메뉴 건너뛰기




Volumn 46, Issue 10, 2010, Pages 734-739

P16INK4A promoter hypermethylation is associated with invasiveness and prognosis of oral squamous cell carcinoma in an age-dependent manner

Author keywords

Age dependent; DNA methylation; Metastasis; Oral squamous cell carcinoma; p16INK4A; Quantitative methylation specific PCR

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; DEATH ASSOCIATED PROTEIN KINASE; GLUTATHIONE TRANSFERASE P1; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; UVOMORULIN;

EID: 77957376763     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2010.07.002     Document Type: Article
Times cited : (53)

References (36)
  • 2
    • 20444381307 scopus 로고    scopus 로고
    • Betel-quid and areca-nut chewing and some areca-nut-derived nitrosamines
    • International Agency for Research on Cancer
    • International Agency for Research on Cancer. Betel-quid and areca-nut chewing and some areca-nut-derived nitrosamines. IARC Monographs on the evaluation of carcinogenic risks to humans; 2004. p. 85.
    • (2004) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , pp. 85
  • 4
    • 77949775196 scopus 로고    scopus 로고
    • Surgical outcomes and prognostic factors of oral cancer associated with betel quid chewing and tobacco smoking in Taiwan
    • S.Y. Liu, C.L. Lu, C.T. Chiou, C.Y. Yen, G.A. Liaw, and Y.C. Chen Surgical outcomes and prognostic factors of oral cancer associated with betel quid chewing and tobacco smoking in Taiwan Oral Oncol 46 4 2010 276 282
    • (2010) Oral Oncol , vol.46 , Issue.4 , pp. 276-282
    • Liu, S.Y.1    Lu, C.L.2    Chiou, C.T.3    Yen, C.Y.4    Liaw, G.A.5    Chen, Y.C.6
  • 5
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • M. Esteller Cancer epigenomics: DNA methylomes and histone-modification maps Nat Rev Genet 8 4 2007 286 298
    • (2007) Nat Rev Genet , vol.8 , Issue.4 , pp. 286-298
    • Esteller, M.1
  • 6
    • 0038576158 scopus 로고    scopus 로고
    • The power and the promise of DNA methylation markers
    • P.W. Laird The power and the promise of DNA methylation markers Nat Rev Cancer 3 4 2003 253 266
    • (2003) Nat Rev Cancer , vol.3 , Issue.4 , pp. 253-266
    • Laird, P.W.1
  • 7
    • 77950801864 scopus 로고    scopus 로고
    • Identification of hypermethylated genes associated with cisplatin resistance in human cancers
    • X. Chang, C.L. Monitto, S. Demokan, M.S. Kim, S.S. Chang, and X. Zhong Identification of hypermethylated genes associated with cisplatin resistance in human cancers Cancer Res 70 7 2010 2870 2879
    • (2010) Cancer Res , vol.70 , Issue.7 , pp. 2870-2879
    • Chang, X.1    Monitto, C.L.2    Demokan, S.3    Kim, M.S.4    Chang, S.S.5    Zhong, X.6
  • 8
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • P.A. Jones, and S.B. Baylin The fundamental role of epigenetic events in cancer Nat Rev Genet 3 6 2002 415 428
    • (2002) Nat Rev Genet , vol.3 , Issue.6 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 9
    • 29244469466 scopus 로고    scopus 로고
    • The epigenetic progenitor origin of human cancer
    • A.P. Feinberg, R. Ohlsson, and S. Henikoff The epigenetic progenitor origin of human cancer Nat Rev Genet 7 1 2006 21 33
    • (2006) Nat Rev Genet , vol.7 , Issue.1 , pp. 21-33
    • Feinberg, A.P.1    Ohlsson, R.2    Henikoff, S.3
  • 10
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction?
    • S.B. Baylin, and J.E. Ohm Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 6 2 2006 107 116
    • (2006) Nat Rev Cancer , vol.6 , Issue.2 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 11
    • 33750030758 scopus 로고    scopus 로고
    • The regulation of INK4/ARF in cancer and aging
    • W.Y. Kim, and N.E. Sharpless The regulation of INK4/ARF in cancer and aging Cell 127 2 2006 265 275
    • (2006) Cell , vol.127 , Issue.2 , pp. 265-275
    • Kim, W.Y.1    Sharpless, N.E.2
  • 12
    • 0032767550 scopus 로고    scopus 로고
    • Differential DNA methylation of the p16 INK4A/CDKN2A promoter in human oral cancer cells and normal human oral keratinocytes
    • D.T. Cody II, Y. Huang, C.J. Darby, G.K. Johnson, and F.E. Domann Differential DNA methylation of the p16 INK4A/CDKN2A promoter in human oral cancer cells and normal human oral keratinocytes Oral Oncol 35 5 1999 516 522
    • (1999) Oral Oncol , vol.35 , Issue.5 , pp. 516-522
    • Cody II, D.T.1    Huang, Y.2    Darby, C.J.3    Johnson, G.K.4    Domann, F.E.5
  • 13
    • 0030708545 scopus 로고    scopus 로고
    • Methylation, a major mechanism of p16/CDKN2 gene inactivation in head and neck squamous carcinoma
    • A.K. El-Naggar, S. Lai, G. Clayman, J.K. Lee, M.A. Luna, and H. Goepfert Methylation, a major mechanism of p16/CDKN2 gene inactivation in head and neck squamous carcinoma Am J Pathol 151 6 1997 1767 1774
    • (1997) Am J Pathol , vol.151 , Issue.6 , pp. 1767-1774
    • El-Naggar, A.K.1    Lai, S.2    Clayman, G.3    Lee, J.K.4    Luna, M.A.5    Goepfert, H.6
  • 14
    • 49249139883 scopus 로고    scopus 로고
    • High frequency of hypermethylation of p14, p15 and p16 in oral pre-cancerous lesions associated with betel-quid chewing in Sri Lanka
    • M. Takeshima, M. Saitoh, K. Kusano, H. Nagayasu, Y. Kurashige, and M. Malsantha High frequency of hypermethylation of p14, p15 and p16 in oral pre-cancerous lesions associated with betel-quid chewing in Sri Lanka J Oral Pathol Med 37 8 2008 475 479
    • (2008) J Oral Pathol Med , vol.37 , Issue.8 , pp. 475-479
    • Takeshima, M.1    Saitoh, M.2    Kusano, K.3    Nagayasu, H.4    Kurashige, Y.5    Malsantha, M.6
  • 15
    • 54049086674 scopus 로고    scopus 로고
    • P16 promoter methylation is a potential predictor of malignant transformation in oral epithelial dysplasia
    • G.L. Hall, R.J. Shaw, E.A. Field, S.N. Rogers, D.N. Sutton, and J.A. Woolgar p16 promoter methylation is a potential predictor of malignant transformation in oral epithelial dysplasia Cancer Epidemiol Biomarkers Prev 17 8 2008 2174 2179
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , Issue.8 , pp. 2174-2179
    • Hall, G.L.1    Shaw, R.J.2    Field, E.A.3    Rogers, S.N.4    Sutton, D.N.5    Woolgar, J.A.6
  • 16
    • 69349084287 scopus 로고    scopus 로고
    • Methylation of p16 CpG island associated with malignant progression of oral epithelial dysplasia: A prospective cohort study
    • J. Cao, J. Zhou, Y. Gao, L. Gu, H. Meng, and H. Liu Methylation of p16 CpG island associated with malignant progression of oral epithelial dysplasia: a prospective cohort study Clin Cancer Res 15 16 2009 5178 5183
    • (2009) Clin Cancer Res , vol.15 , Issue.16 , pp. 5178-5183
    • Cao, J.1    Zhou, J.2    Gao, Y.3    Gu, L.4    Meng, H.5    Liu, H.6
  • 17
    • 0034652596 scopus 로고    scopus 로고
    • Gene promoter hypermethylation in tumors and serum of head and neck cancer patients
    • M. Sanchez-Cespedes, M. Esteller, L. Wu, H. Nawroz-Danish, G.H. Yoo, and W.M. Koch Gene promoter hypermethylation in tumors and serum of head and neck cancer patients Cancer Res 60 4 2000 892 895
    • (2000) Cancer Res , vol.60 , Issue.4 , pp. 892-895
    • Sanchez-Cespedes, M.1    Esteller, M.2    Wu, L.3    Nawroz-Danish, H.4    Yoo, G.H.5    Koch, W.M.6
  • 18
    • 2942620221 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase gene: Epigenetic silencing and prognostic value in head and neck squamous cell carcinoma
    • 6-methylguanine-DNA methyltransferase gene: epigenetic silencing and prognostic value in head and neck squamous cell carcinoma Cancer Epidemiol Biomarkers Prev 13 6 2004 967 975
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , Issue.6 , pp. 967-975
    • Zuo, C.1    Ai, L.2    Ratliff, P.3    Suen, J.Y.4    Hanna, E.5    Brent, T.P.6
  • 19
    • 0348049993 scopus 로고    scopus 로고
    • Concurrent hypermethylation of multiple regulatory genes in chewing tobacco associated oral squamous cell carcinomas and adjacent normal tissues
    • V. Kulkarni, and D. Saranath Concurrent hypermethylation of multiple regulatory genes in chewing tobacco associated oral squamous cell carcinomas and adjacent normal tissues Oral Oncol 40 2 2004 145 153
    • (2004) Oral Oncol , vol.40 , Issue.2 , pp. 145-153
    • Kulkarni, V.1    Saranath, D.2
  • 20
    • 54049101143 scopus 로고    scopus 로고
    • Hypermethylation of E-cadherin is an independent predictor of improved survival in head and neck squamous cell carcinoma
    • C.J. Marsit, M.R. Posner, M.D. McClean, and K.T. Kelsey Hypermethylation of E-cadherin is an independent predictor of improved survival in head and neck squamous cell carcinoma Cancer 113 7 2008 1566 1571
    • (2008) Cancer , vol.113 , Issue.7 , pp. 1566-1571
    • Marsit, C.J.1    Posner, M.R.2    McClean, M.D.3    Kelsey, K.T.4
  • 21
    • 33947239430 scopus 로고    scopus 로고
    • Tumor-specific methylation in saliva: A promising biomarker for early detection of head and neck cancer recurrence
    • C.A. Righini, F. de Fraipont, J.F. Timsit, C. Faure, E. Brambilla, and E. Reyt Tumor-specific methylation in saliva: a promising biomarker for early detection of head and neck cancer recurrence Clin Cancer Res 13 4 2007 1179 1185
    • (2007) Clin Cancer Res , vol.13 , Issue.4 , pp. 1179-1185
    • Righini, C.A.1    De Fraipont, F.2    Timsit, J.F.3    Faure, C.4    Brambilla, E.5    Reyt, E.6
  • 22
    • 70449592332 scopus 로고    scopus 로고
    • Gene hypermethylation in tumor tissue of advanced oral squamous cell carcinoma patients
    • G. Supic, R. Kozomara, M. Brankovic-Magic, N. Jovic, and Z. Magic Gene hypermethylation in tumor tissue of advanced oral squamous cell carcinoma patients Oral Oncol 45 12 2009 1051 1057
    • (2009) Oral Oncol , vol.45 , Issue.12 , pp. 1051-1057
    • Supic, G.1    Kozomara, R.2    Brankovic-Magic, M.3    Jovic, N.4    Magic, Z.5
  • 23
    • 34548090762 scopus 로고    scopus 로고
    • Differential DNA methylation associated with hepatitis B virus infection in hepatocellular carcinoma
    • P.F. Su, T.C. Lee, P.J. Lin, P.H. Lee, Y.M. Jeng, and C.H. Chen Differential DNA methylation associated with hepatitis B virus infection in hepatocellular carcinoma Int J Cancer 121 6 2007 1257 1264
    • (2007) Int J Cancer , vol.121 , Issue.6 , pp. 1257-1264
    • Su, P.F.1    Lee, T.C.2    Lin, P.J.3    Lee, P.H.4    Jeng, Y.M.5    Chen, C.H.6
  • 25
  • 26
    • 38749124349 scopus 로고    scopus 로고
    • INK4A genetic and epigenetic profiles differ in relation to age and site in head and neck squamous cell carcinomas
    • INK4A genetic and epigenetic profiles differ in relation to age and site in head and neck squamous cell carcinomas Hum Pathol 39 3 2008 452 458
    • (2008) Hum Pathol , vol.39 , Issue.3 , pp. 452-458
    • O'Regan, E.M.1    Toner, M.E.2    Finn, S.P.3    Fan, C.Y.4    Ring, M.5    Hagmar, B.6
  • 27
    • 0033178714 scopus 로고    scopus 로고
    • Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas
    • H. Harada, K. Nakagawa, S. Iwata, M. Saito, Y. Kumon, and S. Sakaki Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas Cancer Res 59 15 1999 3783 3789
    • (1999) Cancer Res , vol.59 , Issue.15 , pp. 3783-3789
    • Harada, H.1    Nakagawa, K.2    Iwata, S.3    Saito, M.4    Kumon, Y.5    Sakaki, S.6
  • 28
    • 0030726538 scopus 로고    scopus 로고
    • Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro
    • S.K. Chintala, J. Fueyo, C. Gomez-Manzano, B. Venkaiah, R. Bjerkvig, and W.K. Yung Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro Oncogene 15 17 1997 2049 2057
    • (1997) Oncogene , vol.15 , Issue.17 , pp. 2049-2057
    • Chintala, S.K.1    Fueyo, J.2    Gomez-Manzano, C.3    Venkaiah, B.4    Bjerkvig, R.5    Yung, W.K.6
  • 29
    • 46349107398 scopus 로고    scopus 로고
    • Inducible re-expression of p16 in an orthotopic mouse model of pancreatic cancer inhibits lymphangiogenesis and lymphatic metastasis
    • P. Schulz, A. Scholz, A. Rexin, P. Hauff, M. Schirner, and B. Wiedenmann Inducible re-expression of p16 in an orthotopic mouse model of pancreatic cancer inhibits lymphangiogenesis and lymphatic metastasis Br J Cancer 99 1 2008 110 117
    • (2008) Br J Cancer , vol.99 , Issue.1 , pp. 110-117
    • Schulz, P.1    Scholz, A.2    Rexin, A.3    Hauff, P.4    Schirner, M.5    Wiedenmann, B.6
  • 30
    • 0037442417 scopus 로고    scopus 로고
    • Inhibition of colon tumor progression and angiogenesis by the Ink4a/Arf locus
    • S.L. Gibson, C.Y. Dai, H.-W. Lee, R.A. DePinho, M.S. Gee, and W.M.F. Lee Inhibition of colon tumor progression and angiogenesis by the Ink4a/Arf locus Cancer Res 63 4 2003 742 746
    • (2003) Cancer Res , vol.63 , Issue.4 , pp. 742-746
    • Gibson, S.L.1    Dai, C.Y.2    Lee, H.-W.3    Depinho, R.A.4    Gee, M.S.5    Lee, W.M.F.6
  • 31
    • 48149104562 scopus 로고    scopus 로고
    • P16INK4A gene promoter hypermethylation in mucosa as a prognostic factor for patients with colorectal cancer
    • Y. Wettergren, E. Odin, S. Nilsson, G. Carlsson, and B. Gustavsson p16INK4A gene promoter hypermethylation in mucosa as a prognostic factor for patients with colorectal cancer Mol Med 14 7-8 2008 412 421
    • (2008) Mol Med , vol.14 , Issue.78 , pp. 412-421
    • Wettergren, Y.1    Odin, E.2    Nilsson, S.3    Carlsson, G.4    Gustavsson, B.5
  • 32
    • 13944260728 scopus 로고    scopus 로고
    • Stromal-epithelial interactions in aging and cancer: Senescent fibroblasts alter epithelial cell differentiation
    • S. Parrinello, J.-P. Coppe, A. Krtolica, and J. Campisi Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation J Cell Sci 118 3 2005 485 496
    • (2005) J Cell Sci , vol.118 , Issue.3 , pp. 485-496
    • Parrinello, S.1    Coppe, J.-P.2    Krtolica, A.3    Campisi, J.4
  • 33
    • 58149235288 scopus 로고    scopus 로고
    • Areca-treated fibroblasts enhance tumorigenesis of oral epithelial cells
    • H.H. Lu, C.J. Liu, T.Y. Liu, S.Y. Kao, S.C. Lin, and K.W. Chang Areca-treated fibroblasts enhance tumorigenesis of oral epithelial cells J Dent Res 87 11 2008 1069 1074
    • (2008) J Dent Res , vol.87 , Issue.11 , pp. 1069-1074
    • Lu, H.H.1    Liu, C.J.2    Liu, T.Y.3    Kao, S.Y.4    Lin, S.C.5    Chang, K.W.6
  • 34
    • 0037142615 scopus 로고    scopus 로고
    • Patterns of gene promoter methylation in squamous cell cancer of the head and neck
    • M. Hasegawa, H.H. Nelson, E. Peters, E. Ringstrom, M. Posner, and K.T. Kelsey Patterns of gene promoter methylation in squamous cell cancer of the head and neck Oncogene 21 27 2002 4231 4236
    • (2002) Oncogene , vol.21 , Issue.27 , pp. 4231-4236
    • Hasegawa, M.1    Nelson, H.H.2    Peters, E.3    Ringstrom, E.4    Posner, M.5    Kelsey, K.T.6
  • 36
    • 0037427808 scopus 로고    scopus 로고
    • Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer
    • S. Toyooka, R. Maruyama, K.O. Toyooka, D. McLerran, Z. Feng, and Y. Fukuyama Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer Int J Cancer 103 2 2003 153 160
    • (2003) Int J Cancer , vol.103 , Issue.2 , pp. 153-160
    • Toyooka, S.1    Maruyama, R.2    Toyooka, K.O.3    McLerran, D.4    Feng, Z.5    Fukuyama, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.