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Volumn 31, Issue 4, 2009, Pages 407-419

Promoter methylation of P15INK4B gene is possibly associated with parvovirus B19 infection in adult acute leukemias

Author keywords

Acute leukemias; Epstein Barr virus; Methylation specific PCR; Myelodysplastic syndrome; P15INK4B gene promoter methylation; Parvovirus B19

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2B; VIRUS DNA;

EID: 67651108667     PISSN: 17515521     EISSN: 1751553X     Source Type: Journal    
DOI: 10.1111/j.1751-553X.2008.01052.x     Document Type: Article
Times cited : (15)

References (78)
  • 5
    • 0031035406 scopus 로고    scopus 로고
    • Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia
    • Batova A., Diccianni M.B., Yu J.C., Nobori T., Link M.P., Pullen J. Yu A.L. (1997) Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia. Cancer Research 57, 832 836.
    • (1997) Cancer Research , vol.57 , pp. 832-836
    • Batova, A.1    Diccianni, M.B.2    Yu, J.C.3    Nobori, T.4    Link, M.P.5    Pullen, J.6    Yu, A.L.7
  • 6
    • 31344466008 scopus 로고    scopus 로고
    • DNA methylation and gene silencing in cancer
    • -11
    • Baylin S.B. (2005) DNA methylation and gene silencing in cancer. Nature Clinical Practice Oncology 2 (Suppl. 1 S4 11.
    • (2005) Nature Clinical Practice Oncology , vol.2 , Issue.SUPPL. 1-S4
    • Baylin, S.B.1
  • 10
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. (2002) DNA methylation patterns and epigenetic memory. Genes & Development 16, 6 21.
    • (2002) Genes & Development , vol.16 , pp. 6-21
    • Bird, A.1
  • 13
    • 0035861985 scopus 로고    scopus 로고
    • A consensus DNA recognition motif for two KDWK transcription factors identifies flexible-length, CpG-methylation sensitive cognate binding sites in the majority of Human promoters
    • Burnett E., Christensen J. Tattersall P. (2001) A consensus DNA recognition motif for two KDWK transcription factors identifies flexible-length, CpG-methylation sensitive cognate binding sites in the majority of Human promoters. Journal of Molecular Biology 314, 1029 1039.
    • (2001) Journal of Molecular Biology , vol.314 , pp. 1029-1039
    • Burnett, E.1    Christensen, J.2    Tattersall, P.3
  • 14
    • 0036316318 scopus 로고    scopus 로고
    • Hypermethylation of the p15(INK4B) gene in acute leukemia and myelodysplastic syndromes
    • Chen H. Wu S. (2002) Hypermethylation of the p15(INK4B) gene in acute leukemia and myelodysplastic syndromes. Chinese Medical Journal 115, 987 990.
    • (2002) Chinese Medical Journal , vol.115 , pp. 987-990
    • Chen, H.1    Wu, S.2
  • 15
    • 0029143369 scopus 로고
    • Minute virus of mice transcriptional activator protein NS1 binds directly to the transactivation region of the viral P38 promoter in a strictly ATP-dependent manner
    • Christensen J., Cotmore S.F. Tattersall P. (1995) Minute virus of mice transcriptional activator protein NS1 binds directly to the transactivation region of the viral P38 promoter in a strictly ATP-dependent manner. Journal of Virology 69, 5422 5430.
    • (1995) Journal of Virology , vol.69 , pp. 5422-5430
    • Christensen, J.1    Cotmore, S.F.2    Tattersall, P.3
  • 16
    • 0030738386 scopus 로고    scopus 로고
    • Parvovirus initiation factor PIF: A novel human DNA-binding factor which coordinately recognizes two ACGT motifs
    • Christensen J., Cotmore S.F. Tattersall P. (1997) Parvovirus initiation factor PIF: a novel human DNA-binding factor which coordinately recognizes two ACGT motifs. Journal of Virology 1, 5733 5741.
    • (1997) Journal of Virology , vol.1 , pp. 5733-5741
    • Christensen, J.1    Cotmore, S.F.2    Tattersall, P.3
  • 17
    • 0141502199 scopus 로고    scopus 로고
    • Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia
    • Christiansen D.H., Andersen M.K. Pedersen-Bjergaard J. (2003) Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia. Leukemia 17, 1813 1819.
    • (2003) Leukemia , vol.17 , pp. 1813-1819
    • Christiansen, D.H.1    Andersen, M.K.2    Pedersen-Bjergaard, J.3
  • 18
    • 33846913745 scopus 로고    scopus 로고
    • DNA viruses in human cancer: An integrated overview on fundamental mechanisms of viral carcinogenesis
    • De Oliveira D.E. (2007) DNA viruses in human cancer: an integrated overview on fundamental mechanisms of viral carcinogenesis. Cancer Letters 247, 182 196.
    • (2007) Cancer Letters , vol.247 , pp. 182-196
    • De Oliveira, D.E.1
  • 19
    • 0142153982 scopus 로고    scopus 로고
    • Profiling aberrant DNA methylation in hematologic neoplasm: A view from the tip of the iceberg
    • Esteller M. (2003) Profiling aberrant DNA methylation in hematologic neoplasm: a view from the tip of the iceberg. Clinical Immunology 109, 80 88.
    • (2003) Clinical Immunology , vol.109 , pp. 80-88
    • Esteller, M.1
  • 20
    • 67651141808 scopus 로고    scopus 로고
    • Updates on DNA hypomethylation in the treatment of MDS
    • Garcia-Manero G. (2006) Updates on DNA hypomethylation in the treatment of MDS. Clinical Advances in Hematology & Oncology 4 (Suppl. 4 14 15.
    • (2006) Clinical Advances in Hematology & Oncology , vol.4 , Issue.SUPPL. 4 , pp. 14-15
    • Garcia-Manero, G.1
  • 22
    • 84928639100 scopus 로고    scopus 로고
    • Pathogenetic mechanisms underlying myelodysplastic syndromes
    • In. ed. Greenberg PL. pp. Cambridge University Press. Cambridge, England.
    • Greenberg P.L. (2006) Pathogenetic mechanisms underlying myelodysplastic syndromes. In : Myelodysplastic Syndromes. Clinical and Biological Advances (ed Greenberg PL pp. 63 93. Cambridge University Press, Cambridge, England.
    • (2006) Myelodysplastic Syndromes. Clinical and Biological Advances , pp. 63-93
    • Greenberg, P.L.1
  • 24
    • 0034797324 scopus 로고    scopus 로고
    • Transient pancytopenia preceding acute lymphoblastic leukaemia (pre-ALL) precipitated by parvovirus B19
    • Heegaard E.D., Madsen H.O. Schmiegelow K. (2001) Transient pancytopenia preceding acute lymphoblastic leukaemia (pre-ALL) precipitated by parvovirus B19. British Journal of Haematology 114, 810 813.
    • (2001) British Journal of Haematology , vol.114 , pp. 810-813
    • Heegaard, E.D.1    Madsen, H.O.2    Schmiegelow, K.3
  • 25
    • 0032983526 scopus 로고    scopus 로고
    • The role of parvovirus B19 infection in childhood acute lymphoblastic leukemia
    • DOI 10.1080/088800199277155
    • Heegaard E.D., Jensen L., Hornsleth A. Schmiegelow K. (1999) The role of parvovirus B19 infection in childhood acute lymphoblastic leukemia. Pediatric Hematology and Oncology 16, 329 334. (Pubitemid 29295774)
    • (1999) Pediatric Hematology and Oncology , vol.16 , Issue.4 , pp. 329-334
    • Heegaard, E.D.1    Jensen, L.2    Hornsleth, A.3    Schmiegelow, K.4
  • 26
    • 0032731581 scopus 로고    scopus 로고
    • Hypermethylation of tumor suppressor genes in cancer
    • Herman J.G. (1999) Hypermethylation of tumor suppressor genes in cancer. Seminars in Cancer Biology 9, 359 367.
    • (1999) Seminars in Cancer Biology , vol.9 , pp. 359-367
    • Herman, J.G.1
  • 27
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman J.G. Baylin S.B. (2003) Gene silencing in cancer in association with promoter hypermethylation. New England Journal of Medicine 349, 2042 2054.
    • (2003) New England Journal of Medicine , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 29
    • 0030046322 scopus 로고    scopus 로고
    • Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B
    • Herman J.G., Jen J., Merlo A. Baylin S.B. (1996b) Hypermethylation- associated inactivation indicates a tumor suppressor role for p15INK4B. Cancer Research 56, 722 727.
    • (1996) Cancer Research , vol.56 , pp. 722-727
    • Herman, J.G.1    Jen, J.2    Merlo, A.3    Baylin, S.B.4
  • 30
    • 0031025368 scopus 로고    scopus 로고
    • Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies
    • Herman J.G., Civin C.I., Issa J.P., Collector M.I., Sharkis S.J. Baylin S.B. (1997) Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies. Cancer Research 57, 837 841.
    • (1997) Cancer Research , vol.57 , pp. 837-841
    • Herman, J.G.1    Civin, C.I.2    Issa, J.P.3    Collector, M.I.4    Sharkis, S.J.5    Baylin, S.B.6
  • 31
    • 0036000273 scopus 로고    scopus 로고
    • The absence of the p15INK4B gene alterations in adult patients with precursor B-cell acute lymphoblastic leukaemia is a favourable prognostic factor
    • Hoshino K., Asou N., Okubo T., Suzushima H., Kiyokawa T., Kawano F. Mitsuya H. (2002) The absence of the p15INK4B gene alterations in adult patients with precursor B-cell acute lymphoblastic leukaemia is a favourable prognostic factor. British Journal of Haematology 117, 531 540.
    • (2002) British Journal of Haematology , vol.117 , pp. 531-540
    • Hoshino, K.1    Asou, N.2    Okubo, T.3    Suzushima, H.4    Kiyokawa, T.5    Kawano, F.6    Mitsuya, H.7
  • 32
    • 0030909701 scopus 로고    scopus 로고
    • DNA methylation changes in hematologic malignancies: Biologic and clinical implications
    • Issa J.P., Baylin S.B. Herman J.G. (1997) DNA methylation changes in hematologic malignancies: biologic and clinical implications. Leukemia 11 (Suppl. 7 11.
    • (1997) Leukemia , vol.11 , Issue.SUPPL. , pp. 7-11
    • Issa, J.P.1    Baylin, S.B.2    Herman, J.G.3
  • 35
    • 33745728247 scopus 로고    scopus 로고
    • Persistent infection of hepatitis B virus is involved in high rate of p16 methylation in hepatocellular carcinoma
    • Jicai Z., Zongtao Y., Jun L., Haiping L., Jianmin W. Lihua H. (2006) Persistent infection of hepatitis B virus is involved in high rate of p16 methylation in hepatocellular carcinoma. Molecular Carcinogenesis 45, 530 536.
    • (2006) Molecular Carcinogenesis , vol.45 , pp. 530-536
    • Jicai, Z.1    Zongtao, Y.2    Jun, L.3    Haiping, L.4    Jianmin, W.5    Lihua, H.6
  • 36
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones P.A. Baylin S.B. (2002) The fundamental role of epigenetic events in cancer. Nature Reviews. Genetics 3, 415 428.
    • (2002) Nature Reviews. Genetics , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 37
    • 0036121312 scopus 로고    scopus 로고
    • Epstein-Barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma
    • Kang G.H., Lee S., Kim W.H., Lee H.W., Kim J.C., Rhyu M.G. Ro J.Y. (2002) Epstein-Barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma. American Journal of Pathology 160, 787 794.
    • (2002) American Journal of Pathology , vol.160 , pp. 787-794
    • Kang, G.H.1    Lee, S.2    Kim, W.H.3    Lee, H.W.4    Kim, J.C.5    Rhyu, M.G.6    Ro, J.Y.7
  • 39
    • 24644488431 scopus 로고    scopus 로고
    • Epstein-Barr virus and p16INK4A methylation in squamous cell carcinoma and precancerous lesions of the cervix uteri
    • Kim N.R., Lin Z., Kim K.R., Cho H.Y. Kim I. (2005) Epstein-Barr virus and p16INK4A methylation in squamous cell carcinoma and precancerous lesions of the cervix uteri. Journal of Korean Medical Science 20, 636 642.
    • (2005) Journal of Korean Medical Science , vol.20 , pp. 636-642
    • Kim, N.R.1    Lin, Z.2    Kim, K.R.3    Cho, H.Y.4    Kim, I.5
  • 40
    • 0028358910 scopus 로고
    • Persistent erythema infectiosum-like rash as a prodrome of acute lymphoblastic leukaemia
    • Lee S.M., Kim D.G. Bang D. (1994) Persistent erythema infectiosum-like rash as a prodrome of acute lymphoblastic leukaemia. Pediatric Dermatology 11, 56 59.
    • (1994) Pediatric Dermatology , vol.11 , pp. 56-59
    • Lee, S.M.1    Kim, D.G.2    Bang, D.3
  • 41
    • 24344465856 scopus 로고    scopus 로고
    • Epigenetic changes in virus-associated human cancers
    • Li H.P., Leu Y.W. Chang Y.S. (2005) Epigenetic changes in virus-associated human cancers. Cell Research 15, 262 271.
    • (2005) Cell Research , vol.15 , pp. 262-271
    • Li, H.P.1    Leu, Y.W.2    Chang, Y.S.3
  • 42
  • 43
  • 44
    • 0032783679 scopus 로고    scopus 로고
    • Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy
    • Liaw Y.F., Chien R.N., Yeh C.T., Tsai S.L. Chu C.M. (1999) Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy. Hepatology 30, 567 572.
    • (1999) Hepatology , vol.30 , pp. 567-572
    • Liaw, Y.F.1    Chien, R.N.2    Yeh, C.T.3    Tsai, S.L.4    Chu, C.M.5
  • 45
    • 0033179375 scopus 로고    scopus 로고
    • Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia
    • Melki J.R., Vincent P.C. Clark S.J. (1999) Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia. Cancer Research 59, 3730 3740.
    • (1999) Cancer Research , vol.59 , pp. 3730-3740
    • Melki, J.R.1    Vincent, P.C.2    Clark, S.J.3
  • 46
    • 0035283201 scopus 로고    scopus 로고
    • Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia
    • Mizuno S., Chijiwa T., Okamura T., Akashi K., Fukumaki Y., Niho Y. Sasaki H. (2001) Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. Blood 97, 1172 1179.
    • (2001) Blood , vol.97 , pp. 1172-1179
    • Mizuno, S.1    Chijiwa, T.2    Okamura, T.3    Akashi, K.4    Fukumaki, Y.5    Niho, Y.6    Sasaki, H.7
  • 47
    • 5744243856 scopus 로고    scopus 로고
    • Pathobiology, classification, and diagnosis of myelodysplastic syndrom
    • In. ed. J.M. Rowe. vol. 7, no. 4 pp. Elsevier. Oxford, UK.
    • Mufti G.J. (2004) Pathobiology, classification, and diagnosis of myelodysplastic syndrom. In : Best Pactice & Research Clinical Haematology (ed. J.M. Rowe vol. 7, no. 4 pp. 543 557. Elsevier, Oxford, UK.
    • (2004) Best Pactice & Research Clinical Haematology , pp. 543-557
    • Mufti, G.J.1
  • 48
    • 0035958048 scopus 로고    scopus 로고
    • Foreign DNA integration. Genome-wide perturbations of methylation and transcription in the recipient genomes
    • Muller K., Heller H. Doerfler W. (2001) Foreign DNA integration. Genome-wide perturbations of methylation and transcription in the recipient genomes. Journal of Biological Chemistry 276, 14271 14278.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 14271-14278
    • Muller, K.1    Heller, H.2    Doerfler, W.3
  • 50
    • 0033792260 scopus 로고    scopus 로고
    • Infections and human cancer
    • Newton R. (2000) Infections and human cancer. Annals of Oncology 11, 1081 1082.
    • (2000) Annals of Oncology , vol.11 , pp. 1081-1082
    • Newton, R.1
  • 53
    • 0020049449 scopus 로고
    • Construction of human gene libraries from small amounts of peripheral blood: Analysis of beta-like globin genes
    • Poncz M., Solowiejczyk D., Harpel B., Mory Y., Schwartz E. Surrey S. (1982) Construction of human gene libraries from small amounts of peripheral blood: analysis of beta-like globin genes. Hemoglobin 6, 27 36.
    • (1982) Hemoglobin , vol.6 , pp. 27-36
    • Poncz, M.1    Solowiejczyk, D.2    Harpel, B.3    Mory, Y.4    Schwartz, E.5    Surrey, S.6
  • 54
    • 0033233233 scopus 로고    scopus 로고
    • P15INK4b gene methylation and myelodysplastic syndromes
    • Quesnel B. Fenaux P. (1999) P15INK4b gene methylation and myelodysplastic syndromes. Leukemia & Lymphoma 35, 437 443.
    • (1999) Leukemia & Lymphoma , vol.35 , pp. 437-443
    • Quesnel, B.1    Fenaux, P.2
  • 55
    • 0032523011 scopus 로고    scopus 로고
    • Methylation of the p15(INK4B) gene in myelodysplastic syndromes is frequent and acquired during disease progression
    • Quesnel B., Guillerm G., Vereecque R., Wattel E., Preudhomme C., Bauters F., Vanrumbeke M. Fenaux P. (1998) Methylation of the p15(INK4B) gene in myelodysplastic syndromes is frequent and acquired during disease progression. Blood 91, 2985 2990.
    • (1998) Blood , vol.91 , pp. 2985-2990
    • Quesnel, B.1    Guillerm, G.2    Vereecque, R.3    Wattel, E.4    Preudhomme, C.5    Bauters, F.6    Vanrumbeke, M.7    Fenaux, P.8
  • 56
    • 0345435970 scopus 로고    scopus 로고
    • Insertion of foreign DNA into an established mammalian genome can alter the methylation of cellular DNA sequences
    • Remus R., Kammer C., Heller H., Schmitz B., Schell G. Doerfler W. (1999) Insertion of foreign DNA into an established mammalian genome can alter the methylation of cellular DNA sequences. Journal of Virology 73, 1010 1022.
    • (1999) Journal of Virology , vol.73 , pp. 1010-1022
    • Remus, R.1    Kammer, C.2    Heller, H.3    Schmitz, B.4    Schell, G.5    Doerfler, W.6
  • 58
    • 0037220164 scopus 로고    scopus 로고
    • Parvovirus B19 infection and acute lymphoblastic leukaemia
    • Savasan S. Ozdemir O. (2003) Parvovirus B19 infection and acute lymphoblastic leukaemia. British Journal of Haematology 120, 168 169.
    • (2003) British Journal of Haematology , vol.120 , pp. 168-169
    • Savasan, S.1    Ozdemir, O.2
  • 59
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cyclin D/CDK4
    • Serrano M., Hannon G.J. Beach D. (1993) A new regulatory motif in cell-cyclin D/CDK4. Nature 336, 704 707.
    • (1993) Nature , vol.336 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 62
    • 33744484523 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV) and its associated human cancers - Genetics, epigenetics, pathobiology and novel therapeutics
    • Tao Q., Young L.S., Woodman C.B. Murray P.G. (2006) Epstein-Barr virus (EBV) and its associated human cancers - genetics, epigenetics, pathobiology and novel therapeutics. Frontiers in Bioscience 11, 2672 2713.
    • (2006) Frontiers in Bioscience , vol.11 , pp. 2672-2713
    • Tao, Q.1    Young, L.S.2    Woodman, C.B.3    Murray, P.G.4
  • 63
    • 0038189509 scopus 로고    scopus 로고
    • Hypermethylation of GpG islands in the promoter region of p15(INK4B) in acute promyelocytic leukemia represses p15(INK4B) expression and correlates with poor prognosis
    • Teofili L., Martini M., Luongo M., Diverio D., Capelli G., Breccia M., Lo Coco F., Leone G. Larocca L.M. (2003) Hypermethylation of GpG islands in the promoter region of p15(INK4B) in acute promyelocytic leukemia represses p15(INK4B) expression and correlates with poor prognosis. Leukemia 17, 919 924.
    • (2003) Leukemia , vol.17 , pp. 919-924
    • Teofili, L.1    Martini, M.2    Luongo, M.3    Diverio, D.4    Capelli, G.5    Breccia, M.6    Lo Coco, F.7    Leone, G.8    Larocca, L.M.9
  • 64
    • 0035134705 scopus 로고    scopus 로고
    • Methylation of the p15(INK4B) gene in myelodysplastic syndrome: It can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformation
    • Tien H.F., Tang J.H., Tsay W., Liu M.C., Lee F.Y., Wang C.H., Chen Y.C. Shen M.C. (2001) Methylation of the p15(INK4B) gene in myelodysplastic syndrome: it can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformation. British Journal of Haematology 112, 148 154.
    • (2001) British Journal of Haematology , vol.112 , pp. 148-154
    • Tien, H.F.1    Tang, J.H.2    Tsay, W.3    Liu, M.C.4    Lee, F.Y.5    Wang, C.H.6    Chen, Y.C.7    Shen, M.C.8
  • 66
    • 0037142622 scopus 로고    scopus 로고
    • Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells
    • Toyooka S., Carbone M., Toyooka K.O., Bocchetta M., Shivapurkar N., Minna J.D. Gazdar A.F. (2002) Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells. Oncogene 21, 4340 4344.
    • (2002) Oncogene , vol.21 , pp. 4340-4344
    • Toyooka, S.1    Carbone, M.2    Toyooka, K.O.3    Bocchetta, M.4    Shivapurkar, N.5    Minna, J.D.6    Gazdar, A.F.7
  • 69
    • 20044369539 scopus 로고    scopus 로고
    • Aberrant methylations in cancer cells: Where do they come from?
    • Ushijima T. Takada E.O. (2005) Aberrant methylations in cancer cells: where do they come from? Cancer Science 96, 206 211.
    • (2005) Cancer Science , vol.96 , pp. 206-211
    • Ushijima, T.1    Takada, E.O.2
  • 72
    • 0035666363 scopus 로고    scopus 로고
    • Meeting highlights: National Cancer Institute workshop on molecular signatures of infectious agents
    • Verma M., Lambert P.F. Srivastava S.K. (2001) Meeting highlights: National Cancer Institute workshop on molecular signatures of infectious agents. Disease Markers 17, 191 201.
    • (2001) Disease Markers , vol.17 , pp. 191-201
    • Verma, M.1    Lambert, P.F.2    Srivastava, S.K.3
  • 73
    • 0034654269 scopus 로고    scopus 로고
    • Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: Potential prognostic implications
    • Wong I.H., Ng M.H., Huang D.P. Lee J.C. (2000) Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: potential prognostic implications. Blood 95, 1942 1949.
    • (2000) Blood , vol.95 , pp. 1942-1949
    • Wong, I.H.1    Ng, M.H.2    Huang, D.P.3    Lee, J.C.4
  • 75
    • 0041924707 scopus 로고    scopus 로고
    • Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma
    • Yang B., Guo M., Herman J.G. Clark D.P. (2003) Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma. American Journal of Pathology 163, 1101 1107.
    • (2003) American Journal of Pathology , vol.163 , pp. 1101-1107
    • Yang, B.1    Guo, M.2    Herman, J.G.3    Clark, D.P.4
  • 76
    • 5344267510 scopus 로고    scopus 로고
    • Parvovirus B19 infection presenting as pre B-cell acute lymphoblastic leukaemia: A transient and progressive course in two children
    • Yetgin S., Cetin M., Aslan D., Ozyurek E., Anlar B. Uçkan D. (2004) Parvovirus B19 infection presenting as pre B-cell acute lymphoblastic leukaemia: a transient and progressive course in two children. Journal of Pediatric Hematology Oncology 26, 689 692.
    • (2004) Journal of Pediatric Hematology Oncology , vol.26 , pp. 689-692
    • Yetgin, S.1    Cetin, M.2    Aslan, D.3    Ozyurek, E.4    Anlar, B.5    Uçkan, D.6
  • 77
    • 33845689078 scopus 로고    scopus 로고
    • Parvovirus B19 infection in children with a variety of hematological disorders
    • Zaki Mel S., Hassan S.A., Seleim T. Lateef R.A. (2006) Parvovirus B19 infection in children with a variety of hematological disorders. Hematology 11, 261 266.
    • (2006) Hematology , vol.11 , pp. 261-266
    • Zaki Mel, S.1    Hassan, S.A.2    Seleim, T.3    Lateef, R.A.4
  • 78
    • 0036554834 scopus 로고    scopus 로고
    • Silencing of GSTP1 gene by CpG island DNA hypermethylation in HBV-associated hepatocellular carcinomas
    • Zhong S., Tang M.W., Yeo W., Liu C., Lo Y.M. Johnson P.J. (2002) Silencing of GSTP1 gene by CpG island DNA hypermethylation in HBV-associated hepatocellular carcinomas. Clinical Cancer Research 8, 1087 1092.
    • (2002) Clinical Cancer Research , vol.8 , pp. 1087-1092
    • Zhong, S.1    Tang, M.W.2    Yeo, W.3    Liu, C.4    Lo, Y.M.5    Johnson, P.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.