Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis

Gastroenterology

Volumn 139, Issue 6, 2010, Pages 1855-1864

  Baba, Yoshifumi ^a   Nosho, Katsuhiko ^a   Shima, Kaori ^a   Huttenhower, Curtis ^b   Tanaka, Noriko ^a,b   Hazra, Aditi ^a,b   Giovannucci, Edward L ^a,b   Fuchs, Charles S ^a   Ogino, Shuji ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Clinical Outcome; Epigenetics; Imprinting Control Region; Therapeutic Target

Indexed keywords

B RAF KINASE; BISULFITE; K RAS PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; SOMATOMEDIN B;

AGED; ARTICLE; CANCER SURVIVAL; CLINICAL ASSESSMENT; COLORECTAL CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; CPG ISLAND; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIFFERENTIALLY METHYLATED REGION; DISEASE ASSOCIATION; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PYROSEQUENCING;

EID: 78649693873     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2010.07.050     Document Type: Article

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