Alcohol-induced S-adenosylhomocysteine accumulation in the liver sensitizes to TNF hepatotoxicity: Possible involvement of mitochondrial S-adenosylmethionine transport

Biochemical Pharmacology

Volumn 74, Issue 3, 2007, Pages 521-531

  Song, Zhenyuan ^a   Zhou, Zhanxiang ^a   Song, Ming ^a   Uriarte, Silvia ^a   Chen, Theresa ^a   Deaciuc, Ion ^a   McClain, Craig J ^a,b  

^a University of Louisville School of Medicine   (United States)

^b Louisville VAMC   (United States)

Author keywords

Liver; Mitochondria; S adenosylhomocysteine; S adenosylmethionine; Tumor necrosis factor

Indexed keywords

3 DEAZA ADENOSINE; ADENOSINE; ALCOHOL; HYDROLASE INHIBITOR; LIPOPOLYSACCHARIDE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ALCOHOL CONSUMPTION; ARTICLE; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; CYTOTOXICITY; DRUG SENSITIZATION; HUMAN; HUMAN CELL; LIVER CELL; LIVER TOXICITY; MALE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN TRANSPORT; RAT;

ANIMALS; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME-LINKED IMMUNOSORBENT ASSAY; ETHANOL; LIVER; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA, LIVER; RATS; RATS, SPRAGUE-DAWLEY; S-ADENOSYLHOMOCYSTEINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34250782784     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.05.005     Document Type: Article

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