Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice

Journal of Hepatology

Volumn 55, Issue 5, 2011, Pages 1086-1094

  Kamari, Yehuda ^a,b   Shaish, Aviv ^a   Vax, Einav ^a,b   Shemesh, Shay ^a,c   Kandel Kfir, Michal ^a   Arbel, Yaron ^a   Olteanu, Sarita ^a,b   Barshack, Iris ^a,b   Dotan, Shahar ^d   Voronov, Elana ^d   Dinarello, Charles A ^e   Apte, Ron N ^d   Harats, Dror ^a,b  

^a SHEBA MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c BAR ILAN UNIVERSITY   (Israel)

^d BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^e UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Cytokines; Fatty liver; IL 1; Inflammation; Lipid metabolism; Mouse model; Steatohepatitis

Indexed keywords

AMYLOID A PROTEIN; CHOLESTEROL; COLLAGEN; CXCL1 CHEMOKINE; GELATINASE B; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; LYMPHOTOXIN; MESSENGER RNA; PADGEM PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROGENIC DIET; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FATTY LIVER; FEMALE; HYPERCHOLESTEROLEMIA; LIVER CELL; LIVER FIBROSIS; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FOLDING; PROTEIN FUNCTION; STEADY STATE;

ANALYSIS OF VARIANCE; ANIMALS; CHEMOKINE CXCL1; COLLAGEN; DIET, ATHEROGENIC; DISEASE PROGRESSION; FATTY LIVER; GENE EXPRESSION; HEPATITIS; HYPERCHOLESTEROLEMIA; INTERLEUKIN-1; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; LIVER CIRRHOSIS; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; P-SELECTIN; RNA, MESSENGER; SERUM AMYLOID A PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80054737370     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2011.01.048     Document Type: Article

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