The reduced expression and aberrant methylation of p16INK4a in chromate workers with lung cancer

Lung Cancer

Volumn 53, Issue 3, 2006, Pages 295-302

  Kondo, Kazuya ^a   Takahashi, Yuji ^a   Hirose, Yukiko ^a   Nagao, Taeko ^a   Tsuyuguchi, Masaru ^b   Hashimoto, Masato ^c   Ochiai, Atsushi ^d   Monden, Yasumasa ^a   Tangoku, Akira ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b TOKUSHIMA PREFECTURAL CENTRAL HOSPITAL   (Japan)

^c Iwamizawa Rousai Hospital   (Japan)

^d NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Carcinogenesis; Chromium; Lung cancer; Methylation; p16 gene; Protein expression

Indexed keywords

CARCINOGEN; CHROMIC ACID; GENE PRODUCT; PROTEIN P16INK4A;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; FEMALE; GENE FREQUENCY; GENE REPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INDUSTRIAL WORKER; INHALATION; LUNG CANCER; LUNG CARCINOGENESIS; MALE; OCCUPATIONAL CANCER; OCCUPATIONAL EXPOSURE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SMOKING;

ADULT; AGED; CHROMATES; CHROMIUM; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; OCCUPATIONAL EXPOSURE; SULFITES;

EID: 33746916117     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2006.05.022     Document Type: Article

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