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We apologize to colleagues whose work could not be cited because of space limitations. We thank members of the Moazed and Grewal laboratories for helpful discussions, and L. Pile, J. Landry, A. Verdel, and members of the Grewal laboratory for their comments on the manuscript. Work in the authors' laboratories is supported by the NCI (S.I.S.G.), the NIH (D.M.), and the Ellison Medical Foundation (S.I.S.G. and D.H.).
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