Carcinogen exposure and gene promoter hypermethylation in bladder cancer

Carcinogenesis

Volumn 27, Issue 1, 2006, Pages 112-116

  Marsit, Carmen J ^a   Karagas, Margaret R ^b   Danaee, Hadi ^a   Liu, Mei ^a   Andrew, Angeline ^b   Schned, Alan ^b   Nelson, Heather H ^b   Kelsey, Karl T ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC; PROTEIN P16INK4A; PROTEIN PRSS3; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; TRYPSINOGEN; UNCLASSIFIED DRUG;

ADULT; ADVANCED CANCER; AGED; ARTICLE; BLADDER CANCER; BLADDER CARCINOGENESIS; BLADDER TUMOR; CANCER PATIENT; CANCER STAGING; CIGARETTE SMOKING; CONTROLLED STUDY; EPIGENETICS; FEMALE; GENE SILENCING; GENETIC ANALYSIS; GENETIC RISK; HUMAN; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; NAIL; POPULATION RESEARCH; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN METHYLATION; TOBACCO; TOE; TUMOR SUPPRESSOR GENE;

ADULT; AGED; ARSENIC; CARCINOMA, TRANSITIONAL CELL; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA METHYLATION; FEMALE; GENE SILENCING; GENOTYPE; HUMANS; MALE; MIDDLE AGED; NEW HAMPSHIRE; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); PROMOTER REGIONS, GENETIC; SMOKING; TRYPSIN; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; URINARY BLADDER NEOPLASMS;

EID: 29744460315     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgi172     Document Type: Article

References (35)

1. Jemal A. Murray T. Ward E. Samuels A. Tiwari R.C. Ghafoor A. Feuer E.J. and Thun M.J. (2005) Cancer statistics 2005. CA Cancer J. Clin. 55 10-30.
2. Silverman D. Morrison A. and Devesa S. (1996) Bladder cancer. In Schottenfeld D. and Fraumeni J.J. (eds) Cancer Epidemiology and Prevention. Oxford Universty Press New York NY pp. 1156-1179.
3. Vineis P. Kogevinas M. Simonato L. Brennan P. and Boffetta P. (2000) Levelling-off of the risk of lung and bladder cancer in heavy smokers: an analysis based on multicentric case-control studies and a metabolic interpretation. Mutat. Res. 463 103-10.
4. Vineis P. Marinelli D. Autrup H. et al. (2001) Current smoking occupation N-acetyltransferase-2 and bladder cancer: A pooled analysis of genotype-based studies. Cancer Epidemiol. Biomarkers Prev. 10 1249-1252.
5. Bates M.N. Smith A.H. and Cantor K.P. (1995) Case-control study of bladder cancer and arsenic in drinking water. Am. J. Epidemiol. 141 523-530.
6. Karagas M.R. Tosteson T.D. Morris J.S. Demidenko E. Mott L.A. Heaney J. and Schned A. (2004) Incidence of transitional cell carcinoma of the bladder and arsenic exposure in New Hampshire. Cancer Causes Control 15 465-472.
7. Hopenhayn-Rich C. Biggs M.L. Fuchs A. Bergoglio R. Tello E.E. Nicolli H. and Smith A.H. (1996) Bladder cancer mortality associated with arsenic in drinking water in Argentina. Epidemiology 7 117-124.
8. King W.D. and Marrett L.D. (1996) Case-control study of bladder cancer and chlorination by-products in treated water (Ontario Canada). Cancer Causes Control 7 596-604.
9. Wilkens L.R. Kadir M.M. Kolonel L.N. Nomura A.M. and Hankin J.H. (1996) Risk factors for lower urinary tract cancer: The role of total fluid consumption nitrites and nitrosamines and selected foods. Cancer Epidemiol. Biomarkers Prev. 5 161-166.
10. Sidransky D. Von Eschenbach A. Tsai Y.C. et al. (1991) Identification of p53 gene mutations in bladder cancers and urine samples. Science 252 706-709.
11. Kelsey K.T. Hirao T. Schned A. Hirao S. Devi-Ashok T. Nelson H.H. Andrew A. and Karagas M.R. (2004) A population-based study of immunohistochemical detection of p53 alteration in bladder cancer. Br. J. Cancer 90 1572-1576.
12. Chan M.W. Chan L.W. Tang N.L. et al. (2003) Frequent hypermethylation of promoter region of RASSF1A in tumor tissues and voided urine of urinary bladder cancer patients. Int. J. Cancer 104 611-616.
13. Maruyama R. Toyooka S. Toyooka K.O. et al. (2001) Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features. Cancer Res. 61 8659-8663.
14. Friedrich M.G. Weisenberger D.J. Cheng J.C. et al. (2004) Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients. Clin. Cancer Res. 10 7457-7465.
15. Chan M.W. Chan L.W. Tang N.L. et al. (2002) Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients. Clin. Cancer Res. 8 464-470.
16. Belinsky S.A. (2005) Silencing of genes by promoter hypermethylation: key event in rodent and human lung cancer. Carcinogenesis [Epub ahead of print] in press.
17. Toyooka S. Mamyama R. Toyooka K.O. et al. (2003) Smoke exposure histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer. Int. J. Cancer 103 153-160.
18. Kim D.H. Nelson H.H. Wiencke J.K. Zheng S. Christiani D.C. Wain J.C. Mark E.J. and Kelsey K.T. (2001) p16(INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer. Cancer Res. 61 3419-3424.
19. Marsit C.J. Kim D.H. Liu M. Hinds P.W. Wiencke J.K. Nelson H.H. and Kelsey K.T. (2005) Hypermethylation of RASSF1A and BLU tumor suppressor genes in non-small cell lung cancer: Implications for tobacco smoking during adolescence. Int. J. Cancer 114 219-223.
20. Kim D.H. Kim J.S. Ji Y.I. Shim Y.M. Kim H. Han J. and Park J. (2003) Hypermethylation of RASSF1A promoter is associated with the age at starting smoking and a poor prognosis in primary non-small cell lung cancer. Cancer Res. 63 3743-3746.
21. Marsit C.J. Okpukpara C. Danaee H. and Kelsey K.T. (2005) Epigenetic silencing of the PRSS3 putative tumor suppressor gene in non-small cell lung cancer. Mol. Carcinog. in press.
22. Rossman T.G. (2003) Mechanism of arsenic carcinogenesis: An integrated approach. Mutat. Res. 533 37-65.
23. Zhao C.Q. Young M.R. Diwan B.A. Coogan T.P. and Waalkes M.P. (1997) Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression. Proc. Natl Acad. Sci. USA 94 10907-10912.
24. Zhong C.X. and Mass M.J. (2001) Both hypomethylation and hypermethylation of DNA associated with arsenite exposure in cultures of human cells identified by methylation-sensitive arbitrarily-primed PCR. Toxicol. Lett. 122 223-234.
25. Mass M.J. and Wang L. (1997) Arsenic alters cytosine methylation patterns of the promoter of the tumor suppressor gene p53 in human lung cells: A model for a mechanism of carcinogenesis. Mutat. Res. 386 263-277.
26. Karagas M.R. Tosteson T.D. Blum J. Morris J.S. Baron J.A. and Klaue B. (1998) Design of an epidemiologic study of drinking water arsenic exposure and skin and bladder cancer risk in a U.S. population. Environ. Health Perspect. 106 1047-1050.
27. Karagas M.R. Tosteson T.D. Blum J. Klaue B. Weiss J.E. Stannard V. Spate V. and Morris J.S. (2000) Measurement of low levels of arsenic exposure: a comparison of water and toenail concentrations. Am. J. Epidemiol. 152 84-90.
28. Herman J.G. Graff J.R. Myohanen S. Nelkin B.D. and Baylin S.B. (1996) Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands. Proc. Natl Acad. Sci. USA 93 9821-9826.
29. van Engeland M. Roemen G.M. Brink M. Pachen M.M. Weijenberg M.P. de Bruine A.P. Arends J.W. van den Brandt P.A. de Goeij A.F. and Herman J.G. (2002) K-ras mutations and RASSF1A promoter methylation in colorectal cancer. Oncogene 21 3792-3795.
30. Yamashita K. Mimori K. Inoue H. Mori M. and Sidransky D. (2003) A tumor-suppressive role for trypsin in human cancer progression. Cancer Res. 63 6575-6578.
31. Eads C.A. Danenberg K.D. Kawakami K. Saltz L.B. Blake C. Shibata D. Danenberg P.V. and Laird P.W. (2000) MethyLight: A high-throughput assay to measure DNA methylation. Nucleic Acids Res. 28 E32.
32. Dallol A. Agathanggelou A. Fenton S.L. Ahmed-Choudhury J. Hesson L. Vos M.D. Clark G.J. Downward J. Maher E.R. and Latif F. (2004) RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics. Cancer Res. 64 4112-4116.
33. Okoji R.S. Yu R.C. Maronpot R.R. and Froines J.R. (2002) Sodium arsenite administration via drinking water increases genome-wide and Ha-ras DNA hypomethylation in methyl-deficient C57BL/6J mice. Carcinogenesis 23 777-785.
34. McDorman E.W. Collins B.W. and Allen J.W. (2002) Dietary folate deficiency enhances induction of micronuclei by arsenic in mice. Environ. Mol. Mutagen. 40 71-77.
35. Ehrlich M. (2002) DNA methylation in cancer: Too much but also too little. Oncogene 21 5400-5413.