Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 5, 2009, Pages 1548-1553

  Machida, Keigo ^a   Tsukamoto, Hidekazu ^a,b   Mkrtchyan, Hasmik ^a   Duan, Lewei ^a   Dynnyk, Alla ^a   Liu, Helene Minyi ^a   Asahina, Kinji ^a   Govindarajan, Sugantha ^a   Ray, Ratna ^c   James, Jing Hsiung ^a   Seki, Ekihiro ^d   Deshaies, Raymond ^e   Miyake, Kensuke ^f   Lai, Michael M C ^a,g  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^f UNIVERSITY OF TOKYO   (Japan)

^g NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CELL MARKER; LIPOPOLYSACCHARIDE; LIVER PROTEIN; NONSTRUCTURAL PROTEIN 5A; SHORT HAIRPIN RNA; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR NANOG; BIOLOGICAL MARKER; HOMEODOMAIN PROTEIN; NANOG PROTEIN, MOUSE; NS 5 PROTEIN, HEPATITIS C VIRUS; NS-5 PROTEIN, HEPATITIS C VIRUS; VIRUS PROTEIN;

ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER RISK; CARCINOGENESIS; DNA FLANKING REGION; ENDOTOXEMIA; HEPATITIS C VIRUS; HUMAN; IMMUNOBLOTTING; LIVER CANCER; LIVER DISEASE; LIVER INJURY; LIVER TUMOR; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEM CELL; STEM CELL TRANSPLANTATION; TRANSGENIC MOUSE; TUMOR GROWTH; ANIMAL; CHEMICALLY INDUCED DISORDER; COCARCINOGENESIS; GENETICS; PATHOPHYSIOLOGY; PHYSIOLOGY; VIROLOGY;

HEPATITIS C VIRUS; MUS;

ANIMALS; BIOLOGICAL MARKERS; COCARCINOGENESIS; ETHANOL; HEPACIVIRUS; HOMEODOMAIN PROTEINS; HUMANS; LIPOPOLYSACCHARIDES; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, TRANSGENIC; TOLL-LIKE RECEPTOR 4; VIRAL NONSTRUCTURAL PROTEINS;

EID: 60849102149     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0807390106     Document Type: Article

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