H3K27 trimethylation is an early epigenetic event of p16INK4a silencing for regaining tumorigenesis in fusion reprogrammed hepatoma cells

Journal of Biological Chemistry

Volumn 285, Issue 24, 2010, Pages 18828-18837

  Yao, Jia Yi ^a,b   Zhang, Lei ^b   Zhang, Xin ^a,b   He, Zhi Ying ^a   Ma, Yue ^c   Wang, Li Jian HuiXin ^b,d   Hu, Yi Ping ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^c INSTITUTE OF BIOPHYSICS   (China)

^d UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MODEL; CELL-CYCLE ARREST; DNA METHYLATION; EPIGENETIC REGULATION; EPIGENETIC SILENCING; GENE EXPRESSION PATTERNS; HEPATOCELLULAR; HEPATOCELLULAR CARCINOMA; HEPATOMA CELLS; HISTONE METHYLATION; MOUSE EMBRYONIC STEM CELLS; PROMOTER REGION; TRIMETHYLATION; TUMOR DEVELOPMENT; TUMORIGENESIS;

ALKYLATION; CELL PROLIFERATION; GENE EXPRESSION; METHYLATION; STRATEGIC PLANNING; TUMORS;

STEM CELLS;

CYCLIN DEPENDENT KINASE INHIBITOR 2A; DNA; HISTONE H3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; CHROMATIN; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; EMBRYONIC STEM CELL; EPIGENETICS; GENE EXPRESSION; GENE SILENCING; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN METHYLATION;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL DIFFERENTIATION; CELL LINE, TUMOR; CHROMATIN; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA METHYLATION; EMBRYONIC STEM CELLS; EPIGENESIS, GENETIC; FLOW CYTOMETRY; GENE SILENCING; HISTONES; LIVER NEOPLASMS; MICE;

EID: 77953301461     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.077974     Document Type: Article

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