Ethanol induces peroxynitrite-mediated toxicity through inactivation of NADP+-dependent isocitrate dehydrogenase and superoxide dismutase

Biochimie

Volumn 90, Issue 9, 2008, Pages 1316-1324

  Yang, Eun Sun ^a   Lee, Jin Hyup ^a   Park, Jeen Woo ^a  

^a Kyungpook National University   (South Korea)

Author keywords

Alcohol; Antioxidant enzymes; Oxidative stress; Peroxynitrite

Indexed keywords

ALCOHOL; ISOCITRATE DEHYDROGENASE; N(G) NITROARGININE METHYL ESTER; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXYNITRITE; PORPHYRIN; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ENZYME INACTIVATION; FLUORESCENCE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LIVER TOXICITY; MITOCHONDRION; NITROSATIVE STRESS; OXIDATIVE STRESS;

CELL LINE, TUMOR; CELL SURVIVAL; ENZYME ACTIVATION; ETHANOL; HUMANS; ISOCITRATE DEHYDROGENASE; MITOCHONDRIA; NADP; OXIDATION-REDUCTION; PEROXYNITROUS ACID; SUPEROXIDE DISMUTASE;

EID: 47749149538     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2008.03.001     Document Type: Article

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