Combined inhaled diesel exhaust particles and allergen exposure alter methylation of T helper genes and Ige production in vivo

Toxicological Sciences

Volumn 102, Issue 1, 2008, Pages 76-81

  Liu, Jinming ^a   Ballaney, Manisha ^a   Al Alem, Umaima ^a   Quan, Chunli ^b   Jin, Ximei ^b   Perera, Frederica ^c   Chen, Lung Chi ^b   Miller, Rachel I ^a  

^a Columbia University College of Physicians and Surgeons ^*  (United States)

^b NEW YORK UNIVERSITY   (United States)

^c Columbia University ^*  (United States)

Author keywords

Cytokines; Environmental exposure; Epigenetic modification; Inhalation toxicology; Respiratory sensitization

Indexed keywords

ALLERGEN; BISULFITE; CYTOKINE; DIESEL FUEL; DNA; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 4;

AIR POLLUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLUS FUMIGATUS; ASTHMA; BAGG ALBINO MOUSE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DNA PURIFICATION; ENVIRONMENTAL EXPOSURE; EXHAUST GAS; FEMALE; GENE AMPLIFICATION; HELPER CELL; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; IMMUNOREGULATION; IN VIVO STUDY; INHALATION; MOUSE; NONHUMAN; PATHOGENESIS; POLYMERASE CHAIN REACTION; PROMOTER REGION; SENSITIZATION; SPLEEN LYMPHOCYTE;

ALLERGENS; ANIMALS; ASPERGILLUS FUMIGATUS; ASTHMA; CPG ISLANDS; DISEASE MODELS, ANIMAL; DNA METHYLATION; FEMALE; IMMUNOGLOBULIN E; INHALATION EXPOSURE; INTERFERON TYPE II; INTERLEUKIN-4; MICE; MICE, INBRED BALB C; PROMOTER REGIONS (GENETICS); T-LYMPHOCYTES, HELPER-INDUCER; VEHICLE EMISSIONS;

ASPERGILLUS FUMIGATUS; FUNGI; MUS;

EID: 39449123898     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm290     Document Type: Article

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