Peroxynitrite alters the catalytic activity of rodent liver proteasome in vitro and in vivo

Hepatology

Volumn 40, Issue 3, 2004, Pages 574-582

  Osna, Natalia A ^a,b   Haorah, James ^b   Krutik, Viatcheslav M ^d   Donohue Jr , Terrence M ^a,b,c  

^a VA NEBRASKA WESTERN IOWA HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^d UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

20S PROTEASOME; 26S PROTEASOME; ANTIGEN; LINSIDOMINE; N ACETYL S NITROSOPENICILLAMINE; PEPTIDASE; PEPTIDE; PEROXYNITRITE; PROTEASOME; PROTEIN S 100; UNCLASSIFIED DRUG; 3 MORPHOLINO SYDNONIMINE; 3-MORPHOLINO-SYDNONIMINE; CYSTEINE PROTEINASE; DRUG DERIVATIVE; MOLSIDOMINE; MULTIENZYME COMPLEX; PEROXYNITROUS ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CATALYST; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME REGULATION; HUMAN; HUMAN CELL; LIVER; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; METABOLISM;

ANIMALS; CATALYSIS; CYSTEINE ENDOPEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; LIVER; MICE; MICE, INBRED C57BL; MOLSIDOMINE; MULTIENZYME COMPLEXES; PEROXYNITROUS ACID; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; S-NITROSO-N-ACETYLPENICILLAMINE;

EID: 4544304395     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.20352     Document Type: Article

References (31)

1. Rubbo H, Darley-Usmar V, Freeman BA. Nitric oxide regulation of tissue free radical injury. Chem Res Toxicol 1996;9:809-820.
2. Stadtman ER, Berlett BS. Reactive oxygen-mediated protein oxidation in aging and disease. Drug Metab Rev 1998;30:225-243.
3. Khan IA, Matsuura T, Kasper LH. Inducible nitric oxide synthase is not required for long-term vaccine-based immunity against Toxoplasma gondii. J Immunol 1998;161:2994-3000.
4. Ischiropoulos H, al-Mehdi AB. Peroxynitrite-mediated oxidative protein modifications. FEBS Lett 1995;364:279-282.
5. Lee MH, Hyun DH, Jenner P, Halliwell B. Effect of proteasome inhibition on cellular oxidative damage, antioxidant defences and nitric oxide production. J Neurochem 2001;78:32-41.
6. Zima T, Fialova L, Mestek O, Janebova M, Crkovska J, Malbohan I, et al. Oxidative stress, metabolism of ethanol and alcohol-related diseases. J Biomed Sci 2001;8:59-70.
7. Kessova IG, Ho YS, Thung S, Cederbaum AI. Alcohol-induced liver injury in mice lacking Cu, Zn-superoxide dismutase. HEPATOLOGY 2003;38:1136-1145.
8. Bardag-Gorce F, Yuan QX, Li J, French BA, Fang C, Ingelman-Sundberg M, et al. The effect of ethanol-induced cytochrome p4502E1 on the inhibition of proteasome activity by alcohol. Biochem Biophys Res Commun 2000;279:23-29.
9. French SW, Mayer RJ, Bardag-Gorce F, Ingelman-Sundberg M, Rouach H, Neve And E, et al. The ubiquitin-proteasome 26S pathway in liver cell protein turnover: effect of ethanol and drugs. Alcohol Clin Exp Res 2001;25:2255-2295.
10. Donohue TM Jr, Zetterman RK, Zhang-Gouillon ZQ, French SW. Peptidase activities of the multicatalytic protease in rat liver after voluntary and intragastric ethanol administration. HEPATOLOGY 1998;28:486-491.
11. Strack PR, Waxman L, Fagan JM. Activation of the multicatalytic endopeptidase by oxidants. Effects on enzyme structure. Biochemistry 1996;35:7142-7149.
12. Reinheckel T, Sitte N, Ullrich O, Kuckelkorn U, Davies KJ, Grune T. Comparative resistance of the 20S and 26S proteasome to oxidative stress. Biochem J 1998;335(Pt 3):637-642.
13. Amici M, Lupidi G, Angeletti M, Fioretti E, Eleuteri AM. Peroxynitrite-induced oxidation and its effects on isolated proteasomal systems. Free Radic Biol Med 2003;34:987-996.
14. Cascio P, Hilton C, Kisselev AF, Rock KL, Goldberg AL. 26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide. EMBO J 2001;20:2357-2366.
15. Grune T, Blasig IE, Sitte N, Roloff B, Haseloff R, Davies KJ. Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome. J Biol Chem 1998;273:10857-10862.
16. Grune T, Klotz LO, Gieche J, Rudeck M, Sies H. Protein oxidation and proteolysis by the nonradical oxidants singlet oxygen or peroxynitrite. Free Radic Biol Med 2001;30:1243-1253.
17. Gieche J, Mehlhase J, Licht A, Zacke T, Sitte N, Grune T. Protein oxidation and proteolysis in RAW264.7 macrophages: effects of PMA activation. Biochim Biophys Acta 2001;1538:321-328.
18. Beyette JR, Hubbell T, Monaco JJ. Purification of 20S proteasomes. Methods Mol Biol 2001;156:1-16.
19. Hamel FG, Bennett RG, Harmon KS, Duckworth WC. Insulin inhibition of proteasome activity in intact cells. Biochem Biophys Res Commun 1997;234:671-674.
20. Osna NA, Clemens DL, Donohue TM Jr. Interferon gamma enhances proteasome activity in recombinant Hep G2 cells that express cytochrome P4502E1: modulation by ethanol. Biochem Pharmacol 2003;66:697-710.
21. Baraona E, Zeballos GA, Shoichet L, Mak KM, Lieber CS. Ethanol consumption increases nitric oxide production in rats, and its peroxynitrite-mediated toxicity is attenuated by polyenylphosphatidylcholine. Alcohol Clin Exp Res 2002;26:883-889.
22. Gow AJ, Ischiropoulos H. Nitric oxide chemistry and cellular signaling. J Cell Physiol 2001;187:277-282.
23. Bochtler M, Ditzel L, Groll M, Hartmann C, Huber R. The proteasome. Annu Rev Biophys Biomol Struct 1999;28:295-317.
24. Sijts A, Sun Y, Janek K, Kral S, Paschen A, Schadendorf D, et al. The role of the proteasome activator PA28 in MHC class I antigen processing. Mol Immunol 2002;39:165-169.
25. Ding JW, Wang K, Brems JJ, Gamelli RL. Protection against concanavalin A-induced hepatocyte apoptosis by molsidomine is time-dependent. J Am Coll Surg 2004;198:67-77.
26. Kuehn L, Dahlmann B. Proteasome activator PA28 and its interaction with 20 S proteasomes. Arch Biochem Biophys 1996;329:87-96.
27. Joshi-Barve S, Barve SS, Butt W, Klein J, McClain CJ. Inhibition of proteasome function leads to NF-kappaB-independent IL-8 expression in human hepatocytes. HEPATOLOGY 2003;38:1178-1187.
28. Robinson VK, Sato E, Nelson DK, Camhi SL, Robbins RA, Hoyt JC. Peroxynitrite inhibits inducible (type 2) nitric oxide synthase in murine lung epithelial cells in vitro. Free Radic Biol Med 2001;30:986-991.
29. Lee JH, Yang ES, Park JW. Inactivation of NADP+-dependent isocitrate dehydrogenase by peroxynitrite: implications for cytotoxicity and alcohol-induced liver injury. J Biol Chem 2003;278:51360-51371.
30. Souza JM, Choi I, Chen Q, Weisse M, Daikhin E, Yudkoff M, et al. Proteolytic degradation of tyrosine nitrated proteins. Arch Biochem Biophys 2000;380:360-366.
31. Bardag-Gorce F, French BA, Li J, Riley NE, Yuan QX, Valinluck V, et al. The importance of cycling of blood alcohol levels in the pathogenesis of experimental alcoholic liver disease in rats. Gastroenterology 2002;123:325-335.