Role of epigenetic mechanisms in differential regulation of the dioxin-inducible human CYP1A1 and CYP1B1 genes

Molecular Pharmacology

Volumn 78, Issue 4, 2010, Pages 608-616

  Beedanagari, Sudheer R ^a   Taylor, Robert T ^c   Bui, Peter ^a   Wang, Feng ^a   Nickerson, Derek W ^b   Hankinson, Oliver ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DIOXIN; HISTONE ACETYLTRANSFERASE PCAF; HISTONE H3; HISTONE H4; PROTEIN P300; RNA POLYMERASE II; TATA BINDING PROTEIN; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYP1B1 PROTEIN, HUMAN; CYTOCHROME P450; UNSPECIFIC MONOOXYGENASE;

ACETYLATION; ARTICLE; CELL STRAIN HEPG2; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; BIOSYNTHESIS; COMPARATIVE STUDY; DRUG EFFECTS; ENZYME INDUCTION; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HEPG2 CELL LINE; PHYSIOLOGY; TUMOR CELL LINE;

ARYL HYDROCARBON HYDROXYLASES; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1B1; CYTOCHROME P-450 ENZYME SYSTEM; DIOXINS; ENZYME INDUCTION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEP G2 CELLS; HUMANS; TETRACHLORODIBENZODIOXIN;

EID: 77957242787     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.064899     Document Type: Article

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