Effect of trichloroethylene and its metabolites, dichloroacetic acid and trichloroacetic acid, on the methylation and expression of c-Jun and c-Myc protooncogenes in mouse liver: Prevention by methionine

Toxicological Sciences

Volumn 54, Issue 2, 2000, Pages 399-407

  Tao, Lianhui ^a   Yang, Siming ^a   Xie, Mi ^a   Kramer, Paula M ^a   Pereira, Michael A ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

c jun; c myc; Dichloroacetic acid; DNA methylation; Methionine; mRNA expression; Protooncogenes; Trichloroacetic acid; Trichloroethylene

Indexed keywords

DICHLOROACETIC ACID; METHIONINE; STRESS ACTIVATED PROTEIN KINASE; TRICHLOROACETIC ACID; TRICHLOROETHYLENE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; DNA METHYLATION; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; FEMALE; GENE EXPRESSION; LIVER; METABOLITE; MOUSE; NONHUMAN; ONCOGENE C MYC; PROTO ONCOGENE;

ANIMALIA;

EID: 0034071060     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/54.2.399     Document Type: Article

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