메뉴 건너뛰기




Volumn 458, Issue 2, 2011, Pages 221-229

Alterations in the tumor suppressor gene p16 INK4A are associated with aggressive behavior of penile carcinomas

Author keywords

HPV; LOH; Metastasis; p16; Penile carcinoma

Indexed keywords

MONOCLONAL ANTIBODY; PROTEIN P16; PROTEIN P53; VIRUS DNA;

EID: 79951727256     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-010-1007-4     Document Type: Article
Times cited : (76)

References (40)
  • 1
    • 33750030758 scopus 로고    scopus 로고
    • The Regulation of INK4/ARF in Cancer and Aging
    • DOI 10.1016/j.cell.2006.10.003, PII S0092867406012840
    • WY Kim NE Sharpless 2006 The regulation of INK4/ARF in cancer and aging Cell 127 265 275 1:CAS:528:DC%2BD28XhtFOkt73M 10.1016/j.cell.2006.10.003 17055429 (Pubitemid 44572384)
    • (2006) Cell , vol.127 , Issue.2 , pp. 265-275
    • Kim, W.Y.1    Sharpless, N.E.2
  • 2
    • 0034660892 scopus 로고    scopus 로고
    • The pezcoller lecture: Cancer cell cycles revisited
    • CJ Sherr 2000 The Pezcoller lecture: cancer cell cycles revisited Cancer Res 60 3689 3695 1:CAS:528:DC%2BD3cXlt1Gksbs%3D 10919634 (Pubitemid 32204552)
    • (2000) Cancer Research , vol.60 , Issue.14 , pp. 3689-3695
    • Sherr, C.J.1
  • 3
    • 59349121140 scopus 로고    scopus 로고
    • Papillomaviruses in the causation of human cancers-a brief historical account
    • 1:CAS:528:DC%2BD1MXhs1ejt7Y%3D 10.1016/j.virol.2008.11.046 19135222
    • H zur Hausen 2009 Papillomaviruses in the causation of human cancers-a brief historical account Virology 384 260 265 1:CAS:528:DC%2BD1MXhs1ejt7Y%3D 10.1016/j.virol.2008.11.046 19135222
    • (2009) Virology , vol.384 , pp. 260-265
    • Zur Hausen, H.1
  • 4
    • 0026475319 scopus 로고
    • The causal link between human papillomavirus and invasive cervical cancer: A population-based case-control study in Colombia and Spain
    • 1:STN:280:DyaK3s%2Flt1ylsw%3D%3D 10.1002/ijc.2910520513 1330933
    • N Munoz FX Bosch S de Sanjose L Tafur I Izarzugaza M Gili P Viladiu C Navarro C Martos N Ascunce, et al. 1992 The causal link between human papillomavirus and invasive cervical cancer: a population-based case-control study in Colombia and Spain Int J Cancer 52 743 749 1:STN:280: DyaK3s%2Flt1ylsw%3D%3D 10.1002/ijc.2910520513 1330933
    • (1992) Int J Cancer , vol.52 , pp. 743-749
    • Munoz, N.1    Bosch, F.X.2    De Sanjose, S.3    Tafur, L.4    Izarzugaza, I.5    Gili, M.6    Viladiu, P.7    Navarro, C.8    Martos, C.9    Ascunce, N.10
  • 6
    • 0034795914 scopus 로고    scopus 로고
    • Detection and typing of human papillomavirus DNA in penile carcinoma: Evidence for multiple independent pathways of penile carcinogenesis
    • MA Rubin B Kleter M Zhou G Ayala AL Cubilla WG Quint EC Pirog 2001 Detection and typing of human papillomavirus DNA in penile carcinoma: evidence for multiple independent pathways of penile carcinogenesis Am J Pathol 159 1211 1218 1:CAS:528:DC%2BD3MXnvVCnt7w%3D 10.1016/S0002-9440(10)62506-0 11583947 (Pubitemid 32947950)
    • (2001) American Journal of Pathology , vol.159 , Issue.4 , pp. 1211-1218
    • Rubin, M.A.1    Kleter, B.2    Zhou, M.3    Ayala, G.4    Cubilla, A.L.5    Quint, W.G.V.6    Pirog, E.C.7
  • 8
    • 46749142939 scopus 로고    scopus 로고
    • Detection of HPV-DNA, p53 alterations, and methylation in penile squamous cell carcinoma in Japanese men
    • DOI 10.1111/j.1440-1827.2008.02259.x
    • N Yanagawa M Osakabe M Hayashi G Tamura T Motoyama 2008 Detection of HPV-DNA, p53 alterations, and methylation in penile squamous cell carcinoma in Japanese men Pathol Int 58 477 482 1:CAS:528:DC%2BD1cXhtVOnurbE 10.1111/j.1440-1827.2008.02259.x 18705766 (Pubitemid 351952022)
    • (2008) Pathology International , vol.58 , Issue.8 , pp. 477-482
    • Yanagawa, N.1    Osakabe, M.2    Hayashi, M.3    Tamura, G.4    Motoyama, T.5
  • 9
    • 0141515537 scopus 로고    scopus 로고
    • INK4A/cyclin D/Rb pathway in penile carcinoma, one of which is mediated by high-risk human papillomavirus
    • DOI 10.1002/path.1394
    • E Ferreux AP Lont S Horenblas MPW Gallee FM Raaphorst DM von Knebel CJLM Meijer PJF Snijders 2003 Evidence for at least three alternative mechanisms targeting the p16INK4A/Cyclin D/Rb pathway in penile carcinoma, one of which is mediated by high-risk human papillomavirus J Pathol 201 109 118 1:CAS:528:DC%2BD3sXotFyqsL0%3D 10.1002/path.1394 12950023 (Pubitemid 37121209)
    • (2003) Journal of Pathology , vol.201 , Issue.1 , pp. 109-118
    • Ferreux, E.1    Lont, A.P.2    Horenblas, S.3    Gallee, M.P.W.4    Raaphorst, F.M.5    Von Knebel Doeberitz, M.6    Meijer, C.J.L.M.7    Snijders, P.J.F.8
  • 10
    • 34548761447 scopus 로고    scopus 로고
    • Screening of microsatellite markers in penile cancer reveals differences between metastatic and nonmetastatic carcinomas
    • DOI 10.1038/modpathol.3800931, PII 3800931
    • M Poetsch B-J Schuart G Schwesinger B Kleist C Protzel 2007 Screening of microsatellite markers in penile cancer reveals differences between metastatic and non-metastatic carcinomas Mod Pathol 20 1069 1077 1:CAS:528: DC%2BD2sXhtVCku7%2FI 10.1038/modpathol.3800931 17690710 (Pubitemid 47429195)
    • (2007) Modern Pathology , vol.20 , Issue.10 , pp. 1069-1077
    • Poetsch, M.1    Schuart, B.-J.2    Schwesinger, G.3    Kleist, B.4    Protzel, C.5
  • 12
    • 0035870248 scopus 로고    scopus 로고
    • A gene hypermethylation profile of human cancer
    • M Esteller PF Corn SB Baylin JG Herman 2001 A gene hypermethylation profile of human cancer Cancer Res 61 3225 3229 1:CAS:528:DC%2BD3MXjtFSjt7g%3D 11309270 (Pubitemid 32695003)
    • (2001) Cancer Research , vol.61 , Issue.8 , pp. 3225-3229
    • Esteller, M.1    Corn, P.G.2    Baylin, S.B.3    Herman, J.G.4
  • 15
    • 33751228705 scopus 로고    scopus 로고
    • False-positive lesions detected by fluorescence cystoscopy: Any association with p53 and p16 expression?
    • DOI 10.1007/s00345-006-0109-8
    • K Hendricksen PM Moonen AG der Heijden JA Witjes 2006 False-positive lesions detected by fluorescence cystoscopy: any association with p53 and p16 expression? World J Urol 24 597 601 1:CAS:528:DC%2BD28Xht1WrtL7N 10.1007/s00345-006-0109-8 17021825 (Pubitemid 44782314)
    • (2006) World Journal of Urology , vol.24 , Issue.5 , pp. 597-601
    • Hendricksen, K.1    Moonen, P.M.J.2    Heijden, A.G.3    Witjes, J.A.4
  • 16
    • 33845942433 scopus 로고    scopus 로고
    • p16INK4A immunohistochemistry is superior to HPV in situ hybridization for the detection of high-risk HPV in atypical squamous metaplasia
    • DOI 10.1097/01.pas.0000213347.65014.ee, PII 0000047820070100000004
    • CS Kong BL Balzer ML Troxell BK Patterson TA Longacre 2007 p16INK4A immunohistochemistry is superior to HPV in situ hybridization for the detection of high-risk HPV in atypical squamous metaplasia Am J Surg Pathol 31 33 43 10.1097/01.pas.0000213347.65014.ee 17197917 (Pubitemid 46036900)
    • (2007) American Journal of Surgical Pathology , vol.31 , Issue.1 , pp. 33-43
    • Kong, C.S.1    Balzer, B.L.2    Troxell, M.L.3    Patterson, B.K.4    Longacre, T.A.5
  • 17
    • 77950292941 scopus 로고    scopus 로고
    • Pancreatic acinar cell carcinomas with prominent ductal differentiation: Mixed acinar ductal carcinoma and mixed acinar endocrine ductal carcinoma
    • 10.1097/PAS.0b013e3181cfcac7 20182344
    • EB Stelow R Shaco-Levy F Bao J Garcia DS Klimstra 2010 Pancreatic acinar cell carcinomas with prominent ductal differentiation: mixed acinar ductal carcinoma and mixed acinar endocrine ductal carcinoma Am J Surg Pathol. 34 510 518 10.1097/PAS.0b013e3181cfcac7 20182344
    • (2010) Am J Surg Pathol. , vol.34 , pp. 510-518
    • Stelow, E.B.1    Shaco-Levy, R.2    Bao, F.3    Garcia, J.4    Klimstra, D.S.5
  • 18
    • 0035074472 scopus 로고    scopus 로고
    • PTEN/MMAC1 in malignant melanoma and its importance for tumor progression
    • DOI 10.1016/S0165-4608(00)00353-8, PII S0165460800003538
    • M Poetsch T Dittberner C Woenckhaus 2001 PTEN/MMAC1 in malignant melanoma and its importance for tumour progression Cancer Genet Cytogenet 125 21 26 1:CAS:528:DC%2BD3MXisF2ltbk%3D 10.1016/S0165-4608(00)00353-8 11297763 (Pubitemid 32288768)
    • (2001) Cancer Genetics and Cytogenetics , vol.125 , Issue.1 , pp. 21-26
    • Poetsch, M.1    Dittberner, T.2    Woenckhaus, C.3
  • 19
    • 23244460708 scopus 로고    scopus 로고
    • Loss of heterozygosity occurs predominantly, but not exclusively, in the epithelial compartment of pleomorphic adenoma
    • DOI 10.1593/neo.05163
    • M Poetsch A Zimmermann E Wolf B Kleist 2005 Loss of heterozygosity occurs predominantly, but not exclusively in the epithelial compartment of pleomorphic adenoma Neoplasia 7 688 695 10.1593/neo.05163 16026648 (Pubitemid 41099422)
    • (2005) Neoplasia , vol.7 , Issue.7 , pp. 688-695
    • Poetsch, M.1    Zimmermann, A.2    Wolf, E.3    Kleist, B.4
  • 21
    • 0036162726 scopus 로고    scopus 로고
    • Detection of new PTEN/MMAC1 mutations in head and neck squamous cell carcinomas with loss of chromosome 10
    • DOI 10.1016/S0165-4608(01)00509-X, PII S016546080100509X
    • M Poetsch G Lorenz B Kleist 2002 Detection of new PTEN/MMAC1 mutations in head and neck squamous cell carcinomas with loss of chromosomes 10 Cancer Genet Cytogenet 132 20 24 1:CAS:528:DC%2BD38XktFWlsQ%3D%3D 10.1016/S0165-4608(01) 00509-X 11801303 (Pubitemid 34136045)
    • (2002) Cancer Genetics and Cytogenetics , vol.132 , Issue.1 , pp. 20-24
    • Poetsch, M.1    Lorenz, G.2    Kleist, B.3
  • 22
    • 33947588546 scopus 로고    scopus 로고
    • Prognosis in patients with hepatocellular carcinoma correlates to mutations of p53 and/or hMSH2 genes
    • DOI 10.1016/j.ejca.2007.01.032, PII S0959804907001207
    • M Yano K Hamatani H Eguchi Y Hirai DG MacPhee K Sugino K Dohi T Itamoto T Asahara 2007 Prognosis in patients with hepatocellular carcinoma correlates to mutations of p53 and/or hMSH2 genes Eur J Cancer 43 1092 1100 1:CAS:528:DC%2BD2sXjslGnurs%3D 10.1016/j.ejca.2007.01.032 17350822 (Pubitemid 46483040)
    • (2007) European Journal of Cancer , vol.43 , Issue.6 , pp. 1092-1100
    • Yano, M.1    Hamatani, K.2    Eguchi, H.3    Hirai, Y.4    MacPhee, D.G.5    Sugino, K.6    Dohi, K.7    Itamoto, T.8    Asahara, T.9
  • 23
    • 33646427172 scopus 로고    scopus 로고
    • Aberrant promoter methylation of p16 and MGMT genes in lung tumors from smoking and never-smoking lung cancer patients
    • 1:CAS:528:DC%2BD28XovVKltLY%3D 10.1593/neo.05586 16533425
    • Y Liu Q Lan JM Siegfried JD Luketich P Keohavong 2006 Aberrant promoter methylation of p16 and MGMT genes in lung tumors from smoking and never-smoking lung cancer patients Neoplasia 8 46 51 1:CAS:528:DC%2BD28XovVKltLY%3D 10.1593/neo.05586 16533425
    • (2006) Neoplasia , vol.8 , pp. 46-51
    • Liu, Y.1    Lan, Q.2    Siegfried, J.M.3    Luketich, J.D.4    Keohavong, P.5
  • 24
    • 38349104527 scopus 로고    scopus 로고
    • Human papillomavirus-associated increase in p16INK4A expression in penile lichen sclerosus and squamous cell carcioma
    • 1:STN:280:DC%2BD1c7mtF2quw%3D%3D 10.1111/j.1365-2133.2007.08305.x 18047520
    • DM Prowse EN Ktori D Chandrasekaran A Prapa S Baithun 2008 Human papillomavirus-associated increase in p16INK4A expression in penile lichen sclerosus and squamous cell carcioma Br J Dermatol 158 261 265 1:STN:280:DC%2BD1c7mtF2quw%3D%3D 10.1111/j.1365-2133.2007.08305.x 18047520
    • (2008) Br J Dermatol , vol.158 , pp. 261-265
    • Prowse, D.M.1    Ktori, E.N.2    Chandrasekaran, D.3    Prapa, A.4    Baithun, S.5
  • 26
  • 28
    • 77951457224 scopus 로고    scopus 로고
    • Comparison of human papillomavirus in situ hybridization and p16 immunohistochemistry in the detection of human papillomavirus-associated head and neck cancer based on a prospective clinical experience
    • 20186832
    • AD Singhi WH Westra 2010 Comparison of human papillomavirus in situ hybridization and p16 immunohistochemistry in the detection of human papillomavirus-associated head and neck cancer based on a prospective clinical experience Cancer 116 2166 2173 20186832
    • (2010) Cancer , vol.116 , pp. 2166-2173
    • Singhi, A.D.1    Westra, W.H.2
  • 30
    • 43049145895 scopus 로고    scopus 로고
    • Diagnostic utility of p16INK4a: A reappraisal of its use in cervical biopsies
    • DOI 10.1080/00313020802035907, PII 792733524
    • INK4a: a reappraisal of its use in cervical biopsies Pathology 40 335 344 1:CAS:528:DC%2BD1cXlsV2qsrw%3D 10.1080/00313020802035907 18446622 (Pubitemid 351630885)
    • (2008) Pathology , vol.40 , Issue.4 , pp. 335-344
    • Mulvany, N.J.1    Allen, D.G.2    Wilson, S.M.3
  • 31
    • 33645978442 scopus 로고    scopus 로고
    • INK4a is not correlated with HPV status in CIN 1
    • 1:STN:280:DC%2BD283lslyjtQ%3D%3D 10.1111/j.1365-2559.2006.02340.x 16681697
    • INK4a is not correlated with HPV status in CIN 1 Histopathology 48 767 1:STN:280:DC%2BD283lslyjtQ%3D%3D 10.1111/j.1365-2559.2006. 02340.x 16681697
    • (2006) Histopathology , vol.48 , pp. 767
    • Galmiche, L.1    Coste-Burel, M.2    Lopez, P.3    Phillippe, H.J.4    Laboisse, C.5
  • 32
    • 65549091469 scopus 로고    scopus 로고
    • Detection of human papillomavirus and cellular regulators p16INK4a, p53, and NF.kappaB in penile cancer cases in Kenya
    • 1:CAS:528:DC%2BD1MXmtlajt7o%3D 10.4149/av-2009-01-43 19301950
    • M Senba N Buziba N Mori A Wada S Irie K Toriyama 2009 Detection of human papillomavirus and cellular regulators p16INK4a, p53, and NF.kappaB in penile cancer cases in Kenya Acta Virol 53 43 48 1:CAS:528:DC%2BD1MXmtlajt7o%3D 10.4149/av-2009-01-43 19301950
    • (2009) Acta Virol , vol.53 , pp. 43-48
    • Senba, M.1    Buziba, N.2    Mori, N.3    Wada, A.4    Irie, S.5    Toriyama, K.6
  • 33
    • 77949450418 scopus 로고    scopus 로고
    • Human papillomavirus, p16 and p53 expression associated with survival of head and neck cancer
    • 10.1186/1750-9378-5-4 20181227
    • EM Smith LM Rubenstein H Hoffman TH Haugen LP Turek 2010 Human papillomavirus, p16 and p53 expression associated with survival of head and neck cancer Infect Agent Cancer 5 4 10.1186/1750-9378-5-4 20181227
    • (2010) Infect Agent Cancer , vol.5 , pp. 4
    • Smith, E.M.1    Rubenstein, L.M.2    Hoffman, H.3    Haugen, T.H.4    Turek, L.P.5
  • 34
    • 77957582721 scopus 로고    scopus 로고
    • Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: A retrospective analysis of biomarkers in matched primary tumor and lymph node metastases
    • 1:CAS:528:DC%2BC3cXht1KnsLrO 10.1002/cncr.25304 20572035
    • E Karamitopoulou I Zlober A Koumarianou ES Patsouris G Peros A Lugli 2010 Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases Cancer 116 4474 4486 1:CAS:528:DC%2BC3cXht1KnsLrO 10.1002/cncr.25304 20572035
    • (2010) Cancer , vol.116 , pp. 4474-4486
    • Karamitopoulou, E.1    Zlober, I.2    Koumarianou, A.3    Patsouris, E.S.4    Peros, G.5    Lugli, A.6
  • 35
    • 46349107398 scopus 로고    scopus 로고
    • Inducible re-expression of p16 in an orthotopic mouse model of pancreatic cancer inhibits lymphangiogenesis and lymphatic metastasis
    • DOI 10.1038/sj.bjc.6604457, PII 6604457
    • P Schulz A Scholz A Rexin P Hauff M Schirner B Wiedenmann K Detjen 2008 Inducible re-expression of p16 in an orthotopic mouse model of pancreatic cancer inhibits lymphangiogenesis and lymphatic metastasis Br J Cancer 99 110 117 1:CAS:528:DC%2BD1cXnvFeqsLw%3D 10.1038/sj.bjc.6604457 18577984 (Pubitemid 351920244)
    • (2008) British Journal of Cancer , vol.99 , Issue.1 , pp. 110-117
    • Schulz, P.1    Scholz, A.2    Rexin, A.3    Hauff, P.4    Schirner, M.5    Wiedenmann, B.6    Detjen, K.7
  • 36
    • 0036286368 scopus 로고    scopus 로고
    • p53 as a new prognostic factor for lymph node metastasis in penile carcinoma: Analysis of 82 patients treated with amputation and bilateral lymphadenectomy
    • A Lopes AL Bezerra CA Pinto SV Serrano CA de Mello LL Villa 2002 p53 as a new prognostic factor for lymph node metastasis in penile carcinoma: analysis of 82 patients treated with amputation and bilateral lymphadenectomy J Urol 168 81 86 10.1016/S0022-5347(05)64836-7 12050497 (Pubitemid 34640788)
    • (2002) Journal of Urology , vol.168 , Issue.1 , pp. 81-86
    • Lopes, A.1    Bezerra, A.L.R.2    Antonio, C.3    Pinto, L.4    Serrano, S.V.5    De Mello, C.A.6    Villa, L.L.7
  • 37
    • 0036136460 scopus 로고    scopus 로고
    • Immunoexpression of p53 protein and proliferating cell nuclear antigen in penile carcinoma
    • 1:CAS:528:DC%2BD38Xjsl2gtw%3D%3D 10.1016/S0022-5347(05)65389-X 11743282
    • AC Martins SM Faria AJ Cologna HJ Suaid S Tucci Jr 2002 Immunoexpression of p53 protein and proliferating cell nuclear antigen in penile carcinoma J Urol 167 89 93 1:CAS:528:DC%2BD38Xjsl2gtw%3D%3D 10.1016/S0022-5347(05)65389-X 11743282
    • (2002) J Urol , vol.167 , pp. 89-93
    • Martins, A.C.1    Faria, S.M.2    Cologna, A.J.3    Suaid, H.J.4    Tucci Jr., S.5
  • 38
    • 0032503494 scopus 로고    scopus 로고
    • Human papillomavirus DNA and p53 status in penile carcinomas
    • DOI 10.1002/(SICI)1097-0215(19980610)76:6<779::AID-IJC1>3.0.CO;2-V
    • JE Levi P Rahal AS Sarkis L Villa 1998 Human papillomarvirus DNA and p53 status in penile carcinomas Int J Cancer 76 779 783 1:CAS:528:DyaK1cXjsFyiurs%3D 10.1002/(SICI)1097-0215(19980610)76:6<779::AID-IJC1>3.0.CO;2-V 9626339 (Pubitemid 28262091)
    • (1998) International Journal of Cancer , vol.76 , Issue.6 , pp. 779-783
    • Levi, J.E.1    Rahal, P.2    Sakkis, A.S.3    Villa, L.L.4
  • 40
    • 77953815362 scopus 로고    scopus 로고
    • P53 immunohistochemistry in bladder cancer-a new approach to an old question
    • 1:CAS:528:DC%2BC3cXotVWks7g%3D 20610276
    • PJ Goebell SG Groshen BJ Schmitz-Drager 2010 p53 immunohistochemistry in bladder cancer-a new approach to an old question Urol Oncol 28 377 388 1:CAS:528:DC%2BC3cXotVWks7g%3D 20610276
    • (2010) Urol Oncol , vol.28 , pp. 377-388
    • Goebell, P.J.1    Groshen, S.G.2    Schmitz-Drager, B.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.