Hypomethylation and overexpression of c-jun and c-myc protooncogenes and increased DNA methyltransferase activity in dichloroacetic and trichloroacetic acid-promoted mouse liver tumors

Cancer Letters

Volumn 158, Issue 2, 2000, Pages 185-193

  Tao, Lianhui ^a   Yang, Siming ^a   Xie, Mi ^a   Kramer, Paula M ^a   Pereira, Michael A ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

c myc; c jun; Dichloroacetic acid; DNA methylation; Mouse liver tumor; Trichloroacetic acid

Indexed keywords

DICHLOROACETIC ACID; DNA METHYLTRANSFERASE; MESSENGER RNA; TRICHLOROACETIC ACID;

ADOLESCENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; ENZYME ACTIVITY; FEMALE; GENE OVEREXPRESSION; IMMUNOBLOTTING; LIVER CARCINOGENESIS; LIVER TUMOR; MOUSE; NONHUMAN; ONCOGENE C JUN; ONCOGENE C MYC; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTO ONCOGENE; SOUTHERN BLOTTING;

ALKYLATING AGENTS; ANIMALS; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; BLOTTING, WESTERN; DICHLOROACETATE; DNA METHYLATION; DNA, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; LIVER NEOPLASMS, EXPERIMENTAL; METHYLNITROSOUREA; METHYLTRANSFERASES; MICE; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-JUN; PROTO-ONCOGENE PROTEINS C-MYC; RNA, MESSENGER; TRICHLOROACETIC ACID;

ANIMALIA;

EID: 0034308194     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(00)00518-8     Document Type: Article

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