singh N, Li L. Molecular mechanism underlying the suppression of lipid oxidation during endotoxemia. Mol Immunol 2009; 47: 420-425.
    • (2009) Mol Immunol , vol.47 , pp. 420-425
    • Maitra, U.1    Chang, S.2    Singh, N.3    Li, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.