-
1
-
-
1842479859
-
Diagnosis, management, and treatment of hepatitis C
-
Strader DB, Wright T, Thomas DL, Seeff LB. Diagnosis, management, and treatment of hepatitis C. HEPATOLOGY 2004;39:1147-1171.
-
(2004)
Hepatology
, vol.39
, pp. 1147-1171
-
-
Strader, D.B.1
Wright, T.2
Thomas, D.L.3
Seeff, L.B.4
-
3
-
-
0036893172
-
Management of hepatitis C 2002 (June 10-12, 2002)
-
National Institutes of Health Consensus Development Conference Statement. Management of hepatitis C 2002 (June 10-12, 2002). Gastroenterology 2002;123:2082-2099.
-
(2002)
Gastroenterology
, vol.123
, pp. 2082-2099
-
-
-
4
-
-
0029894579
-
The natural history of chronic hepatitis C infection
-
Strader DB, Seeff LB. The natural history of chronic hepatitis C infection. Eur J Gastroenterol Hepatol 1996;8:324-328.
-
(1996)
Eur J Gastroenterol Hepatol
, vol.8
, pp. 324-328
-
-
Strader, D.B.1
Seeff, L.B.2
-
5
-
-
0035934568
-
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
-
Manns MP, McHutchison JG, Gordon SC, Rustgi VK, Shiffman M, Reindollar R, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001;358:958-965.
-
(2001)
Lancet
, vol.358
, pp. 958-965
-
-
Manns, M.P.1
McHutchison, J.G.2
Gordon, S.C.3
Rustgi, V.K.4
Shiffman, M.5
Reindollar, R.6
-
6
-
-
0037179698
-
Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
-
Fried MW, Shiffman ML, Reddy KR, Smith C, Marinos G, Goncales FL Jr, et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002;347:975-982.
-
(2002)
N Engl J Med
, vol.347
, pp. 975-982
-
-
Fried, M.W.1
Shiffman, M.L.2
Reddy, K.R.3
Smith, C.4
Marinos, G.5
Goncales Jr., F.L.6
-
7
-
-
1242269422
-
Hepatitis C: Development of new drugs and clinical trials: Promises and pitfalls. Summary of an AASLD hepatitis single topic conference, Chicago, IL, February 27-March 1, 2003
-
Pawlotsky JM, McHutchison JG. Hepatitis C: development of new drugs and clinical trials: promises and pitfalls. Summary of an AASLD hepatitis single topic conference, Chicago, IL, February 27-March 1, 2003. HEPATOLOGY 2004;39:554-567.
-
(2004)
Hepatology
, vol.39
, pp. 554-567
-
-
Pawlotsky, J.M.1
McHutchison, J.G.2
-
8
-
-
0041821999
-
Evasive maneuvers by hepatitis C virus
-
Lindenbach BD, Rice CM. Evasive maneuvers by hepatitis C virus. HEPATOLOGY 2003;38:769-771.
-
(2003)
Hepatology
, vol.38
, pp. 769-771
-
-
Lindenbach, B.D.1
Rice, C.M.2
-
9
-
-
0037333918
-
In vitro selection and characterization of hepatitis C virus serine protease variants resistant to an active-site peptide inhibitor
-
Trozzi C, Bartholomew L, Ceccacci A, Biasiol G, Pacini L, Altamura S, et al. In vitro selection and characterization of hepatitis C virus serine protease variants resistant to an active-site peptide inhibitor. J Virol 2003;77:3669-3679.
-
(2003)
J Virol
, vol.77
, pp. 3669-3679
-
-
Trozzi, C.1
Bartholomew, L.2
Ceccacci, A.3
Biasiol, G.4
Pacini, L.5
Altamura, S.6
-
11
-
-
2342584790
-
Toll-like receptors and the host defense against microbial pathogens: Bringing specificity to the innate-immune system
-
Netea MG, van der Graaf C, Van der Meer JW, Kullberg BJ. Toll-like receptors and the host defense against microbial pathogens: bringing specificity to the innate-immune system. J Leukoc Biol 2004;75:749-755.
-
(2004)
J Leukoc Biol
, vol.75
, pp. 749-755
-
-
Netea, M.G.1
Van Der Graaf, C.2
Van Der Meer, J.W.3
Kullberg, B.J.4
-
12
-
-
3142654210
-
Inferences, questions and possibilities in toll-like receptor signalling
-
Beutler B. Inferences, questions and possibilities in toll-like receptor signalling. Nature 2004;430:257-263.
-
(2004)
Nature
, vol.430
, pp. 257-263
-
-
Beutler, B.1
-
13
-
-
1642348819
-
Immunology. After the toll rush
-
O'Neill LA. Immunology. After the toll rush. Science 2004;303:1481-1482.
-
(2004)
Science
, vol.303
, pp. 1481-1482
-
-
O'Neill, L.A.1
-
14
-
-
0038651180
-
Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of toll-like receptor 7
-
Lee J, Chuang TH, Redecke V, She L, Pitha PM, Carson DA, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of toll-like receptor 7. Proc Natl Acad Sci U S A 2003; 100:6646-6651.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 6646-6651
-
-
Lee, J.1
Chuang, T.H.2
Redecke, V.3
She, L.4
Pitha, P.M.5
Carson, D.A.6
-
15
-
-
0242391997
-
The toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily
-
Heil F, Ahmad-Nejad P, Hemmi H, Hochrein H, Ampenberger F, Gellert T, et al. The toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur J Immunol 2003;33:2987-2997.
-
(2003)
Eur J Immunol
, vol.33
, pp. 2987-2997
-
-
Heil, F.1
Ahmad-Nejad, P.2
Hemmi, H.3
Hochrein, H.4
Ampenberger, F.5
Gellert, T.6
-
16
-
-
0037460116
-
Recognition of pathogen-associated molecular patterns by TLR family
-
Akira S, Hemmi H. Recognition of pathogen-associated molecular patterns by TLR family. Immunol Lett 2003;85:85-95.
-
(2003)
Immunol Lett
, vol.85
, pp. 85-95
-
-
Akira, S.1
Hemmi, H.2
-
17
-
-
0036008014
-
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
Hemmi H, Kaisho T, Takeuchi O, Sato S, Sanjo H, Hoshino K, et al. Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 2002;3:196-200.
-
(2002)
Nat Immunol
, vol.3
, pp. 196-200
-
-
Hemmi, H.1
Kaisho, T.2
Takeuchi, O.3
Sato, S.4
Sanjo, H.5
Hoshino, K.6
-
18
-
-
0025157169
-
Thiazolo[4,5-d]pyrimidine nucleosides: The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents
-
Nagahara K, Anderson JD, Kini GD, Dalley NK, Larson SB, Smee DF, et al. Thiazolo[4,5-d]pyrimidine nucleosides: the synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. J Med Chem 1990;33:407-415.
-
(1990)
J Med Chem
, vol.33
, pp. 407-415
-
-
Nagahara, K.1
Anderson, J.D.2
Kini, G.D.3
Dalley, N.K.4
Larson, S.B.5
Smee, D.F.6
-
19
-
-
0024414910
-
Broad-spectrum in vivo antiviral activity of 7-thia-8-oxoguanosine, a novel immunopotentiating agent
-
Smee DF, Alaghamandan HA, Cottam HB, Sharma BS, Jolley WB, Robins RK. Broad-spectrum in vivo antiviral activity of 7-thia-8-oxoguanosine, a novel immunopotentiating agent. Antimicrob Agents Chemother 1989;33:1487-1492.
-
(1989)
Antimicrob Agents Chemother
, vol.33
, pp. 1487-1492
-
-
Smee, D.F.1
Alaghamandan, H.A.2
Cottam, H.B.3
Sharma, B.S.4
Jolley, W.B.5
Robins, R.K.6
-
20
-
-
0025093463
-
Antiviral activity of the novel immune modulator 7-thia-8-oxoguanosine
-
Smee DF, Alaghamandan HA, Cottam HB, Jolley WB, Robbins RK. Antiviral activity of the novel immune modulator 7-thia-8-oxoguanosine. J Biol Response Mod 1990;9:24-32.
-
(1990)
J Biol Response Mod
, vol.9
, pp. 24-32
-
-
Smee, D.F.1
Alaghamandan, H.A.2
Cottam, H.B.3
Jolley, W.B.4
Robbins, R.K.5
-
21
-
-
0025845297
-
Prophylactic and therapeutic activities of 7-thia-8-oxoguanosine against Punta Toro virus infections in mice
-
Smee DF, Huffman JH, Gessaman AC, Huggins JW, Sidwell RW. Prophylactic and therapeutic activities of 7-thia-8-oxoguanosine against Punta Toro virus infections in mice. Antiviral Res 1991;15:229-239.
-
(1991)
Antiviral Res
, vol.15
, pp. 229-239
-
-
Smee, D.F.1
Huffman, J.H.2
Gessaman, A.C.3
Huggins, J.W.4
Sidwell, R.W.5
-
22
-
-
0036208536
-
Viral kinetics in genotype 1 chronic hepatitis C patients during therapy with 2 different doses of peginterferon alpha-2b plus ribavirin
-
Buti M, Sanchez-Avila F, Lurie Y, Stalgis C, Valdes A, Martell M, et al. Viral kinetics in genotype 1 chronic hepatitis C patients during therapy with 2 different doses of peginterferon alpha-2b plus ribavirin. HEPATOLOGY 2002;35:930-936.
-
(2002)
Hepatology
, vol.35
, pp. 930-936
-
-
Buti, M.1
Sanchez-Avila, F.2
Lurie, Y.3
Stalgis, C.4
Valdes, A.5
Martell, M.6
-
23
-
-
0034324083
-
Pegylated interferon-alpha2b: Pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data
-
Hepatitis C Intervention Therapy Group
-
Glue P, Fang JW, Rouzier-Panis R, Raffanel C, Sabo R, Gupta SK, et al. Pegylated interferon-alpha2b: pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data. Hepatitis C Intervention Therapy Group. Clin Pharmacol Ther 2000;68:556-567.
-
(2000)
Clin Pharmacol Ther
, vol.68
, pp. 556-567
-
-
Glue, P.1
Fang, J.W.2
Rouzier-Panis, R.3
Raffanel, C.4
Sabo, R.5
Gupta, S.K.6
-
24
-
-
0037806029
-
Effect of ribavirin on hepatitis C viral kinetics in patients treated with pegylated interferon
-
Herrmann E, Lee JH, Marinos G, Modi M, Zeuzem S. Effect of ribavirin on hepatitis C viral kinetics in patients treated with pegylated interferon. HEPATOLOGY 2003;37:1351-1358.
-
(2003)
Hepatology
, vol.37
, pp. 1351-1358
-
-
Herrmann, E.1
Lee, J.H.2
Marinos, G.3
Modi, M.4
Zeuzem, S.5
-
25
-
-
4344625164
-
Viral dynamics and pharmacokinetics of peginterferon alpha-2a and peginterferon alpha-2b in naive patients with chronic hepatitis C; a randomized, controlled study
-
Bruno R, Sacchi P, Ciappina V, Zochetti C, Patruno S, Maiocchi L, et al. Viral dynamics and pharmacokinetics of peginterferon alpha-2a and peginterferon alpha-2b in naive patients with chronic hepatitis C; a randomized, controlled study. Antivir Ther 2004;9:491-497.
-
(2004)
Antivir Ther
, vol.9
, pp. 491-497
-
-
Bruno, R.1
Sacchi, P.2
Ciappina, V.3
Zochetti, C.4
Patruno, S.5
Maiocchi, L.6
-
26
-
-
0027372960
-
Changes of serum 2′,5′-oligoadenylate synthetase activity during interferon treatment of chronic hepatitis C
-
Solinas A, Cossu P, Poddighe P, Tocco A, Deplano A, Garrucciu G, et al. Changes of serum 2′,5′-oligoadenylate synthetase activity during interferon treatment of chronic hepatitis C. Liver 1993;13:253-258.
-
(1993)
Liver
, vol.13
, pp. 253-258
-
-
Solinas, A.1
Cossu, P.2
Poddighe, P.3
Tocco, A.4
Deplano, A.5
Garrucciu, G.6
-
27
-
-
0030686567
-
Activity and tolerance of a continuous subcutaneous infusion of interferon-alpha2b in patients with chronic hepatitis C
-
Schenker S, Cutler D, Finch J, Tamburro CH, Affrime M, Sabo R, et al. Activity and tolerance of a continuous subcutaneous infusion of interferon-alpha2b in patients with chronic hepatitis C. J Interferon Cytokine Res 1997;17:665-670.
-
(1997)
J Interferon Cytokine Res
, vol.17
, pp. 665-670
-
-
Schenker, S.1
Cutler, D.2
Finch, J.3
Tamburro, C.H.4
Affrime, M.5
Sabo, R.6
-
28
-
-
0033817962
-
Effect of interferon treatment on serum 2′,5′-oligoadenylate synthetase levels in hepatitis C-infected patients
-
Murashima S, Kumashiro R, Ide T, Miyajima I, Hino T, Koga Y, et al. Effect of interferon treatment on serum 2′,5′-oligoadenylate synthetase levels in hepatitis C-infected patients. J Med Virol 2000;62:185-190.
-
(2000)
J Med Virol
, vol.62
, pp. 185-190
-
-
Murashima, S.1
Kumashiro, R.2
Ide, T.3
Miyajima, I.4
Hino, T.5
Koga, Y.6
-
29
-
-
0242584810
-
Upregulation of endogenous intrahepatic interferon stimulated genes during chronic hepatitis C virus infection
-
MacQuillan GC, Mamotte C, Reed WD, Jeffrey GP, Allan JE. Upregulation of endogenous intrahepatic interferon stimulated genes during chronic hepatitis C virus infection. J Med Virol 2003;70:219-227.
-
(2003)
J Med Virol
, vol.70
, pp. 219-227
-
-
MacQuillan, G.C.1
Mamotte, C.2
Reed, W.D.3
Jeffrey, G.P.4
Allan, J.E.5
-
31
-
-
0036533663
-
IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking
-
Dufour JH, Dziejman M, Liu MT, Leung JH, Lane TE, Luster AD. IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking. J Immunol 2002;168:3195-3204.
-
(2002)
J Immunol
, vol.168
, pp. 3195-3204
-
-
Dufour, J.H.1
Dziejman, M.2
Liu, M.T.3
Leung, J.H.4
Lane, T.E.5
Luster, A.D.6
-
32
-
-
7844238614
-
Ribavirin and interferon alfa-2b in chronic hepatitis C: Assessment of possible pharmacokinetic and pharmacodynamic interactions
-
Khakoo S, Glue P, Grellier L, Wells B, Bell A, Dash C, et al. Ribavirin and interferon alfa-2b in chronic hepatitis C: assessment of possible pharmacokinetic and pharmacodynamic interactions. Br J Clin Pharmacol 1998; 46:563-570.
-
(1998)
Br J Clin Pharmacol
, vol.46
, pp. 563-570
-
-
Khakoo, S.1
Glue, P.2
Grellier, L.3
Wells, B.4
Bell, A.5
Dash, C.6
-
33
-
-
0036389861
-
Pleiotropic mechanisms of ribavirin antiviral activities
-
Hong Z, Cameron CE. Pleiotropic mechanisms of ribavirin antiviral activities. Prog Drug Res 2002;59:41-69.
-
(2002)
Prog Drug Res
, vol.59
, pp. 41-69
-
-
Hong, Z.1
Cameron, C.E.2
-
34
-
-
0141755423
-
The role of ribavirin-induced mutagenesis in HCV therapy: A concept or a fact?
-
Hong Z. The role of ribavirin-induced mutagenesis in HCV therapy: a concept or a fact? HEPATOLOGY 2003;38;807-810.
-
(2003)
Hepatology
, vol.38
, pp. 807-810
-
-
Hong, Z.1
-
35
-
-
2542476148
-
Immunopharmacology of CpG oligodeoxynucleotides and ribavirin
-
Vollmer J, Rankin R, Hartmann H, Jurk M, Samulowitz U, Wader T, et al. Immunopharmacology of CpG oligodeoxynucleotides and ribavirin. Antimicrob Agents Chemother 2004;48:2314-2317.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2314-2317
-
-
Vollmer, J.1
Rankin, R.2
Hartmann, H.3
Jurk, M.4
Samulowitz, U.5
Wader, T.6
-
36
-
-
2342531101
-
Antiviral drugs in current clinical use
-
De Clercq E. Antiviral drugs in current clinical use. J Clin Virol 2004;30: 115-133.
-
(2004)
J Clin Virol
, vol.30
, pp. 115-133
-
-
De Clercq, E.1
-
37
-
-
0038580440
-
A multicenter study of recombinant human interleukin 12 for the treatment of chronic hepatitis C virus infection in patients nonresponsive to previous therapy
-
Pockros PJ, Patel K, O'Brien C, Tong M, Smith C, Rustgi V, et al. A multicenter study of recombinant human interleukin 12 for the treatment of chronic hepatitis C virus infection in patients nonresponsive to previous therapy. HEPATOLOGY 2003;37:1368-1374.
-
(2003)
Hepatology
, vol.37
, pp. 1368-1374
-
-
Pockros, P.J.1
Patel, K.2
O'Brien, C.3
Tong, M.4
Smith, C.5
Rustgi, V.6
-
38
-
-
0036905778
-
The psychoneuroimmuno-pathophysiology of cytokine-induced depression in humans
-
Wichers M, Maes M. The psychoneuroimmuno-pathophysiology of cytokine-induced depression in humans. Int J Neuropsychopharmacol 2002; 5:375-388.
-
(2002)
Int J Neuropsychopharmacol
, vol.5
, pp. 375-388
-
-
Wichers, M.1
Maes, M.2
-
39
-
-
0036780681
-
Toll-like receptors as potential therapeutic targets for multiple diseases
-
Zuany-Arnorim C, Hastewell J, Walker C. Toll-like receptors as potential therapeutic targets for multiple diseases. Nat Rev Drug Discov 2002;1: 797-807.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 797-807
-
-
Zuany-Arnorim, C.1
Hastewell, J.2
Walker, C.3
-
40
-
-
0043198258
-
Novel therapeutic strategies based on toll-like receptor signaling
-
Lawton JA, Ghosh P. Novel therapeutic strategies based on toll-like receptor signaling. Curr Opin Chem Biol 2003;7:446-451.
-
(2003)
Curr Opin Chem Biol
, vol.7
, pp. 446-451
-
-
Lawton, J.A.1
Ghosh, P.2
-
41
-
-
0042493163
-
Therapeutic targeting of toll-like receptors for inflammatory and infectious diseases
-
O'Neill LA. Therapeutic targeting of toll-like receptors for inflammatory and infectious diseases. Curr Opin Pharmacol 2003;3:396-403.
-
(2003)
Curr Opin Pharmacol
, vol.3
, pp. 396-403
-
-
O'Neill, L.A.1
-
43
-
-
33646591324
-
A phase IIa placebo-controlled, double blind trial to determine the safety, tolerability, and pk/pd of an oral interferon inducer
-
Pockros P, Tong M, Wright T. A phase IIa placebo-controlled, double blind trial to determine the safety, tolerability, and pk/pd of an oral interferon inducer. Gastroenterology 2003;124(Suppl 1):76A.
-
(2003)
Gastroenterology
, vol.124
, Issue.SUPPL. 1
-
-
Pockros, P.1
Tong, M.2
Wright, T.3
|