The influence of anthracosis and p16ink4a gene aberrant methylation on small-sized pulmonary adenocarcinoma

Experimental and Molecular Pathology

Volumn 90, Issue 1, 2011, Pages 131-136

  Wang, Daye ^a   Wang, Jue ^a   Li, Yong ^a   He, Zhili ^b   Zhang, Yong ^c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Aberrant methylation; Anthracosis; P16ink4a gene; Small sized pulmonary adenocarcinoma

Indexed keywords

BISULFITE; CYCLIN DEPENDENT KINASE INHIBITOR 2A;

ADULT; ADVANCED CANCER; AGED; ANTHRACOSIS; ARTICLE; CANCER CLASSIFICATION; CANCER SIZE; CANCER STAGING; CIGARETTE SMOKING; CONTROLLED STUDY; DNA METHYLATION; FEMALE; FOREIGN BODY; GENE FREQUENCY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LUNG ADENOCARCINOMA; LUNG PARENCHYMA; MAJOR CLINICAL STUDY; MALE; P16INK4A GENE; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE; ADENOCARCINOMA; COMPARATIVE STUDY; GENETICS; LUNG TUMOR; METABOLISM; MIDDLE AGED; PATHOLOGY; POLYMERASE CHAIN REACTION;

ADENOCARCINOMA; AGED; AGED, 80 AND OVER; ANTHRACOSIS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA METHYLATION; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION;

EID: 78650703071     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2010.10.014     Document Type: Article

References (14)

1. Diagnosis of diseases of the chest 1999, Saunders, Philadelphia, PA. 4th ed. R.S. Fraser, N.L. Müller, N. Colman, P.D. Paré (Eds.).
2. Herman J.G., Graff J.R., Myohanen S., et al. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc. Natl Acad. Sci. USA 1996, 93:9821-9826.
3. Hou M., Morishita Y., Iijima T., et al. The implication of anthracosis in the development of pulmonary adenocarcinoma. Jpn J. Cancer Res. 1998, 89:1251-1256.
4. Kim Y.T., Park S.J., Lee S.H., et al. Prognostic implication of aberrant promoter hypermethylation of CpG islands in adenocarcinoma of the lung. J. Thorac. Cardiovasc. Surg. 2005, 130(5):1378.
5. Lyon C.M., Klinge D.M., Liechty K.C., et al. Radiation-induced lung adenocarcinoma is associated with increased frequency of genes inactivated by promoter hypermethylation. Radiat. Res. 2007, 168(4):409-414.
6. Mirsadraee M., Saeedi P. Anthracosis of lung: evaluation of potential underlying causes. J. Bronchol. 2005, 12(2):84-87.
7. Noguchi M., Morikawa A., Kawasaki M., et al. Small adenocarcinoma of the lung. Histologic characteristics and prognosis. Cancer 1995, 75(12):2844-2852.
8. Shiba M., Kohno H., Kakizawa K., et al. Ki-67 immunostaining and other prognostic factors including tobacco smoking in patients with resected nonsmall cell lung carcinoma. Cancer 2000, 89:1457-1465.
9. Shimosato Y., Noguchi M. Pulmonary Neoplasms. Sternberg's diagnostic surgical pathology 2004, 1173-1222. Lippincott Williams & Wilkins, Philadelphia, PA. 4th ed. E.M. Stacey, C. Darryl (Eds.).
10. Suter C.M., Norrie M., Ku S.L., et al. CpG island methylation is a common finding in colorectal cancer cell lines. Br. J. Cancer 2003, 88(3):413-419.
11. Tanaka R., Wang D., Morishita Y., et al. Loss of function of p16 gene and prognosis of pulmonary adenocarcinoma. Cancer 2005, 103(3):608-615.
12. Thun A.J., Lally C.A., Flannery J.T., et al. Cigarette smoking and changes in the histopathology of lung cancer. J. Natl Cancer Inst. 1997, 89:1580-1586.
13. Toyooka S., Suzuki M., Maruyama R., et al. The relationship between aberrant methylation and survival in non-small-cell lung cancers. Br. J. Cancer 2004, 91(4):771-774.
14. Wang D., Minami Y., Shu Y., et al. The implication of background anthracosis in the development and progression of pulmonary adenocarcinoma. Cancer Sci. 2003, 94(8):707-711.