Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease

Seminars in Liver Disease

Volumn 28, Issue 4, 2008, Pages 360-369

  Malhi, Harmeet ^a   Gores, Gregory J ^a  

^a MAYO CLINIC   (United States)

Author keywords

Bim; C jun N terminal kinase; Hepatocyte injury; Oleic acid; Palmitic acid

Indexed keywords

BH3 PROTEIN; CERAMIDE DERIVATIVE; CHOLESTEROL; DEATH RECEPTOR; FATTY ACID; PROTEIN BAX; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR; TRIACYLGLYCEROL;

ABNORMALLY HIGH SUBSTRATE CONCENTRATION IN BLOOD; APOPTOSIS; CELL DEATH; CLINICAL FEATURE; CORRELATION ANALYSIS; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; FATTY ACID BLOOD LEVEL; GENE EXPRESSION REGULATION; HEPATITIS; HISTOPATHOLOGY; HUMAN; INSULIN RESISTANCE; LIPID LIVER LEVEL; LIVER CELL; LIVER FIBROSIS; LIVER INJURY; LYSOSOME; MITOCHONDRION; MOLECULAR BIOLOGY; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

APOPTOSIS; ENDOPLASMIC RETICULUM; FATTY ACIDS, NONESTERIFIED; FATTY LIVER; HEPATOCYTES; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER; MITOCHONDRIA, LIVER; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 56649094325     PISSN: 02728087     EISSN: 10988971     Source Type: Journal    
DOI: 10.1055/s-0028-1091980     Document Type: Review

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