DNA hypomethylation leads to elevated mutation rates

Nature

Volumn 395, Issue 6697, 1998, Pages 89-93

  Chen, Richard Z ^a   Pettersson, Ulf ^a,c,d   Beard, Caroline ^a,c,d   Jackson Grusby, Laurie ^a   Jaenisch, Rudolf ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c UPPSALA UNIVERSITY   (Sweden)

^d ARIAD PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLTRANSFERASE;

ARTICLE; CARCINOGENESIS; DNA METHYLATION; EMBRYO CELL; GENE DELETION; GENETIC STABILITY; MOUSE; MUTATION RATE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ANIMALS; BLOTTING, SOUTHERN; CELL LINE; DNA; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; HERPES SIMPLEX; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MALE; MICE; MICE, INBRED C57BL; MUTATION; POLYMERASE CHAIN REACTION; STEM CELLS; THYMIDINE KINASE;

EID: 0032480226     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/25779     Document Type: Article

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