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Volumn 41, Issue 1, 2012, Pages 79-105

Environmental chemical exposures and human epigenetics

Author keywords

Disease susceptibility; Environmental chemicals; Epigenetics

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ARSENIC; BENZENE; CADMIUM; CYCLONITE; DIETHYLSTILBESTROL; DIOXIN; DRINKING WATER; ENVIRONMENTAL CHEMICAL; HEAVY METAL; MERCURY; MICRORNA; NICKEL; PESTICIDE;

EID: 84863338135     PISSN: 03005771     EISSN: 14643685     Source Type: Journal    
DOI: 10.1093/ije/dyr154     Document Type: Article
Times cited : (363)

References (385)
  • 2
    • 77953812272 scopus 로고    scopus 로고
    • Environmental epigenetics
    • Bollati V, Baccarelli A. Environmental epigenetics. Heredity 2010;105:105-12.
    • (2010) Heredity , vol.105 , pp. 105-112
    • Bollati, V.1    Baccarelli, A.2
  • 4
    • 34548757364 scopus 로고    scopus 로고
    • Epigenetic reprogramming and imprinting in origins of disease
    • Tang WY, Ho SM. Epigenetic reprogramming and imprinting in origins of disease. Rev Endocr Metab Disord 2007;8:173-82.
    • (2007) Rev Endocr Metab Disord , vol.8 , pp. 173-182
    • Tang, W.Y.1    Ho, S.M.2
  • 5
    • 47849083984 scopus 로고    scopus 로고
    • Epigenetic interplay between histone modifications and DNA methylation in gene silencing
    • Vaissiere T, Sawan C, Herceg Z. Epigenetic interplay between histone modifications and DNA methylation in gene silencing. Mutat Res 2008;659:40-48.
    • (2008) Mutat Res , vol.659 , pp. 40-48
    • Vaissiere, T.1    Sawan, C.2    Herceg, Z.3
  • 6
    • 0042528729 scopus 로고    scopus 로고
    • Heterochromatin and epigenetic control of gene expression
    • Grewal SI, Moazed D. Heterochromatin and epigenetic control of gene expression. Science 2003;301: 798-802.
    • (2003) Science , vol.301 , pp. 798-802
    • Grewal, S.I.1    Moazed, D.2
  • 7
    • 0035839126 scopus 로고    scopus 로고
    • Epigenetic reprogramming in mammalian development
    • Reik W, Dean W, Walter J. Epigenetic reprogramming in mammalian development. Science 2001;293: 1089-93.
    • (2001) Science , vol.293 , pp. 1089-1093
    • Reik, W.1    Dean, W.2    Walter, J.3
  • 8
    • 67749129297 scopus 로고    scopus 로고
    • Epigenetics and environmental chemicals
    • Baccarelli A, Bollati V. Epigenetics and environmental chemicals. Curr Opin Pediatr 2009;21:243-51.
    • (2009) Curr Opin Pediatr , vol.21 , pp. 243-251
    • Baccarelli, A.1    Bollati, V.2
  • 9
    • 79955856345 scopus 로고    scopus 로고
    • Therapeutic prospects for epigenetic modulation
    • Heightman TD. Therapeutic prospects for epigenetic modulation. Expert Opin Ther Targets 2011;15:729-40.
    • (2011) Expert Opin Ther Targets , vol.15 , pp. 729-740
    • Heightman, T.D.1
  • 10
    • 78649379677 scopus 로고    scopus 로고
    • Epidemiology of stress and asthma: from constricting communities and fragile families to epigenetics
    • Wright RJ. Epidemiology of stress and asthma: from constricting communities and fragile families to epigenetics. Immunol Allergy Clin North Am 2011;31:19-39.
    • (2011) Immunol Allergy Clin North Am , vol.31 , pp. 19-39
    • Wright, R.J.1
  • 11
    • 0016345881 scopus 로고
    • 5-Methylcytosine localised in mammalian constitutive heterochromatin
    • Miller OJ, Schnedl W, Allen J, Erlanger BF. 5-Methylcytosine localised in mammalian constitutive heterochromatin. Nature 1974;251:636-37.
    • (1974) Nature , vol.251 , pp. 636-637
    • Miller, O.J.1    Schnedl, W.2    Allen, J.3    Erlanger, B.F.4
  • 12
    • 0030840954 scopus 로고    scopus 로고
    • Cytosine methylation and the ecology of intragenomic parasites
    • Yoder JA, Walsh CP, Bestor TH. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet 1997; 13:335-40.
    • (1997) Trends Genet , vol.13 , pp. 335-340
    • Yoder, J.A.1    Walsh, C.P.2    Bestor, T.H.3
  • 13
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002;3:415-28.
    • (2002) Nat Rev Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 14
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002;16:6-21.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 16
    • 0242584454 scopus 로고    scopus 로고
    • Chromosomal instability and tumors promoted by DNA hypomethylation
    • Eden A, Gaudet F, Waghmare A, Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science 2003;300:455.
    • (2003) Science , vol.300 , pp. 455
    • Eden, A.1    Gaudet, F.2    Waghmare, A.3    Jaenisch, R.4
  • 17
    • 0242584449 scopus 로고    scopus 로고
    • Induction of tumors in mice by genomic hypomethylation
    • Gaudet F, Hodgson JG, Eden A et al. Induction of tumors in mice by genomic hypomethylation. Science 2003;300: 489-92.
    • (2003) Science , vol.300 , pp. 489-492
    • Gaudet, F.1    Hodgson, J.G.2    Eden, A.3
  • 18
    • 17444417521 scopus 로고    scopus 로고
    • Cancer epigenetics
    • (Spec No 1)
    • Laird PW. Cancer epigenetics. Hum Mol Genet 2005; (Spec No 1):R65-76.
    • (2005) Hum Mol Genet
    • Laird, P.W.1
  • 19
    • 0018670426 scopus 로고
    • A ubiquitous family of repeated DNA sequences in the human genome
    • Houck CM, Rinehart FP, Schmid CW. A ubiquitous family of repeated DNA sequences in the human genome. J Mol Biol 1979;132:289-306.
    • (1979) J Mol Biol , vol.132 , pp. 289-306
    • Houck, C.M.1    Rinehart, F.P.2    Schmid, C.W.3
  • 20
    • 2342557977 scopus 로고    scopus 로고
    • A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
    • Yang AS, Estecio MR, Doshi K, Kondo Y, Tajara EH, Issa JP. A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res 2004;32:e38.
    • (2004) Nucleic Acids Res , vol.32
    • Yang, A.S.1    Estecio, M.R.2    Doshi, K.3    Kondo, Y.4    Tajara, E.H.5    Issa, J.P.6
  • 21
    • 29244490041 scopus 로고    scopus 로고
    • Analysis of repetitive element DNA methylation by MethyLight
    • Weisenberger DJ, Campan M, Long TI et al. Analysis of repetitive element DNA methylation by MethyLight. Nucleic Acids Res 2005;33:6823-36.
    • (2005) Nucleic Acids Res , vol.33 , pp. 6823-6836
    • Weisenberger, D.J.1    Campan, M.2    Long, T.I.3
  • 22
    • 84858680246 scopus 로고    scopus 로고
    • Predictors of global methylation levels in blood DNA of healthy subjects: a combined analysis
    • Zhu ZZ, Hou L, Bollati V et al. Predictors of global methylation levels in blood DNA of healthy subjects: a combined analysis. Int J Epidemiol 2012;41:126-39.
    • (2012) Int J Epidemiol , vol.41 , pp. 126-139
    • Zhu, Z.Z.1    Hou, L.2    Bollati, V.3
  • 23
    • 70849112745 scopus 로고    scopus 로고
    • Association between global DNA hypomethylation in leukocytes and risk of breast cancer
    • Choi JY, James SR, Link PA et al. Association between global DNA hypomethylation in leukocytes and risk of breast cancer. Carcinogenesis 2009;30:1889-97.
    • (2009) Carcinogenesis , vol.30 , pp. 1889-1897
    • Choi, J.Y.1    James, S.R.2    Link, P.A.3
  • 24
    • 77953191946 scopus 로고    scopus 로고
    • Aging and chronic sun exposure cause distinct epigenetic changes in human skin
    • Gronniger E, Weber B, Heil O et al. Aging and chronic sun exposure cause distinct epigenetic changes in human skin. PLoS Genet 2010;6:e1000971.
    • (2010) PLoS Genet , vol.6
    • Gronniger, E.1    Weber, B.2    Heil, O.3
  • 25
    • 79951497235 scopus 로고    scopus 로고
    • DNA methylation in porcine preimplantation embryos developed in vivo and produced by in vitro fertilization, parthenogenetic activation and somatic cell nuclear transfer
    • Deshmukh RS, Ostrup O, Ostrup E et al. DNA methylation in porcine preimplantation embryos developed in vivo and produced by in vitro fertilization, parthenogenetic activation and somatic cell nuclear transfer. Epigenetics 2011;6:177-87.
    • (2011) Epigenetics , vol.6 , pp. 177-187
    • Deshmukh, R.S.1    Ostrup, O.2    Ostrup, E.3
  • 27
    • 78649451968 scopus 로고    scopus 로고
    • The role of the DNA hypermethylating agent Budesonide in the decatenating activity of DNA topoisomerase II
    • Orta ML, Dominguez I, Pastor N, Cortes F, Mateos S. The role of the DNA hypermethylating agent Budesonide in the decatenating activity of DNA topoisomerase II. Mutat Res 2010;694:45-52.
    • (2010) Mutat Res , vol.694 , pp. 45-52
    • Orta, M.L.1    Dominguez, I.2    Pastor, N.3    Cortes, F.4    Mateos, S.5
  • 28
    • 59149084538 scopus 로고    scopus 로고
    • The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
    • Irizarry RA, Ladd-Acosta C, Wen B et al. The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet 2009;41:178-86.
    • (2009) Nat Genet , vol.41 , pp. 178-186
    • Irizarry, R.A.1    Ladd-Acosta, C.2    Wen, B.3
  • 29
    • 34547890019 scopus 로고    scopus 로고
    • Functions of site-specific histone acetylation and deacetylation
    • Shahbazian MD, Grunstein M. Functions of site-specific histone acetylation and deacetylation. Annu Rev Biochem 2007;76:75-100.
    • (2007) Annu Rev Biochem , vol.76 , pp. 75-100
    • Shahbazian, M.D.1    Grunstein, M.2
  • 30
    • 55449096356 scopus 로고    scopus 로고
    • Crosstalk among Histone Modifications
    • Suganuma T, Workman JL. Crosstalk among Histone Modifications. Cell 2008;135:604-07.
    • (2008) Cell , vol.135 , pp. 604-607
    • Suganuma, T.1    Workman, J.L.2
  • 31
    • 50249091120 scopus 로고    scopus 로고
    • Chemical regulation of epigenetic modifications: opportunities for new cancer therapy
    • Zheng YG, Wu J, Chen Z, Goodman M. Chemical regulation of epigenetic modifications: opportunities for new cancer therapy. Med Res Rev 2008;28:645-87.
    • (2008) Med Res Rev , vol.28 , pp. 645-687
    • Zheng, Y.G.1    Wu, J.2    Chen, Z.3    Goodman, M.4
  • 32
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 2007;128:693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 33
  • 34
    • 34547897023 scopus 로고    scopus 로고
    • Histone deacetylases and cancer
    • Glozak MA, Seto E. Histone deacetylases and cancer. Oncogene 2007;26:5420-32.
    • (2007) Oncogene , vol.26 , pp. 5420-5432
    • Glozak, M.A.1    Seto, E.2
  • 35
    • 0034051227 scopus 로고    scopus 로고
    • Acetylation of histones and transcription-related factors
    • Sterner DE, Berger SL. Acetylation of histones and transcription-related factors. Microbiol Mol Biol Rev 2000; 64:435-59.
    • (2000) Microbiol Mol Biol Rev , vol.64 , pp. 435-459
    • Sterner, D.E.1    Berger, S.L.2
  • 36
    • 0034045040 scopus 로고    scopus 로고
    • Histone deacetylases, transcriptional control, and cancer
    • Cress WD, Seto E. Histone deacetylases, transcriptional control, and cancer. J Cell Physiol 2000;184:1-16.
    • (2000) J Cell Physiol , vol.184 , pp. 1-16
    • Cress, W.D.1    Seto, E.2
  • 37
    • 46249112085 scopus 로고    scopus 로고
    • Combinatorial patterns of histone acetylations and methylations in the human genome
    • Wang Z, Zang C, Rosenfeld JA et al. Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet 2008;40:897-903.
    • (2008) Nat Genet , vol.40 , pp. 897-903
    • Wang, Z.1    Zang, C.2    Rosenfeld, J.A.3
  • 38
    • 33947513027 scopus 로고    scopus 로고
    • Regulation of histone methylation by demethylimination and demethylation
    • Klose RJ, Zhang Y. Regulation of histone methylation by demethylimination and demethylation. Nat Rev Mol Cell Biol 2007;8:307-18.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 307-318
    • Klose, R.J.1    Zhang, Y.2
  • 39
    • 27644589675 scopus 로고    scopus 로고
    • The diverse functions of histone lysine methylation
    • Martin C, Zhang Y. The diverse functions of histone lysine methylation. Nat Rev Mol Cell Biol 2005;6:838-49.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 838-849
    • Martin, C.1    Zhang, Y.2
  • 40
    • 32844468049 scopus 로고    scopus 로고
    • Histone arginine methylation and its dynamic regulation
    • Wysocka J, Allis CD, Coonrod S. Histone arginine methylation and its dynamic regulation. Front Biosci 2006;11: 344-55.
    • (2006) Front Biosci , vol.11 , pp. 344-355
    • Wysocka, J.1    Allis, C.D.2    Coonrod, S.3
  • 41
    • 49649125042 scopus 로고    scopus 로고
    • Genome-scale DNA methylation maps of pluripotent and differentiated cells
    • Meissner A, Mikkelsen TS, Gu H et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 2008;454:766-70.
    • (2008) Nature , vol.454 , pp. 766-770
    • Meissner, A.1    Mikkelsen, T.S.2    Gu, H.3
  • 43
    • 79251641860 scopus 로고    scopus 로고
    • RISC RNA sequencing for context-specific identification of in vivo microrna targets
    • Matkovich SJ, Van Booven DJ, Eschenbacher WH, Dorn GW 2nd. RISC RNA sequencing for context-specific identification of in vivo microrna targets. Circ Res 2010; 108:18-26.
    • (2010) Circ Res , vol.108 , pp. 18-26
    • Matkovich, S.J.1    Van Booven, D.J.2    Eschenbacher, W.H.3    Dorn 2nd, G.W.4
  • 44
    • 39749110034 scopus 로고    scopus 로고
    • Functional aspects of animal microRNAs
    • Williams AE. Functional aspects of animal microRNAs. Cell Mol Life Sci 2008;65:545-62.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 545-562
    • Williams, A.E.1
  • 46
    • 44449084034 scopus 로고    scopus 로고
    • The microRNA (miRNA): overview of the RNA genes that modulate gene function
    • Ying SY, Chang DC, Lin SL. The microRNA (miRNA): overview of the RNA genes that modulate gene function. Mol Biotechnol 2008;38:257-68.
    • (2008) Mol Biotechnol , vol.38 , pp. 257-268
    • Ying, S.Y.1    Chang, D.C.2    Lin, S.L.3
  • 47
    • 1942435249 scopus 로고    scopus 로고
    • Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs
    • Bartel DP, Chen CZ. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat Rev Genet 2004;5:396-400.
    • (2004) Nat Rev Genet , vol.5 , pp. 396-400
    • Bartel, D.P.1    Chen, C.Z.2
  • 48
    • 55949134303 scopus 로고    scopus 로고
    • DNA methylomes, histone codes and miRNAs: tying it all together
    • Guil S, Esteller M. DNA methylomes, histone codes and miRNAs: tying it all together. Int J Biochem Cell Biol 2009; 41:87-95.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 87-95
    • Guil, S.1    Esteller, M.2
  • 49
    • 77955252630 scopus 로고    scopus 로고
    • A dictionary on microRNAs and their putative target pathways
    • Backes C, Meese E, Lenhof HP, Keller A. A dictionary on microRNAs and their putative target pathways. Nucleic Acids Res 2010;38:4476-86.
    • (2010) Nucleic Acids Res , vol.38 , pp. 4476-4486
    • Backes, C.1    Meese, E.2    Lenhof, H.P.3    Keller, A.4
  • 50
    • 72149110396 scopus 로고    scopus 로고
    • Alzheimer's disease biomarker discovery in symptomatic and asymptomatic patients: experimental approaches and future clinical applications
    • Ho L, Fivecoat H, Wang J, Pasinetti GM. Alzheimer's disease biomarker discovery in symptomatic and asymptomatic patients: experimental approaches and future clinical applications. Exp Gerontol 2010;45:15-22.
    • (2010) Exp Gerontol , vol.45 , pp. 15-22
    • Ho, L.1    Fivecoat, H.2    Wang, J.3    Pasinetti, G.M.4
  • 51
    • 77956902892 scopus 로고    scopus 로고
    • Interpretation and applicability of microRNA data to the context of Alzheimer's and age-related diseases
    • Provost P. Interpretation and applicability of microRNA data to the context of Alzheimer's and age-related diseases. Aging 2010;2:166-69.
    • (2010) Aging , vol.2 , pp. 166-169
    • Provost, P.1
  • 52
    • 77952585703 scopus 로고    scopus 로고
    • MicroRNAs as a molecular basis for mental retardation, Alzheimer's and prion diseases
    • Provost P. MicroRNAs as a molecular basis for mental retardation, Alzheimer's and prion diseases. Brain Res 2010;1338:58-66.
    • (2010) Brain Res , vol.1338 , pp. 58-66
    • Provost, P.1
  • 53
    • 77955661579 scopus 로고    scopus 로고
    • MicroRNA-21 in cardiovascular disease
    • Cheng Y, Zhang C. MicroRNA-21 in cardiovascular disease. J Cardiovasc Transl Res 2010;3:251-55.
    • (2010) J Cardiovasc Transl Res , vol.3 , pp. 251-255
    • Cheng, Y.1    Zhang, C.2
  • 54
    • 77956892038 scopus 로고    scopus 로고
    • MicroRNA regulation as a therapeutic strategy for cardiovascular disease
    • Montgomery RL, van Rooij E. MicroRNA regulation as a therapeutic strategy for cardiovascular disease. Curr Drug Targets 2010;11:936-42.
    • (2010) Curr Drug Targets , vol.11 , pp. 936-942
    • Montgomery, R.L.1    van Rooij, E.2
  • 55
    • 77954212880 scopus 로고    scopus 로고
    • MicroRNAs target gene and signaling pathway by bioinformatics analysis in the cardiac hypertrophy
    • Shen E, Diao X, Wei C, Wu Z, Zhang L, Hu B. MicroRNAs target gene and signaling pathway by bioinformatics analysis in the cardiac hypertrophy. Biochem Biophys Res Commun 2010;397:380-85.
    • (2010) Biochem Biophys Res Commun , vol.397 , pp. 380-385
    • Shen, E.1    Diao, X.2    Wei, C.3    Wu, Z.4    Zhang, L.5    Hu, B.6
  • 57
    • 61349103883 scopus 로고    scopus 로고
    • MicroRNAs in the ontogeny of leukemias and lymphomas
    • Fabbri M, Croce CM, Calin GA. MicroRNAs in the ontogeny of leukemias and lymphomas. Leuk Lymphoma 2009;50:160-70.
    • (2009) Leuk Lymphoma , vol.50 , pp. 160-170
    • Fabbri, M.1    Croce, C.M.2    Calin, G.A.3
  • 58
    • 47149109822 scopus 로고    scopus 로고
    • MicroRNAs in normal and malignant hematopoiesis
    • Garzon R, Croce CM. MicroRNAs in normal and malignant hematopoiesis. Curr Opin Hematol 2008;15:352-58.
    • (2008) Curr Opin Hematol , vol.15 , pp. 352-358
    • Garzon, R.1    Croce, C.M.2
  • 59
    • 77954382780 scopus 로고    scopus 로고
    • mir-17-92, a cluster of miRNAs in the midst of the cancer network
    • Olive V, Jiang I, He L. mir-17-92, a cluster of miRNAs in the midst of the cancer network. Int J Biochem Cell Biol 2010;42:1348-54.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1348-1354
    • Olive, V.1    Jiang, I.2    He, L.3
  • 61
    • 77954621530 scopus 로고    scopus 로고
    • The role of molecular tests in acute myelogenous leukemia treatment decisions
    • Motyckova G, Stone RM. The role of molecular tests in acute myelogenous leukemia treatment decisions. Curr Hematol Malig Rep 2010;5:109-17.
    • (2010) Curr Hematol Malig Rep , vol.5 , pp. 109-117
    • Motyckova, G.1    Stone, R.M.2
  • 63
    • 77957378106 scopus 로고    scopus 로고
    • Diet, epigenetic, and cancer prevention
    • Chen J, Xu X. Diet, epigenetic, and cancer prevention. Adv Genet 2010;71:237-55.
    • (2010) Adv Genet , vol.71 , pp. 237-255
    • Chen, J.1    Xu, X.2
  • 64
    • 77957361864 scopus 로고    scopus 로고
    • Targeting microRNAs in cancer: rationale, strategies and challenges
    • Garzon R, Marcucci G, Croce CM. Targeting microRNAs in cancer: rationale, strategies and challenges. Nat Rev Drug Discov 2010;9:775-89.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 775-789
    • Garzon, R.1    Marcucci, G.2    Croce, C.M.3
  • 66
    • 77957333258 scopus 로고    scopus 로고
    • Induction of epigenetic alterations by dietary and other environmental factors
    • Mathers JC, Strathdee G, Relton CL. Induction of epigenetic alterations by dietary and other environmental factors. Adv Genet 2010;71:3-39.
    • (2010) Adv Genet , vol.71 , pp. 3-39
    • Mathers, J.C.1    Strathdee, G.2    Relton, C.L.3
  • 67
    • 2942644991 scopus 로고    scopus 로고
    • Human health and heavy metals exposure
    • McCally M (ed.), Boston: Massachusetts Institute of Technology
    • Howard Hu. Human health and heavy metals exposure. In: McCally M (ed.). Life Support: The Environment and Human Health. Boston: Massachusetts Institute of Technology, 2002.
    • (2002) Life Support: The Environment and Human Health
    • Hu, H.1
  • 68
    • 34848877534 scopus 로고    scopus 로고
    • Alterations of TH1/TH2 reactivity by heavy metals: possible consequences include induction of autoimmune diseases
    • Hemdan NY, Emmrich F, Faber S, Lehmann J, Sack U. Alterations of TH1/TH2 reactivity by heavy metals: possible consequences include induction of autoimmune diseases. Ann NY Acad Sci 2007;1109:129-37.
    • (2007) Ann NY Acad Sci , vol.1109 , pp. 129-137
    • Hemdan, N.Y.1    Emmrich, F.2    Faber, S.3    Lehmann, J.4    Sack, U.5
  • 69
    • 0345708255 scopus 로고    scopus 로고
    • Cadmium carcinogenesis
    • Waalkes MP. Cadmium carcinogenesis. Mutat Res 2003; 533:107-20.
    • (2003) Mutat Res , vol.533 , pp. 107-120
    • Waalkes, M.P.1
  • 70
    • 38949195955 scopus 로고    scopus 로고
    • Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium
    • Salnikow K, Zhitkovich A. Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium. Chem Res Toxicol 2008;21: 28-44.
    • (2008) Chem Res Toxicol , vol.21 , pp. 28-44
    • Salnikow, K.1    Zhitkovich, A.2
  • 71
    • 0742306716 scopus 로고    scopus 로고
    • Molecular mechanisms of arsenic carcinogenesis
    • Huang C, Ke Q, Costa M, Shi X. Molecular mechanisms of arsenic carcinogenesis. Mol Cell Biochem 2004;255: 57-66.
    • (2004) Mol Cell Biochem , vol.255 , pp. 57-66
    • Huang, C.1    Ke, Q.2    Costa, M.3    Shi, X.4
  • 72
    • 0036118694 scopus 로고    scopus 로고
    • The role of oxidative stress in mechanisms of metal-induced carcinogenesis
    • Galaris D, Evangelou A. The role of oxidative stress in mechanisms of metal-induced carcinogenesis. Crit Rev Oncol Hematol 2002;42:93-103.
    • (2002) Crit Rev Oncol Hematol , vol.42 , pp. 93-103
    • Galaris, D.1    Evangelou, A.2
  • 73
    • 0742271943 scopus 로고    scopus 로고
    • Metal-induced toxicity, carcinogenesis, mechanisms and cellular responses
    • Leonard SS, Bower JJ, Shi X. Metal-induced toxicity, carcinogenesis, mechanisms and cellular responses. Mol Cell Biochem 2004;255:3-10.
    • (2004) Mol Cell Biochem , vol.255 , pp. 3-10
    • Leonard, S.S.1    Bower, J.J.2    Shi, X.3
  • 74
    • 33845451723 scopus 로고    scopus 로고
    • Ros-induced histone modifications and their role in cell survival and cell death
    • Monks TJ, Xie R, Tikoo K, Lau SS. Ros-induced histone modifications and their role in cell survival and cell death. Drug Metab Rev 2006;38:755-67.
    • (2006) Drug Metab Rev , vol.38 , pp. 755-767
    • Monks, T.J.1    Xie, R.2    Tikoo, K.3    Lau, S.S.4
  • 75
    • 0037692951 scopus 로고    scopus 로고
    • Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10)
    • Donaldson K, Stone V, Borm PJ et al. Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10). Free Radic Biol Med 2003;34: 1369-82.
    • (2003) Free Radic Biol Med , vol.34 , pp. 1369-1382
    • Donaldson, K.1    Stone, V.2    Borm, P.J.3
  • 76
    • 0037372312 scopus 로고    scopus 로고
    • Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles
    • Gilmour PS, Rahman I, Donaldson K, MacNee W. Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles. Am J Physiol Lung Cell Mol Physiol 2003;284:L533-40.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284
    • Gilmour, P.S.1    Rahman, I.2    Donaldson, K.3    MacNee, W.4
  • 77
    • 43049101535 scopus 로고    scopus 로고
    • Weidhaas JB. miRNA modulation of the cellular stress response
    • Babar IA, Slack FJ, Weidhaas JB. miRNA modulation of the cellular stress response. Future Oncol 2008;4:289-98.
    • (2008) Future Oncol , vol.4 , pp. 289-298
    • Babar, I.A.1    Slack, F.J.2
  • 78
    • 9644268948 scopus 로고    scopus 로고
    • Copper-mediated oxidative DNA damage induced by eugenol: possible involvement of O-demethylation
    • Sakano K, Inagaki Y, Oikawa S, Hiraku Y, Kawanishi S. Copper-mediated oxidative DNA damage induced by eugenol: possible involvement of O-demethylation. Mutat Res 2004;565:35-44.
    • (2004) Mutat Res , vol.565 , pp. 35-44
    • Sakano, K.1    Inagaki, Y.2    Oikawa, S.3    Hiraku, Y.4    Kawanishi, S.5
  • 79
    • 44449145862 scopus 로고    scopus 로고
    • Redox signaling and cancer: the role of "labile" iron
    • Galaris D, Skiada V, Barbouti A. Redox signaling and cancer: the role of "labile" iron. Cancer Lett 2008;266: 21-29.
    • (2008) Cancer Lett , vol.266 , pp. 21-29
    • Galaris, D.1    Skiada, V.2    Barbouti, A.3
  • 80
  • 81
    • 22544437866 scopus 로고    scopus 로고
    • Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation
    • Benbrahim-Tallaa L, Waterland RA, Styblo M, Achanzar WE, Webber MM, Waalkes MP. Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation. Toxicol Appl Pharmacol 2005;206:288-98.
    • (2005) Toxicol Appl Pharmacol , vol.206 , pp. 288-298
    • Benbrahim-Tallaa, L.1    Waterland, R.A.2    Styblo, M.3    Achanzar, W.E.4    Webber, M.M.5    Waalkes, M.P.6
  • 82
    • 50349083509 scopus 로고    scopus 로고
    • Interplay between cellular methyl metabolism and adaptive efflux during oncogenic transformation from chronic arsenic exposure in human cells
    • Coppin JF, Qu W, Waalkes MP. Interplay between cellular methyl metabolism and adaptive efflux during oncogenic transformation from chronic arsenic exposure in human cells. J Biol Chem 2008;283:19342-50.
    • (2008) J Biol Chem , vol.283 , pp. 19342-19350
    • Coppin, J.F.1    Qu, W.2    Waalkes, M.P.3
  • 83
    • 0030885707 scopus 로고    scopus 로고
    • Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression
    • Zhao CQ, Young MR, Diwan BA, Coogan TP, Waalkes MP. Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression. Proc Natl Acad Sci USA 1997;94: 10907-12.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10907-10912
    • Zhao, C.Q.1    Young, M.R.2    Diwan, B.A.3    Coogan, T.P.4    Waalkes, M.P.5
  • 84
    • 4444371161 scopus 로고    scopus 로고
    • Chronic inorganic arsenic exposure induces hepatic global and individual gene hypomethylation: implications for arsenic hepatocarcinogenesis
    • Chen H, Li S, Liu J, Diwan BA, Barrett JC, Waalkes MP. Chronic inorganic arsenic exposure induces hepatic global and individual gene hypomethylation: implications for arsenic hepatocarcinogenesis. Carcinogenesis 2004;25: 1779-86.
    • (2004) Carcinogenesis , vol.25 , pp. 1779-1786
    • Chen, H.1    Li, S.2    Liu, J.3    Diwan, B.A.4    Barrett, J.C.5    Waalkes, M.P.6
  • 85
    • 0036262265 scopus 로고    scopus 로고
    • Sodium arsenite administration via drinking water increases genome-wide and Ha-ras DNA hypomethylation in methyl-deficient C57BL/6J mice
    • Okoji RS, Yu RC, Maronpot RR, Froines JR. Sodium arsenite administration via drinking water increases genome-wide and Ha-ras DNA hypomethylation in methyl-deficient C57BL/6J mice. Carcinogenesis 2002;23: 777-85.
    • (2002) Carcinogenesis , vol.23 , pp. 777-785
    • Okoji, R.S.1    Yu, R.C.2    Maronpot, R.R.3    Froines, J.R.4
  • 86
    • 18244365558 scopus 로고    scopus 로고
    • Dietary arsenic affects dimethylhydrazine-induced aberrant crypt formation and hepatic global DNA methylation and DNA methyltransferase activity in rats
    • Uthus EO, Davis C. Dietary arsenic affects dimethylhydrazine-induced aberrant crypt formation and hepatic global DNA methylation and DNA methyltransferase activity in rats. Biol Trace Elem Res 2005;103: 133-45.
    • (2005) Biol Trace Elem Res , vol.103 , pp. 133-145
    • Uthus, E.O.1    Davis, C.2
  • 87
    • 4444381916 scopus 로고    scopus 로고
    • Biokinetics and subchronic toxic effects of oral arsenite, arsenate, monomethylarsonic acid, and dimethylarsinic acid in v-Ha-ras transgenic (Tg.AC) mice
    • Xie Y, Trouba KJ, Liu J, Waalkes MP, Germolec DR. Biokinetics and subchronic toxic effects of oral arsenite, arsenate, monomethylarsonic acid, and dimethylarsinic acid in v-Ha-ras transgenic (Tg.AC) mice. Environ Health Perspect 2004;112:1255-63.
    • (2004) Environ Health Perspect , vol.112 , pp. 1255-1263
    • Xie, Y.1    Trouba, K.J.2    Liu, J.3    Waalkes, M.P.4    Germolec, D.R.5
  • 89
    • 35148901501 scopus 로고    scopus 로고
    • Genomic methylation of peripheral blood leukocyte DNA: influences of arsenic and folate in Bangladeshi adults
    • Pilsner JR, Liu X, Ahsan H et al. Genomic methylation of peripheral blood leukocyte DNA: influences of arsenic and folate in Bangladeshi adults. Am J Clin Nutr 2007; 86:1179-86.
    • (2007) Am J Clin Nutr , vol.86 , pp. 1179-1186
    • Pilsner, J.R.1    Liu, X.2    Ahsan, H.3
  • 90
    • 34547665306 scopus 로고    scopus 로고
    • Arsenic salts induced autophagic cell death and hypermethylation of DAPK promoter in SV-40 immortalized human uroepithelial cells
    • Chai CY, Huang YC, Hung WC, Kang WY, Chen WT. Arsenic salts induced autophagic cell death and hypermethylation of DAPK promoter in SV-40 immortalized human uroepithelial cells. Toxicol Lett 2007;173:48-56.
    • (2007) Toxicol Lett , vol.173 , pp. 48-56
    • Chai, C.Y.1    Huang, Y.C.2    Hung, W.C.3    Kang, W.Y.4    Chen, W.T.5
  • 91
    • 33746076034 scopus 로고    scopus 로고
    • Hypermethylation of CpG island of p16 gene and arsenic trioxide induced p16 gene demethylation in multiple myeloma
    • Fu HY, Shen JZ. Hypermethylation of CpG island of p16 gene and arsenic trioxide induced p16 gene demethylation in multiple myeloma. Zhonghua Nei Ke Za Zhi 2005; 44:411-14.
    • (2005) Zhonghua Nei Ke Za Zhi , vol.44 , pp. 411-414
    • Fu, H.Y.1    Shen, J.Z.2
  • 93
    • 0030742792 scopus 로고    scopus 로고
    • Arsenic alters cytosine methylation patterns of the promoter of the tumor suppressor gene p53 in human lung cells: a model for a mechanism of carcinogenesis
    • Mass MJ, Wang L. Arsenic alters cytosine methylation patterns of the promoter of the tumor suppressor gene p53 in human lung cells: a model for a mechanism of carcinogenesis. Mutat Res 1997;386:263-77.
    • (1997) Mutat Res , vol.386 , pp. 263-277
    • Mass, M.J.1    Wang, L.2
  • 94
    • 0035884036 scopus 로고    scopus 로고
    • Association of c-myc overexpression and hyperproliferation with arsenite-induced malignant transformation
    • Chen H, Liu J, Zhao CQ, Diwan BA, Merrick BA, Waalkes MP. Association of c-myc overexpression and hyperproliferation with arsenite-induced malignant transformation. Toxicol Appl Pharmacol 2001;175: 260-68.
    • (2001) Toxicol Appl Pharmacol , vol.175 , pp. 260-268
    • Chen, H.1    Liu, J.2    Zhao, C.Q.3    Diwan, B.A.4    Merrick, B.A.5    Waalkes, M.P.6
  • 95
    • 0036105865 scopus 로고    scopus 로고
    • Transformation by inorganic arsenic compounds of normal Syrian hamster embryo cells into a neoplastic state in which they become anchorage-independent and cause tumors in newborn hamsters
    • Takahashi M, Barrett JC, Tsutsui T. Transformation by inorganic arsenic compounds of normal Syrian hamster embryo cells into a neoplastic state in which they become anchorage-independent and cause tumors in newborn hamsters. Int J Cancer 2002;99:629-34.
    • (2002) Int J Cancer , vol.99 , pp. 629-634
    • Takahashi, M.1    Barrett, J.C.2    Tsutsui, T.3
  • 96
    • 33744827997 scopus 로고    scopus 로고
    • Chronic oral exposure to inorganic arsenate interferes with methylation status of p16INK4a and RASSF1A and induces lung cancer in A/J mice
    • Cui X, Wakai T, Shirai Y, Hatakeyama K, Hirano S. Chronic oral exposure to inorganic arsenate interferes with methylation status of p16INK4a and RASSF1A and induces lung cancer in A/J mice. Toxicol Sci 2006; 91:372-81.
    • (2006) Toxicol Sci , vol.91 , pp. 372-381
    • Cui, X.1    Wakai, T.2    Shirai, Y.3    Hatakeyama, K.4    Hirano, S.5
  • 97
    • 1642350435 scopus 로고    scopus 로고
    • Estrogen signaling in livers of male mice with hepatocellular carcinoma induced by exposure to arsenic in utero
    • Waalkes MP, Liu J, Chen H et al. Estrogen signaling in livers of male mice with hepatocellular carcinoma induced by exposure to arsenic in utero. J Natl Cancer Inst 2004;96:466-74.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 466-474
    • Waalkes, M.P.1    Liu, J.2    Chen, H.3
  • 98
    • 31144434402 scopus 로고    scopus 로고
    • DNA hypermethylation of promoter of gene p53 and p16 in arsenic-exposed people with and without malignancy
    • Chanda S, Dasgupta UB, Guhamazumder D et al. DNA hypermethylation of promoter of gene p53 and p16 in arsenic-exposed people with and without malignancy. Toxicol Sci 2006;89:431-37.
    • (2006) Toxicol Sci , vol.89 , pp. 431-437
    • Chanda, S.1    Dasgupta, U.B.2    Guhamazumder, D.3
  • 99
    • 36549053542 scopus 로고    scopus 로고
    • Urothelial carcinomas arising in arsenic-contaminated areas are associated with hypermethylation of the gene promoter of the death-associated protein kinase
    • Chen WT, Hung WC, Kang WY, Huang YC, Chai CY. Urothelial carcinomas arising in arsenic-contaminated areas are associated with hypermethylation of the gene promoter of the death-associated protein kinase. Histopathology 2007;51:785-92.
    • (2007) Histopathology , vol.51 , pp. 785-792
    • Chen, W.T.1    Hung, W.C.2    Kang, W.Y.3    Huang, Y.C.4    Chai, C.Y.5
  • 100
    • 29744460315 scopus 로고    scopus 로고
    • Carcinogen exposure and gene promoter hypermethylation in bladder cancer
    • Marsit CJ, Karagas MR, Danaee H et al. Carcinogen exposure and gene promoter hypermethylation in bladder cancer. Carcinogenesis 2006;27:112-16.
    • (2006) Carcinogenesis , vol.27 , pp. 112-116
    • Marsit, C.J.1    Karagas, M.R.2    Danaee, H.3
  • 101
    • 34247872855 scopus 로고    scopus 로고
    • Analysis of p16 gene mutation, deletion and methylation in patients with arseniasis produced by indoor unventilated-stove coal usage in Guizhou, China
    • Zhang AH, Bin HH, Pan XL, Xi XG. Analysis of p16 gene mutation, deletion and methylation in patients with arseniasis produced by indoor unventilated-stove coal usage in Guizhou, China. J Toxicol Environ Health A 2007;70:970-75.
    • (2007) J Toxicol Environ Health A , vol.70 , pp. 970-975
    • Zhang, A.H.1    Bin, H.H.2    Pan, X.L.3    Xi, X.G.4
  • 102
    • 0033950326 scopus 로고    scopus 로고
    • Expression of p53 in arsenic-related and sporadic basal cell carcinoma
    • Boonchai W, Walsh M, Cummings M, Chenevix-Trench G. Expression of p53 in arsenic-related and sporadic basal cell carcinoma. Arch Dermatol 2000;136: 195-98.
    • (2000) Arch Dermatol , vol.136 , pp. 195-198
    • Boonchai, W.1    Walsh, M.2    Cummings, M.3    Chenevix-Trench, G.4
  • 103
    • 0021100706 scopus 로고
    • Acetylation and methylation patterns of core histones are modified after heat or arsenite treatment of Drosophila tissue culture cells
    • Arrigo AP. Acetylation and methylation patterns of core histones are modified after heat or arsenite treatment of Drosophila tissue culture cells. Nucleic Acids Res 1983;11: 1389-404.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1389-1404
    • Arrigo, A.P.1
  • 104
    • 70350616210 scopus 로고    scopus 로고
    • Acetylated H4K16 by MYST1 protects UROtsa cells from arsenic toxicity and is decreased following chronic arsenic exposure
    • Jo WJ, Ren X, Chu F et al. Acetylated H4K16 by MYST1 protects UROtsa cells from arsenic toxicity and is decreased following chronic arsenic exposure. Toxicol Appl Pharmacol 2009;241:294-302.
    • (2009) Toxicol Appl Pharmacol , vol.241 , pp. 294-302
    • Jo, W.J.1    Ren, X.2    Chu, F.3
  • 105
    • 0037147333 scopus 로고    scopus 로고
    • Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells
    • Li J, Chen P, Sinogeeva N et al. Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells. J Biol Chem 2002;277:49504-10.
    • (2002) J Biol Chem , vol.277 , pp. 49504-49510
    • Li, J.1    Chen, P.2    Sinogeeva, N.3
  • 106
    • 0038376022 scopus 로고    scopus 로고
    • Tumor promoter arsenite stimulates histone H3 phosphoacetylation of proto-oncogenes c-fos and c-jun chromatin in human diploid fibroblasts
    • Li J, Gorospe M, Barnes J, Liu Y. Tumor promoter arsenite stimulates histone H3 phosphoacetylation of proto-oncogenes c-fos and c-jun chromatin in human diploid fibroblasts. J Biol Chem 2003;278: 13183-91.
    • (2003) J Biol Chem , vol.278 , pp. 13183-13191
    • Li, J.1    Gorospe, M.2    Barnes, J.3    Liu, Y.4
  • 107
    • 41149141486 scopus 로고    scopus 로고
    • Sodium arsenite modulates histone acetylation, histone deacetylase activity and HMGN protein dynamics in human cells
    • Ramirez T, Brocher J, Stopper H, Hock R. Sodium arsenite modulates histone acetylation, histone deacetylase activity and HMGN protein dynamics in human cells. Chromosoma 2008;117:147-57.
    • (2008) Chromosoma , vol.117 , pp. 147-157
    • Ramirez, T.1    Brocher, J.2    Stopper, H.3    Hock, R.4
  • 108
    • 0022553177 scopus 로고
    • Further characterization of the posttranslational modifications of core histones in response to heat and arsenite stress in Drosophila
    • Desrosiers R, Tanguay RM. Further characterization of the posttranslational modifications of core histones in response to heat and arsenite stress in Drosophila. Biochem Cell Biol 1986;64:750-57.
    • (1986) Biochem Cell Biol , vol.64 , pp. 750-757
    • Desrosiers, R.1    Tanguay, R.M.2
  • 109
    • 0023926494 scopus 로고
    • Methylation of Drosophila histones at proline, lysine, and arginine residues during heat shock
    • Desrosiers R, Tanguay RM. Methylation of Drosophila histones at proline, lysine, and arginine residues during heat shock. J Biol Chem 1988;263:4686-92.
    • (1988) J Biol Chem , vol.263 , pp. 4686-4692
    • Desrosiers, R.1    Tanguay, R.M.2
  • 111
    • 61849137246 scopus 로고    scopus 로고
    • Effects of nickel, chromate, and arsenite on histone 3 lysine methylation
    • Zhou X, Li Q, Arita A, Sun H, Costa M. Effects of nickel, chromate, and arsenite on histone 3 lysine methylation. Toxicol Appl Pharmacol 2009;236:78-84.
    • (2009) Toxicol Appl Pharmacol , vol.236 , pp. 78-84
    • Zhou, X.1    Li, Q.2    Arita, A.3    Sun, H.4    Costa, M.5
  • 112
    • 33845734139 scopus 로고    scopus 로고
    • Lymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells
    • Zykova TA, Zhu F, Lu C et al. Lymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells. Clin Cancer Res 2006;12: 6884-93.
    • (2006) Clin Cancer Res , vol.12 , pp. 6884-6893
    • Zykova, T.A.1    Zhu, F.2    Lu, C.3
  • 113
    • 33845312687 scopus 로고    scopus 로고
    • MicroRNA responses to cellular stress
    • Marsit CJ, Eddy K, Kelsey KT. MicroRNA responses to cellular stress. Cancer Res 2006;66:10843-48.
    • (2006) Cancer Res , vol.66 , pp. 10843-10848
    • Marsit, C.J.1    Eddy, K.2    Kelsey, K.T.3
  • 114
    • 70349510144 scopus 로고    scopus 로고
    • Interaction between arsenic trioxide and human primary cells: emphasis on human cells of myeloid origin
    • Binet F, Antoine F, Girard D. Interaction between arsenic trioxide and human primary cells: emphasis on human cells of myeloid origin. Inflamm Allergy Drug Targets 2009;8:21-27.
    • (2009) Inflamm Allergy Drug Targets , vol.8 , pp. 21-27
    • Binet, F.1    Antoine, F.2    Girard, D.3
  • 115
    • 78751574156 scopus 로고    scopus 로고
    • MicroRNA-dependent regulation of PTEN after arsenic trioxide treatment in bladder cancer cell line T24
    • Cao Y, Yu SL, Wang Y, Guo GY, Ding Q, An RH. MicroRNA-dependent regulation of PTEN after arsenic trioxide treatment in bladder cancer cell line T24. Tumour Biol 2011;32:179-88.
    • (2011) Tumour Biol , vol.32 , pp. 179-188
    • Cao, Y.1    Yu, S.L.2    Wang, Y.3    Guo, G.Y.4    Ding, Q.5    An, R.H.6
  • 116
    • 0028966572 scopus 로고
    • Carcinogenic nickel silences gene-expression by chromatin condensation and DNA methylation - a new model for epigenetic carcinogens
    • Lee YW, Klein CB, Kargacin B et al. Carcinogenic nickel silences gene-expression by chromatin condensation and DNA methylation - a new model for epigenetic carcinogens. Mol Cell Biol 1995;15:2547-57.
    • (1995) Mol Cell Biol , vol.15 , pp. 2547-2557
    • Lee, Y.W.1    Klein, C.B.2    Kargacin, B.3
  • 117
    • 0028966572 scopus 로고
    • Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens
    • Lee YW, Klein CB, Kargacin B et al. Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens. Mol Cell Biol 1995;15:2547-57.
    • (1995) Mol Cell Biol , vol.15 , pp. 2547-2557
    • Lee, Y.W.1    Klein, C.B.2    Kargacin, B.3
  • 118
    • 0025757211 scopus 로고
    • Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control
    • Klein CB, Conway K, Wang XW et al. Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control. Science 1991;251:796-99.
    • (1991) Science , vol.251 , pp. 796-799
    • Klein, C.B.1    Conway, K.2    Wang, X.W.3
  • 119
    • 0036248155 scopus 로고    scopus 로고
    • Reactive oxygen-induced carcinogenesis causes hypermethylation of p16(Ink4a) and activation of MAP kinase
    • Govindarajan B, Klafter R, Miller MS et al. Reactive oxygen-induced carcinogenesis causes hypermethylation of p16(Ink4a) and activation of MAP kinase. Mol Med 2002;8:1-8.
    • (2002) Mol Med , vol.8 , pp. 1-8
    • Govindarajan, B.1    Klafter, R.2    Miller, M.S.3
  • 120
    • 29644437065 scopus 로고    scopus 로고
    • Truncation, deamidation, and oxidation of histone H2B in cells cultured with nickel(II)
    • Karaczyn AA, Golebiowski F, Kasprzak KS. Truncation, deamidation, and oxidation of histone H2B in cells cultured with nickel(II). Chem Res Toxicol 2005;18: 1934-42.
    • (2005) Chem Res Toxicol , vol.18 , pp. 1934-1942
    • Karaczyn, A.A.1    Golebiowski, F.2    Kasprzak, K.S.3
  • 121
    • 33645218975 scopus 로고    scopus 로고
    • Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel
    • Karaczyn A, Ivanov S, Reynolds M, Zhitkovich A, Kasprzak KS, Salnikow K. Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel. J Cell Biochem 2006;97:1025-35.
    • (2006) J Cell Biochem , vol.97 , pp. 1025-1035
    • Karaczyn, A.1    Ivanov, S.2    Reynolds, M.3    Zhitkovich, A.4    Kasprzak, K.S.5    Salnikow, K.6
  • 123
    • 33646576501 scopus 로고    scopus 로고
    • Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing
    • Chen H, Ke Q, Kluz T, Yan Y, Costa M. Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing. Mol Cell Biol 2006;26:3728-37.
    • (2006) Mol Cell Biol , vol.26 , pp. 3728-3737
    • Chen, H.1    Ke, Q.2    Kluz, T.3    Yan, Y.4    Costa, M.5
  • 124
    • 33745603983 scopus 로고    scopus 로고
    • Alterations of histone modifications and transgene silencing by nickel chloride
    • Ke QD, Davidson T, Chen HB, Kluz T, Costa M. Alterations of histone modifications and transgene silencing by nickel chloride. Carcinogenesis 2006;27:1481-88.
    • (2006) Carcinogenesis , vol.27 , pp. 1481-1488
    • Ke, Q.D.1    Davidson, T.2    Chen, H.B.3    Kluz, T.4    Costa, M.5
  • 125
    • 30344451384 scopus 로고    scopus 로고
    • Inhibition of core histones acetylation by carcinogenic nickel(II)
    • Golebiowski F, Kasprzak KS. Inhibition of core histones acetylation by carcinogenic nickel(II). Mol Cell Biochem 2005;279:133-39.
    • (2005) Mol Cell Biochem , vol.279 , pp. 133-139
    • Golebiowski, F.1    Kasprzak, K.S.2
  • 126
    • 0030904893 scopus 로고    scopus 로고
    • DNA methylation, heterochromatin and epigenetic carcinogens
    • Klein CB, Costa M. DNA methylation, heterochromatin and epigenetic carcinogens. Mutat Res-Rev Mutat Res 1997; 386:163-80.
    • (1997) Mutat Res-Rev Mutat Res , vol.386 , pp. 163-180
    • Klein, C.B.1    Costa, M.2
  • 127
    • 0025757211 scopus 로고
    • Senescence of nickel-transformed cells by an x-chromosome - possible epigenetic control
    • Klein CB, Conway K, Wang XW et al. Senescence of nickel-transformed cells by an x-chromosome - possible epigenetic control. Science 1991;251:796-99.
    • (1991) Science , vol.251 , pp. 796-799
    • Klein, C.B.1    Conway, K.2    Wang, X.W.3
  • 128
    • 0042092322 scopus 로고    scopus 로고
    • Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure
    • Yan Y, Kluz T, Zhang P, Chen HB, Costa M. Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure. Toxicol Appl Pharmacol 2003;190:272-77.
    • (2003) Toxicol Appl Pharmacol , vol.190 , pp. 272-277
    • Yan, Y.1    Kluz, T.2    Zhang, P.3    Chen, H.B.4    Costa, M.5
  • 129
    • 0142188630 scopus 로고    scopus 로고
    • Inhibition and reversal of nickel-induced transformation by the histone deacetylase inhibitor trichostatin A
    • Zhang QW, Salnikow K, Kluz T, Chen LC, Su WC, Costa M. Inhibition and reversal of nickel-induced transformation by the histone deacetylase inhibitor trichostatin A. Toxicol Appl Pharmacol 2003;192:201-11.
    • (2003) Toxicol Appl Pharmacol , vol.192 , pp. 201-211
    • Zhang, Q.W.1    Salnikow, K.2    Kluz, T.3    Chen, L.C.4    Su, W.C.5    Costa, M.6
  • 131
    • 30344451384 scopus 로고    scopus 로고
    • Inhibition of core histones acetylation by carcinogenic nickel(II)
    • Golebiowski F, Kasprzak KS. Inhibition of core histones acetylation by carcinogenic nickel(II). Mol Cell Biochem 2005;279:133-39.
    • (2005) Mol Cell Biochem , vol.279 , pp. 133-139
    • Golebiowski, F.1    Kasprzak, K.S.2
  • 132
    • 46949090178 scopus 로고    scopus 로고
    • Nickel compounds induce phosphorylation of histone H3 at serine 10 by activating JNK-MAPK pathway
    • Ke Q, Li Q, Ellen TP, Sun H, Costa M. Nickel compounds induce phosphorylation of histone H3 at serine 10 by activating JNK-MAPK pathway. Carcinogenesis 2008;29: 1276-81.
    • (2008) Carcinogenesis , vol.29 , pp. 1276-1281
    • Ke, Q.1    Li, Q.2    Ellen, T.P.3    Sun, H.4    Costa, M.5
  • 133
    • 44149105575 scopus 로고    scopus 로고
    • Global DNA hypomethylation, rather than reactive oxygen species (ROS), a potential facilitator of cadmium-stimulated K562 cell proliferation
    • Huang D, Zhang Y, Qi Y, Chen C, Ji W. Global DNA hypomethylation, rather than reactive oxygen species (ROS), a potential facilitator of cadmium-stimulated K562 cell proliferation. Toxicol Lett 2008;179:43-47.
    • (2008) Toxicol Lett , vol.179 , pp. 43-47
    • Huang, D.1    Zhang, Y.2    Qi, Y.3    Chen, C.4    Ji, W.5
  • 134
    • 0037960155 scopus 로고    scopus 로고
    • Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation
    • Takiguchi M, Achanzar WE, Qu W, Li G, Waalkes MP. Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation. Exp Cell Res 2003;286:355-65.
    • (2003) Exp Cell Res , vol.286 , pp. 355-365
    • Takiguchi, M.1    Achanzar, W.E.2    Qu, W.3    Li, G.4    Waalkes, M.P.5
  • 135
    • 40949155180 scopus 로고    scopus 로고
    • Cadmium exposure and hypertension in the 1999-2004 National Health and Nutrition Examination Survey (NHANES)
    • Tellez-Plaza M, Navas-Acien A, Crainiceanu CM, Guallar E. Cadmium exposure and hypertension in the 1999-2004 National Health and Nutrition Examination Survey (NHANES). Environ Health Perspect 2008;116: 51-56.
    • (2008) Environ Health Perspect , vol.116 , pp. 51-56
    • Tellez-Plaza, M.1    Navas-Acien, A.2    Crainiceanu, C.M.3    Guallar, E.4
  • 136
    • 33749347262 scopus 로고    scopus 로고
    • Environmental cardiology - Studying mechanistic links between pollution and heart disease
    • Bhatnagar A. Environmental cardiology - Studying mechanistic links between pollution and heart disease. Circulation Res 2006;99:692-705.
    • (2006) Circulation Res , vol.99 , pp. 692-705
    • Bhatnagar, A.1
  • 137
    • 77953253517 scopus 로고    scopus 로고
    • Exposure to metal-rich particulate matter modifies the expression of candidate microRNAs in peripheral blood leukocytes
    • Bollati V, Marinelli B, Apostoli P et al. Exposure to metal-rich particulate matter modifies the expression of candidate microRNAs in peripheral blood leukocytes. Environ Health Perspect 2010;118:763-68.
    • (2010) Environ Health Perspect , vol.118 , pp. 763-768
    • Bollati, V.1    Marinelli, B.2    Apostoli, P.3
  • 139
    • 73949158151 scopus 로고    scopus 로고
    • Mercury-associated DNA hypomethylation in polar bear brains via the LUminometric Methylation Assay: a sensitive method to study epigenetics in wildlife
    • Pilsner JR, Lazarus AL, Nam DH et al. Mercury-associated DNA hypomethylation in polar bear brains via the LUminometric Methylation Assay: a sensitive method to study epigenetics in wildlife. Mol Ecol 2010;19:307-14.
    • (2010) Mol Ecol , vol.19 , pp. 307-314
    • Pilsner, J.R.1    Lazarus, A.L.2    Nam, D.H.3
  • 140
    • 80052599367 scopus 로고    scopus 로고
    • Epigenetic Assessment of environmental chemicals detected in maternal peripheral and cord blood samples
    • Arai Y, Ohgane J, Yagi S et al. Epigenetic Assessment of environmental chemicals detected in maternal peripheral and cord blood samples. J Reprod Dev 2011;57:507-17.
    • (2011) J Reprod Dev , vol.57 , pp. 507-517
    • Arai, Y.1    Ohgane, J.2    Yagi, S.3
  • 141
    • 77953281055 scopus 로고    scopus 로고
    • Biomarkers of lead exposure and DNA methylation within retrotransposons
    • Wright RO, Schwartz J, Wright RJ et al. Biomarkers of lead exposure and DNA methylation within retrotransposons. Environ Health Perspect 2010;118:790-95.
    • (2010) Environ Health Perspect , vol.118 , pp. 790-795
    • Wright, R.O.1    Schwartz, J.2    Wright, R.J.3
  • 142
    • 69949103740 scopus 로고    scopus 로고
    • Influence of prenatal lead exposure on genomic methylation of cord blood DNA
    • Pilsner JR, Hu H, Ettinger A et al. Influence of prenatal lead exposure on genomic methylation of cord blood DNA. Environ Health Perspect 2009;117:1466-71.
    • (2009) Environ Health Perspect , vol.117 , pp. 1466-1471
    • Pilsner, J.R.1    Hu, H.2    Ettinger, A.3
  • 143
    • 33746916117 scopus 로고    scopus 로고
    • The reduced expression and aberrant methylation of p16(INK4a) in chromate workers with lung cancer
    • Kondo K, Takahashi Y, Hirose Y et al. The reduced expression and aberrant methylation of p16(INK4a) in chromate workers with lung cancer. Lung Cancer 2006; 53:295-302.
    • (2006) Lung Cancer , vol.53 , pp. 295-302
    • Kondo, K.1    Takahashi, Y.2    Hirose, Y.3
  • 144
    • 13944261633 scopus 로고    scopus 로고
    • Microsatellite instability and protein expression of the DNA mismatch repair gene, hMLH1, of lung cancer in chromate-exposed workers
    • Takahashi Y, Kondo K, Hirose T et al. Microsatellite instability and protein expression of the DNA mismatch repair gene, hMLH1, of lung cancer in chromate-exposed workers. Mol Carcinogenesis 2005;42:150-58.
    • (2005) Mol Carcinogenesis , vol.42 , pp. 150-158
    • Takahashi, Y.1    Kondo, K.2    Hirose, T.3
  • 145
    • 77950019775 scopus 로고    scopus 로고
    • Toxic effects of various pollutants in 11B7501 lymphoma B cell line from harbour seal (Phoca vitulina)
    • Frouin H, Fortier M, Fournier M. Toxic effects of various pollutants in 11B7501 lymphoma B cell line from harbour seal (Phoca vitulina). Toxicology 2010;270:66-76.
    • (2010) Toxicology , vol.270 , pp. 66-76
    • Frouin, H.1    Fortier, M.2    Fournier, M.3
  • 146
    • 62349133722 scopus 로고    scopus 로고
    • Mechanisms of action for metallic elements and their species classified carcinogen R 45 and R 49 by EU
    • Apostoli P, Catalani S. Mechanisms of action for metallic elements and their species classified carcinogen R 45 and R 49 by EU. G Ital Med Lav Ergon 2008;30:382-91.
    • (2008) G Ital Med Lav Ergon , vol.30 , pp. 382-391
    • Apostoli, P.1    Catalani, S.2
  • 147
    • 35148832010 scopus 로고    scopus 로고
    • Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation
    • Schnekenburger M, Talaska G, Puga A. Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. Mol Cell Biol 2007;27:7089-101.
    • (2007) Mol Cell Biol , vol.27 , pp. 7089-7101
    • Schnekenburger, M.1    Talaska, G.2    Puga, A.3
  • 148
    • 67349119474 scopus 로고    scopus 로고
    • Modulation of histone methylation and MLH1 gene silencing by hexavalent chromium
    • Sun H, Zhou X, Chen H, Li Q, Costa M. Modulation of histone methylation and MLH1 gene silencing by hexavalent chromium. Toxicol Appl Pharmacol 2009;237: 258-66.
    • (2009) Toxicol Appl Pharmacol , vol.237 , pp. 258-266
    • Sun, H.1    Zhou, X.2    Chen, H.3    Li, Q.4    Costa, M.5
  • 149
    • 70350035701 scopus 로고    scopus 로고
    • Characterization of an NF-kappaB-regulated, miRNA-146a-mediated downregulation of complement factor H (CFH) in metalsulfate-stressed human brain cells
    • Pogue AI, Li YY, Cui JG et al. Characterization of an NF-kappaB-regulated, miRNA-146a-mediated downregulation of complement factor H (CFH) in metalsulfate-stressed human brain cells. J Inorg Biochem 2009;103:1591-95.
    • (2009) J Inorg Biochem , vol.103 , pp. 1591-1595
    • Pogue, A.I.1    Li, Y.Y.2    Cui, J.G.3
  • 150
    • 34548177451 scopus 로고    scopus 로고
    • Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells
    • Lukiw WJ, Pogue AI. Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells. J Inorg Biochem 2007;101: 1265-69.
    • (2007) J Inorg Biochem , vol.101 , pp. 1265-1269
    • Lukiw, W.J.1    Pogue, A.I.2
  • 151
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007;128:683-92.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 152
    • 77349107376 scopus 로고    scopus 로고
    • DNA methylation markers in colorectal cancer
    • Kim MS, Lee J, Sidransky D. DNA methylation markers in colorectal cancer. Cancer Metastasis Rev 2010;29: 181-206.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 181-206
    • Kim, M.S.1    Lee, J.2    Sidransky, D.3
  • 153
    • 72449176846 scopus 로고    scopus 로고
    • Molecular origins of cancer: Molecular basis of colorectal cancer
    • Markowitz SD, Bertagnolli MM. Molecular origins of cancer: Molecular basis of colorectal cancer. N Engl J Med 2009;361:2449-60.
    • (2009) N Engl J Med , vol.361 , pp. 2449-2460
    • Markowitz, S.D.1    Bertagnolli, M.M.2
  • 154
    • 20344385787 scopus 로고    scopus 로고
    • Epigenetic transgenerational actions of endocrine disruptors and male fertility
    • Anway MD, Cupp AS, Uzumcu M, Skinner MK. Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science 2005;308:1466-69.
    • (2005) Science , vol.308 , pp. 1466-1469
    • Anway, M.D.1    Cupp, A.S.2    Uzumcu, M.3    Skinner, M.K.4
  • 155
    • 77958534051 scopus 로고    scopus 로고
    • Epigenetic transgenerational actions of vinclozolin on promoter regions of the sperm epigenome
    • Guerrero-Bosagna C, Settles M, Lucker B, Skinner MK. Epigenetic transgenerational actions of vinclozolin on promoter regions of the sperm epigenome. PLoS One 2010;5:e13100.
    • (2010) PLoS One , vol.5
    • Guerrero-Bosagna, C.1    Settles, M.2    Lucker, B.3    Skinner, M.K.4
  • 156
    • 33646815647 scopus 로고    scopus 로고
    • Epigenetic transgenerational actions of endocrine disruptors
    • Anway MD, Skinner MK. Epigenetic transgenerational actions of endocrine disruptors. Endocrinology 2006; 147(6 Suppl):S43-49.
    • (2006) Endocrinology , vol.147 , Issue.6 SUPPL.
    • Anway, M.D.1    Skinner, M.K.2
  • 157
    • 70349313124 scopus 로고    scopus 로고
    • Fetal and neonatal exposure to the endocrine disruptor methoxychlor causes epigenetic alterations in adult ovarian genes
    • Zama AM, Uzumcu M. Fetal and neonatal exposure to the endocrine disruptor methoxychlor causes epigenetic alterations in adult ovarian genes. Endocrinology 2009; 150:4681-91.
    • (2009) Endocrinology , vol.150 , pp. 4681-4691
    • Zama, A.M.1    Uzumcu, M.2
  • 158
    • 0034308194 scopus 로고    scopus 로고
    • Hypomethylation and overexpression of c-jun and c-myc protooncogenes and increased DNA methyltransferase activity in dichloroacetic and trichloroacetic acidpromoted mouse liver tumors
    • Tao L, Yang S, Xie M, Kramer PM, Pereira MA. Hypomethylation and overexpression of c-jun and c-myc protooncogenes and increased DNA methyltransferase activity in dichloroacetic and trichloroacetic acidpromoted mouse liver tumors. Cancer Lett 2000;158: 185-93.
    • (2000) Cancer Lett , vol.158 , pp. 185-193
    • Tao, L.1    Yang, S.2    Xie, M.3    Kramer, P.M.4    Pereira, M.A.5
  • 159
    • 0034071060 scopus 로고    scopus 로고
    • Effect of trichloroethylene and its metabolites, dichloroacetic acid and trichloroacetic acid, on the methylation and expression of c-Jun and c-Myc protooncogenes in mouse liver: prevention by methionine
    • Tao L, Yang S, Xie M, Kramer PM, Pereira MA. Effect of trichloroethylene and its metabolites, dichloroacetic acid and trichloroacetic acid, on the methylation and expression of c-Jun and c-Myc protooncogenes in mouse liver: prevention by methionine. Toxicol Sci 2000;54:399-407.
    • (2000) Toxicol Sci , vol.54 , pp. 399-407
    • Tao, L.1    Yang, S.2    Xie, M.3    Kramer, P.M.4    Pereira, M.A.5
  • 162
    • 77649225956 scopus 로고    scopus 로고
    • Association of low-dose exposure to persistent organic pollutants with global DNA hypomethylation in healthy koreans
    • Kim KY, Kim DS, Lee SK et al. Association of low-dose exposure to persistent organic pollutants with global DNA hypomethylation in healthy koreans. Environ Health Perspect 2010;118:370-74.
    • (2010) Environ Health Perspect , vol.118 , pp. 370-374
    • Kim, K.Y.1    Kim, D.S.2    Lee, S.K.3
  • 163
  • 164
    • 77956083649 scopus 로고    scopus 로고
    • A review of pesticide exposure and cancer incidence in the Agricultural Health Study cohort
    • Weichenthal S, Moase C, Chan P. A review of pesticide exposure and cancer incidence in the Agricultural Health Study cohort. Environ Health Perspect 2010;118: 1117-25.
    • (2010) Environ Health Perspect , vol.118 , pp. 1117-1125
    • Weichenthal, S.1    Moase, C.2    Chan, P.3
  • 165
    • 34548489870 scopus 로고    scopus 로고
    • Carcinogenicity of agricultural pesticides in adults and children
    • Alavanja MC, Ward MH, Reynolds P. Carcinogenicity of agricultural pesticides in adults and children. J Agromedicine 2007;12:39-56.
    • (2007) J Agromedicine , vol.12 , pp. 39-56
    • Alavanja, M.C.1    Ward, M.H.2    Reynolds, P.3
  • 167
    • 78649680573 scopus 로고    scopus 로고
    • An update of cancer incidence in the Agricultural Health Study
    • Koutros S, Alavanja MC, Lubin JH et al. An update of cancer incidence in the Agricultural Health Study. J Occup Environ Med 2010;52:1098-105.
    • (2010) J Occup Environ Med , vol.52 , pp. 1098-1105
    • Koutros, S.1    Alavanja, M.C.2    Lubin, J.H.3
  • 169
    • 77950241704 scopus 로고    scopus 로고
    • Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration
    • Song C, Kanthasamy A, Anantharam V, Sun F, Kanthasamy AG. Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration. Mol Pharmacol 2010; 77:621-32.
    • (2010) Mol Pharmacol , vol.77 , pp. 621-632
    • Song, C.1    Kanthasamy, A.2    Anantharam, V.3    Sun, F.4    Kanthasamy, A.G.5
  • 170
    • 77950241704 scopus 로고    scopus 로고
    • Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration
    • Song C, Kanthasamy A, Anantharam V, Sun F, Kanthasamy AG. Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration. Mol Pharmacol 2010; 77:621-32.
    • (2010) Mol Pharmacol , vol.77 , pp. 621-632
    • Song, C.1    Kanthasamy, A.2    Anantharam, V.3    Sun, F.4    Kanthasamy, A.G.5
  • 171
    • 41949116103 scopus 로고    scopus 로고
    • Cardiac autonomic dysfunction - effects from particulate air pollution and protection by dietary methyl nutrients and metabolic polymorphisms
    • Baccarelli A, Cassano PA, Litonjua A et al. Cardiac autonomic dysfunction - effects from particulate air pollution and protection by dietary methyl nutrients and metabolic polymorphisms. Circulation 2008;117: 1802-09.
    • (2008) Circulation , vol.117 , pp. 1802-1809
    • Baccarelli, A.1    Cassano, P.A.2    Litonjua, A.3
  • 172
    • 74949132184 scopus 로고    scopus 로고
    • Disruption of microRNA expression in human airway cells by diesel exhaust particles is linked to tumorigenesis-associated pathways
    • Jardim MJ, Fry RC, Jaspers I, Dailey L, Diaz-Sanchez D. Disruption of microRNA expression in human airway cells by diesel exhaust particles is linked to tumorigenesis-associated pathways. Environ Health Perspect 2009;117:1745-51.
    • (2009) Environ Health Perspect , vol.117 , pp. 1745-1751
    • Jardim, M.J.1    Fry, R.C.2    Jaspers, I.3    Dailey, L.4    Diaz-Sanchez, D.5
  • 173
    • 60749124259 scopus 로고    scopus 로고
    • Effects of particulate matter on genomic DNA methylation content and iNOS promoter methylation
    • Tarantini L, Bonzini M, Apostoli P et al. Effects of particulate matter on genomic DNA methylation content and iNOS promoter methylation. Environ Health Perspect 2009;117:217-22.
    • (2009) Environ Health Perspect , vol.117 , pp. 217-222
    • Tarantini, L.1    Bonzini, M.2    Apostoli, P.3
  • 174
    • 38649121719 scopus 로고    scopus 로고
    • Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location
    • Yauk C, Polyzos A, Rowan-Carroll A et al. Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location. Proc Natl Acad Sci USA 2008;105: 605-10.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 605-610
    • Yauk, C.1    Polyzos, A.2    Rowan-Carroll, A.3
  • 175
    • 39449123898 scopus 로고    scopus 로고
    • Combined inhaled diesel exhaust particles and allergen exposure alter methylation of T helper genes and IgE production in vivo
    • Liu J, Ballaney M, Al-alem U et al. Combined inhaled diesel exhaust particles and allergen exposure alter methylation of T helper genes and IgE production in vivo. Toxicol Sci 2008;102:76-81.
    • (2008) Toxicol Sci , vol.102 , pp. 76-81
    • Liu, J.1    Ballaney, M.2    Al-alem, U.3
  • 176
    • 84862008174 scopus 로고    scopus 로고
    • Relation of DNA methylation of 5′-CpG island of ACSL3 to transplacental exposure to airborne polycyclic aromatic hydrocarbons and childhood asthma
    • Perera F, Tang WY, Herbstman J et al. Relation of DNA methylation of 5′-CpG island of ACSL3 to transplacental exposure to airborne polycyclic aromatic hydrocarbons and childhood asthma. PLoS One 2009;4:e4488.
    • (2009) PLoS One , vol.4
    • Perera, F.1    Tang, W.Y.2    Herbstman, J.3
  • 177
    • 79960033306 scopus 로고    scopus 로고
    • Effects of Inhalable Metal-rich Air Particles on Histone H3K4 Dimethylation and H3K9 Acetylation in a Cross-sectional Study of Steel Workers
    • Cantone L, Nordio F, Hou L et al. Effects of Inhalable Metal-rich Air Particles on Histone H3K4 Dimethylation and H3K9 Acetylation in a Cross-sectional Study of Steel Workers. Environ Health Perspect 2011;119:964-9.
    • (2011) Environ Health Perspect , vol.119 , pp. 964-969
    • Cantone, L.1    Nordio, F.2    Hou, L.3
  • 178
    • 77953253517 scopus 로고    scopus 로고
    • Exposure to metal-rich particulate matter modifies the expression of candidate micrornas in peripheral blood leukocytes
    • Bollati V, Marinelli B, Apostoli P et al. Exposure to metal-rich particulate matter modifies the expression of candidate micrornas in peripheral blood leukocytes. Environ Health Perspect 2010.
    • (2010) Environ Health Perspect
    • Bollati, V.1    Marinelli, B.2    Apostoli, P.3
  • 179
    • 77952720805 scopus 로고    scopus 로고
    • Advances in understanding benzene health effects and susceptibility
    • 2 p following 148
    • Smith MT. Advances in understanding benzene health effects and susceptibility. Annu Rev Public Health 2010; 31:133-48 2 p following 148.
    • (2010) Annu Rev Public Health , vol.31 , pp. 133-148
    • Smith, M.T.1
  • 180
    • 0036896644 scopus 로고    scopus 로고
    • Benzene exposure and hematopoietic mortality: a long-term epidemiologic risk assessment
    • Rinsky RA, Hornung RW, Silver SR, Tseng CY. Benzene exposure and hematopoietic mortality: a long-term epidemiologic risk assessment. Am J Ind Med 2002;42: 474-80.
    • (2002) Am J Ind Med , vol.42 , pp. 474-480
    • Rinsky, R.A.1    Hornung, R.W.2    Silver, S.R.3    Tseng, C.Y.4
  • 181
    • 0024041791 scopus 로고
    • Benzene toxicity
    • Goldstein BD. Benzene toxicity. Occup Med 1988;3: 541-54.
    • (1988) Occup Med , vol.3 , pp. 541-554
    • Goldstein, B.D.1
  • 182
    • 58849161325 scopus 로고    scopus 로고
    • Childhood lymphohematopoietic cancer incidence and hazardous air pollutants in southeast Texas, 1995-2004
    • Whitworth KW, Symanski E, Coker AL. Childhood lymphohematopoietic cancer incidence and hazardous air pollutants in southeast Texas, 1995-2004. Environ Health Perspect 2008;116:1576-80.
    • (2008) Environ Health. Perspect , vol.116 , pp. 1576-1580
    • Whitworth, K.W.1    Symanski, E.2    Coker, A.L.3
  • 183
    • 0023493097 scopus 로고
    • Overall evaluations of carcinogenicity: an updating of IARC Monographs volumes 1 to 42
    • Overall evaluations of carcinogenicity: an updating of IARC Monographs volumes 1 to 42. IARC Monogr Eval Carcinog Risks Hum Suppl 1987;7:1-440.
    • (1987) IARC Monogr Eval Carcinog Risks Hum Suppl , vol.7 , pp. 1-440
  • 184
    • 40849097633 scopus 로고    scopus 로고
    • Temporal variation in the association between benzene and leukemia mortality
    • Richardson DB. Temporal variation in the association between benzene and leukemia mortality. Environ Health Perspect 2008;116:370-74.
    • (2008) Environ Health Perspect , vol.116 , pp. 370-374
    • Richardson, D.B.1
  • 185
    • 84863354627 scopus 로고    scopus 로고
    • CDC. Facts About Benzene
    • CDC. Facts About Benzene. 2005. Available from: http://www.bt.cdc.gov/agent/benzene/basics/facts.asp.
    • (2005)
  • 186
    • 33847026146 scopus 로고    scopus 로고
    • Changes in DNA methylation patterns in subjects exposed to low-dose benzene
    • Bollati V, Baccarelli A, Hou L et al. Changes in DNA methylation patterns in subjects exposed to low-dose benzene. Cancer Res 2007;67:876-80.
    • (2007) Cancer Res , vol.67 , pp. 876-880
    • Bollati, V.1    Baccarelli, A.2    Hou, L.3
  • 187
    • 77952426255 scopus 로고    scopus 로고
    • A comparison of the cytogenetic alterations and global DNA hypomethylation induced by the benzene metabolite, hydroquinone, with those induced by melphalan and etoposide
    • Ji Z, Zhang L, Peng V, Ren X, McHale CM, Smith MT. A comparison of the cytogenetic alterations and global DNA hypomethylation induced by the benzene metabolite, hydroquinone, with those induced by melphalan and etoposide. Leukemia 2010;24:986-91.
    • (2010) Leukemia , vol.24 , pp. 986-991
    • Ji, Z.1    Zhang, L.2    Peng, V.3    Ren, X.4    McHale, C.M.5    Smith, M.T.6
  • 188
    • 77952543132 scopus 로고    scopus 로고
    • Methylation of PARP-1 promoter involved in the regulation of benzene-induced decrease of PARP-1 mRNA expression
    • Gao A, Zuo X, Liu Q, Lu X, Guo W, Tian L. Methylation of PARP-1 promoter involved in the regulation of benzene-induced decrease of PARP-1 mRNA expression. Toxicol Lett 2010;195:114-18.
    • (2010) Toxicol Lett , vol.195 , pp. 114-118
    • Gao, A.1    Zuo, X.2    Liu, Q.3    Lu, X.4    Guo, W.5    Tian, L.6
  • 190
    • 33745246032 scopus 로고    scopus 로고
    • Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4
    • Ho SM, Tang WY, de Frausto JB, Prins GS. Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4. Cancer Res 2006;66:5624-32.
    • (2006) Cancer Res , vol.66 , pp. 5624-5632
    • Ho, S.M.1    Tang, W.Y.2    de Frausto, J.B.3    Prins, G.S.4
  • 191
    • 23844545162 scopus 로고    scopus 로고
    • An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment
    • vom Saal FS, Hughes C. An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment. Environ Health Perspect 2005;113:926-33.
    • (2005) Environ Health Perspect , vol.113 , pp. 926-933
    • vom Saal, F.S.1    Hughes, C.2
  • 192
    • 34548715144 scopus 로고    scopus 로고
    • Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development
    • Dolinoy DC, Huang D, Jirtle RL. Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc Natl Acad Sci USA 2007;104:13056-61.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 13056-13061
    • Dolinoy, D.C.1    Huang, D.2    Jirtle, R.L.3
  • 193
    • 58549110426 scopus 로고    scopus 로고
    • Is epigenetics an important link between early life events and adult disease?
    • Waterland RA. Is epigenetics an important link between early life events and adult disease? Horm Res 2009; 71(Suppl 1):13-16.
    • (2009) Horm Res , vol.71 , Issue.SUPPL. 1 , pp. 13-16
    • Waterland, R.A.1
  • 194
    • 77953090055 scopus 로고    scopus 로고
    • Bisphenol-A exposure in utero leads to epigenetic alterations in the developmental programming of uterine estrogen response
    • Bromer JG, Zhou Y, Taylor MB, Doherty L, Taylor HS. Bisphenol-A exposure in utero leads to epigenetic alterations in the developmental programming of uterine estrogen response. FASEB J 2010;24:2273-80.
    • (2010) FASEB J , vol.24 , pp. 2273-2280
    • Bromer, J.G.1    Zhou, Y.2    Taylor, M.B.3    Doherty, L.4    Taylor, H.S.5
  • 195
    • 77956900493 scopus 로고    scopus 로고
    • Epigenetic influences of low-dose bisphenol A in primary human breast epithelial cells
    • Weng YI, Hsu PY, Liyanarachchi S et al. Epigenetic influences of low-dose bisphenol A in primary human breast epithelial cells. Toxicol Appl Pharmacol 2010;248: 111-21.
    • (2010) Toxicol Appl Pharmacol , vol.248 , pp. 111-121
    • Weng, Y.I.1    Hsu, P.Y.2    Liyanarachchi, S.3
  • 196
    • 77953540644 scopus 로고    scopus 로고
    • Bisphenol A exposure leads to specific microRNA alterations in placental cells
    • Avissar-Whiting M, Veiga KR, Uhl KM et al. Bisphenol A exposure leads to specific microRNA alterations in placental cells. Reprod Toxicol 2010;29:401-06.
    • (2010) Reprod Toxicol , vol.29 , pp. 401-406
    • Avissar-Whiting, M.1    Veiga, K.R.2    Uhl, K.M.3
  • 197
    • 77957242787 scopus 로고    scopus 로고
    • Role of epigenetic mechanisms in differential regulation of the dioxin-inducible human CYP1A1 and CYP1B1 genes
    • Beedanagari SR, Taylor RT, Bui P, Wang F, Nickerson DW, Hankinson O. Role of epigenetic mechanisms in differential regulation of the dioxin-inducible human CYP1A1 and CYP1B1 genes. Mol Pharmacol 2010; 78:608-16.
    • (2010) Mol Pharmacol , vol.78 , pp. 608-616
    • Beedanagari, S.R.1    Taylor, R.T.2    Bui, P.3    Wang, F.4    Nickerson, D.W.5    Hankinson, O.6
  • 198
    • 34247268554 scopus 로고    scopus 로고
    • The role of insulin-like growth factor-2 gene differentially methylated regions in TCDD-induced malformation
    • Wang J, Zhao YY, Liu H et al. The role of insulin-like growth factor-2 gene differentially methylated regions in TCDD-induced malformation. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2007;24:162-66.
    • (2007) Zhonghua Yi Xue Yi Chuan Xue Za Zhi , vol.24 , pp. 162-166
    • Wang, J.1    Zhao, Y.Y.2    Liu, H.3
  • 199
    • 79953096181 scopus 로고    scopus 로고
    • Changes in DNA methylation and gene expression during 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced suppression of the lipopolysaccharide (LPS)-stimulated IgM response in splenocytes
    • McClure EA, North CM, Kaminski NE, Goodman JI. Changes in DNA methylation and gene expression during 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced suppression of the lipopolysaccharide (LPS)-stimulated IgM response in splenocytes. Toxicol Sci 2011;120:339-48.
    • (2011) Toxicol Sci , vol.120 , pp. 339-348
    • McClure, E.A.1    North, C.M.2    Kaminski, N.E.3    Goodman, J.I.4
  • 200
    • 78049261423 scopus 로고    scopus 로고
    • hsa-miR-191 is a candidate oncogene target for hepatocellular carcinoma therapy
    • Elyakim E, Sitbon E, Faerman A et al. hsa-miR-191 is a candidate oncogene target for hepatocellular carcinoma therapy. Cancer Res 2010;70:8077-87.
    • (2010) Cancer Res , vol.70 , pp. 8077-8087
    • Elyakim, E.1    Sitbon, E.2    Faerman, A.3
  • 201
    • 0036570152 scopus 로고    scopus 로고
    • Use of liquid chromatography/tandem mass spectrometry to detect distinctive indicators of in situ RDX transformation in contaminated groundwater
    • Beller HR, Tiemeier K. Use of liquid chromatography/tandem mass spectrometry to detect distinctive indicators of in situ RDX transformation in contaminated groundwater. Environ Sci Techno 2002;36:2060-66.
    • (2002) Environ Sci Techno , vol.36 , pp. 2060-2066
    • Beller, H.R.1    Tiemeier, K.2
  • 202
    • 60749122411 scopus 로고    scopus 로고
    • RDX induces aberrant expression of microRNAs in mouse brain and liver
    • Zhang B, Pan X. RDX induces aberrant expression of microRNAs in mouse brain and liver. Environ Health Perspect 2009;117:231-40.
    • (2009) Environ Health Perspect , vol.117 , pp. 231-240
    • Zhang, B.1    Pan, X.2
  • 203
    • 0036781072 scopus 로고    scopus 로고
    • DES exposure and the aging woman: mothers and daughters
    • Laitman CJ. DES exposure and the aging woman: mothers and daughters. Curr Womens Health Rep 2002;2: 390-93.
    • (2002) Curr Womens Health Rep , vol.2 , pp. 390-393
    • Laitman, C.J.1
  • 204
    • 0036799616 scopus 로고    scopus 로고
    • Risk of breast cancer in women exposed to diethylstilbestrol in utero: prelimiinary results (United States)
    • Palmer JR, Hatch EE, Rosenberg CL et al. Risk of breast cancer in women exposed to diethylstilbestrol in utero: prelimiinary results (United States). Cancer Causes Control 2002;13:753-58.
    • (2002) Cancer Causes Control , vol.13 , pp. 753-758
    • Palmer, J.R.1    Hatch, E.E.2    Rosenberg, C.L.3
  • 205
    • 67651006246 scopus 로고    scopus 로고
    • Xenoestrogeninduced epigenetic repression of microRNA-9-3 in breast epithelial cells
    • Hsu PY, Deatherage DE, Rodriguez BA et al. Xenoestrogeninduced epigenetic repression of microRNA-9-3 in breast epithelial cells. Cancer Res 2009;69:5936-45.
    • (2009) Cancer Res , vol.69 , pp. 5936-5945
    • Hsu, P.Y.1    Deatherage, D.E.2    Rodriguez, B.A.3
  • 206
    • 0024407446 scopus 로고
    • Increased methylation of chloroform extractable products and CTP: cholinephosphate cytidylyltransferase in brain membrane preparations from triethyltin-intoxicated rats
    • Mages F, Macovschi O, Prigent AF, Fonlupt P. Increased methylation of chloroform extractable products and CTP: cholinephosphate cytidylyltransferase in brain membrane preparations from triethyltin-intoxicated rats. Pharmacol Toxicol 1989;65:302-05.
    • (1989) Pharmacol Toxicol , vol.65 , pp. 302-305
    • Mages, F.1    Macovschi, O.2    Prigent, A.F.3    Fonlupt, P.4
  • 207
    • 0034812592 scopus 로고    scopus 로고
    • Effect of chloroform on dichloroacetic acid and trichloroacetic acid-induced hypomethylation and expression of the c-myc gene and on their promotion of liver and kidney tumors in mice
    • Pereira MA, Kramer PM, Conran PB, Tao L. Effect of chloroform on dichloroacetic acid and trichloroacetic acid-induced hypomethylation and expression of the c-myc gene and on their promotion of liver and kidney tumors in mice. Carcinogenesis 2001;22:1511-19.
    • (2001) Carcinogenesis , vol.22 , pp. 1511-1519
    • Pereira, M.A.1    Kramer, P.M.2    Conran, P.B.3    Tao, L.4
  • 208
    • 0034517991 scopus 로고    scopus 로고
    • Effect of trihalomethanes on cell proliferation and DNA methylation in female B6C3F1 mouse liver
    • Coffin JC, Ge R, Yang S, Kramer PM, Tao L, Pereira MA. Effect of trihalomethanes on cell proliferation and DNA methylation in female B6C3F1 mouse liver. Toxicol Sci 2000;58:243-52.
    • (2000) Toxicol Sci , vol.58 , pp. 243-252
    • Coffin, J.C.1    Ge, R.2    Yang, S.3    Kramer, P.M.4    Tao, L.5    Pereira, M.A.6
  • 209
    • 0026297648 scopus 로고
    • Chlorinated drinking-water
    • Chlorinated drinking-water. IARC Monogr Eval Carcinog Risks Hum 1991;52:45-141.
    • (1991) IARC Monogr Eval Carcinog Risks Hum , vol.52 , pp. 45-141
  • 210
    • 0020831190 scopus 로고
    • Chlorinated acids and chloral in drinking water
    • Uden PC, Miller JW. Chlorinated acids and chloral in drinking water. J Am Water Works Assoc 1983;75:524-27.
    • (1983) J Am Water Works Assoc , vol.75 , pp. 524-527
    • Uden, P.C.1    Miller, J.W.2
  • 211
    • 0021493652 scopus 로고
    • Gas chromatography/mass spectroscopy analysis of mutagenic extracts of aqueous chlorinated humic acid A comparison of the by-products to drinking water contaminants Environ
    • Coleman WE, Munch JW, Kaylor WH, Streicher RP, Ringhand HP, Meier JR. Gas chromatography/mass spectroscopy analysis of mutagenic extracts of aqueous chlorinated humic acid. A comparison of the by-products to drinking water contaminants Environ. Sci. Technol. 1984;18:674-78.
    • (1984) Sci. Technol. , vol.18 , pp. 674-678
    • Coleman, W.E.1    Munch, J.W.2    Kaylor, W.H.3    Streicher, R.P.4    Ringhand, H.P.5    Meier, J.R.6
  • 212
    • 67650083483 scopus 로고    scopus 로고
    • Epigenetic regulation in mammalian preimplantation embryo development
    • Shi L, Wu J. Epigenetic regulation in mammalian preimplantation embryo development. Reprod Biol Endocrinol 2009;7:59-69.
    • (2009) Reprod Biol Endocrinol , vol.7 , pp. 59-69
    • Shi, L.1    Wu, J.2
  • 214
    • 55949137722 scopus 로고    scopus 로고
    • Persistent epigenetic differences associated with prenatal exposure to famine in humans
    • Heijmans BT, Tobi EW, Stein AD et al. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci USA 2008;105: 17046-49.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 17046-17049
    • Heijmans, B.T.1    Tobi, E.W.2    Stein, A.D.3
  • 215
    • 70349999407 scopus 로고    scopus 로고
    • DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific
    • Tobi EW, Lumey LH, Talens RP et al. DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Hum Mol Genet 2009;18:4046-53.
    • (2009) Hum Mol Genet , vol.18 , pp. 4046-4053
    • Tobi, E.W.1    Lumey, L.H.2    Talens, R.P.3
  • 217
    • 53349145630 scopus 로고    scopus 로고
    • Genomic DNA methylation among women in a multiethnic New York City birth cohort
    • Terry MB, Ferris JS, Pilsner R et al. Genomic DNA methylation among women in a multiethnic New York City birth cohort. Cancer Epidemiol Biomarkers Prev 2008; 17:2306-10.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 2306-2310
    • Terry, M.B.1    Ferris, J.S.2    Pilsner, R.3
  • 219
    • 77957373808 scopus 로고    scopus 로고
    • Global DNA hypomethylation is associated with in utero exposure to cotinine and perfluorinated alkyl compounds
    • Guerrero-Preston R, Goldman LR, Brebi-Mieville P et al. Global DNA hypomethylation is associated with in utero exposure to cotinine and perfluorinated alkyl compounds. Epigenetics 2010;5:539-46.
    • (2010) Epigenetics , vol.5 , pp. 539-546
    • Guerrero-Preston, R.1    Goldman, L.R.2    Brebi-Mieville, P.3
  • 220
    • 78449244510 scopus 로고    scopus 로고
    • Maternal cigarette smoking during pregnancy is associated with downregulation of miR-16, miR-21, and miR-146a in the placenta
    • Maccani MA, Avissar-Whiting M, Banister CE, McGonnigal B, Padbury JF, Marsit CJ. Maternal cigarette smoking during pregnancy is associated with downregulation of miR-16, miR-21, and miR-146a in the placenta. Epigenetics 2010;5:583-89.
    • (2010) Epigenetics , vol.5 , pp. 583-589
    • Maccani, M.A.1    Avissar-Whiting, M.2    Banister, C.E.3    McGonnigal, B.4    Padbury, J.F.5    Marsit, C.J.6
  • 221
    • 70349240823 scopus 로고    scopus 로고
    • Analysis of epigenetic alterations to chromatin during development
    • Minard ME, Jain AK, Barton MC. Analysis of epigenetic alterations to chromatin during development. Genesis 2009;47:559-72.
    • (2009) Genesis , vol.47 , pp. 559-572
    • Minard, M.E.1    Jain, A.K.2    Barton, M.C.3
  • 222
    • 78149381194 scopus 로고    scopus 로고
    • Davey Smith G. Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment
    • Relton CL, Davey Smith G. Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment. PLoS Med 2010;7:e1000356.
    • (2010) PLoS Med , vol.7
    • Relton, C.L.1
  • 223
    • 79958040723 scopus 로고    scopus 로고
    • Assessing causal relationships in genomics: From Bradford-Hill criteria to complex gene-environment interactions and directed acyclic graphs
    • Geneletti S, Gallo V, Porta M, Khoury MJ, Vineis P. Assessing causal relationships in genomics: From Bradford-Hill criteria to complex gene-environment interactions and directed acyclic graphs. Emerg Themes Epidemiol 2011;8:5-22.
    • (2011) Emerg Themes Epidemiol , vol.8 , pp. 5-22
    • Geneletti, S.1    Gallo, V.2    Porta, M.3    Khoury, M.J.4    Vineis, P.5
  • 224
    • 24344466882 scopus 로고    scopus 로고
    • DNA methylation and histone modifications: teaming up to silence genes
    • Fuks F. DNA methylation and histone modifications: teaming up to silence genes. Curr Opin Genet Dev 2005; 15:490-95.
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 490-495
    • Fuks, F.1
  • 225
    • 34247540446 scopus 로고    scopus 로고
    • Epigenetics and microRNAs
    • Chuang JC, Jones PA. Epigenetics and microRNAs. Pediatr Res 2007;61(5 Pt 2):24R-29R.
    • (2007) Pediatr Res , vol.61 , Issue.5 PART 2
    • Chuang, J.C.1    Jones, P.A.2
  • 226
    • 1542399123 scopus 로고    scopus 로고
    • Arsenic-induced DNA hypomethylation affects chromosomal instability in mammalian cells
    • Sciandrello G, Caradonna F, Mauro M, Barbata G. Arsenic-induced DNA hypomethylation affects chromosomal instability in mammalian cells. Carcinogenesis 2004; 25:413-17.
    • (2004) Carcinogenesis , vol.25 , pp. 413-417
    • Sciandrello, G.1    Caradonna, F.2    Mauro, M.3    Barbata, G.4
  • 227
    • 34548671396 scopus 로고    scopus 로고
    • DNA global hypomethylation in squamous cell head and neck cancer associated with smoking, alcohol consumption and stage
    • Smith IM, Mydlarz WK, Mithani SK, Califano JA. DNA global hypomethylation in squamous cell head and neck cancer associated with smoking, alcohol consumption and stage. Int J Cancer 2007;121:1724-28.
    • (2007) Int J Cancer , vol.121 , pp. 1724-1728
    • Smith, I.M.1    Mydlarz, W.K.2    Mithani, S.K.3    Califano, J.A.4
  • 228
    • 33745125112 scopus 로고    scopus 로고
    • Promoter hypermethylation and global hypomethylation are independent epigenetic events in lymphoid leukemogenesis with opposing effects on clinical outcome
    • Roman-Gomez J, Jimenez-Velasco A, Agirre X et al. Promoter hypermethylation and global hypomethylation are independent epigenetic events in lymphoid leukemogenesis with opposing effects on clinical outcome. Leukemia 2006;20:1445-48.
    • (2006) Leukemia , vol.20 , pp. 1445-1448
    • Roman-Gomez, J.1    Jimenez-Velasco, A.2    Agirre, X.3
  • 229
    • 33646419009 scopus 로고    scopus 로고
    • Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer
    • Deng G, Nguyen A, Tanaka H et al. Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. Int J Cancer 2006;118: 2999-3005.
    • (2006) Int J Cancer , vol.118 , pp. 2999-3005
    • Deng, G.1    Nguyen, A.2    Tanaka, H.3
  • 230
    • 10044239471 scopus 로고    scopus 로고
    • Global hypomethylation is common in prostate cancer cells: a quantitative predictor for clinical outcome?
    • Brothman AR, Swanson G, Maxwell TM et al. Global hypomethylation is common in prostate cancer cells: a quantitative predictor for clinical outcome? Cancer Genet Cytogenet 2005;156:31-36.
    • (2005) Cancer Genet Cytogenet , vol.156 , pp. 31-36
    • Brothman, A.R.1    Swanson, G.2    Maxwell, T.M.3
  • 231
    • 34548130797 scopus 로고    scopus 로고
    • Global hypomethylation of peripheral leukocyte DNA in male patients with schizophrenia: a potential link between epigenetics and schizophrenia
    • Shimabukuro M, Sasaki T, Imamura A et al. Global hypomethylation of peripheral leukocyte DNA in male patients with schizophrenia: a potential link between epigenetics and schizophrenia. J Psychiatr Res 2007;41: 1042-46.
    • (2007) J Psychiatr Res , vol.41 , pp. 1042-1046
    • Shimabukuro, M.1    Sasaki, T.2    Imamura, A.3
  • 232
    • 35548937284 scopus 로고    scopus 로고
    • Oxidative stress and antioxidant defenses in goldfish liver in response to short-term exposure to arsenite
    • Bagnyukova TV, Luzhna LI, Pogribny IP, Lushchak VI. Oxidative stress and antioxidant defenses in goldfish liver in response to short-term exposure to arsenite. Environ Mol Mutagen 2007;48:658-65.
    • (2007) Environ Mol Mutagen , vol.48 , pp. 658-665
    • Bagnyukova, T.V.1    Luzhna, L.I.2    Pogribny, I.P.3    Lushchak, V.I.4
  • 233
    • 60749136375 scopus 로고    scopus 로고
    • Folate deficiency, hyperhomocysteinemia, low urinary creatinine, and hypomethylation of leukocyte DNA are risk factors for arsenic-induced skin lesions
    • Pilsner JR, Liu X, Ahsan H et al. Folate deficiency, hyperhomocysteinemia, low urinary creatinine, and hypomethylation of leukocyte DNA are risk factors for arsenic-induced skin lesions. Environ Health Perspect 2009;117:254-60.
    • (2009) Environ Health Perspect , vol.117 , pp. 254-260
    • Pilsner, J.R.1    Liu, X.2    Ahsan, H.3
  • 234
    • 44349137412 scopus 로고    scopus 로고
    • SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-20 deoxycytidine to increase SPARC expression and improve therapy response
    • Cheetham S, Tang MJ, Mesak F, Kennecke H, Owen D, Tai IT. SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-20 deoxycytidine to increase SPARC expression and improve therapy response. British J Cancer 2008;98:1810-19.
    • (2008) British J Cancer , vol.98 , pp. 1810-1819
    • Cheetham, S.1    Tang, M.J.2    Mesak, F.3    Kennecke, H.4    Owen, D.5    Tai, I.T.6
  • 235
    • 50249188284 scopus 로고    scopus 로고
    • Redundant DNA methylation in colorectal cancers of Lynch-syndrome patients
    • Alemayehu A, Sebova K, Fridrichova I. Redundant DNA methylation in colorectal cancers of Lynch-syndrome patients. Genes Chrom Cancer 2008;47:906-14.
    • (2008) Genes Chrom Cancer , vol.47 , pp. 906-914
    • Alemayehu, A.1    Sebova, K.2    Fridrichova, I.3
  • 237
    • 72949116176 scopus 로고    scopus 로고
    • Prognostic role of global DNA-methylation and histone acetylation in pT1a clear cell renal carcinoma in partial nephrectomy specimens
    • Minardi D, Lucarini G, Filosa A et al. Prognostic role of global DNA-methylation and histone acetylation in pT1a clear cell renal carcinoma in partial nephrectomy specimens. J Cell Mol Med 2009;13:2115-21.
    • (2009) J Cell Mol Med , vol.13 , pp. 2115-2121
    • Minardi, D.1    Lucarini, G.2    Filosa, A.3
  • 238
    • 77954721993 scopus 로고    scopus 로고
    • Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting
    • Schafer E, Irizarry R, Negi S et al. Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting. Blood 2010;115: 4798-809.
    • (2010) Blood , vol.115 , pp. 4798-4809
    • Schafer, E.1    Irizarry, R.2    Negi, S.3
  • 239
    • 77955473071 scopus 로고    scopus 로고
    • Low frequency of epigenetic events in urothelial tumors in young patients
    • Owen HC, Giedl J, Wild PJ et al. Low frequency of epigenetic events in urothelial tumors in young patients. J Urol 2010;184:459-63.
    • (2010) J Urol , vol.184 , pp. 459-463
    • Owen, H.C.1    Giedl, J.2    Wild, P.J.3
  • 240
    • 80053472935 scopus 로고    scopus 로고
    • Alteration of methylation status of death-associated protein kinase (dapk) gene promoter in patients with acute myeloid leukemia
    • Qian J, Yao DM, Lin J et al. Alteration of methylation status of death-associated protein kinase (dapk) gene promoter in patients with acute myeloid leukemia. Zhongguo Shi Yan Xue Ye Xue Za Zhi 2010;18: 1390-94.
    • (2010) Zhongguo Shi Yan Xue Ye Xue Za Zhi , vol.18 , pp. 1390-1394
    • Qian, J.1    Yao, D.M.2    Lin, J.3
  • 241
    • 78650235580 scopus 로고    scopus 로고
    • DNA content and methylation of p16, DAPK and RASSF1A gene in tumour and distant, normal mucosal tissue of head and neck squamous cell carcinoma patients
    • Laytragoon-Lewin N, Chen F, Castro J et al. DNA content and methylation of p16, DAPK and RASSF1A gene in tumour and distant, normal mucosal tissue of head and neck squamous cell carcinoma patients. Anticancer Res 2010;30:4643-48.
    • (2010) Anticancer Res , vol.30 , pp. 4643-4648
    • Laytragoon-Lewin, N.1    Chen, F.2    Castro, J.3
  • 242
    • 79551689151 scopus 로고    scopus 로고
    • Frequent hypermethylation of DAPK, RARbeta, MGMT, RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa
    • Paluszczak J, Misiak P, Wierzbicka M, Wozniak A, Baer-Dubowska W. Frequent hypermethylation of DAPK, RARbeta, MGMT, RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa. Oral Oncol 2011;47:104-7.
    • (2011) Oral Oncol , vol.47 , pp. 104-107
    • Paluszczak, J.1    Misiak, P.2    Wierzbicka, M.3    Wozniak, A.4    Baer-Dubowska, W.5
  • 243
    • 79952817426 scopus 로고    scopus 로고
    • Hypermethylated DAPK in serum DNA of women with uterine leiomyoma is a biomarker not restricted to cancer
    • Hafner N, Diebolder H, Jansen L, Hoppe I, Durst M, Runnebaum IB. Hypermethylated DAPK in serum DNA of women with uterine leiomyoma is a biomarker not restricted to cancer. Gynecol Oncol 2011;121:224-9.
    • (2011) Gynecol Oncol , vol.121 , pp. 224-229
    • Hafner, N.1    Diebolder, H.2    Jansen, L.3    Hoppe, I.4    Durst, M.5    Runnebaum, I.B.6
  • 244
    • 79952376686 scopus 로고    scopus 로고
    • Hypermethylation of multiple tumor-related genes associated with DMNT3b up-regulation served as a biomarker for early diagnosis of esophageal squamous cell carcinoma
    • Li B, Wang B, Niu LJ, Jiang L, Qiu CC. Hypermethylation of multiple tumor-related genes associated with DMNT3b up-regulation served as a biomarker for early diagnosis of esophageal squamous cell carcinoma. Epigenetics 2011;6:307-16.
    • (2011) Epigenetics , vol.6 , pp. 307-316
    • Li, B.1    Wang, B.2    Niu, L.J.3    Jiang, L.4    Qiu, C.C.5
  • 245
    • 79955482440 scopus 로고    scopus 로고
    • Hypermethylation of tumor-related genes in tunisian patients with gastric carcinoma: Clinical and biological significance
    • Ben Ayed-Guerfali D, Benhaj K, Khabir A et al. Hypermethylation of tumor-related genes in tunisian patients with gastric carcinoma: Clinical and biological significance. J Surg Oncol 2011;103:687-94.
    • (2011) J Surg Oncol , vol.103 , pp. 687-694
    • Ben Ayed-Guerfali, D.1    Benhaj, K.2    Khabir, A.3
  • 246
    • 78651350836 scopus 로고    scopus 로고
    • Methylation of BNIP3 and DAPK indicates lower response to chemotherapy and poor prognosis in gastric cancer
    • Sugita H, Iida S, Inokuchi M et al. Methylation of BNIP3 and DAPK indicates lower response to chemotherapy and poor prognosis in gastric cancer. Oncol Rep 2011; 25:513-18.
    • (2011) Oncol Rep , vol.25 , pp. 513-518
    • Sugita, H.1    Iida, S.2    Inokuchi, M.3
  • 247
    • 79951850937 scopus 로고    scopus 로고
    • Methylation of multiple genes as a candidate biomarker in non-small cell lung cancer
    • Zhang Y, Wang R, Song H et al. Methylation of multiple genes as a candidate biomarker in non-small cell lung cancer. Cancer Lett 2011;303:21-8.
    • (2011) Cancer Lett , vol.303 , pp. 21-28
    • Zhang, Y.1    Wang, R.2    Song, H.3
  • 248
    • 78650504704 scopus 로고    scopus 로고
    • Promoter methylation of p16, Runx3, DAPK and CHFR genes is frequent in gastric carcinoma
    • Hu SL, Kong XY, Cheng ZD et al. Promoter methylation of p16, Runx3, DAPK and CHFR genes is frequent in gastric carcinoma. Tumori 2010;96:726-33.
    • (2010) Tumori , vol.96 , pp. 726-733
    • Hu, S.L.1    Kong, X.Y.2    Cheng, Z.D.3
  • 249
    • 77949463477 scopus 로고    scopus 로고
    • Quantitative methylation profiling in tumor and matched morphologically normal tissues from breast cancer patients
    • Van der Auwera I, Bovie C, Svensson C et al. Quantitative methylation profiling in tumor and matched morphologically normal tissues from breast cancer patients. BMC Cancer 2010;10:97-104.
    • (2010) BMC Cancer , vol.10 , pp. 97-104
    • Van der Auwera, I.1    Bovie, C.2    Svensson, C.3
  • 250
    • 79952398109 scopus 로고    scopus 로고
    • Relationship between promoter methylation of p16, DAPK and RAR beta genes and the clinical data of non-small cell lung cancer
    • Zhang C, Jin Y, Xu H et al. Relationship between promoter methylation of p16, DAPK and RAR beta genes and the clinical data of non-small cell lung cancer. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2011;28:23-28.
    • (2011) Zhonghua Yi Xue Yi Chuan Xue Za Zhi , vol.28 , pp. 23-28
    • Zhang, C.1    Jin, Y.2    Xu, H.3
  • 251
    • 77951489418 scopus 로고    scopus 로고
    • Value of promoter methylation of RASSF1A, p16, and DAPK genes in induced sputum in diagnosing lung cancers
    • Peng Z, Shan C, Wang H. Value of promoter methylation of RASSF1A, p16, and DAPK genes in induced sputum in diagnosing lung cancers. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010;35:247-53.
    • (2010) Zhong Nan Da Xue Xue Bao Yi Xue Ban , vol.35 , pp. 247-253
    • Peng, Z.1    Shan, C.2    Wang, H.3
  • 252
    • 84863362463 scopus 로고    scopus 로고
    • Aberrant promoter methylation of p16 in colorectal adenocarcinoma in North Indian patients
    • Malhotra P, Kochhar R, Vaiphei K, Wig JD, Mahmood S. Aberrant promoter methylation of p16 in colorectal adenocarcinoma in North Indian patients. World J Gastrointest Oncol 2010;2:295-303.
    • (2010) World J Gastrointest Oncol , vol.2 , pp. 295-303
    • Malhotra, P.1    Kochhar, R.2    Vaiphei, K.3    Wig, J.D.4    Mahmood, S.5
  • 253
    • 79951727256 scopus 로고    scopus 로고
    • Alterations in the tumor suppressor gene p16 (INK4A) are associated with aggressive behavior of penile carcinomas
    • Poetsch M, Hemmerich M, Kakies C et al. Alterations in the tumor suppressor gene p16 (INK4A) are associated with aggressive behavior of penile carcinomas. Virchows Arch 2011;458:221-29.
    • (2011) Virchows Arch , vol.458 , pp. 221-229
    • Poetsch, M.1    Hemmerich, M.2    Kakies, C.3
  • 254
    • 79957626217 scopus 로고    scopus 로고
    • Hypermethylation of E-cadherin, p16, p14, and RASSF1A genes in pathologically normal urothelium predict bladder recurrence of bladder cancer after transurethral resection
    • in press
    • Lin HH, Ke HL, Wu WJ, Lee YH, Chang LL. Hypermethylation of E-cadherin, p16, p14, and RASSF1A genes in pathologically normal urothelium predict bladder recurrence of bladder cancer after transurethral resection. Urol Oncol 2010; in press.
    • (2010) Urol Oncol
    • Lin, H.H.1    Ke, H.L.2    Wu, W.J.3    Lee, Y.H.4    Chang, L.L.5
  • 255
    • 78650703071 scopus 로고    scopus 로고
    • The influence of anthracosis and p16 ink4a gene aberrant methylation on small-sized pulmonary adenocarcinoma
    • Wang D, Wang J, Li Y, He Z, Zhang Y. The influence of anthracosis and p16 ink4a gene aberrant methylation on small-sized pulmonary adenocarcinoma. Exp Mol Pathol 2011;90:131-36.
    • (2011) Exp Mol Pathol , vol.90 , pp. 131-136
    • Wang, D.1    Wang, J.2    Li, Y.3    He, Z.4    Zhang, Y.5
  • 256
    • 79952362495 scopus 로고    scopus 로고
    • Quantitative evaluation of p16(INK4a) promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma
    • Zainuddin N, Kanduri M, Berglund M et al. Quantitative evaluation of p16(INK4a) promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma. Leuk Res 2011;35:438-43.
    • (2011) Leuk Res , vol.35 , pp. 438-443
    • Zainuddin, N.1    Kanduri, M.2    Berglund, M.3
  • 257
    • 77957376763 scopus 로고    scopus 로고
    • RE: P16 INK41 promoter hypermethylation is associated with invasiveness prognosis of oral squamous cell carcinoma in an age dependent manner. Su et al
    • Shaw R, Risk JM, Liloglou T. RE: P16 INK41 promoter hypermethylation is associated with invasiveness and prognosis of oral squamous cell carcinoma in an age dependent manner. Su et al. Oral Oncol 2010;46:734-39.
    • (2010) Oral Oncol , vol.46 , pp. 734-739
    • Shaw, R.1    Risk, J.M.2    Liloglou, T.3
  • 258
    • 79951868916 scopus 로고    scopus 로고
    • Integrated genetic and epigenetic analysis of bladder cancer reveals an additive diagnostic value of FGFR3 mutations and hypermethylation events
    • Serizawa RR, Ralfkiaer U, Steven K et al. Integrated genetic and epigenetic analysis of bladder cancer reveals an additive diagnostic value of FGFR3 mutations and hypermethylation events. Int J Cancer 2011;129:78-87.
    • (2011) Int J Cancer , vol.129 , pp. 78-87
    • Serizawa, R.R.1    Ralfkiaer, U.2    Steven, K.3
  • 259
    • 77950536708 scopus 로고    scopus 로고
    • Identification of 5 novel genes methylated in breast and other epithelial cancers
    • Hill VK, Hesson LB, Dansranjavin T et al. Identification of 5 novel genes methylated in breast and other epithelial cancers. Mol Cancer 2010;9:51-63.
    • (2010) Mol Cancer , vol.9 , pp. 51-63
    • Hill, V.K.1    Hesson, L.B.2    Dansranjavin, T.3
  • 260
    • 42549113460 scopus 로고    scopus 로고
    • Frequent hypermethylation of DBC1 in malignant lymphoproliferative neoplasms
    • Gronbaek K, Ralfkiaer U, Dahl C et al. Frequent hypermethylation of DBC1 in malignant lymphoproliferative neoplasms. Mod Pathol 2008;21:632-38.
    • (2008) Mod Pathol , vol.21 , pp. 632-638
    • Gronbaek, K.1    Ralfkiaer, U.2    Dahl, C.3
  • 261
    • 77952009891 scopus 로고    scopus 로고
    • Correlation of telomere length shortening with promoter methylation profile of p16/Rb and p53/p21 pathways in breast cancer
    • Radpour R, Barekati Z, Haghighi MM et al. Correlation of telomere length shortening with promoter methylation profile of p16/Rb and p53/p21 pathways in breast cancer. Mod Pathol 2010;23:763-72.
    • (2010) Mod Pathol , vol.23 , pp. 763-772
    • Radpour, R.1    Barekati, Z.2    Haghighi, M.M.3
  • 262
    • 13144298525 scopus 로고    scopus 로고
    • Functional promoter upstream p53 regulatory sequence of IGFBP3 that is silenced by tumor specific methylation
    • Hanafusa T, Shinji T, Shiraha H et al. Functional promoter upstream p53 regulatory sequence of IGFBP3 that is silenced by tumor specific methylation. BMC Cancer 2005;5:9-19.
    • (2005) BMC Cancer , vol.5 , pp. 9-19
    • Hanafusa, T.1    Shinji, T.2    Shiraha, H.3
  • 263
    • 78650553499 scopus 로고    scopus 로고
    • S-adenosylmethionine inhibits the growth of cancer cells by reversing the hypomethylation status of c-myc and H-ras in human gastric cancer and colon cancer
    • Luo J, Li YN, Wang F, Zhang WM, Geng X. S-adenosylmethionine inhibits the growth of cancer cells by reversing the hypomethylation status of c-myc and H-ras in human gastric cancer and colon cancer. Int J Biol Sci 2010;6:784-95.
    • (2010) Int J Biol Sci , vol.6 , pp. 784-795
    • Luo, J.1    Li, Y.N.2    Wang, F.3    Zhang, W.M.4    Geng, X.5
  • 264
    • 0029965028 scopus 로고    scopus 로고
    • Studies on the hypomethylation of c-myc, c-Ha-ras oncogenes and histopathological changes in human gastric carcinoma
    • Fang JY, Zhu SS, Xiao SD et al. Studies on the hypomethylation of c-myc, c-Ha-ras oncogenes and histopathological changes in human gastric carcinoma. J Gastroenterol Hepatol 1996;11:1079-82.
    • (1996) J Gastroenterol Hepatol , vol.11 , pp. 1079-1082
    • Fang, J.Y.1    Zhu, S.S.2    Xiao, S.D.3
  • 265
    • 0032735501 scopus 로고    scopus 로고
    • Hypomethylation of CpG sites and c-myc gene overexpression in hepatocellular carcinomas, but not hyperplastic nodules, induced by a choline-deficient L-amino acid-defined diet in rats
    • Tsujiuchi T, Tsutsumi M, Sasaki Y, Takahama M, Konishi Y. Hypomethylation of CpG sites and c-myc gene overexpression in hepatocellular carcinomas, but not hyperplastic nodules, induced by a choline-deficient L-amino acid-defined diet in rats. Jpn J Cancer Res 1999; 90:909-13.
    • (1999) Jpn J Cancer Res , vol.90 , pp. 909-913
    • Tsujiuchi, T.1    Tsutsumi, M.2    Sasaki, Y.3    Takahama, M.4    Konishi, Y.5
  • 266
    • 0030795755 scopus 로고    scopus 로고
    • Correlation between hypomethylation of c-myc and c-N-ras oncogenes and pathological changes in human hepatocellular carcinoma
    • Shen L, Qui D, Fang J. Correlation between hypomethylation of c-myc and c-N-ras oncogenes and pathological changes in human hepatocellular carcinoma. Zhonghua Zhong Liu Za Zhi 1997;19:173-76.
    • (1997) Zhonghua Zhong Liu Za Zhi , vol.19 , pp. 173-176
    • Shen, L.1    Qui, D.2    Fang, J.3
  • 267
    • 0024329935 scopus 로고
    • Differential hypomethylation of the c-myc protooncogene in bladder cancers at different stages and grades
    • Del Senno L, Maestri I, Piva R et al. Differential hypomethylation of the c-myc protooncogene in bladder cancers at different stages and grades. J Urol 1989;142: 146-49.
    • (1989) J Urol , vol.142 , pp. 146-149
    • Del Senno, L.1    Maestri, I.2    Piva, R.3
  • 268
    • 67649858977 scopus 로고    scopus 로고
    • Methylation analysis of BRCA1, RASSF1, GSTP1 and EPHB2 promoters in prostate biopsies according to different degrees of malignancy
    • Rabiau N, Thiam MO, Satih S et al. Methylation analysis of BRCA1, RASSF1, GSTP1 and EPHB2 promoters in prostate biopsies according to different degrees of malignancy. In Vivo 2009;23:387-91.
    • (2009) In Vivo , vol.23 , pp. 387-391
    • Rabiau, N.1    Thiam, M.O.2    Satih, S.3
  • 269
    • 77449124527 scopus 로고    scopus 로고
    • PTEN, RASSF1 and DAPK site-specific hypermethylation and outcome in surgically treated stage I and II nonsmall cell lung cancer patients
    • Buckingham L, Penfield Faber L, Kim A et al. PTEN, RASSF1 and DAPK site-specific hypermethylation and outcome in surgically treated stage I and II nonsmall cell lung cancer patients. Int J Cancer 2010;126:1630-39.
    • (2010) Int J Cancer , vol.126 , pp. 1630-1639
    • Buckingham, L.1    Penfield Faber, L.2    Kim, A.3
  • 270
    • 34247106791 scopus 로고    scopus 로고
    • Unventilated indoor coal-fired stoves in Guizhou province, China: cellular and genetic damage in villagers exposed to arsenic in food and air
    • Zhang A, Feng H, Yang G et al. Unventilated indoor coal-fired stoves in Guizhou province, China: cellular and genetic damage in villagers exposed to arsenic in food and air. Environ Health Perspect 2007;115:653-8.
    • (2007) Environ Health Perspect , vol.115 , pp. 653-658
    • Zhang, A.1    Feng, H.2    Yang, G.3
  • 271
    • 0035816153 scopus 로고    scopus 로고
    • Both hypomethylation and hypermethylation of DNA associated with arsenite exposure in cultures of human cells identified by methylationsensitive arbitrarily-primed PCR
    • Zhong CX, Mass MJ. Both hypomethylation and hypermethylation of DNA associated with arsenite exposure in cultures of human cells identified by methylationsensitive arbitrarily-primed PCR. Toxicol Lett 2001;122: 223-34.
    • (2001) Toxicol Lett , vol.122 , pp. 223-234
    • Zhong, C.X.1    Mass, M.J.2
  • 272
    • 48649093238 scopus 로고    scopus 로고
    • Decreased acetylation of histone H3 in renal cell carcinoma: a potential target of histone deacetylase inhibitors
    • Kanao K, Mikami S, Mizuno R, Shinojima T, Murai M, Oya M. Decreased acetylation of histone H3 in renal cell carcinoma: a potential target of histone deacetylase inhibitors. J Urol 2008;180:1131-36.
    • (2008) J Urol , vol.180 , pp. 1131-1136
    • Kanao, K.1    Mikami, S.2    Mizuno, R.3    Shinojima, T.4    Murai, M.5    Oya, M.6
  • 273
    • 70350616210 scopus 로고    scopus 로고
    • Acetylated H4K16 by MYST1 protects UROtsa cells from arsenic toxicity and is decreased following chronic arsenic exposure
    • Jo WJ, Ren XF, Chu FX et al. Acetylated H4K16 by MYST1 protects UROtsa cells from arsenic toxicity and is decreased following chronic arsenic exposure. Toxicol Appl Pharmacol 2009;241:294-302.
    • (2009) Toxicol Appl Pharmacol , vol.241 , pp. 294-302
    • Jo, W.J.1    Ren, X.F.2    Chu, F.X.3
  • 274
    • 77952983571 scopus 로고    scopus 로고
    • Progressive glomerulosclerosis in type 2 diabetes is associated with renal histone H3K9 and H3K23 acetylation, H3K4 dimethylation and phosphorylation at serine 10
    • Sayyed SG, Gaikwad AB, Lichtnekert J et al. Progressive glomerulosclerosis in type 2 diabetes is associated with renal histone H3K9 and H3K23 acetylation, H3K4 dimethylation and phosphorylation at serine 10. Nephrol Dial Transplant 2010;25:1811-17.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 1811-1817
    • Sayyed, S.G.1    Gaikwad, A.B.2    Lichtnekert, J.3
  • 275
    • 77749264372 scopus 로고    scopus 로고
    • Renal failure increases cardiac histone h3 acetylation, dimethylation, and phosphorylation and the induction of cardiomyopathy-related genes in type 2 diabetes
    • Gaikwad AB, Sayyed SG, Lichtnekert J, Tikoo K, Anders HJ. Renal failure increases cardiac histone h3 acetylation, dimethylation, and phosphorylation and the induction of cardiomyopathy-related genes in type 2 diabetes. Am J Pathol 2010;176:1079-83.
    • (2010) Am J Pathol , vol.176 , pp. 1079-1083
    • Gaikwad, A.B.1    Sayyed, S.G.2    Lichtnekert, J.3    Tikoo, K.4    Anders, H.J.5
  • 276
    • 32644479373 scopus 로고    scopus 로고
    • Immunohistochemical analysis of histone H3 acetylation and methylation - evidence for altered epigenetic signaling following traumatic brain injury in immature rats
    • Gao WM, Chadha MS, Kline AE et al. Immunohistochemical analysis of histone H3 acetylation and methylation - evidence for altered epigenetic signaling following traumatic brain injury in immature rats. Brain Res 2006;1070:31-4.
    • (2006) Brain Res , vol.1070 , pp. 31-34
    • Gao, W.M.1    Chadha, M.S.2    Kline, A.E.3
  • 277
    • 77957012141 scopus 로고    scopus 로고
    • Role of triptolide in cell proliferation, cell cycle arrest, apoptosis and histone methylation in multiple myeloma U266 cells
    • Zhao F, Chen Y, Zeng L et al. Role of triptolide in cell proliferation, cell cycle arrest, apoptosis and histone methylation in multiple myeloma U266 cells. Eur J Pharmacol 2010;646:1-11.
    • (2010) Eur J Pharmacol , vol.646 , pp. 1-11
    • Zhao, F.1    Chen, Y.2    Zeng, L.3
  • 278
    • 65649142216 scopus 로고    scopus 로고
    • Global Levels of Histone Modifications Predict Prognosis in Different Cancers
    • Seligson DB, Horvath S, McBrian MA et al. Global Levels of Histone Modifications Predict Prognosis in Different Cancers. Am J Pathol 2009;174:1619-28.
    • (2009) Am J Pathol , vol.174 , pp. 1619-1628
    • Seligson, D.B.1    Horvath, S.2    McBrian, M.A.3
  • 279
    • 70350665844 scopus 로고    scopus 로고
    • Epigenetics in metal carcinogenesis: Nickel, Arsenic, Chromium and Cadmium
    • Arita A, Costa M. Epigenetics in metal carcinogenesis: Nickel, Arsenic, Chromium and Cadmium. Metallomics 2009;1:222-28.
    • (2009) Metallomics , vol.1 , pp. 222-228
    • Arita, A.1    Costa, M.2
  • 280
    • 78049307486 scopus 로고    scopus 로고
    • H3K9 Histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM
    • Chen MW, Hua KT, Kao HJ et al. H3K9 Histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM. Cancer Res 2010;70:7830-40.
    • (2010) Cancer Res , vol.70 , pp. 7830-7840
    • Chen, M.W.1    Hua, K.T.2    Kao, H.J.3
  • 281
    • 77953301461 scopus 로고    scopus 로고
    • H3K27 trimethylation is an early epigenetic event of p16(INK4a) silencing for regaining tumorigenesis in fusion reprogrammed hepatoma cells
    • Yao JY, Zhang L, Zhang X et al. H3K27 trimethylation is an early epigenetic event of p16(INK4a) silencing for regaining tumorigenesis in fusion reprogrammed hepatoma cells. J Biol Chem 2010;285:18828-37.
    • (2010) J Biol Chem , vol.285 , pp. 18828-18837
    • Yao, J.Y.1    Zhang, L.2    Zhang, X.3
  • 282
    • 77951045228 scopus 로고    scopus 로고
    • Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML
    • Paul TA, Bies J, Small D, Wolff L. Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML. Blood 2010;115:3098-108.
    • (2010) Blood , vol.115 , pp. 3098-3108
    • Paul, T.A.1    Bies, J.2    Small, D.3    Wolff, L.4
  • 283
    • 44949093617 scopus 로고    scopus 로고
    • A rapid flow cytometry test based on histone H2AX phosphorylation for the sensitive and specific diagnosis of ataxia telangiectasia
    • Porcedda P, Turinetto V, Brusco A et al. A rapid flow cytometry test based on histone H2AX phosphorylation for the sensitive and specific diagnosis of ataxia telangiectasia. Cytometry A 2008;73:508-16.
    • (2008) Cytometry A , vol.73 , pp. 508-516
    • Porcedda, P.1    Turinetto, V.2    Brusco, A.3
  • 284
    • 69849115076 scopus 로고    scopus 로고
    • Disruption of histone modification and CARM1 recruitment by arsenic represses transcription at glucocorticoid receptor-regulated promoters
    • Barr FD, Krohmer LJ, Hamilton JW, Sheldon LA. Disruption of histone modification and CARM1 recruitment by arsenic represses transcription at glucocorticoid receptor-regulated promoters. PLoS One 2009;4:e6766.
    • (2009) PLoS One , vol.4
    • Barr, F.D.1    Krohmer, L.J.2    Hamilton, J.W.3    Sheldon, L.A.4
  • 285
    • 70149103990 scopus 로고    scopus 로고
    • Global histone H4 acetylation and HDAC2 expression in colon adenoma and carcinoma
    • Ashktorab H, Belgrave K, Hosseinkhah F et al. Global histone H4 acetylation and HDAC2 expression in colon adenoma and carcinoma. Digestive Dis Sci 2009;54: 2109-17.
    • (2009) Digestive Dis Sci , vol.54 , pp. 2109-2117
    • Ashktorab, H.1    Belgrave, K.2    Hosseinkhah, F.3
  • 286
    • 29144440077 scopus 로고    scopus 로고
    • MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation
    • Felli N, Fontana L, Pelosi E et al. MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc Natl Acad Sci USA 2005;102:18081-86.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18081-18086
    • Felli, N.1    Fontana, L.2    Pelosi, E.3
  • 287
    • 34547791273 scopus 로고    scopus 로고
    • Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation
    • le Sage C, Nagel R, Egan DA et al. Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J 2007;26: 3699-708.
    • (2007) EMBO J , vol.26 , pp. 3699-3708
    • le Sage, C.1    Nagel, R.2    Egan, D.A.3
  • 288
    • 70949104622 scopus 로고    scopus 로고
    • miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation
    • Garofalo M, Di Leva G, Romano G et al. miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation. Cancer Cell 2009;16:498-509.
    • (2009) Cancer Cell , vol.16 , pp. 498-509
    • Garofalo, M.1    Di Leva, G.2    Romano, G.3
  • 289
    • 84863340270 scopus 로고    scopus 로고
    • MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia
    • Mi SL, Lu J, Sun M et al. MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia. Blood 2007;110:75a.
    • (2007) Blood , vol.110
    • Mi, S.L.1    Lu, J.2    Sun, M.3
  • 290
    • 58849155669 scopus 로고    scopus 로고
    • Transcriptional repression of microRNA genes by PML-RARA increases expression of key cancer proteins in acute promyelocytic leukemia
    • Saumet A, Vetter G, Bouttier M et al. Transcriptional repression of microRNA genes by PML-RARA increases expression of key cancer proteins in acute promyelocytic leukemia. Blood 2009;113:412-21.
    • (2009) Blood , vol.113 , pp. 412-421
    • Saumet, A.1    Vetter, G.2    Bouttier, M.3
  • 291
    • 44049108170 scopus 로고    scopus 로고
    • Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression
    • Hebert SS, Horre K, Nicolai L et al. Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc Natl Acad Sci USA 2008;105:6415-20.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 6415-6420
    • Hebert, S.S.1    Horre, K.2    Nicolai, L.3
  • 292
    • 43549098845 scopus 로고    scopus 로고
    • Oncogenic role of miR-17-92 cluster in anaplastic thyroid cancer cells
    • Takakura S, Mitsutake N, Nakashima M et al. Oncogenic role of miR-17-92 cluster in anaplastic thyroid cancer cells. Cancer Sci 2008;99:1147-54.
    • (2008) Cancer Sci , vol.99 , pp. 1147-1154
    • Takakura, S.1    Mitsutake, N.2    Nakashima, M.3
  • 293
    • 4143142117 scopus 로고    scopus 로고
    • MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
    • Calin GA, Liu CG, Sevignani C et al. MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci USA 2004;101:11755-60.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11755-11760
    • Calin, G.A.1    Liu, C.G.2    Sevignani, C.3
  • 294
    • 70450260597 scopus 로고    scopus 로고
    • Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer
    • Arndt GM, Dossey L, Cullen LM et al. Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer. BMC Cancer 2009;9:374-90.
    • (2009) BMC Cancer , vol.9 , pp. 374-390
    • Arndt, G.M.1    Dossey, L.2    Cullen, L.M.3
  • 295
    • 33747628074 scopus 로고    scopus 로고
    • Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues
    • Bandres E, Cubedo E, Agirre X et al. Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol Cancer 2006;5:29-38.
    • (2006) Mol Cancer , vol.5 , pp. 29-38
    • Bandres, E.1    Cubedo, E.2    Agirre, X.3
  • 296
    • 77950824571 scopus 로고    scopus 로고
    • Identification and functional characterization of microRNAs involved in the malignant progression of astrocytic gliomas
    • Malzkorn B, Wolter M, Grzendowski M, Stuhler K, Reifenberger G. Identification and functional characterization of microRNAs involved in the malignant progression of astrocytic gliomas. Brain Pathol 2010;20:539-50.
    • (2010) Brain Pathol , vol.20 , pp. 539-550
    • Malzkorn, B.1    Wolter, M.2    Grzendowski, M.3    Stuhler, K.4    Reifenberger, G.5
  • 297
    • 33846941188 scopus 로고    scopus 로고
    • High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma
    • Hebert C, Norris K, Scheper MA, Nikitakis N, Sauk JJ. High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma. Mol Cancer 2007;6: 5-15.
    • (2007) Mol Cancer , vol.6 , pp. 5-15
    • Hebert, C.1    Norris, K.2    Scheper, M.A.3    Nikitakis, N.4    Sauk, J.J.5
  • 298
    • 40949087185 scopus 로고    scopus 로고
    • Identification of metastasis-related microRNAs in hepatocellular carcinoma
    • Budhu A, Jia HL, Forgues M et al. Identification of metastasis-related microRNAs in hepatocellular carcinoma. Hepatology 2008;47:897-907.
    • (2008) Hepatology , vol.47 , pp. 897-907
    • Budhu, A.1    Jia, H.L.2    Forgues, M.3
  • 299
    • 51349165812 scopus 로고    scopus 로고
    • Elevated expression of the miR-17-92 polycistron and miR-21 in hepadnavirus-associated hepatocellular carcinoma contributes to the malignant phenotype
    • Connolly E, Melegari M, Landgraf P et al. Elevated expression of the miR-17-92 polycistron and miR-21 in hepadnavirus-associated hepatocellular carcinoma contributes to the malignant phenotype. Am J Pathol 2008; 173:856-64.
    • (2008) Am J Pathol , vol.173 , pp. 856-864
    • Connolly, E.1    Melegari, M.2    Landgraf, P.3
  • 300
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
    • Hayashita Y, Osada H, Tatematsu Y et al. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 2005;65:9628-32.
    • (2005) Cancer Res , vol.65 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3
  • 301
    • 0346025548 scopus 로고    scopus 로고
    • Disruption of INK4/CDK/Rb cell cycle pathway by gene hypermethylation in multiple myeloma and MGUS
    • Chim CS, Fung TK, Liang R. Disruption of INK4/CDK/Rb cell cycle pathway by gene hypermethylation in multiple myeloma and MGUS. Leukemia 2003;17: 2533-35.
    • (2003) Leukemia , vol.17 , pp. 2533-2535
    • Chim, C.S.1    Fung, T.K.2    Liang, R.3
  • 302
    • 0030925099 scopus 로고    scopus 로고
    • Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors
    • Stirzaker C, Millar DS, Paul CL et al. Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors. Cancer Res 1997;57:2229-37.
    • (1997) Cancer Res , vol.57 , pp. 2229-2237
    • Stirzaker, C.1    Millar, D.S.2    Paul, C.L.3
  • 303
    • 2942754255 scopus 로고    scopus 로고
    • Methylation and expression analysis of p16(INK4a) and RB genes in meningiomas
    • Chen MN, Mao Q, Liu YH, Mao BY. Methylation and expression analysis of p16(INK4a) and RB genes in meningiomas. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2004;21:277-79.
    • (2004) Zhonghua Yi Xue Yi Chuan Xue Za Zhi , vol.21 , pp. 277-279
    • Chen, M.N.1    Mao, Q.2    Liu, Y.H.3    Mao, B.Y.4
  • 305
    • 79953733368 scopus 로고    scopus 로고
    • Methylation and expression of gene p16INK4a and RB in gastric carcinomas
    • Zhao Y, Tian X, Du J et al. Methylation and expression of gene p16INK4a and RB in gastric carcinomas. Beijing Da Xue Xue Bao 2003;35:382-85.
    • (2003) Beijing Da Xue Xue Bao , vol.35 , pp. 382-385
    • Zhao, Y.1    Tian, X.2    Du, J.3
  • 306
    • 0032449673 scopus 로고    scopus 로고
    • Study on the status of methylation of Rb gene promoter in human esophageal cancer and effect of NMBzA on Rb gene promoter in monkey esophageal epithelium
    • Li H, Lu S, Fong L. Study on the status of methylation of Rb gene promoter in human esophageal cancer and effect of NMBzA on Rb gene promoter in monkey esophageal epithelium. Zhonghua Zhong Liu Za Zhi 1998;20:412-14.
    • (1998) Zhonghua Zhong Liu Za Zhi , vol.20 , pp. 412-414
    • Li, H.1    Lu, S.2    Fong, L.3
  • 307
    • 33745603983 scopus 로고    scopus 로고
    • Alterations of histone modifications and transgene silencing by nickel chloride
    • Ke Q, Davidson T, Chen H, Kluz T, Costa M. Alterations of histone modifications and transgene silencing by nickel chloride. Carcinogenesis 2006;27:1481-88.
    • (2006) Carcinogenesis , vol.27 , pp. 1481-1488
    • Ke, Q.1    Davidson, T.2    Chen, H.3    Kluz, T.4    Costa, M.5
  • 308
    • 78049307486 scopus 로고    scopus 로고
    • H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM
    • Chen MW, Hua KT, Kao HJ et al. H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM. Cancer Res 2010;70:7830-40.
    • (2010) Cancer Res , vol.70 , pp. 7830-7840
    • Chen, M.W.1    Hua, K.T.2    Kao, H.J.3
  • 309
    • 78449235454 scopus 로고    scopus 로고
    • Altering a histone H3K4 methylation pathway in glomerular podocytes promotes a chronic disease phenotype
    • Lefevre GM, Patel SR, Kim D, Tessarollo L, Dressler GR. Altering a histone H3K4 methylation pathway in glomerular podocytes promotes a chronic disease phenotype. PLoS Genet 2010;6:e1001142.
    • (2010) PLoS Genet , vol.6
    • Lefevre, G.M.1    Patel, S.R.2    Kim, D.3    Tessarollo, L.4    Dressler, G.R.5
  • 310
    • 79952743720 scopus 로고    scopus 로고
    • Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice
    • Kumar R, Hunt CR, Gupta A et al. Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice. Proc Natl Acad Sci USA 2011;108:3636-41.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 3636-3641
    • Kumar, R.1    Hunt, C.R.2    Gupta, A.3
  • 311
    • 34447117003 scopus 로고    scopus 로고
    • Cyclin g1 is a target of miR-122a, a MicroRNA frequently down-regulated in human hepatocellular carcinoma
    • Gramantieri L, Ferracin M, Fornari F et al. Cyclin g1 is a target of miR-122a, a MicroRNA frequently down-regulated in human hepatocellular carcinoma. Cancer Res 2007;67:6092-99.
    • (2007) Cancer Res , vol.67 , pp. 6092-6099
    • Gramantieri, L.1    Ferracin, M.2    Fornari, F.3
  • 315
    • 78149258075 scopus 로고    scopus 로고
    • Microsatellite instability analysis and its correlation with hMLH1 repair gene hypermethylation status in esophageal pathologies including cancers
    • Vasavi M, Kiran V, Ravishankar B, Prabhakar B, Ahuja YR, Hasan Q. Microsatellite instability analysis and its correlation with hMLH1 repair gene hypermethylation status in esophageal pathologies including cancers. Cancer Biomark 2010;7:1-10.
    • (2010) Cancer Biomark , vol.7 , pp. 1-10
    • Vasavi, M.1    Kiran, V.2    Ravishankar, B.3    Prabhakar, B.4    Ahuja, Y.R.5    Hasan, Q.6
  • 316
    • 77956398232 scopus 로고    scopus 로고
    • Microsatellite instability with promoter methylation and silencing of hMLH1 can regionally occur during progression of gastric carcinoma
    • Ling ZQ, Tanaka A, Li P et al. Microsatellite instability with promoter methylation and silencing of hMLH1 can regionally occur during progression of gastric carcinoma. Cancer Lett 2010;297:244-51.
    • (2010) Cancer Lett , vol.297 , pp. 244-251
    • Ling, Z.Q.1    Tanaka, A.2    Li, P.3
  • 318
    • 57649119790 scopus 로고    scopus 로고
    • An NF-kappa B-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells
    • Lukiw WJ, Zhao YH, Cui JG. An NF-kappa B-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells. J Biol Chem 2008;283:31315-22.
    • (2008) J Biol Chem , vol.283 , pp. 31315-31322
    • Lukiw, W.J.1    Zhao, Y.H.2    Cui, J.G.3
  • 319
    • 70350035701 scopus 로고    scopus 로고
    • Characterization of an NF-kappa B-regulated, miRNA-146a-mediated downregulation of complement factor H (CFH) in metalsulfate-stressed human brain cells
    • Pogue AI, Li YY, Cui JG et al. Characterization of an NF-kappa B-regulated, miRNA-146a-mediated downregulation of complement factor H (CFH) in metalsulfate-stressed human brain cells. J Inorg Biochem 2009;103:1591-95.
    • (2009) J Inorg Biochem , vol.103 , pp. 1591-1595
    • Pogue, A.I.1    Li, Y.Y.2    Cui, J.G.3
  • 320
    • 34447318648 scopus 로고    scopus 로고
    • MicroRNAs are aberrantly expressed in hypertrophic heart - Do they play a role in cardiac hypertrophy?
    • Cheng YH, Ji RR, Yue JM et al. MicroRNAs are aberrantly expressed in hypertrophic heart - Do they play a role in cardiac hypertrophy? Am J Pathol 2007;170: 1831-40.
    • (2007) Am J Pathol , vol.170 , pp. 1831-1840
    • Cheng, Y.H.1    Ji, R.R.2    Yue, J.M.3
  • 321
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene target
    • Volinia S, Calin GA, Liu CG et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006;103:2257-61.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3
  • 322
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappa B-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov KD, Boldin MP, Chang KJ, Baltimore D. NF-kappa B-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 2006; 103:12481-86.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 323
    • 52149102044 scopus 로고    scopus 로고
    • Expression of microRNA-146 suppresses NF-kappa B activity with reduction of metastatic potential in breast cancer cells
    • Bhaumik D, Scott GK, Schokrpur S, Patil CK, Campisi J, Benz CC. Expression of microRNA-146 suppresses NF-kappa B activity with reduction of metastatic potential in breast cancer cells. Oncogene 2008;27:5643-5647.
    • (2008) Oncogene , vol.27 , pp. 5643-5647
    • Bhaumik, D.1    Scott, G.K.2    Schokrpur, S.3    Patil, C.K.4    Campisi, J.5    Benz, C.C.6
  • 324
    • 53349120042 scopus 로고    scopus 로고
    • A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis
    • Shen J, Ambrosone CB, DiCioccio RA, Odunsi K, Lele SB, Zhao H. A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis. Carcinogenesis 2008;29:1963-66.
    • (2008) Carcinogenesis , vol.29 , pp. 1963-1966
    • Shen, J.1    Ambrosone, C.B.2    DiCioccio, R.A.3    Odunsi, K.4    Lele, S.B.5    Zhao, H.6
  • 325
    • 27244434788 scopus 로고    scopus 로고
    • A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
    • Calin GA, Ferracin M, Cimmino A et al. A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. New Engl J Med 2005;353: 1793-801.
    • (2005) New Engl J Med , vol.353 , pp. 1793-1801
    • Calin, G.A.1    Ferracin, M.2    Cimmino, A.3
  • 326
    • 56049092548 scopus 로고    scopus 로고
    • A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma
    • Xu T, Zhu Y, Wei QK et al. A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma. Carcinogenesis 2008;29:2126-31.
    • (2008) Carcinogenesis , vol.29 , pp. 2126-2131
    • Xu, T.1    Zhu, Y.2    Wei, Q.K.3
  • 327
    • 41149086943 scopus 로고    scopus 로고
    • Unique MicroRNA molecular profiles in lung cancer diagnosis and prognosis
    • Yanaihara N, Caplen N, Bowman E et al. Unique MicroRNA molecular profiles in lung cancer diagnosis and prognosis. Toxicol Pathol 2006;34:1017-18.
    • (2006) Toxicol Pathol , vol.34 , pp. 1017-1018
    • Yanaihara, N.1    Caplen, N.2    Bowman, E.3
  • 328
    • 42049104107 scopus 로고    scopus 로고
    • Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer
    • Kozaki KI, Imoto I, Mogi S, Omura K, Inazawa J. Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res 2008;68:2094-105.
    • (2008) Cancer Res , vol.68 , pp. 2094-2105
    • Kozaki, K.I.1    Imoto, I.2    Mogi, S.3    Omura, K.4    Inazawa, J.5
  • 329
    • 34548177451 scopus 로고    scopus 로고
    • Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells
    • Lukiw WJ, Pogue AI. Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells. J Inorg Biochem 2007;101: 1265-69.
    • (2007) J Inorg Biochem , vol.101 , pp. 1265-1269
    • Lukiw, W.J.1    Pogue, A.I.2
  • 330
    • 33847203593 scopus 로고    scopus 로고
    • Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus
    • Lukiw WJ. Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport 2007;18: 297-300.
    • (2007) Neuroreport , vol.18 , pp. 297-300
    • Lukiw, W.J.1
  • 332
    • 48749084382 scopus 로고    scopus 로고
    • MicroRNA signatures characterize diffuse large B-cell lymphomas and follicular lymphomas
    • Roehle A, Hoefig KP, Repsilber D et al. MicroRNA signatures characterize diffuse large B-cell lymphomas and follicular lymphomas. British J Haematol 2008;142: 732-44.
    • (2008) British J Haematol , vol.142 , pp. 732-744
    • Roehle, A.1    Hoefig, K.P.2    Repsilber, D.3
  • 333
    • 45149128115 scopus 로고    scopus 로고
    • Profiling MicroRNA expression in hepatocellular carcinoma reveals MicroRNA-224 up-regulation and apoptosis inhibitor-5 as a MicroRNA-224-specific target
    • Wang Y, Lee ATC, Ma JZI et al. Profiling MicroRNA expression in hepatocellular carcinoma reveals MicroRNA-224 up-regulation and apoptosis inhibitor-5 as a MicroRNA-224-specific target. J Biol Chem 2008; 283:13205-15.
    • (2008) J Biol Chem , vol.283 , pp. 13205-13215
    • Wang, Y.1    Lee, A.T.C.2    Ma, J.Z.I.3
  • 334
    • 77956941692 scopus 로고    scopus 로고
    • MicroRNA-9 reduces cell invasion and E-cadherin secretion in SK-Hep-1 cell
    • Tan HX, Wang QA, Chen LZ et al. MicroRNA-9 reduces cell invasion and E-cadherin secretion in SK-Hep-1 cell. Med Oncol 2010;27:654-60.
    • (2010) Med Oncol , vol.27 , pp. 654-660
    • Tan, H.X.1    Wang, Q.A.2    Chen, L.Z.3
  • 335
    • 63449123568 scopus 로고    scopus 로고
    • MiRNA expression in urothelial carcinomas: Important roles of miR-10a, miR-222, miR-125b, miR-7 and miR-452 for tumor stage and metastasis, and frequent homozygous losses of miR-31
    • Veerla S, Lindgren D, Kvist A et al. MiRNA expression in urothelial carcinomas: Important roles of miR-10a, miR-222, miR-125b, miR-7 and miR-452 for tumor stage and metastasis, and frequent homozygous losses of miR-31. Int J Cancer 2009;124:2236-42.
    • (2009) Int J Cancer , vol.124 , pp. 2236-2242
    • Veerla, S.1    Lindgren, D.2    Kvist, A.3
  • 336
    • 41149140859 scopus 로고    scopus 로고
    • Epigenomic profiling reveals DNA-methylation changes associated with major psychosis
    • Mill J, Tang T, Kaminsky Z et al. Epigenomic profiling reveals DNA-methylation changes associated with major psychosis. Am J Hum Genet 2008;82:696-711.
    • (2008) Am J Hum Genet , vol.82 , pp. 696-711
    • Mill, J.1    Tang, T.2    Kaminsky, Z.3
  • 337
    • 49949108971 scopus 로고    scopus 로고
    • Age-specific epigenetic drift in late-onset Alzheimer's disease
    • Wang SC, Oelze B, Schumacher A. Age-specific epigenetic drift in late-onset Alzheimer's disease. PLoS One 2008;3:e2698.
    • (2008) PLoS One , vol.3
    • Wang, S.C.1    Oelze, B.2    Schumacher, A.3
  • 338
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M. Epigenetics in cancer. N Engl J Med 2008;358: 1148-59.
    • (2008) N Engl J Med , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 339
    • 51349143015 scopus 로고    scopus 로고
    • Neurogenin 2 controls cortical neuron migration through regulation of Rnd2
    • Heng JI, Nguyen L, Castro DS et al. Neurogenin 2 controls cortical neuron migration through regulation of Rnd2. Nature 2008;455:114-18.
    • (2008) Nature , vol.455 , pp. 114-118
    • Heng, J.I.1    Nguyen, L.2    Castro, D.S.3
  • 340
    • 33846844870 scopus 로고    scopus 로고
    • Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors
    • Pereira MA, Tao L, Liu Y, Li L, Steele VE, Lubet RA. Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors. Int J Cancer 2007;120:1150-53.
    • (2007) Int J Cancer , vol.120 , pp. 1150-1153
    • Pereira, M.A.1    Tao, L.2    Liu, Y.3    Li, L.4    Steele, V.E.5    Lubet, R.A.6
  • 341
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 2005;65:6029-33.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 342
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio MV, Ferracin M, Liu CG et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005;65:7065-70.
    • (2005) Cancer Res , vol.65 , pp. 7065-7070
    • Iorio, M.V.1    Ferracin, M.2    Liu, C.G.3
  • 343
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    • Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A, Lund AH. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 2008;283: 1026-33.
    • (2008) J Biol Chem , vol.283 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 344
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • Zhu SM, Si ML, Wu HL, Mo YY. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem 2007;282:14328-36.
    • (2007) J Biol Chem , vol.282 , pp. 14328-14336
    • Zhu, S.M.1    Si, M.L.2    Wu, H.L.3    Mo, Y.Y.4
  • 345
    • 38749089854 scopus 로고    scopus 로고
    • MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
    • Schetter AJ, Leung SY, Sohn JJ et al. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 2008;299: 425-36.
    • (2008) JAMA , vol.299 , pp. 425-436
    • Schetter, A.J.1    Leung, S.Y.2    Sohn, J.J.3
  • 346
    • 34247862190 scopus 로고    scopus 로고
    • MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis
    • Bloomston M, Frankel WL, Petrocca F et al. MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA 2007;297:1901-08.
    • (2007) JAMA , vol.297 , pp. 1901-1908
    • Bloomston, M.1    Frankel, W.L.2    Petrocca, F.3
  • 347
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng FY, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 2007;133: 647-58.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.Y.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 348
    • 65449156487 scopus 로고    scopus 로고
    • Promoter methylation status of p15 and p21 genes in HPP-CFCs of bone marrow of patients with psoriasis
    • Zhang K, Zhang R, Li X, Yin G, Niu X. Promoter methylation status of p15 and p21 genes in HPP-CFCs of bone marrow of patients with psoriasis. Eur J Dermatol 2009; 19:141-46.
    • (2009) Eur J Dermatol , vol.19 , pp. 141-146
    • Zhang, K.1    Zhang, R.2    Li, X.3    Yin, G.4    Niu, X.5
  • 349
    • 4344672497 scopus 로고    scopus 로고
    • Aberrant methylation of p14(ARF), p15(INK4b) and p16(INK4a) genes and location of the primary site in pulmonary squamous cell carcinoma
    • Furonaka O, Takeshima Y, Awaya H, Ishida H, Kohno N, Inai K. Aberrant methylation of p14(ARF), p15(INK4b) and p16(INK4a) genes and location of the primary site in pulmonary squamous cell carcinoma. Pathol Int 2004; 54:549-55.
    • (2004) Pathol Int , vol.54 , pp. 549-555
    • Furonaka, O.1    Takeshima, Y.2    Awaya, H.3    Ishida, H.4    Kohno, N.5    Inai, K.6
  • 350
    • 38049153551 scopus 로고    scopus 로고
    • Evaluation of CDKN2C/p18, CDKN1B/p27 and CDKN2B/p15 mRNA expression, and CpG methylation status in sporadic and MEN1-associated pancreatic endocrine tumours
    • Lindberg D, Akerstrom G, Westin G. Evaluation of CDKN2C/p18, CDKN1B/p27 and CDKN2B/p15 mRNA expression, and CpG methylation status in sporadic and MEN1-associated pancreatic endocrine tumours. Clin Endocrinol 2008;68:271-77.
    • (2008) Clin Endocrinol , vol.68 , pp. 271-277
    • Lindberg, D.1    Akerstrom, G.2    Westin, G.3
  • 351
    • 70349876858 scopus 로고    scopus 로고
    • Homozygous deletion of CDKN2A (p16, p14) and CDKN2B (p15) genes is a poor prognostic factor in adult but not in childhood B-lineage acute lymphoblastic leukemia: a comparative deletion and hypermethylation study
    • Kim M, Yim SH, Cho NS et al. Homozygous deletion of CDKN2A (p16, p14) and CDKN2B (p15) genes is a poor prognostic factor in adult but not in childhood B-lineage acute lymphoblastic leukemia: a comparative deletion and hypermethylation study. Cancer Genet Cytogenet 2009;195:59-65.
    • (2009) Cancer Genet Cytogenet , vol.195 , pp. 59-65
    • Kim, M.1    Yim, S.H.2    Cho, N.S.3
  • 352
    • 18044374452 scopus 로고    scopus 로고
    • Methylation of p15(INK4b) and E-cadherin genes is independently correlated with poor prognosis in acute myeloid leukemia
    • Shimamoto T, Ohyashiki JH, Ohyashiki K. Methylation of p15(INK4b) and E-cadherin genes is independently correlated with poor prognosis in acute myeloid leukemia. Leuk Res 2005;29:653-59.
    • (2005) Leuk Res , vol.29 , pp. 653-659
    • Shimamoto, T.1    Ohyashiki, J.H.2    Ohyashiki, K.3
  • 353
    • 0347955433 scopus 로고    scopus 로고
    • Methylation of p16 and p15 genes in multiple myeloma
    • Chen W, Wu Y, Zhu J, Liu J, Tan S, Xia C. Methylation of p16 and p15 genes in multiple myeloma. Clin Med Sci J. 2002;17:101-05.
    • (2002) Clin Med Sci J , vol.17 , pp. 101-105
    • Chen, W.1    Wu, Y.2    Zhu, J.3    Liu, J.4    Tan, S.5    Xia, C.6
  • 354
    • 9144229469 scopus 로고    scopus 로고
    • Methylation status of the p15, p16 and MGMT promoter genes in primary cutaneous T-cell lymphomas
    • Gallardo F, Esteller M, Pujol RM, Costa C, Estrach T, Servitje O. Methylation status of the p15, p16 and MGMT promoter genes in primary cutaneous T-cell lymphomas. Haematologica 2004;89:1401-403.
    • (2004) Haematologica , vol.89 , pp. 1401-1403
    • Gallardo, F.1    Esteller, M.2    Pujol, R.M.3    Costa, C.4    Estrach, T.5    Servitje, O.6
  • 355
    • 34548855398 scopus 로고    scopus 로고
    • Mossallam GI. p15 (INK4B) and E-cadherin CpG island methylation is frequent in Egyptian acute myeloid leukemia
    • El-Shakankiry NH, Mossallam GI. p15 (INK4B) and E-cadherin CpG island methylation is frequent in Egyptian acute myeloid leukemia. J Egypt Natl Canc Inst 2006;18:227-32.
    • (2006) J Egypt Natl Canc Inst , vol.18 , pp. 227-232
    • El-Shakankiry, N.H.1
  • 356
    • 14744273622 scopus 로고    scopus 로고
    • p15 mRNA expression detected by real-time quantitative reverse transcriptase-polymerase chain reaction correlates with the methylation density of the gene in adult acute leukemia
    • Matsuno N, Hoshino K, Nanri T et al. p15 mRNA expression detected by real-time quantitative reverse transcriptase-polymerase chain reaction correlates with the methylation density of the gene in adult acute leukemia. Leuk Res 2005;29:557-64.
    • (2005) Leuk Res , vol.29 , pp. 557-564
    • Matsuno, N.1    Hoshino, K.2    Nanri, T.3
  • 357
    • 67649442519 scopus 로고    scopus 로고
    • p15 promoter methylation - a novel prognostic marker in glioblastoma patients
    • Wemmert S, Bettscheider M, Alt S et al. p15 promoter methylation - a novel prognostic marker in glioblastoma patients. Int J Oncol 2009;34:1743-48.
    • (2009) Int J Oncol , vol.34 , pp. 1743-1748
    • Wemmert, S.1    Bettscheider, M.2    Alt, S.3
  • 358
    • 67651108667 scopus 로고    scopus 로고
    • Promoter methylation of P15(INK4B) gene is possibly associated with parvovirus B19 infection in adult acute leukemias
    • Yalcin A, Serin MS, Emekdas G et al. Promoter methylation of P15(INK4B) gene is possibly associated with parvovirus B19 infection in adult acute leukemias. Int J Lab Hematol 2009;31:407-19.
    • (2009) Int J Lab Hematol , vol.31 , pp. 407-419
    • Yalcin, A.1    Serin, M.S.2    Emekdas, G.3
  • 359
    • 33846820578 scopus 로고    scopus 로고
    • Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines
    • Berg T, Guo Y, Abdelkarim M, Fliegauf M, Lubbert M. Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines. Leuk Res 2007;31:497-506.
    • (2007) Leuk Res , vol.31 , pp. 497-506
    • Berg, T.1    Guo, Y.2    Abdelkarim, M.3    Fliegauf, M.4    Lubbert, M.5
  • 360
    • 0142058246 scopus 로고    scopus 로고
    • The study of p16 and p15 gene methylation in head and neck squamous cell carcinoma and their quantitative evaluation in plasma by real-time PCR
    • Wong TS, Man MW, Lam AK, Wei WI, Kwong YL, Yuen AP. The study of p16 and p15 gene methylation in head and neck squamous cell carcinoma and their quantitative evaluation in plasma by real-time PCR. Eur J Cancer 2003;39:1881-87.
    • (2003) Eur J Cancer , vol.39 , pp. 1881-1887
    • Wong, T.S.1    Man, M.W.2    Lam, A.K.3    Wei, W.I.4    Kwong, Y.L.5    Yuen, A.P.6
  • 361
    • 77955854156 scopus 로고    scopus 로고
    • Differential effects of insulin on sympathetic nerve activity in agouti obese mice
    • Morgan DA, Rahmouni K. Differential effects of insulin on sympathetic nerve activity in agouti obese mice. J Hypertens 2010;28:1913-19.
    • (2010) J Hypertens , vol.28 , pp. 1913-1919
    • Morgan, D.A.1    Rahmouni, K.2
  • 362
    • 77953111939 scopus 로고    scopus 로고
    • Pharmacological characterization of 30 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists, synthetic agonists, and the endogenous agoutirelated protein antagonist
    • Xiang Z, Proneth B, Dirain ML, Litherland SA, Haskell-Luevano C. Pharmacological characterization of 30 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists, synthetic agonists, and the endogenous agoutirelated protein antagonist. Biochemistry 2010;49: 4583-600.
    • (2010) Biochemistry , vol.49 , pp. 4583-4600
    • Xiang, Z.1    Proneth, B.2    Dirain, M.L.3    Litherland, S.A.4    Haskell-Luevano, C.5
  • 363
    • 70350787154 scopus 로고    scopus 로고
    • A case of Silver-Russell syndrome (SRS): multiple pituitary hormone deficiency, lack of H19 hypomethylation and favourable growth hormone (GH) treatment response
    • Gucev ZS, Tasic V, Jancevska A, Kirovski I. A case of Silver-Russell syndrome (SRS): multiple pituitary hormone deficiency, lack of H19 hypomethylation and favourable growth hormone (GH) treatment response. J Genet 2009;88:239-43.
    • (2009) J Genet , vol.88 , pp. 239-243
    • Gucev, Z.S.1    Tasic, V.2    Jancevska, A.3    Kirovski, I.4
  • 364
    • 39749173843 scopus 로고    scopus 로고
    • IGF2/H19 hypomethylation in Silver-Russell syndrome and isolated hemihypoplasia
    • Zeschnigk M, Albrecht B, Buiting K et al. IGF2/H19 hypomethylation in Silver-Russell syndrome and isolated hemihypoplasia. Eur J Hum Genet 2008;16:328-34.
    • (2008) Eur J Hum Genet , vol.16 , pp. 328-334
    • Zeschnigk, M.1    Albrecht, B.2    Buiting, K.3
  • 365
    • 77957790511 scopus 로고    scopus 로고
    • Russell-Silver syndrome due to paternal H19/IGF2 hypomethylation in a patient conceived using intracytoplasmic sperm injection
    • Chopra M, Amor DJ, Sutton L, Algar E, Mowat D. Russell-Silver syndrome due to paternal H19/IGF2 hypomethylation in a patient conceived using intracytoplasmic sperm injection. Reprod Biomed Online 2010;20: 843-47.
    • (2010) Reprod Biomed Online , vol.20 , pp. 843-847
    • Chopra, M.1    Amor, D.J.2    Sutton, L.3    Algar, E.4    Mowat, D.5
  • 366
    • 74549162340 scopus 로고    scopus 로고
    • Frequent aberrant methylation of the imprinted IGF2/H19 locus and LINE1 hypomethylation in ovarian carcinoma
    • Dammann RH, Kirsch S, Schagdarsurengin U et al. Frequent aberrant methylation of the imprinted IGF2/H19 locus and LINE1 hypomethylation in ovarian carcinoma. Int J Oncol 2010;36:171-79.
    • (2010) Int J Oncol , vol.36 , pp. 171-179
    • Dammann, R.H.1    Kirsch, S.2    Schagdarsurengin, U.3
  • 367
    • 78649693873 scopus 로고    scopus 로고
    • Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis
    • Baba Y, Nosho K, Shima K et al. Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis. Gastroenterology 2010;139:1855-64.
    • (2010) Gastroenterology , vol.139 , pp. 1855-1864
    • Baba, Y.1    Nosho, K.2    Shima, K.3
  • 368
    • 69949174705 scopus 로고    scopus 로고
    • Hypomethylation of the P3 promoter is associated with up-regulation of IGF2 expression in human osteosarcoma
    • Li Y, Meng G, Huang L, Guo QN. Hypomethylation of the P3 promoter is associated with up-regulation of IGF2 expression in human osteosarcoma. Hum Pathol 2009;40: 1441-47.
    • (2009) Hum Pathol , vol.40 , pp. 1441-1447
    • Li, Y.1    Meng, G.2    Huang, L.3    Guo, Q.N.4
  • 369
    • 0037112364 scopus 로고    scopus 로고
    • Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2
    • Cui H, Onyango P, Brandenburg S, Wu Y, Hsieh CL, Feinberg AP. Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2. Cancer Res 2002;62:6442-46.
    • (2002) Cancer Res , vol.62 , pp. 6442-6446
    • Cui, H.1    Onyango, P.2    Brandenburg, S.3    Wu, Y.4    Hsieh, C.L.5    Feinberg, A.P.6
  • 370
    • 49649112211 scopus 로고    scopus 로고
    • Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer
    • Ito Y, Koessler T, Ibrahim AE et al. Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer. Hum Mol Genet 2008;17:2633-43.
    • (2008) Hum Mol Genet , vol.17 , pp. 2633-2643
    • Ito, Y.1    Koessler, T.2    Ibrahim, A.E.3
  • 371
    • 85128713958 scopus 로고    scopus 로고
    • Prognostic values of microRNAs in colorectal cancer
    • Xi Y, Formentini A, Chien M et al. Prognostic values of microRNAs in colorectal cancer. Biomark Insights 2006;2: 113-21.
    • (2006) Biomark Insights , vol.2 , pp. 113-121
    • Xi, Y.1    Formentini, A.2    Chien, M.3
  • 372
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • Volinia S, Calin GA, Liu CG et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006;103:2257-61.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3
  • 373
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, Dumitru CD, Shimizu M et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2002;99: 15524-29.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3
  • 374
    • 25444520537 scopus 로고    scopus 로고
    • miR-15 and miR-16 induce apoptosis by targeting BCL2
    • Cimmino A, Calin GA, Fabbri M et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 2005;102:13944-49.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13944-13949
    • Cimmino, A.1    Calin, G.A.2    Fabbri, M.3
  • 375
    • 51049123624 scopus 로고    scopus 로고
    • Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer
    • Ambs S, Prueitt RL, Yi M et al. Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer. Cancer Res 2008;68:6162-70.
    • (2008) Cancer Res , vol.68 , pp. 6162-6170
    • Ambs, S.1    Prueitt, R.L.2    Yi, M.3
  • 376
    • 69249225706 scopus 로고    scopus 로고
    • MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma
    • Roccaro AM, Sacco A, Thompson B et al. MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma. Blood 2009;113:6669-80.
    • (2009) Blood , vol.113 , pp. 6669-6680
    • Roccaro, A.M.1    Sacco, A.2    Thompson, B.3
  • 377
    • 20044395613 scopus 로고    scopus 로고
    • RAS is regulated by the let-7 MicroRNA family
    • Johnson SM, Grosshans H, Shingara J et al. RAS is regulated by the let-7 MicroRNA family. Cell 2005;120: 635-47.
    • (2005) Cell , vol.120 , pp. 635-647
    • Johnson, S.M.1    Grosshans, H.2    Shingara, J.3
  • 378
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee YS, Dutta A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev 2007;21: 1025-30.
    • (2007) Genes Dev , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 379
    • 33644819964 scopus 로고    scopus 로고
    • Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
    • Yanaihara N, Caplen N, Bowman E et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 2006;9:189-98.
    • (2006) Cancer Cell , vol.9 , pp. 189-198
    • Yanaihara, N.1    Caplen, N.2    Bowman, E.3
  • 380
    • 35449003175 scopus 로고    scopus 로고
    • MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
    • Sampson VB, Rong NH, Han J et al. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 2007;67: 9762-70.
    • (2007) Cancer Res , vol.67 , pp. 9762-9770
    • Sampson, V.B.1    Rong, N.H.2    Han, J.3
  • 381
    • 34250843675 scopus 로고    scopus 로고
    • The microribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ER alpha) and represses ER alpha messenger RNA and protein expression in breast cancer cell lines
    • Adams BD, Furneaux H, White BA. The microribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ER alpha) and represses ER alpha messenger RNA and protein expression in breast cancer cell lines. Mol Endocrinol 2007;21:1132-47.
    • (2007) Mol Endocrinol , vol.21 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.A.3
  • 382
    • 84863390611 scopus 로고    scopus 로고
    • MicroRNA expression in the biology, prognosis, and therapy of waldenstrom macroglobulinemia
    • Roccaro AM, Jia X, Ngo HT et al. MicroRNA expression in the biology, prognosis, and therapy of waldenstrom macroglobulinemia. Clin Lymphoma Myeloma 2009;9: S126.
    • (2009) Clin Lymphoma Myeloma , vol.9
    • Roccaro, A.M.1    Jia, X.2    Ngo, H.T.3
  • 383
    • 47749117212 scopus 로고    scopus 로고
    • Distinctive patterns of microrna expression associated with karyotype in acute myeloid leukaemia
    • Dixon-McIver A, East P, Mein CA et al. Distinctive patterns of microrna expression associated with karyotype in acute myeloid leukaemia. PLos One 2008;3:e2141.
    • (2008) PLos One , vol.3
    • Dixon-McIver, A.1    East, P.2    Mein, C.A.3
  • 384
    • 33845317603 scopus 로고    scopus 로고
    • A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure
    • van Rooij E, Sutherland LB, Liu N et al. A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci USA 2006;103:18255-60.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 18255-18260
    • van Rooij, E.1    Sutherland, L.B.2    Liu, N.3
  • 385
    • 33847038668 scopus 로고    scopus 로고
    • MicroRNAs play an essential role in the development of cardiac hypertrophy
    • Sayed D, Hong C, Chen IY, Lypowy J, Abdellatif M. MicroRNAs play an essential role in the development of cardiac hypertrophy. Circulation Res 2007;100:416-24.
    • (2007) Circulation Res , vol.100 , pp. 416-424
    • Sayed, D.1    Hong, C.2    Chen, I.Y.3    Lypowy, J.4    Abdellatif, M.5


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