메뉴 건너뛰기




Volumn 82, Issue 3, 2008, Pages 696-711

Epigenomic Profiling Reveals DNA-Methylation Changes Associated with Major Psychosis

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1;

EID: 41149140859     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajhg.2008.01.008     Document Type: Article
Times cited : (671)

References (63)
  • 1
    • 30344447674 scopus 로고    scopus 로고
    • Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology
    • Craddock N., O'Donovan M.C., and Owen M.J. Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophr. Bull. 32 (2006) 9-16
    • (2006) Schizophr. Bull. , vol.32 , pp. 9-16
    • Craddock, N.1    O'Donovan, M.C.2    Owen, M.J.3
  • 2
    • 15044363048 scopus 로고    scopus 로고
    • The genetics of schizophrenia and bipolar disorder: dissecting psychosis
    • Craddock N., O'Donovan M.C., and Owen M.J. The genetics of schizophrenia and bipolar disorder: dissecting psychosis. J. Med. Genet. 42 (2005) 193-204
    • (2005) J. Med. Genet. , vol.42 , pp. 193-204
    • Craddock, N.1    O'Donovan, M.C.2    Owen, M.J.3
  • 3
    • 2342509705 scopus 로고    scopus 로고
    • The origin of schizophrenia: genetic thesis, epigenetic antithesis, and resolving synthesis
    • Petronis A. The origin of schizophrenia: genetic thesis, epigenetic antithesis, and resolving synthesis. Biol Psychiatry 55 (2004) 965-970
    • (2004) Biol Psychiatry , vol.55 , pp. 965-970
    • Petronis, A.1
  • 4
    • 0032803524 scopus 로고    scopus 로고
    • Genetics of bipolar disorder
    • Craddock N., and Jones I. Genetics of bipolar disorder. J. Med. Genet. 36 (1999) 585-594
    • (1999) J. Med. Genet. , vol.36 , pp. 585-594
    • Craddock, N.1    Jones, I.2
  • 5
    • 0028275174 scopus 로고
    • The strength of the genetic effect. Is there room for an environmental influence in the aetiology of schizophrenia?
    • McGuffin P., Asherson P., Owen M., and Farmer A. The strength of the genetic effect. Is there room for an environmental influence in the aetiology of schizophrenia?. Br. J. Psychiatry 164 (1994) 593-599
    • (1994) Br. J. Psychiatry , vol.164 , pp. 593-599
    • McGuffin, P.1    Asherson, P.2    Owen, M.3    Farmer, A.4
  • 6
    • 0031201685 scopus 로고    scopus 로고
    • Exploring and explaining epigenetic effects
    • Henikoff S., and Matzke M.A. Exploring and explaining epigenetic effects. Trends Genet. 13 (1997) 293-295
    • (1997) Trends Genet. , vol.13 , pp. 293-295
    • Henikoff, S.1    Matzke, M.A.2
  • 7
    • 0031617319 scopus 로고    scopus 로고
    • Methylation dynamics, epigenetic fidelity and X chromosome structure
    • Riggs A.D., Xiong Z., Wang L., and LeBon J.M. Methylation dynamics, epigenetic fidelity and X chromosome structure. Novartis Found. Symp. 214 (1998) 214-225
    • (1998) Novartis Found. Symp. , vol.214 , pp. 214-225
    • Riggs, A.D.1    Xiong, Z.2    Wang, L.3    LeBon, J.M.4
  • 8
    • 33646193822 scopus 로고    scopus 로고
    • Inherited epigenetic variation-revisiting soft inheritance
    • Richards E.J. Inherited epigenetic variation-revisiting soft inheritance. Nat. Rev. Genet. 7 (2006) 395-401
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 395-401
    • Richards, E.J.1
  • 11
    • 38949150121 scopus 로고    scopus 로고
    • Methylation status of the reelin promoter region in the brain of schizophrenic patients
    • Tochigi M., Iwamoto K., Bundo M., Komori B., Sasaki T., Kato N., and Kato T. Methylation status of the reelin promoter region in the brain of schizophrenic patients. Biol. Psychiatry 63 (2008) 530-533
    • (2008) Biol. Psychiatry , vol.63 , pp. 530-533
    • Tochigi, M.1    Iwamoto, K.2    Bundo, M.3    Komori, B.4    Sasaki, T.5    Kato, N.6    Kato, T.7
  • 12
    • 33646247628 scopus 로고    scopus 로고
    • The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression
    • Dempster E.L., Mill J., Craig I.W., and Collier D.A. The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression. BMC Med. Genet. 7 (2006) 10
    • (2006) BMC Med. Genet. , vol.7 , pp. 10
    • Dempster, E.L.1    Mill, J.2    Craig, I.W.3    Collier, D.A.4
  • 13
    • 0034054736 scopus 로고    scopus 로고
    • Disease-specific alterations in frontal cortex brain proteins in schizophrenia, bipolar disorder, and major depressive disorder. The Stanley Neuropathology Consortium
    • Johnston-Wilson N.L., Sims C.D., Hofmann J.P., Anderson L., Shore A.D., Torrey E.F., and Yolken R.H. Disease-specific alterations in frontal cortex brain proteins in schizophrenia, bipolar disorder, and major depressive disorder. The Stanley Neuropathology Consortium. Mol. Psychiatry 5 (2000) 142-149
    • (2000) Mol. Psychiatry , vol.5 , pp. 142-149
    • Johnston-Wilson, N.L.1    Sims, C.D.2    Hofmann, J.P.3    Anderson, L.4    Shore, A.D.5    Torrey, E.F.6    Yolken, R.H.7
  • 15
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y., and Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. Roy. Statist. Soc. Ser. B. Methodological 57 (1995) 289-300
    • (1995) J. Roy. Statist. Soc. Ser. B. Methodological , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 16
    • 34347395711 scopus 로고    scopus 로고
    • Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages
    • Craddock N., and Owen M.J. Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages. World Psychiatry 6 (2007) 20-27
    • (2007) World Psychiatry , vol.6 , pp. 20-27
    • Craddock, N.1    Owen, M.J.2
  • 17
    • 33745012299 scopus 로고    scopus 로고
    • Modularity and community structure in networks
    • Newman M.E. Modularity and community structure in networks. Proc. Natl. Acad. Sci. USA 103 (2006) 8577-8582
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 8577-8582
    • Newman, M.E.1
  • 18
    • 27844521293 scopus 로고    scopus 로고
    • A shrinkage approach to large-scale covariance matrix estimation and implications for functional genomics
    • Article32
    • Schafer J., and Strimmer K. A shrinkage approach to large-scale covariance matrix estimation and implications for functional genomics. Stat. Appl. Genet. Mol. Biol. 4 (2005) Article32
    • (2005) Stat. Appl. Genet. Mol. Biol. , vol.4
    • Schafer, J.1    Strimmer, K.2
  • 19
    • 0242266622 scopus 로고    scopus 로고
    • Eukaryotic RNase P: role of RNA and protein subunits of a primordial catalytic ribonucleoprotein in RNA-based catalysis
    • Mann H., Ben-Asouli Y., Schein A., Moussa S., and Jarrous N. Eukaryotic RNase P: role of RNA and protein subunits of a primordial catalytic ribonucleoprotein in RNA-based catalysis. Mol. Cell 12 (2003) 925-935
    • (2003) Mol. Cell , vol.12 , pp. 925-935
    • Mann, H.1    Ben-Asouli, Y.2    Schein, A.3    Moussa, S.4    Jarrous, N.5
  • 20
    • 1442349704 scopus 로고    scopus 로고
    • Review: the Kell, Duffy, and Kidd blood group systems
    • Westhoff C.M., and Reid M.E. Review: the Kell, Duffy, and Kidd blood group systems. Immunohematol. 20 (2004) 37-49
    • (2004) Immunohematol. , vol.20 , pp. 37-49
    • Westhoff, C.M.1    Reid, M.E.2
  • 22
    • 0027394890 scopus 로고
    • Methylation-sensitive DNA binding by v-myb and c-myb proteins
    • Klempnauer K.H. Methylation-sensitive DNA binding by v-myb and c-myb proteins. Oncogene 8 (1993) 111-115
    • (1993) Oncogene , vol.8 , pp. 111-115
    • Klempnauer, K.H.1
  • 23
    • 0037370442 scopus 로고    scopus 로고
    • Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site
    • Maier H., Colbert J., Fitzsimmons D., Clark D.R., and Hagman J. Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site. Mol. Cell. Biol. 23 (2003) 1946-1960
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 1946-1960
    • Maier, H.1    Colbert, J.2    Fitzsimmons, D.3    Clark, D.R.4    Hagman, J.5
  • 24
    • 33644877079 scopus 로고    scopus 로고
    • Uroplakin Ib gene transcription in urothelial tumor cells is regulated by CpG methylation
    • Cowled P., Kanter I., Leonardos L., and Jackson P. Uroplakin Ib gene transcription in urothelial tumor cells is regulated by CpG methylation. Neoplasia 7 (2005) 1091-1103
    • (2005) Neoplasia , vol.7 , pp. 1091-1103
    • Cowled, P.1    Kanter, I.2    Leonardos, L.3    Jackson, P.4
  • 26
    • 4644228386 scopus 로고    scopus 로고
    • The GABA-glutamate connection in schizophrenia: which is the proximate cause?
    • Coyle J.T. The GABA-glutamate connection in schizophrenia: which is the proximate cause?. Biochem. Pharmacol. 68 (2004) 1507-1514
    • (2004) Biochem. Pharmacol. , vol.68 , pp. 1507-1514
    • Coyle, J.T.1
  • 27
    • 0035007327 scopus 로고    scopus 로고
    • GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder
    • Benes F.M., and Berretta S. GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology 25 (2001) 1-27
    • (2001) Neuropsychopharmacology , vol.25 , pp. 1-27
    • Benes, F.M.1    Berretta, S.2
  • 28
    • 34249099711 scopus 로고    scopus 로고
    • NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders
    • Lau C.G., and Zukin R.S. NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders. Nat. Rev. Neurosci. 8 (2007) 413-426
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 413-426
    • Lau, C.G.1    Zukin, R.S.2
  • 29
    • 22544449233 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia
    • Gupta D.S., McCullumsmith R.E., Beneyto M., Haroutunian V., Davis K.L., and Meador-Woodruff J.H. Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia. Synapse 57 (2005) 123-131
    • (2005) Synapse , vol.57 , pp. 123-131
    • Gupta, D.S.1    McCullumsmith, R.E.2    Beneyto, M.3    Haroutunian, V.4    Davis, K.L.5    Meador-Woodruff, J.H.6
  • 31
    • 11844304923 scopus 로고    scopus 로고
    • Decreased expression of vesicular glutamate transporter 1 and complexin II mRNAs in schizophrenia: further evidence for a synaptic pathology affecting glutamate neurons
    • Eastwood S.L., and Harrison P.J. Decreased expression of vesicular glutamate transporter 1 and complexin II mRNAs in schizophrenia: further evidence for a synaptic pathology affecting glutamate neurons. Schizophr. Res. 73 (2005) 159-172
    • (2005) Schizophr. Res. , vol.73 , pp. 159-172
    • Eastwood, S.L.1    Harrison, P.J.2
  • 32
    • 0035903814 scopus 로고    scopus 로고
    • Vesicular glutamate transporter transcript expression in the thalamus in schizophrenia
    • Smith R.E., Haroutunian V., Davis K.L., and Meador-Woodruff J.H. Vesicular glutamate transporter transcript expression in the thalamus in schizophrenia. Neuroreport 12 (2001) 2885-2887
    • (2001) Neuroreport , vol.12 , pp. 2885-2887
    • Smith, R.E.1    Haroutunian, V.2    Davis, K.L.3    Meador-Woodruff, J.H.4
  • 35
    • 34447331043 scopus 로고    scopus 로고
    • A microarray gene expression study of the molecular pharmacology of lithium carbonate on mouse brain mRNA to understand the neurobiology of mood stabilization and treatment of bipolar affective disorder
    • McQuillin A., Rizig M., and Gurling H.M. A microarray gene expression study of the molecular pharmacology of lithium carbonate on mouse brain mRNA to understand the neurobiology of mood stabilization and treatment of bipolar affective disorder. Pharmacogenet. Genomics 17 (2007) 605-617
    • (2007) Pharmacogenet. Genomics , vol.17 , pp. 605-617
    • McQuillin, A.1    Rizig, M.2    Gurling, H.M.3
  • 38
    • 34548163305 scopus 로고    scopus 로고
    • Helt determines GABAergic over glutamatergic neuronal fate by repressing Ngn genes in the developing mesencephalon
    • Nakatani T., Minaki Y., Kumai M., and Ono Y. Helt determines GABAergic over glutamatergic neuronal fate by repressing Ngn genes in the developing mesencephalon. Development 134 (2007) 2783-2793
    • (2007) Development , vol.134 , pp. 2783-2793
    • Nakatani, T.1    Minaki, Y.2    Kumai, M.3    Ono, Y.4
  • 39
    • 0033609561 scopus 로고    scopus 로고
    • Increased expression of Wnt-1 in schizophrenic brains
    • Miyaoka T., Seno H., and Ishino H. Increased expression of Wnt-1 in schizophrenic brains. Schizophr. Res. 38 (1999) 1-6
    • (1999) Schizophr. Res. , vol.38 , pp. 1-6
    • Miyaoka, T.1    Seno, H.2    Ishino, H.3
  • 40
    • 33646524277 scopus 로고    scopus 로고
    • Reduction of dopamine-related transcription factors Nurr1 and NGFI-B in the prefrontal cortex in schizophrenia and bipolar disorders
    • Xing G., Zhang L., Russell S., and Post R. Reduction of dopamine-related transcription factors Nurr1 and NGFI-B in the prefrontal cortex in schizophrenia and bipolar disorders. Schizophr. Res. 84 (2006) 36-56
    • (2006) Schizophr. Res. , vol.84 , pp. 36-56
    • Xing, G.1    Zhang, L.2    Russell, S.3    Post, R.4
  • 41
    • 0036294383 scopus 로고    scopus 로고
    • Chronic antipsychotic drug treatment induces long-lasting expression of fos and jun family genes and activator protein 1 complex in the rat prefrontal cortex
    • Kontkanen O., Lakso M., Wong G., and Castren E. Chronic antipsychotic drug treatment induces long-lasting expression of fos and jun family genes and activator protein 1 complex in the rat prefrontal cortex. Neuropsychopharmacology 27 (2002) 152-162
    • (2002) Neuropsychopharmacology , vol.27 , pp. 152-162
    • Kontkanen, O.1    Lakso, M.2    Wong, G.3    Castren, E.4
  • 42
    • 0034833743 scopus 로고    scopus 로고
    • Learning impairments and motor dysfunctions in adult Lhx5-deficient mice displaying hippocampal disorganization
    • Paylor R., Zhao Y., Libbey M., Westphal H., and Crawley J.N. Learning impairments and motor dysfunctions in adult Lhx5-deficient mice displaying hippocampal disorganization. Physiol. Behav. 73 (2001) 781-792
    • (2001) Physiol. Behav. , vol.73 , pp. 781-792
    • Paylor, R.1    Zhao, Y.2    Libbey, M.3    Westphal, H.4    Crawley, J.N.5
  • 43
  • 44
    • 0038724908 scopus 로고    scopus 로고
    • Molecular cloning and characterization of human RAI1, a gene associated with schizophrenia
    • Toulouse A., Rochefort D., Roussel J., Joober R., and Rouleau G.A. Molecular cloning and characterization of human RAI1, a gene associated with schizophrenia. Genomics 82 (2003) 162-171
    • (2003) Genomics , vol.82 , pp. 162-171
    • Toulouse, A.1    Rochefort, D.2    Roussel, J.3    Joober, R.4    Rouleau, G.A.5
  • 46
    • 0037376939 scopus 로고    scopus 로고
    • Gender differences in schizophrenia
    • Hafner H. Gender differences in schizophrenia. Psychoneuroendocrinology 28 Suppl 2 (2003) 17-54
    • (2003) Psychoneuroendocrinology , vol.28 , Issue.SUPPL. 2 , pp. 17-54
    • Hafner, H.1
  • 47
    • 0141732137 scopus 로고    scopus 로고
    • Gender differences in bipolar disorder
    • Arnold L.M. Gender differences in bipolar disorder. Psychiatr. Clin. North Am. 26 (2003) 595-620
    • (2003) Psychiatr. Clin. North Am. , vol.26 , pp. 595-620
    • Arnold, L.M.1
  • 48
    • 33847095134 scopus 로고    scopus 로고
    • Complex disease, gender and epigenetics
    • Kaminsky Z., Wang S.C., and Petronis A. Complex disease, gender and epigenetics. Ann. Med. 38 (2006) 530-544
    • (2006) Ann. Med. , vol.38 , pp. 530-544
    • Kaminsky, Z.1    Wang, S.C.2    Petronis, A.3
  • 49
    • 0344599272 scopus 로고
    • Genomic sequencing reveals a positive correlation between the kinetics of strand-specific DNA demethylation of the overlapping estradiol/glucocorticoid-receptor binding sites and the rate of avian vitellogenin mRNA synthesis
    • Saluz H.P., Jiricny J., and Jost J.P. Genomic sequencing reveals a positive correlation between the kinetics of strand-specific DNA demethylation of the overlapping estradiol/glucocorticoid-receptor binding sites and the rate of avian vitellogenin mRNA synthesis. Proc. Natl. Acad. Sci. USA 83 (1986) 7167-7171
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 7167-7171
    • Saluz, H.P.1    Jiricny, J.2    Jost, J.P.3
  • 50
    • 0028966928 scopus 로고
    • Sexually dimorphic DNA demethylation in the promoter of the Slp (sex-limited protein) gene in mouse liver
    • Yokomori N., Moore R., and Negishi M. Sexually dimorphic DNA demethylation in the promoter of the Slp (sex-limited protein) gene in mouse liver. Proc. Natl. Acad. Sci. USA 92 (1995) 1302-1306
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1302-1306
    • Yokomori, N.1    Moore, R.2    Negishi, M.3
  • 51
    • 2942741016 scopus 로고    scopus 로고
    • Schizophrenia as a manifestation of X-linked Mcleod-Neuroacanthocytosis syndrome
    • Jung H.H., and Haker H. Schizophrenia as a manifestation of X-linked Mcleod-Neuroacanthocytosis syndrome. J. Clin. Psychiatry 65 (2004) 722-723
    • (2004) J. Clin. Psychiatry , vol.65 , pp. 722-723
    • Jung, H.H.1    Haker, H.2
  • 52
    • 15744400492 scopus 로고    scopus 로고
    • Clozapine and the mitogen-activated protein kinase signal transduction pathway: implications for antipsychotic actions
    • Browning J.L., Patel T., Brandt P.C., Young K.A., Holcomb L.A., and Hicks P.B. Clozapine and the mitogen-activated protein kinase signal transduction pathway: implications for antipsychotic actions. Biol. Psychiatry 57 (2005) 617-623
    • (2005) Biol. Psychiatry , vol.57 , pp. 617-623
    • Browning, J.L.1    Patel, T.2    Brandt, P.C.3    Young, K.A.4    Holcomb, L.A.5    Hicks, P.B.6
  • 54
    • 0037199968 scopus 로고    scopus 로고
    • Hierarchical organization of modularity in metabolic networks
    • Ravasz E., Somera A.L., Mongru D.A., Oltvai Z.N., and Barabasi A.L. Hierarchical organization of modularity in metabolic networks. Science 297 (2002) 1551-1555
    • (2002) Science , vol.297 , pp. 1551-1555
    • Ravasz, E.1    Somera, A.L.2    Mongru, D.A.3    Oltvai, Z.N.4    Barabasi, A.L.5
  • 55
    • 0037417817 scopus 로고    scopus 로고
    • Modular organization of cellular networks
    • Rives A.W., and Galitski T. Modular organization of cellular networks. Proc. Natl. Acad. Sci. USA 100 (2003) 1128-1133
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1128-1133
    • Rives, A.W.1    Galitski, T.2
  • 56
    • 0142059836 scopus 로고    scopus 로고
    • Protein complexes and functional modules in molecular networks
    • Spirin V., and Mirny L.A. Protein complexes and functional modules in molecular networks. Proc. Natl. Acad. Sci. USA 100 (2003) 12123-12128
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 12123-12128
    • Spirin, V.1    Mirny, L.A.2
  • 57
    • 33646369393 scopus 로고    scopus 로고
    • Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band
    • Frigola J., Song J., Stirzaker C., Hinshelwood R.A., Peinado M.A., and Clark S.J. Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band. Nat. Genet. 38 (2006) 540-549
    • (2006) Nat. Genet. , vol.38 , pp. 540-549
    • Frigola, J.1    Song, J.2    Stirzaker, C.3    Hinshelwood, R.A.4    Peinado, M.A.5    Clark, S.J.6
  • 60
    • 1642433144 scopus 로고    scopus 로고
    • An association between variants in the IGF2 gene and Beckwith-Wiedemann syndrome: interaction between genotype and epigenotype
    • Murrell A., Heeson S., Cooper W.N., Douglas E., Apostolidou S., Moore G.E., Maher E.R., and Reik W. An association between variants in the IGF2 gene and Beckwith-Wiedemann syndrome: interaction between genotype and epigenotype. Hum. Mol. Genet. 13 (2004) 247-255
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 247-255
    • Murrell, A.1    Heeson, S.2    Cooper, W.N.3    Douglas, E.4    Apostolidou, S.5    Moore, G.E.6    Maher, E.R.7    Reik, W.8
  • 62
    • 23044514626 scopus 로고    scopus 로고
    • Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
    • Weber M., Davies J.J., Wittig D., Oakeley E.J., Haase M., Lam W.L., and Schubeler D. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat. Genet. 37 (2005) 853-862
    • (2005) Nat. Genet. , vol.37 , pp. 853-862
    • Weber, M.1    Davies, J.J.2    Wittig, D.3    Oakeley, E.J.4    Haase, M.5    Lam, W.L.6    Schubeler, D.7
  • 63
    • 2442424419 scopus 로고    scopus 로고
    • Germline epimutation of MLH1 in individuals with multiple cancers
    • Suter C.M., Martin D.I., and Ward R.L. Germline epimutation of MLH1 in individuals with multiple cancers. Nat. Genet. 36 (2004) 497-501
    • (2004) Nat. Genet. , vol.36 , pp. 497-501
    • Suter, C.M.1    Martin, D.I.2    Ward, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.