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Volumn 1, Issue 4, 2011, Pages 1795-1835

Renal transport of organic anions and cations

Author keywords

[No Author keywords available]

Indexed keywords

ANION; CATION; ORGANIC ANION TRANSPORTER; ORGANIC CATION TRANSPORTER;

EID: 84862176841     PISSN: None     EISSN: 20404603     Source Type: Journal    
DOI: 10.1002/cphy.c100084     Document Type: Article
Times cited : (45)

References (478)
  • 3
    • 0016635787 scopus 로고
    • The kidney in regulation of plasma choline in the chicken
    • Acara M. The kidney in regulation of plasma choline in the chicken. Am J Physiol 228: 645-649, 1975.
    • (1975) Am J Physiol , vol.228 , pp. 645-649
    • Acara, M.1
  • 4
    • 0015811503 scopus 로고
    • Regulation of plasma choline by the renal tubule: Bidirectional transport of choline
    • Acara M, Rennick B. Regulation of plasma choline by the renal tubule: Bidirectional transport of choline. Am J Physiol 225: 1123-1128, 1973.
    • (1973) Am J Physiol , vol.225 , pp. 1123-1128
    • Acara, M.1    Rennick, B.2
  • 5
    • 18344417510 scopus 로고
    • Bidirectional renal tubular transport of free choline: A micropuncture study
    • Acara M, Roch-Ramel F, Rennick B. Bidirectional renal tubular transport of free choline: A micropuncture study. Am J Physiol 236: F112-F118, 1979.
    • (1979) Am J Physiol , vol.236
    • Acara, M.1    Roch-Ramel, F.2    Rennick, B.3
  • 7
    • 71449118407 scopus 로고    scopus 로고
    • Interaction of organic cations with organic anion transporters
    • Ahn SY, Eraly SA, Tsigelny I, Nigam SK. Interaction of organic cations with organic anion transporters. J Biol Chem284: 31422-31430, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 31422-31430
    • Ahn, S.Y.1    Eraly, S.A.2    Tsigelny, I.3    Nigam, S.K.4
  • 10
    • 23844469535 scopus 로고    scopus 로고
    • Integrated physiology of proximal tubular organic anion transport
    • Anzai N, Jutabha P, Kanai Y, Endou H. Integrated physiology of proximal tubular organic anion transport. Curr Opin Nephrol Hypertens 14: 472-479, 2005.
    • (2005) Curr Opin Nephrol Hypertens , vol.14 , pp. 472-479
    • Anzai, N.1    Jutabha, P.2    Kanai, Y.3    Endou, H.4
  • 11
    • 33846837206 scopus 로고    scopus 로고
    • New insights into renal transport of urate
    • Anzai N, Kanai Y, Endou H. New insights into renal transport of urate. Curr Opin Rheumatol 19: 151-157, 2007.
    • (2007) Curr Opin Rheumatol , vol.19 , pp. 151-157
    • Anzai, N.1    Kanai, Y.2    Endou, H.3
  • 12
    • 0035210249 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a murine hemicholinium-3-sensitive choline transporter
    • Apparsundaram S, Ferguson SM, Blakely RD. Molecular cloning and characterization of a murine hemicholinium-3-sensitive choline transporter. Biochem Soc Trans 29: 711-716, 2001.
    • (2001) Biochem Soc Trans , vol.29 , pp. 711-716
    • Apparsundaram, S.1    Ferguson, S.M.2    Blakely, R.D.3
  • 15
    • 33646405992 scopus 로고    scopus 로고
    • Androgen receptor is responsible for Rat organic cation transporter 2 gene regulation but not for rOCT1 and rOCT3
    • Asaka JI, Terada T, Okuda M, Katsura T, Inui KI. Androgen receptor is responsible for Rat organic cation transporter 2 gene regulation but not for rOCT1 and rOCT3. Pharm Res 23: 697-704, 2006.
    • (2006) Pharm Res , vol.23 , pp. 697-704
    • Asaka, J.I.1    Terada, T.2    Okuda, M.3    Katsura, T.4    Inui, K.I.5
  • 16
    • 0141813480 scopus 로고    scopus 로고
    • Stoichiometry of organic anion/dicarboxylate exchange in membrane vesicles from rat renal cortex and hOAT1-expressing cells
    • AslamkhanA, Han YH, Walden R, Sweet DH, Pritchard JB. Stoichiometry of organic anion/dicarboxylate exchange in membrane vesicles from rat renal cortex and hOAT1-expressing cells. Am J Physiol Renal Physiol 285: F775-F783, 2003.
    • (2003) Am J Physiol Renal Physiol , vol.285
    • Aslamkhan, A.1    Han, Y.H.2    Walden, R.3    Sweet, D.H.4    Pritchard, J.B.5
  • 18
    • 1942437498 scopus 로고    scopus 로고
    • Identification and characterization of human glucose transporter-like protein-9 (GLUT9): Alternative splicing alters trafficking
    • Augustin R, Carayannopoulos MO, Dowd LO, Phay JE, Moley JF, Moley KH. Identification and characterization of human glucose transporter-like protein-9 (GLUT9): Alternative splicing alters trafficking. J Biol Chem 279: 16229-16236, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 16229-16236
    • Augustin, R.1    Carayannopoulos, M.O.2    Dowd, L.O.3    Phay, J.E.4    Moley, J.F.5    Moley, K.H.6
  • 21
    • 1542298149 scopus 로고    scopus 로고
    • Mutation of amino acid 475 of rat organic cation transporter 2 (rOCT2) impairs organic cation transport
    • Bahn A, Hagos Y, Rudolph T, Burckhardt G. Mutation of amino acid 475 of rat organic cation transporter 2 (rOCT2) impairs organic cation transport. Biochimie 86: 133-136, 2004.
    • (2004) Biochimie , vol.86 , pp. 133-136
    • Bahn, A.1    Hagos, Y.2    Rudolph, T.3    Burckhardt, G.4
  • 22
    • 0038639696 scopus 로고    scopus 로고
    • RT-PCR-based evidence for the in vivo stimulation of renal tubular p-aminohippurate (PAH) transport by triiodothyronine (T3) or dexamethasone (DEXA) in kidney tissue of immature and adult rats
    • Bahn A, Hauss A, Appenroth D, Ebbinghaus D, Hagos Y, Steinmetzer P, Burckhardt G, Fleck C. RT-PCR-based evidence for the in vivo stimulation of renal tubular p-aminohippurate (PAH) transport by triiodothyronine (T3) or dexamethasone (DEXA) in kidney tissue of immature and adult rats. Exp Toxicol Pathol 54: 367-373, 2003.
    • (2003) Exp Toxicol Pathol , vol.54 , pp. 367-373
    • Bahn, A.1    Hauss, A.2    Appenroth, D.3    Ebbinghaus, D.4    Hagos, Y.5    Steinmetzer, P.6    Burckhardt, G.7    Fleck, C.8
  • 24
    • 0344845291 scopus 로고    scopus 로고
    • Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione
    • Bai J, Lai L, Yeo HC, Goh BC, Tan TM. Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione. Int J Biochem Cell Biol 36: 247-257, 2004.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 247-257
    • Bai, J.1    Lai, L.2    Yeo, H.C.3    Goh, B.C.4    Tan, T.M.5
  • 25
    • 0242290366 scopus 로고    scopus 로고
    • Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux
    • Bakhiya A, Bahn A, Burckhardt G, Wolff NA. Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux. Cell Physiol Biochem 13: 249-256, 2003.
    • (2003) Cell Physiol Biochem , vol.13 , pp. 249-256
    • Bakhiya, A.1    Bahn, A.2    Burckhardt, G.3    Wolff, N.A.4
  • 26
    • 45749127384 scopus 로고    scopus 로고
    • Identification of regions required for apical membrane localization of human multidrug resistance protein 2
    • Bandler PE, Westlake CJ, Grant CE, Cole SP, Deeley RG. Identification of regions required for apical membrane localization of human multidrug resistance protein 2. Mol Pharmacol 74: 9-19, 2008.
    • (2008) Mol Pharmacol , vol.74 , pp. 9-19
    • Bandler, P.E.1    Westlake, C.J.2    Grant, C.E.3    Cole, S.P.4    Deeley, R.G.5
  • 27
    • 0037151099 scopus 로고    scopus 로고
    • The human organic cation transporter (hOCT2) recognizes the degree of substrate ionization
    • Barendt WM, Wright SH. The human organic cation transporter (hOCT2) recognizes the degree of substrate ionization. J Biol Chem 277: 22491-22496, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 22491-22496
    • Barendt, W.M.1    Wright, S.H.2
  • 32
    • 0344838436 scopus 로고    scopus 로고
    • Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1
    • Bednarczyk D, Ekins S, Wikel JH, Wright SH. Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1. Mol Pharm 63: 489-498, 2003.
    • (2003) Mol Pharm , vol.63 , pp. 489-498
    • Bednarczyk, D.1    Ekins, S.2    Wikel, J.H.3    Wright, S.H.4
  • 33
    • 0020004347 scopus 로고
    • Electrical properties of the basolateral membrane of the straight portion of the rabbit proximal tubule
    • Bello-Reuss E. Electrical properties of the basolateral membrane of the straight portion of the rabbit proximal tubule. J Physiol 326: 49-63, 1982.
    • (1982) J Physiol , vol.326 , pp. 49-63
    • Bello-Reuss, E.1
  • 36
    • 0019615050 scopus 로고
    • Renal tubular transport and metabolism of organic cations by the rabbit
    • Besseghir K, Pearce LB, Rennick B. Renal tubular transport and metabolism of organic cations by the rabbit. Am J Physiol 241: F308-F314, 1981.
    • (1981) Am J Physiol , vol.241
    • Besseghir, K.1    Pearce, L.B.2    Rennick, B.3
  • 39
    • 0034995904 scopus 로고    scopus 로고
    • Multidrug transporters in prokaryotic and eukaryotic cells: Physiological functions and transport mechanisms
    • Blackmore CG, McNaughton PA, vanVeen HW. Multidrug transporters in prokaryotic and eukaryotic cells: Physiological functions and transport mechanisms. Mol Membr Biol 18: 97-103, 2001.
    • (2001) Mol Membr Biol , vol.18 , pp. 97-103
    • Blackmore, C.G.1    McNaughton, P.A.2    van Veen, H.W.3
  • 41
    • 22944433202 scopus 로고    scopus 로고
    • Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6)
    • Bleasby K, Hall LA, Perry JL, Mohrenweiser HW, Pritchard JB. Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6). J Pharmacol Exp Ther 314: 923-931, 2005.
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 923-931
    • Bleasby, K.1    Hall, L.A.2    Perry, J.L.3    Mohrenweiser, H.W.4    Pritchard, J.B.5
  • 42
    • 33846681607 scopus 로고    scopus 로고
    • Multidrug resistance-associated proteins 3, 4, and 5
    • Borst P, de WC, van de Wetering K. Multidrug resistance-associated proteins 3, 4, and 5. Pflugers Arch 453: 661-673, 2007.
    • (2007) Pflugers Arch , vol.453 , pp. 661-673
    • Borst, P.1    de, W.C.2    van de Wetering, K.3
  • 43
    • 18344413078 scopus 로고
    • Nicotinic acid transport by brush border membrane vesicles from rabbit kidney
    • Boumendil-Podevin EF, Podevin RA. Nicotinic acid transport by brush border membrane vesicles from rabbit kidney. Am J Physiol 240: F185-F191, 1981.
    • (1981) Am J Physiol , vol.240
    • Boumendil-Podevin, E.F.1    Podevin, R.A.2
  • 44
    • 0027372205 scopus 로고
    • Postnatal development of sex differences in renal tubular transport of p-aminohippurate (PAH) in rats
    • Bräunlich H, Meinig T, Grosch U. Postnatal development of sex differences in renal tubular transport of p-aminohippurate (PAH) in rats. Exp Toxicol Pathol 45: 309-313, 1993.
    • (1993) Exp Toxicol Pathol , vol.45 , pp. 309-313
    • Bräunlich, H.1    Meinig, T.2    Grosch, U.3
  • 45
    • 0026970160 scopus 로고
    • Stimulation of renal tubular transport of p-aminohippurate in rats of different ages by treatment with adrenocortical steroids
    • Bräunlich H, Rassbach H, Vogelsang S. Stimulation of renal tubular transport of p-aminohippurate in rats of different ages by treatment with adrenocortical steroids. Dev Pharmacol Ther 19: 1-5, 1992.
    • (1992) Dev Pharmacol Ther , vol.19 , pp. 1-5
    • Bräunlich, H.1    Rassbach, H.2    Vogelsang, S.3
  • 47
    • 0034703068 scopus 로고    scopus 로고
    • Mechanism of electrogenic cation transport by the cloned organic cation transporter 2 from rat
    • Budiman T, Bamberg E, Koepsell H, Nagel G. Mechanism of electrogenic cation transport by the cloned organic cation transporter 2 from rat. J Biol Chem 275: 29413-29420, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 29413-29420
    • Budiman, T.1    Bamberg, E.2    Koepsell, H.3    Nagel, G.4
  • 49
    • 2442700344 scopus 로고    scopus 로고
    • Rat and mouse differences in genderpredominant expression of organic anion transporter (Oat1-3; Slc22a6-8) mRNA levels
    • Buist SC, Klaassen CD. Rat and mouse differences in genderpredominant expression of organic anion transporter (Oat1-3; Slc22a6-8) mRNA levels. Drug Metab Dispos 32: 620-625, 2004.
    • (2004) Drug Metab Dispos , vol.32 , pp. 620-625
    • Buist, S.C.1    Klaassen, C.D.2
  • 51
    • 0033985338 scopus 로고    scopus 로고
    • Electrophysiologic characterization of an organic anion transporter cloned from winter flounder kidney (fROAT)
    • Burckhardt BC, Wolff NA, Burckhardt G. Electrophysiologic characterization of an organic anion transporter cloned from winter flounder kidney (fROAT). J Am Soc Nephrol 11: 9-17, 2000.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 9-17
    • Burckhardt, B.C.1    Wolff, N.A.2    Burckhardt, G.3
  • 52
    • 0033921479 scopus 로고    scopus 로고
    • Structure of renal organic anion and cation transporters
    • Burckhardt G, Wolff NA. Structure of renal organic anion and cation transporters. Am J Physiol Renal Physiol 278: F853-F866, 2000.
    • (2000) Am J Physiol Renal Physiol , vol.278
    • Burckhardt, G.1    Wolff, N.A.2
  • 55
    • 0021473920 scopus 로고
    • Luminal and peritubular ionic substitutions and intracellular potential of the rabbit proximal convoluted tubule
    • Cardinal J, Lapointe JY, Laprade R. Luminal and peritubular ionic substitutions and intracellular potential of the rabbit proximal convoluted tubule. Am J Physiol 247: F352-F364, 1984.
    • (1984) Am J Physiol , vol.247
    • Cardinal, J.1    Lapointe, J.Y.2    Laprade, R.3
  • 57
    • 0036302956 scopus 로고    scopus 로고
    • Sex differences in p-aminohippuric acid transport in rat kidney: Role of membrane fluidity and expression of OAT1
    • Cerrutti JA, Brandoni A, Quaglia NB, Torres AM. Sex differences in p-aminohippuric acid transport in rat kidney: Role of membrane fluidity and expression of OAT1. Mol Cell Biochem 233: 175-179, 2002.
    • (2002) Mol Cell Biochem , vol.233 , pp. 175-179
    • Cerrutti, J.A.1    Brandoni, A.2    Quaglia, N.B.3    Torres, A.M.4
  • 58
    • 0036446611 scopus 로고    scopus 로고
    • Effects of gender on the pharmacokinetics of drugs secreted by the renal organic anions transport systems in the rat
    • Cerrutti JA, Quaglia NB, Brandoni A, Torres AM. Effects of gender on the pharmacokinetics of drugs secreted by the renal organic anions transport systems in the rat. Pharmacol Res 45: 107-112, 2002.
    • (2002) Pharmacol Res , vol.45 , pp. 107-112
    • Cerrutti, J.A.1    Quaglia, N.B.2    Brandoni, A.3    Torres, A.M.4
  • 59
    • 0034760148 scopus 로고    scopus 로고
    • Characterization of the mechanisms involved in the gender differences in p-aminohippurate renal elimination in rats
    • Cerrutti JA, Quaglia NB, Torres AM. Characterization of the mechanisms involved in the gender differences in p-aminohippurate renal elimination in rats. Can J Physiol Pharmacol 79: 805-813, 2001.
    • (2001) Can J Physiol Pharmacol , vol.79 , pp. 805-813
    • Cerrutti, J.A.1    Quaglia, N.B.2    Torres, A.M.3
  • 61
    • 0035039326 scopus 로고    scopus 로고
    • Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney
    • Cha SH, Sekine T, Fukushima JI, Kanai Y, Kobayashi Y, Goya T, Endou H. Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Mol Pharmacol 59: 1277-1286, 2001.
    • (2001) Mol Pharmacol , vol.59 , pp. 1277-1286
    • Cha, S.H.1    Sekine, T.2    Fukushima, J.I.3    Kanai, Y.4    Kobayashi, Y.5    Goya, T.6    Endou, H.7
  • 62
    • 0000518648 scopus 로고    scopus 로고
    • Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta
    • Cha SH, Sekine T, Kusuhara H, Yu E, Kim JY, Kim DK, Sugiyama Y, Kanai Y, Endou H. Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. J Biol Chem 275: 4507-4512, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 4507-4512
    • Cha, S.H.1    Sekine, T.2    Kusuhara, H.3    Yu, E.4    Kim, J.Y.5    Kim, D.K.6    Sugiyama, Y.7    Kanai, Y.8    Endou, H.9
  • 63
    • 3542995726 scopus 로고    scopus 로고
    • The complexities of hepatic drug transport: Current knowledge and emerging concepts
    • Chandra P, Brouwer KL. The complexities of hepatic drug transport: Current knowledge and emerging concepts. Pharm Res 21: 719-735, 2004.
    • (2004) Pharm Res , vol.21 , pp. 719-735
    • Chandra, P.1    Brouwer, K.L.2
  • 64
    • 73949103220 scopus 로고    scopus 로고
    • Molecular mechanism of ATP-dependent solute transport by multidrug resistance-associated protein 1
    • Chang XB. Molecular mechanism of ATP-dependent solute transport by multidrug resistance-associated protein 1. Methods Mol Biol 596: 223-249, 2010.
    • (2010) Methods Mol Biol , vol.596 , pp. 223-249
    • Chang, X.B.1
  • 65
    • 0033028712 scopus 로고    scopus 로고
    • Effects of inhibitors and substitutes for chloride in lumen on p-aminohippurate transport by isolated perfused rabbit renal proximal tubules
    • Chatsudthipong V, Jutabha P, Evans KK, Dantzler WH. Effects of inhibitors and substitutes for chloride in lumen on p-aminohippurate transport by isolated perfused rabbit renal proximal tubules. J Pharmacol Exp Ther 288: 993-1001, 1999.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 993-1001
    • Chatsudthipong, V.1    Jutabha, P.2    Evans, K.K.3    Dantzler, W.H.4
  • 66
    • 1642422386 scopus 로고    scopus 로고
    • Rat multidrug resistance protein 4 (Mrp4, Abcc4): Molecular cloning, organ distribution, postnatal renal expression, and chemical inducibility
    • Chen C, Klaassen CD. Rat multidrug resistance protein 4 (Mrp4, Abcc4): Molecular cloning, organ distribution, postnatal renal expression, and chemical inducibility. Biochem Biophys Res Comm 317: 46-53, 2004.
    • (2004) Biochem Biophys Res Comm , vol.317 , pp. 46-53
    • Chen, C.1    Klaassen, C.D.2
  • 67
    • 0041589264 scopus 로고    scopus 로고
    • Utility of Mdr1-gene deficient mice in assessing the impact of P-glycoprotein on pharmacokinetics and pharmacodynamics in drug discovery and development
    • Chen C, Liu X, Smith BJ. Utility of Mdr1-gene deficient mice in assessing the impact of P-glycoprotein on pharmacokinetics and pharmacodynamics in drug discovery and development. Curr Drug Metab 4: 272-291, 2003.
    • (2003) Curr Drug Metab , vol.4 , pp. 272-291
    • Chen, C.1    Liu, X.2    Smith, B.J.3
  • 71
    • 0035823559 scopus 로고    scopus 로고
    • Transport of cyclic nucleotides and estradiol 17-β-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine
    • Chen ZS, Lee K, Kruh GD. Transport of cyclic nucleotides and estradiol 17-β-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine. J Biol Chem 276: 33747-33754, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 33747-33754
    • Chen, Z.S.1    Lee, K.2    Kruh, G.D.3
  • 72
    • 0036606023 scopus 로고    scopus 로고
    • Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system
    • Chen ZS, Lee K, Walther S, Raftogianis RB, Kuwano M, Zeng H, Kruh GD. Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system. Cancer Res 62: 3144-3150, 2002.
    • (2002) Cancer Res , vol.62 , pp. 3144-3150
    • Chen, Z.S.1    Lee, K.2    Walther, S.3    Raftogianis, R.B.4    Kuwano, M.5    Zeng, H.6    Kruh, G.D.7
  • 73
    • 33846568546 scopus 로고    scopus 로고
    • ABCB1 pharmacogenetics: Progress, pitfalls, and promise
    • Chinn LW, Kroetz DL. ABCB1 pharmacogenetics: Progress, pitfalls, and promise. Clin Pharmacol Ther 81: 265-269, 2007.
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 265-269
    • Chinn, L.W.1    Kroetz, D.L.2
  • 76
    • 13744263546 scopus 로고    scopus 로고
    • Regulation of organic cation transport
    • Ciarimboli G, Schlatter E. Regulation of organic cation transport. Pflugers Arch 449: 423-441, 2005.
    • (2005) Pflugers Arch , vol.449 , pp. 423-441
    • Ciarimboli, G.1    Schlatter, E.2
  • 78
    • 0032856603 scopus 로고    scopus 로고
    • The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1
    • Cihlar T, LinDC, Pritchard JB, Fuller MD, MendelDB, Sweet DH. The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1. Mol Pharmacol 56: 570-580, 1999.
    • (1999) Mol Pharmacol , vol.56 , pp. 570-580
    • Cihlar, T.1    Lin, D.C.2    Pritchard, J.B.3    Fuller, M.D.4    Mendel, D.B.5    Sweet, D.H.6
  • 79
    • 0028367599 scopus 로고
    • Physiologic and pathophysiologic roles of endothelin in the kidney
    • Clavell AL, Burnett JC Jr. Physiologic and pathophysiologic roles of endothelin in the kidney. Curr Opin Nephrol Hypertens 3: 66-72, 1994.
    • (1994) Curr Opin Nephrol Hypertens , vol.3 , pp. 66-72
    • Clavell, A.L.1    Burnett Jr., J.C.2
  • 80
    • 0013835942 scopus 로고
    • Renal tubular transport of water, solute, and PAH in rats loaded with isotonic saline
    • Cortney MA, Mylle M, Lassiter WE, Gottschalk CW. Renal tubular transport of water, solute, and PAH in rats loaded with isotonic saline. Am J Physiol 209: 1199-1205, 1965.
    • (1965) Am J Physiol , vol.209 , pp. 1199-1205
    • Cortney, M.A.1    Mylle, M.2    Lassiter, W.E.3    Gottschalk, C.W.4
  • 82
    • 0345299165 scopus 로고    scopus 로고
    • Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells
    • Cui Y, Konig J, Buchholz JK, Spring H, Leier I, Keppler D. Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells. Mol Pharmacol 55: 929-937, 1999.
    • (1999) Mol Pharmacol , vol.55 , pp. 929-937
    • Cui, Y.1    Konig, J.2    Buchholz, J.K.3    Spring, H.4    Leier, I.5    Keppler, D.6
  • 83
    • 0032997095 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir
    • Cundy KC. Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir. Clin Pharmacokinet 36: 127-143, 1999.
    • (1999) Clin Pharmacokinet , vol.36 , pp. 127-143
    • Cundy, K.C.1
  • 84
    • 33846230114 scopus 로고    scopus 로고
    • Genetic susceptibility to diclofenac-induced hepatotoxicity: Contribution of UGT2B7, CYP2C8, and ABCC2 genotypes
    • Daly AK, Aithal GP, Leathart JB, Swainsbury RA, Dang TS, Day CP. Genetic susceptibility to diclofenac-induced hepatotoxicity: Contribution of UGT2B7, CYP2C8, and ABCC2 genotypes. Gastroenterology 132: 272-281, 2007.
    • (2007) Gastroenterology , vol.132 , pp. 272-281
    • Daly, A.K.1    Aithal, G.P.2    Leathart, J.B.3    Swainsbury, R.A.4    Dang, T.S.5    Day, C.P.6
  • 85
    • 0029948636 scopus 로고    scopus 로고
    • Comparative aspects of renal urate transport
    • Dantzler WH. Comparative aspects of renal urate transport. Kidney Int 49: 1549-1551, 1996.
    • (1996) Kidney Int , vol.49 , pp. 1549-1551
    • Dantzler, W.H.1
  • 86
    • 0342872089 scopus 로고    scopus 로고
    • Renal tubular secretion of organic anions
    • Dantzler WH. Renal tubular secretion of organic anions. Adv Drug Del Rev 25: 217-230, 1997.
    • (1997) Adv Drug Del Rev , vol.25 , pp. 217-230
    • Dantzler, W.H.1
  • 87
    • 0019063952 scopus 로고
    • Comparative nephron function in reptiles, birds, and mammals
    • Dantzler WH, Braun EJ. Comparative nephron function in reptiles, birds, and mammals. Am J Physiol 239: R197-R213, 1980.
    • (1980) Am J Physiol , vol.239
    • Dantzler, W.H.1    Braun, E.J.2
  • 88
    • 0024578829 scopus 로고
    • Brush-border TEA transport in intact proximal tubules and isolated membrane vesicles
    • Dantzler WH, Brokl O, Wright SH. Brush-border TEA transport in intact proximal tubules and isolated membrane vesicles. Am J Physiol 256: F290-F297, 1989.
    • (1989) Am J Physiol , vol.256
    • Dantzler, W.H.1    Brokl, O.2    Wright, S.H.3
  • 89
    • 0031762088 scopus 로고    scopus 로고
    • Basolateral choline transport in isolated rabbit renal proximal tubule
    • Dantzler WH, Evans KK, Wright SH. Basolateral choline transport in isolated rabbit renal proximal tubule. Pflugers Arch 436: 899-905, 1998.
    • (1998) Pflugers Arch , vol.436 , pp. 899-905
    • Dantzler, W.H.1    Evans, K.K.2    Wright, S.H.3
  • 90
    • 0344655811 scopus 로고    scopus 로고
    • Renal tubular transport of organic anions and cations
    • Goldstein RS, editor. Renal Toxicology. New York: Pergamon
    • Dantzler WH, Wright SH. Renal tubular transport of organic anions and cations. In: Goldstein RS, editor. Comprehensive Toxicology. V. 7. Renal Toxicology. New York: Pergamon, 61-75, 1997.
    • (1997) Comprehensive Toxicology , vol.7 , pp. 61-75
    • Dantzler, W.H.1    Wright, S.H.2
  • 91
    • 0346654145 scopus 로고    scopus 로고
    • Themolecular and cellular physiology of basolateral organic anion transport in mammalian renal tubules
    • Dantzler WH, Wright SH. Themolecular and cellular physiology of basolateral organic anion transport in mammalian renal tubules. Biochim Biophys Acta 1618: 185-193, 2003.
    • (2003) Biochim Biophys Acta , vol.1618 , pp. 185-193
    • Dantzler, W.H.1    Wright, S.H.2
  • 92
    • 0025955212 scopus 로고
    • Basolateral tetraethylammonium transport in intact tubules: Specificity and transstimulation
    • Dantzler WH, Wright SH, Chatsudthipong V, Brokl O. Basolateral tetraethylammonium transport in intact tubules: Specificity and transstimulation. Am J Physiol 261: F386-F392, 1991.
    • (1991) Am J Physiol , vol.261
    • Dantzler, W.H.1    Wright, S.H.2    Chatsudthipong, V.3    Brokl, O.4
  • 93
    • 0029079760 scopus 로고
    • +/organic cations in the rat proximal tubule. Kinetics, dependence on pH; specificity as compared with the contraluminal organic cationtransport system
    • +/organic cations in the rat proximal tubule. Kinetics, dependence on pH; specificity as compared with the contraluminal organic cationtransport system. Pflugers Arch 430: 477-492, 1995.
    • (1995) Pflugers Arch , vol.430 , pp. 477-492
    • David, C.1    Rumrich, G.2    Ullrich, K.J.3
  • 94
    • 33745835398 scopus 로고    scopus 로고
    • Transmembrane transport of endoand xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins
    • Deeley RG, Westlake C, Cole SP. Transmembrane transport of endoand xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins. Physiol Rev 86: 849-899, 2006.
    • (2006) Physiol Rev , vol.86 , pp. 849-899
    • Deeley, R.G.1    Westlake, C.2    Cole, S.P.3
  • 95
    • 18044387775 scopus 로고    scopus 로고
    • Differential contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in vivo renal uptake of uremic toxins in rats
    • Deguchi T, Kouno Y, Terasaki T, Takadate A, Otagiri M. Differential contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in vivo renal uptake of uremic toxins in rats. Pharm Res 22: 619-627, 2005.
    • (2005) Pharm Res , vol.22 , pp. 619-627
    • Deguchi, T.1    Kouno, Y.2    Terasaki, T.3    Takadate, A.4    Otagiri, M.5
  • 96
    • 0347362498 scopus 로고    scopus 로고
    • Characterization of uremic toxin transport by organic anion transporters in the kidney
    • Deguchi T, Kusuhara H, Takadate A, Endou H, OtagiriM, Sugiyama Y. Characterization of uremic toxin transport by organic anion transporters in the kidney. Kidney Int 65: 162-174, 2004.
    • (2004) Kidney Int , vol.65 , pp. 162-174
    • Deguchi, T.1    Kusuhara, H.2    Takadate, A.3    Endou, H.4    Otagiri, M.5    Sugiyama, Y.6
  • 97
    • 0036233041 scopus 로고    scopus 로고
    • Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney
    • Deguchi T, Ohtsuki S, Otagiri M, Takanaga H, Asaba H, Mori S, Terasaki T. Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney. Kidney Int 61: 1760-1768, 2002.
    • (2002) Kidney Int , vol.61 , pp. 1760-1768
    • Deguchi, T.1    Ohtsuki, S.2    Otagiri, M.3    Takanaga, H.4    Asaba, H.5    Mori, S.6    Terasaki, T.7
  • 98
    • 22944463031 scopus 로고    scopus 로고
    • Renal clearance of endogenous hippurate correlates with expression levels of renal organic anion transporters in uremic rats
    • Deguchi T, Takemoto M, Uehara N, Lindup WE, Suenaga A, Otagiri M. Renal clearance of endogenous hippurate correlates with expression levels of renal organic anion transporters in uremic rats. J Pharmacol Exp Ther 314: 932-938, 2005.
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 932-938
    • Deguchi, T.1    Takemoto, M.2    Uehara, N.3    Lindup, W.E.4    Suenaga, A.5    Otagiri, M.6
  • 99
    • 0032933142 scopus 로고    scopus 로고
    • Dexamethasone modulation of multidrug transporters in normal tissues
    • Demeule M, Jodoin J, Beaulieu E, Brossard M, Beliveau R. Dexamethasone modulation of multidrug transporters in normal tissues. FEBS Lett 442: 208-214, 1999.
    • (1999) FEBS Lett , vol.442 , pp. 208-214
    • Demeule, M.1    Jodoin, J.2    Beaulieu, E.3    Brossard, M.4    Beliveau, R.5
  • 101
    • 0034010850 scopus 로고    scopus 로고
    • Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1)
    • Dresser MJ, Gray AT, Giacomini KM. Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1). J Pharmacol Exp Ther 292: 1146-1152, 2000.
    • (2000) J Pharmacol Exp Ther , vol.292 , pp. 1146-1152
    • Dresser, M.J.1    Gray, A.T.2    Giacomini, K.M.3
  • 102
    • 29044445315 scopus 로고    scopus 로고
    • Transepithelial urate transport by avian renal proximal tubule epithelium in primary culture
    • Dudas PL, Pelis RM, Braun EJ, Renfro JL. Transepithelial urate transport by avian renal proximal tubule epithelium in primary culture. J Exp Biol 208: 4305-4315, 2005.
    • (2005) J Exp Biol , vol.208 , pp. 4305-4315
    • Dudas, P.L.1    Pelis, R.M.2    Braun, E.J.3    Renfro, J.L.4
  • 104
    • 33845876683 scopus 로고    scopus 로고
    • Interaction of nonsteroidal anti-inflammatory drugs with multidrug resistance protein (MRP) 2/A
    • El Sheikh AA, Van Den Heuvel JJ, Koenderink JB, Russel FG. Interaction of nonsteroidal anti-inflammatory drugs with multidrug resistance protein (MRP) 2/A. J Pharmacol Exp Ther 320: 229-235, 2007.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 229-235
    • El Sheikh, A.A.1    Van Den Heuvel, J.J.2    Koenderink, J.B.3    Russel, F.G.4
  • 105
    • 52949106057 scopus 로고    scopus 로고
    • Functional role of arginine 375 in transmembrane helix 6 of multidrug resistance protein 4 (MRP4/ABCC4)
    • El-Sheikh AA, Van Den Heuvel JJ, Krieger E, Russel FG, Koenderink JB. Functional role of arginine 375 in transmembrane helix 6 of multidrug resistance protein 4 (MRP4/ABCC4). Mol Pharmacol 74: 964-971, 2008.
    • (2008) Mol Pharmacol , vol.74 , pp. 964-971
    • El-Sheikh, A.A.1    Van Den Heuvel, J.J.2    Krieger, E.3    Russel, F.G.4    Koenderink, J.B.5
  • 111
    • 0037427506 scopus 로고    scopus 로고
    • Organic anion and cation transporters occur in pairs of similar and similarly expressed genes
    • Eraly SA, Hamilton BA, Nigam SK. Organic anion and cation transporters occur in pairs of similar and similarly expressed genes. Biochem Biophys Res Commun 300: 333-342, 2003.
    • (2003) Biochem Biophys Res Commun , vol.300 , pp. 333-342
    • Eraly, S.A.1    Hamilton, B.A.2    Nigam, S.K.3
  • 112
    • 3042630508 scopus 로고    scopus 로고
    • Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters
    • Eraly SA, Monte JC, Nigam SK. Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters. Physiol Genomics 18: 12-24, 2004.
    • (2004) Physiol Genomics , vol.18 , pp. 12-24
    • Eraly, S.A.1    Monte, J.C.2    Nigam, S.K.3
  • 116
    • 0028855544 scopus 로고
    • Expression and function of P-glycoprotein in a mouse kidney cell line
    • Ernest S, Bello-Reuss E. Expression and function of P-glycoprotein in a mouse kidney cell line. Am J Physiol 269: C323-C333, 1995.
    • (1995) Am J Physiol , vol.269
    • Ernest, S.1    Bello-Reuss, E.2
  • 117
    • 0030663088 scopus 로고    scopus 로고
    • Expression of MDR1 (multidrug resistance) gene and its protein in normal human kidney
    • Ernest S, Rajaraman S, Megyesi J, Bello-Reuss EN. Expression of MDR1 (multidrug resistance) gene and its protein in normal human kidney. Nephron 77: 284-289, 1997.
    • (1997) Nephron , vol.77 , pp. 284-289
    • Ernest, S.1    Rajaraman, S.2    Megyesi, J.3    Bello-Reuss, E.N.4
  • 118
    • 0033936291 scopus 로고    scopus 로고
    • Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export
    • Evers R, de HM, Sparidans R, Beijnen J, Wielinga PR, Lankelma J, Borst P. Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export. Br J Cancer 83: 375-383, 2000.
    • (2000) Br J Cancer , vol.83 , pp. 375-383
    • Evers, R.1    de, H.M.2    Sparidans, R.3    Beijnen, J.4    Wielinga, P.R.5    Lankelma, J.6    Borst, P.7
  • 119
    • 0037163124 scopus 로고    scopus 로고
    • Role of the N-terminal transmembrane region of the multidrug resistance protein MRP2 in routing to the apical membrane in MDCKII cells
    • Fernandez SB, Hollo Z, Kern A, Bakos E, Fischer PA, Borst P, Evers R. Role of the N-terminal transmembrane region of the multidrug resistance protein MRP2 in routing to the apical membrane in MDCKII cells. J Biol Chem 277: 31048-31055, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 31048-31055
    • Fernandez, S.B.1    Hollo, Z.2    Kern, A.3    Bakos, E.4    Fischer, P.A.5    Borst, P.6    Evers, R.7
  • 121
    • 0035209568 scopus 로고    scopus 로고
    • The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism
    • Fisher MB, Paine MF, Strelevitz TJ, Wrighton SA. The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism. Drug Metab Rev 33: 273-297, 2001.
    • (2001) Drug Metab Rev , vol.33 , pp. 273-297
    • Fisher, M.B.1    Paine, M.F.2    Strelevitz, T.J.3    Wrighton, S.A.4
  • 124
    • 29244467701 scopus 로고    scopus 로고
    • +-independent choline transport in primary cultures of neurons from mouse cerebral cortex
    • +-independent choline transport in primary cultures of neurons from mouse cerebral cortex. Neurosci Lett 393: 216-221, 2006.
    • (2006) Neurosci Lett , vol.393 , pp. 216-221
    • Fujita, T.1    Shimada, A.2    Okada, N.3    Yamamoto, A.4
  • 125
    • 0032562616 scopus 로고    scopus 로고
    • Multidrug resistance protein. Identification of regions required for active transport of leukotriene C4
    • Gao M, Yamazaki M, Loe DW, Westlake CJ, Grant CE, Cole SP, Deeley RG. Multidrug resistance protein. Identification of regions required for active transport of leukotriene C4. J Biol Chem 273: 10733-10740, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 10733-10740
    • Gao, M.1    Yamazaki, M.2    Loe, D.W.3    Westlake, C.J.4    Grant, C.E.5    Cole, S.P.6    Deeley, R.G.7
  • 126
    • 0019306230 scopus 로고
    • Ketone body transport in renal brush border membrane vesicles
    • Garcia ML, Benavides J, Valdivieso F. Ketone body transport in renal brush border membrane vesicles. Biochim Biophys Acta 600: 922-930, 1980.
    • (1980) Biochim Biophys Acta , vol.600 , pp. 922-930
    • Garcia, M.L.1    Benavides, J.2    Valdivieso, F.3
  • 127
    • 0032879752 scopus 로고    scopus 로고
    • Inhibition of initial transport rate of basolateral organic anion carrier in renal PT by BK and phenylephrine
    • Gekle M, Mildenberger S, Sauvant C, Bednarczyk D, Wright SH, Dantzler WH. Inhibition of initial transport rate of basolateral organic anion carrier in renal PT by BK and phenylephrine. Am J Physiol 277: F251-F256, 1999.
    • (1999) Am J Physiol , vol.277
    • Gekle, M.1    Mildenberger, S.2    Sauvant, C.3    Bednarczyk, D.4    Wright, S.H.5    Dantzler, W.H.6
  • 130
    • 0036897215 scopus 로고    scopus 로고
    • The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules
    • Goralski KB, Lou G, Prowse MT, Gorboulev V, Volk C, Koepsell H, Sitar DS. The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules. J Pharmacol Exp Ther 303: 959-968, 2002.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 959-968
    • Goralski, K.B.1    Lou, G.2    Prowse, M.T.3    Gorboulev, V.4    Volk, C.5    Koepsell, H.6    Sitar, D.S.7
  • 131
    • 17844385032 scopus 로고    scopus 로고
    • Subtype-specific affinity for corticosterone of rat organic cation transporters rOCT1 and rOCT2 depends on three amino acids within the substrate binding region
    • Gorboulev V, Shatskaya N, Volk C, Koepsell H. Subtype-specific affinity for corticosterone of rat organic cation transporters rOCT1 and rOCT2 depends on three amino acids within the substrate binding region. Mol Pharmacol 67: 1612-1619, 2005.
    • (2005) Mol Pharmacol , vol.67 , pp. 1612-1619
    • Gorboulev, V.1    Shatskaya, N.2    Volk, C.3    Koepsell, H.4
  • 132
    • 0032723798 scopus 로고    scopus 로고
    • Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate
    • Gorboulev V, Volk C, Arndt P, Akhoundova A, Koepsell H. Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate. Mol Pharmacol 56: 1254-1261, 1999.
    • (1999) Mol Pharmacol , vol.56 , pp. 1254-1261
    • Gorboulev, V.1    Volk, C.2    Arndt, P.3    Akhoundova, A.4    Koepsell, H.5
  • 133
    • 37349126109 scopus 로고    scopus 로고
    • High-affinity cation binding to transporter OCT1 induces movement of helix 11 and blocks transport after mutations in a modelled interaction domain between two helices
    • Gorbunov D, Gorboulev V, Shatskaya N, Mueller T, Bamberg E, Friedrich T, Koepsell H. High-affinity cation binding to transporter OCT1 induces movement of helix 11 and blocks transport after mutations in a modelled interaction domain between two helices. Mol Pharmacol 73: 50-61, 2008.
    • (2008) Mol Pharmacol , vol.73 , pp. 50-61
    • Gorbunov, D.1    Gorboulev, V.2    Shatskaya, N.3    Mueller, T.4    Bamberg, E.5    Friedrich, T.6    Koepsell, H.7
  • 134
    • 59649127836 scopus 로고    scopus 로고
    • The carnitine transporter SLC22A5 is not a general drug transporter, but it efficiently translocates mildronate
    • Grigat S, Fork C, Bach M, Golz S, Geerts A, Schomig E, Grundemann D. The carnitine transporter SLC22A5 is not a general drug transporter, but it efficiently translocates mildronate. Drug Metab Dispos 37: 330-337, 2009.
    • (2009) Drug Metab Dispos , vol.37 , pp. 330-337
    • Grigat, S.1    Fork, C.2    Bach, M.3    Golz, S.4    Geerts, A.5    Schomig, E.6    Grundemann, D.7
  • 135
    • 0028213115 scopus 로고
    • Peritubular organic cation transport in isolated rabbit proximal tubules
    • Groves CE, Evans K, Dantzler WH, Wright SH. Peritubular organic cation transport in isolated rabbit proximal tubules. Am J Physiol 266: F450-F458, 1994.
    • (1994) Am J Physiol , vol.266
    • Groves, C.E.1    Evans, K.2    Dantzler, W.H.3    Wright, S.H.4
  • 136
    • 31144465910 scopus 로고    scopus 로고
    • Sex differences in the mRNA, protein, and functional expression of organic anion transporter (Oat) 1, Oat3, and organic cation transporter (Oct) 2 in rabbit renal proximal tubules
    • Groves CE, Suhre WB, Cherrington NJ, Wright SH. Sex differences in the mRNA, protein, and functional expression of organic anion transporter (Oat) 1, Oat3, and organic cation transporter (Oct) 2 in rabbit renal proximal tubules. J Pharmacol Exp Ther 316: 743-752, 2006.
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 743-752
    • Groves, C.E.1    Suhre, W.B.2    Cherrington, N.J.3    Wright, S.H.4
  • 137
    • 0028063302 scopus 로고
    • Drug excretion mediated by a newprototype of polyspecific transporter
    • Gründemann D, Gorboulev V, Gambaryan S, Veyhl M, Koepsell H. Drug excretion mediated by a newprototype of polyspecific transporter. Nature 372: 549-552, 1994.
    • (1994) Nature , vol.372 , pp. 549-552
    • Gründemann, D.1    Gorboulev, V.2    Gambaryan, S.3    Veyhl, M.4    Koepsell, H.5
  • 139
  • 140
    • 33846692496 scopus 로고    scopus 로고
    • Human renal organic anion transporter 4 operates as an asymmetric urate transporter
    • Hagos Y, Stein D, Ugele B, Burckhardt G, Bahn A. Human renal organic anion transporter 4 operates as an asymmetric urate transporter. J Am Soc Nephrol 18: 430-439, 2007.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 430-439
    • Hagos, Y.1    Stein, D.2    Ugele, B.3    Burckhardt, G.4    Bahn, A.5
  • 141
    • 33749327002 scopus 로고    scopus 로고
    • Wide variety of locations for rodent MATE1, a transporter protein that mediates the final excretion step for toxic organic cations
    • Haisa M, Matsumoto T, Komatsu T, Mariyama Y. Wide variety of locations for rodent MATE1, a transporter protein that mediates the final excretion step for toxic organic cations. Am J Physiol Cell Physiol 291: C678-C86, 2006.
    • (2006) Am J Physiol Cell Physiol , vol.291
    • Haisa, M.1    Matsumoto, T.2    Komatsu, T.3    Mariyama, Y.4
  • 142
    • 77953784269 scopus 로고    scopus 로고
    • Transporter studies with the 3-O-sulfate conjugate of 17α-ethinylestradiol: Assessment of human kidney drug transporters
    • Han YH, Busler D, Hong Y, Tian Y, Chen C, Rodrigues AD. Transporter studies with the 3-O-sulfate conjugate of 17α-ethinylestradiol: Assessment of human kidney drug transporters. Drug Metab Dispos 38: 1064-1071, 2010.
    • (2010) Drug Metab Dispos , vol.38 , pp. 1064-1071
    • Han, Y.H.1    Busler, D.2    Hong, Y.3    Tian, Y.4    Chen, C.5    Rodrigues, A.D.6
  • 143
    • 18844371777 scopus 로고    scopus 로고
    • Impact of endotoxininduced changes in P-glycoprotein expression on disposition of doxorubicin in mice
    • Hartmann G, Vassileva V, Piquette-Miller M. Impact of endotoxininduced changes in P-glycoprotein expression on disposition of doxorubicin in mice. Drug Metab Dispos 33: 820-828, 2005.
    • (2005) Drug Metab Dispos , vol.33 , pp. 820-828
    • Hartmann, G.1    Vassileva, V.2    Piquette-Miller, M.3
  • 144
    • 18244428822 scopus 로고
    • Tetraethylammonium transport by isolated perfused snake renal tubules
    • Hawk CT, Dantzler WH. Tetraethylammonium transport by isolated perfused snake renal tubules. Am J Physiol 246: F476-F487, 1984.
    • (1984) Am J Physiol , vol.246
    • Hawk, C.T.1    Dantzler, W.H.2
  • 145
    • 0342699762 scopus 로고    scopus 로고
    • Molecular cloning, functional characterization and genomic organization of four alternatively spliced isoforms of the human organic cation transporter 1 (hOCT1/SLC22A1)
    • Hayer M, Bonisch H, Bruss M. Molecular cloning, functional characterization and genomic organization of four alternatively spliced isoforms of the human organic cation transporter 1 (hOCT1/SLC22A1). Ann Hum Genet 63: 473-482, 1999.
    • (1999) Ann Hum Genet , vol.63 , pp. 473-482
    • Hayer, M.1    Bonisch, H.2    Bruss, M.3
  • 146
    • 77958596325 scopus 로고    scopus 로고
    • Structure of a cationbound multidrug and toxin compound extrusion (MATE) transporter
    • He X, Szewczyk P, KaryakinA, Evin M, Chang G. Structure of a cationbound multidrug and toxin compound extrusion (MATE) transporter. Nature 467: 991-994, 2010.
    • (2010) Nature , vol.467 , pp. 991-994
    • He, X.1    Szewczyk, P.2    Karyakin, A.3    Evin, M.4    Chang, G.5
  • 150
    • 16844380011 scopus 로고    scopus 로고
    • Estimation of the three-dimensional pharmacophore of ligands for rat multidrug-resistance-associated protein 2 using ligand-based drug design techniques
    • Hirono S, Nakagome I, Imai R, Maeda K, Kusuhara H, Sugiyama Y. Estimation of the three-dimensional pharmacophore of ligands for rat multidrug-resistance-associated protein 2 using ligand-based drug design techniques. Pharm Res 22: 260-269, 2005.
    • (2005) Pharm Res , vol.22 , pp. 260-269
    • Hirono, S.1    Nakagome, I.2    Imai, R.3    Maeda, K.4    Kusuhara, H.5    Sugiyama, Y.6
  • 151
    • 0034008388 scopus 로고    scopus 로고
    • Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1
    • Ho ES, Lin DC, Mendel DB, Cihlar T. Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1. J Am Soc Nephrol 11: 383-393, 2000.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 383-393
    • Ho, E.S.1    Lin, D.C.2    Mendel, D.B.3    Cihlar, T.4
  • 153
    • 0016589414 scopus 로고
    • 1-methylnicotinamide and p-aminohippuric acid to a particulate fraction from dog kidney
    • 1-methylnicotinamide and p-aminohippuric acid to a particulate fraction from dog kidney. J Pharmacol Exp Ther 195: 22-33, 1975.
    • (1975) J Pharmacol Exp Ther , vol.195 , pp. 22-33
    • Holohan, P.D.1    Pessah, N.I.2    Ross, C.R.3
  • 154
    • 0019256661 scopus 로고
    • Mechanisms of organic cation transport in kidney plasma membrane vesicles: 1. Countertransport studies
    • Holohan PD, Ross CR. Mechanisms of organic cation transport in kidney plasma membrane vesicles: 1. Countertransport studies. J Pharmacol Exp Ther 215: 191-197, 1980.
    • (1980) J Pharmacol Exp Ther , vol.215 , pp. 191-197
    • Holohan, P.D.1    Ross, C.R.2
  • 155
    • 0019485093 scopus 로고
    • Mechanisms of organic cation transport in kidney plasma membrane vesicles: 2. DpH studies
    • Holohan PD, Ross CR. Mechanisms of organic cation transport in kidney plasma membrane vesicles: 2. DpH studies. J Pharmacol Exp Ther 216: 294-298, 1981.
    • (1981) J Pharmacol Exp Ther , vol.216 , pp. 294-298
    • Holohan, P.D.1    Ross, C.R.2
  • 157
    • 33847123246 scopus 로고    scopus 로고
    • The putative transmembrane segment 7 of human organic anion transporter hOAT1 dictates transporter substrate binding and stability
    • Hong M, Zhou F, Lee K, You G. The putative transmembrane segment 7 of human organic anion transporter hOAT1 dictates transporter substrate binding and stability. J Pharmacol Exp Ther 320: 1209-1215, 2007.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 1209-1215
    • Hong, M.1    Zhou, F.2    Lee, K.3    You, G.4
  • 158
    • 3843123206 scopus 로고    scopus 로고
    • Critical amino acid residues in transmembrane domain 1 of the human organic anion transporter hOAT1
    • Hong M, Zhou F, You G. Critical amino acid residues in transmembrane domain 1 of the human organic anion transporter hOAT1. J Biol Chem 279: 31478-31482, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 31478-31482
    • Hong, M.1    Zhou, F.2    You, G.3
  • 160
    • 0032919287 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney
    • Hosoyamada M, Sekine T, Kanai Y, Endou H. Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney. Am J Physiol 276: F122-F128, 1999.
    • (1999) Am J Physiol , vol.276
    • Hosoyamada, M.1    Sekine, T.2    Kanai, Y.3    Endou, H.4
  • 161
    • 0041489951 scopus 로고    scopus 로고
    • Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli
    • Huang Y, Lemieux MJ, Song J, Auer M, Wang DN. Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli. Science 301: 616-620, 2003.
    • (2003) Science , vol.301 , pp. 616-620
    • Huang, Y.1    Lemieux, M.J.2    Song, J.3    Auer, M.4    Wang, D.N.5
  • 163
    • 0346734163 scopus 로고    scopus 로고
    • Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion
    • Ichida K, Hosoyamada M, Hisatome I, Enomoto A, Hikita M, Endou H, Hosoya T. Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion. J Am Soc Nephrol 15: 164-173, 2004.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 164-173
    • Ichida, K.1    Hosoyamada, M.2    Hisatome, I.3    Enomoto, A.4    Hikita, M.5    Endou, H.6    Hosoya, T.7
  • 165
    • 67650753944 scopus 로고    scopus 로고
    • Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: Implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs
    • Ieiri I, Higuchi S, Sugiyama Y. Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: Implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs. Expert Opin Drug Metab Toxicol 5: 703-729, 2009.
    • (2009) Expert Opin Drug Metab Toxicol , vol.5 , pp. 703-729
    • Ieiri, I.1    Higuchi, S.2    Sugiyama, Y.3
  • 167
    • 33846420624 scopus 로고    scopus 로고
    • Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir
    • Imaoka T, Kusuhara H, Adachi M, Schuetz JD, Takeuchi K, Sugiyama Y. Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir. Mol Pharmacol 71: 619-627, 2007.
    • (2007) Mol Pharmacol , vol.71 , pp. 619-627
    • Imaoka, T.1    Kusuhara, H.2    Adachi, M.3    Schuetz, J.D.4    Takeuchi, K.5    Sugiyama, Y.6
  • 168
    • 24144434422 scopus 로고    scopus 로고
    • Molecular and functional characterization of an Na+-independent choline transporter in rat astrocytes
    • Inazu M, Takeda H, Matsumiya T. Molecular and functional characterization of an Na+-independent choline transporter in rat astrocytes. J Neurochem 94: 1427-1437, 2005.
    • (2005) J Neurochem , vol.94 , pp. 1427-1437
    • Inazu, M.1    Takeda, H.2    Matsumiya, T.3
  • 169
    • 0035851106 scopus 로고    scopus 로고
    • Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity
    • Ito K, Oleschuk CJ, Westlake C, Vasa MZ, Deeley RG, Cole SP. Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity. J Biol Chem 276: 38108-38114, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 38108-38114
    • Ito, K.1    Oleschuk, C.J.2    Westlake, C.3    Vasa, M.Z.4    Deeley, R.G.5    Cole, S.P.6
  • 170
    • 0035028211 scopus 로고    scopus 로고
    • Charged amino acids in the transmembrane domains are involved in the determination of the substrate specificity of rat Mrp2
    • Ito K, Suzuki H, Sugiyama Y. Charged amino acids in the transmembrane domains are involved in the determination of the substrate specificity of rat Mrp2. Mol Pharmacol 59: 1077-1085, 2001.
    • (2001) Mol Pharmacol , vol.59 , pp. 1077-1085
    • Ito, K.1    Suzuki, H.2    Sugiyama, Y.3
  • 172
    • 28144462450 scopus 로고    scopus 로고
    • Involvement of uric acid transporter in increased renal clearance of the xanthine oxidase inhibitor oxypurinol induced by a uricosuric agent, benzbromarone
    • Iwanaga T, Kobayashi D, Hirayama M, Maeda T, Tamai I. Involvement of uric acid transporter in increased renal clearance of the xanthine oxidase inhibitor oxypurinol induced by a uricosuric agent, benzbromarone. Drug Metab Dispos 33: 1791-1795, 2005.
    • (2005) Drug Metab Dispos , vol.33 , pp. 1791-1795
    • Iwanaga, T.1    Kobayashi, D.2    Hirayama, M.3    Maeda, T.4    Tamai, I.5
  • 174
    • 33846418041 scopus 로고    scopus 로고
    • Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition
    • Jedlitschky G, Hoffmann U, Kroemer HK. Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition. Expert Opin Drug Metab Toxicol 2: 351-366, 2006.
    • (2006) Expert Opin Drug Metab Toxicol , vol.2 , pp. 351-366
    • Jedlitschky, G.1    Hoffmann, U.2    Kroemer, H.K.3
  • 176
    • 0027497866 scopus 로고
    • Adverse drug interactions with nonsteroidal anti-inflammatory drugs (NSAIDs). Recognition, management and avoidance
    • Johnson AG, Seideman P, Day RO. Adverse drug interactions with nonsteroidal anti-inflammatory drugs (NSAIDs). Recognition, management and avoidance. Drug Saf 8: 99-127, 1993.
    • (1993) Drug Saf , vol.8 , pp. 99-127
    • Johnson, A.G.1    Seideman, P.2    Day, R.O.3
  • 177
    • 0034935038 scopus 로고    scopus 로고
    • Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene
    • Jonker JW, Wagenaar E, Mol CA, Buitelaar M, Koepsell H, Smit JW, Schinkel AH. Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene. Mol Cell Biol 21: 5471-5477, 2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 5471-5477
    • Jonker, J.W.1    Wagenaar, E.2    Mol, C.A.3    Buitelaar, M.4    Koepsell, H.5    Smit, J.W.6    Schinkel, A.H.7
  • 178
    • 0142123151 scopus 로고    scopus 로고
    • Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations
    • Jonker JW, Wagenaar E, Van Eijl S, Schinkel AH. Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations. Mol Cell Biol 23: 7902-7908, 2003.
    • (2003) Mol Cell Biol , vol.23 , pp. 7902-7908
    • Jonker, J.W.1    Wagenaar, E.2    Van Eijl, S.3    Schinkel, A.H.4
  • 183
    • 6344251595 scopus 로고    scopus 로고
    • Screening of the interaction between xenobiotic transporters and PDZ proteins
    • Kato Y, Yoshida K, Watanabe C, Sai Y, Tsuji A. Screening of the interaction between xenobiotic transporters and PDZ proteins. Pharm Res 21: 1886-1894, 2004.
    • (2004) Pharm Res , vol.21 , pp. 1886-1894
    • Kato, Y.1    Yoshida, K.2    Watanabe, C.3    Sai, Y.4    Tsuji, A.5
  • 184
    • 0032540101 scopus 로고    scopus 로고
    • Sequence analysis and functional characterization of the 5'-flanking region of the rat multidrug resistance protein 2 (mrp2) gene
    • Kauffmann HM, Schrenk D. Sequence analysis and functional characterization of the 5'-flanking region of the rat multidrug resistance protein 2 (mrp2) gene. Biochem Biophys Res Commun 245: 325-331, 1998.
    • (1998) Biochem Biophys Res Commun , vol.245 , pp. 325-331
    • Kauffmann, H.M.1    Schrenk, D.2
  • 185
    • 0033652766 scopus 로고    scopus 로고
    • Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome
    • Keitel V, Kartenbeck J, Nies AT, Spring H, Brom M, Keppler D. Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome. Hepatology 32: 1317-1328, 2000.
    • (2000) Hepatology , vol.32 , pp. 1317-1328
    • Keitel, V.1    Kartenbeck, J.2    Nies, A.T.3    Spring, H.4    Brom, M.5    Keppler, D.6
  • 186
    • 0032569029 scopus 로고    scopus 로고
    • Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta
    • Kekuda R, Prasad PD, Wu X, Wang H, Fei YJ, Leibach FH, Ganapathy V. Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta. J Biol Chem 273: 15971-15979, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 15971-15979
    • Kekuda, R.1    Prasad, P.D.2    Wu, X.3    Wang, H.4    Fei, Y.J.5    Leibach, F.H.6    Ganapathy, V.7
  • 189
    • 33747606242 scopus 로고    scopus 로고
    • Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation
    • Kikuchi R, Kusuhara H, Hattori N, Shiota K, Kim I, Gonzalez FJ, Sugiyama Y. Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation. Mol Pharmacol 70: 887-896, 2006.
    • (2006) Mol Pharmacol , vol.70 , pp. 887-896
    • Kikuchi, R.1    Kusuhara, H.2    Hattori, N.3    Shiota, K.4    Kim, I.5    Gonzalez, F.J.6    Sugiyama, Y.7
  • 191
    • 0030989594 scopus 로고    scopus 로고
    • Effects of pH on basolateral tetraethylammonium transport in snake renal proximal tubules
    • Kim YK, Dantzler WH. Effects of pH on basolateral tetraethylammonium transport in snake renal proximal tubules. Am J Physiol 272: R955-R961, 1997.
    • (1997) Am J Physiol , vol.272
    • Kim, Y.K.1    Dantzler, W.H.2
  • 192
    • 0018747991 scopus 로고
    • Transport of organic ions in renal cortical luminal and antiluminal membrane vesicles
    • Kinsella JL, Holohan PD, Pessah NI, Ross CR. Transport of organic ions in renal cortical luminal and antiluminal membrane vesicles. J Pharmacol Exp Ther 209: 443-450, 1979.
    • (1979) J Pharmacol Exp Ther , vol.209 , pp. 443-450
    • Kinsella, J.L.1    Holohan, P.D.2    Pessah, N.I.3    Ross, C.R.4
  • 193
    • 77949398878 scopus 로고    scopus 로고
    • Xenobiotic, bile acid, and cholesterol transporters: Function and regulation
    • Klaassen CD, Aleksunes LM. Xenobiotic, bile acid, and cholesterol transporters: Function and regulation. Pharmacol Rev 62: 1-96, 2010.
    • (2010) Pharmacol Rev , vol.62 , pp. 1-96
    • Klaassen, C.D.1    Aleksunes, L.M.2
  • 195
    • 17644380567 scopus 로고    scopus 로고
    • Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7])
    • Kobayashi Y, Ohshiro N, Sakai R, Ohbayashi M, Kohyama N, Yamamoto T. Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]). J Pharm Pharmacol 57: 573-578, 2005.
    • (2005) J Pharm Pharmacol , vol.57 , pp. 573-578
    • Kobayashi, Y.1    Ohshiro, N.2    Sakai, R.3    Ohbayashi, M.4    Kohyama, N.5    Yamamoto, T.6
  • 196
    • 78651362677 scopus 로고    scopus 로고
    • Substrate recognition and translocation by polyspecific organic cation transporters
    • Koepsell H. Substrate recognition and translocation by polyspecific organic cation transporters. Biol Chem 392: 95-101, 2011.
    • (2011) Biol Chem , vol.392 , pp. 95-101
    • Koepsell, H.1
  • 197
    • 1242295185 scopus 로고    scopus 로고
    • The SLC22 drug transporter family
    • Koepsell H, Endou H. The SLC22 drug transporter family. Pflugers Arch 447: 666-676, 2004.
    • (2004) Pflugers Arch , vol.447 , pp. 666-676
    • Koepsell, H.1    Endou, H.2
  • 198
    • 0036206004 scopus 로고    scopus 로고
    • Immunolocalization of multispecific organic anion transporters, OAT1, OAT2, and OAT3, in rat kidney
    • Kojima R, Sekine T, Kawachi M, Cha SH, Suzuki Y, Endou H. Immunolocalization of multispecific organic anion transporters, OAT1, OAT2, and OAT3, in rat kidney. J Am Soc Nephrol 13: 848-857, 2002.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 848-857
    • Kojima, R.1    Sekine, T.2    Kawachi, M.3    Cha, S.H.4    Suzuki, Y.5    Endou, H.6
  • 199
    • 0344927562 scopus 로고    scopus 로고
    • Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
    • Konig J, Nies AT, Cui Y, Leier I, Keppler D. Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance. Biochim Biophys Acta 1461: 377-394, 1999.
    • (1999) Biochim Biophys Acta , vol.1461 , pp. 377-394
    • Konig, J.1    Nies, A.T.2    Cui, Y.3    Leier, I.4    Keppler, D.5
  • 200
    • 0037101913 scopus 로고    scopus 로고
    • Organic cation transporter mRNA and function in the rat superior cervical ganglion
    • Kristufek D, Rudorfer W, Pifl C, Huck S. Organic cation transporter mRNA and function in the rat superior cervical ganglion. J Physiol 543: 117-134, 2002.
    • (2002) J Physiol , vol.543 , pp. 117-134
    • Kristufek, D.1    Rudorfer, W.2    Pifl, C.3    Huck, S.4
  • 202
    • 0034842137 scopus 로고    scopus 로고
    • Carnitine transport by organic cation transporters and systemic carnitine deficiency
    • Lahjouji K, Mitchell GA, Qureshi IA. Carnitine transport by organic cation transporters and systemic carnitine deficiency. Mol Genet Metab 73: 287-297, 2001.
    • (2001) Mol Genet Metab , vol.73 , pp. 287-297
    • Lahjouji, K.1    Mitchell, G.A.2    Qureshi, I.A.3
  • 207
    • 15744367808 scopus 로고    scopus 로고
    • Polymorphisms in human organic aniontransporting polypeptide 1A2 (OATP1A2): Implications for altered drug disposition and central nervous system drug entry
    • Lee W, Glaeser H, Smith LH, Roberts RL, Moeckel GW, Gervasini G, Leake BF, Kim RB. Polymorphisms in human organic aniontransporting polypeptide 1A2 (OATP1A2): Implications for altered drug disposition and central nervous system drug entry. J Biol Chem 280: 9610-9617, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 9610-9617
    • Lee, W.1    Glaeser, H.2    Smith, L.H.3    Roberts, R.L.4    Moeckel, G.W.5    Gervasini, G.6    Leake, B.F.7    Kim, R.B.8
  • 208
    • 0034083906 scopus 로고    scopus 로고
    • ATP-dependent paraaminohippurate transport by apical multidrug resistance protein MRP2
    • Leier I, Hummel-Eisenbeiss J, Cui Y, Keppler D. ATP-dependent paraaminohippurate transport by apical multidrug resistance protein MRP2. Kidney Int 57: 1636-1642, 2000.
    • (2000) Kidney Int , vol.57 , pp. 1636-1642
    • Leier, I.1    Hummel-Eisenbeiss, J.2    Cui, Y.3    Keppler, D.4
  • 209
    • 0035958862 scopus 로고    scopus 로고
    • Transport of the b-O-Glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1)
    • Leslie E, Ito K, Upadhyaya P, Hecht S, Deeley R, Cole S. Transport of the β-O-Glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). J Biol Chem 276: 27846-27854, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 27846-27854
    • Leslie, E.1    Ito, K.2    Upadhyaya, P.3    Hecht, S.4    Deeley, R.5    Cole, S.6
  • 210
    • 0036229943 scopus 로고    scopus 로고
    • Tissue expression, ontogeny, and inducibility of rat organic anion transporting polypeptide 4
    • Li N, Hartley DP, Cherrington NJ, Klaassen CD. Tissue expression, ontogeny, and inducibility of rat organic anion transporting polypeptide 4. J Pharmacol Exp Ther 301: 551-560, 2002.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 551-560
    • Li, N.1    Hartley, D.P.2    Cherrington, N.J.3    Klaassen, C.D.4
  • 211
    • 45249105082 scopus 로고    scopus 로고
    • Tissue distribution, ontogeny and induction of the transporters Multidrug and toxin extrusion (MATE) 1 and MATE2 mRNA expression levels in mice
    • Lickteig AJ, Cheng X, Augustine LM, Klaassen CD, Cherrington NJ. Tissue distribution, ontogeny and induction of the transporters Multidrug and toxin extrusion (MATE) 1 and MATE2 mRNA expression levels in mice. Life Sci 83: 59-64, 2008.
    • (2008) Life Sci , vol.83 , pp. 59-64
    • Lickteig, A.J.1    Cheng, X.2    Augustine, L.M.3    Klaassen, C.D.4    Cherrington, N.J.5
  • 214
    • 0030940999 scopus 로고    scopus 로고
    • Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney
    • Lopez-Nieto CE, You G, Bush KT, Barros EJ, Beier DR, Nigam SK. Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney. J Biol Chem 272: 6471-6478, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 6471-6478
    • Lopez-Nieto, C.E.1    You, G.2    Bush, K.T.3    Barros, E.J.4    Beier, D.R.5    Nigam, S.K.6
  • 215
    • 0032573562 scopus 로고    scopus 로고
    • A missense mutation of mouse OCTN2, a sodium-dependent carnitine cotransporter, in the juvenile visceral steatosis mouse
    • Lu K, Nishimori H, Nakamura Y, Shima K, Kuwajima M. A missense mutation of mouse OCTN2, a sodium-dependent carnitine cotransporter, in the juvenile visceral steatosis mouse. Biochem Biophys Res Commun 252: 590-594, 1998.
    • (1998) Biochem Biophys Res Commun , vol.252 , pp. 590-594
    • Lu, K.1    Nishimori, H.2    Nakamura, Y.3    Shima, K.4    Kuwajima, M.5
  • 216
    • 0032995116 scopus 로고    scopus 로고
    • Cloning of the human kidney PAH transporter: Narrow substrate specificity and regulation by protein kinase C
    • Lu R, Chan BS, Schuster VL. Cloning of the human kidney PAH transporter: Narrow substrate specificity and regulation by protein kinase C. Am J Physiol 276: F295-F303, 1999.
    • (1999) Am J Physiol , vol.276
    • Lu, R.1    Chan, B.S.2    Schuster, V.L.3
  • 218
    • 0016266214 scopus 로고
    • Active transport by insect malpighian tubules of acidic dyes and of acylamides
    • Maddrell SH, Gardiner BO, Pilcher DE, Reynolds SE. Active transport by insect malpighian tubules of acidic dyes and of acylamides. J Exp Biol 61: 357-377, 1974.
    • (1974) J Exp Biol , vol.61 , pp. 357-377
    • Maddrell, S.H.1    Gardiner, B.O.2    Pilcher, D.E.3    Reynolds, S.E.4
  • 219
    • 53049092262 scopus 로고    scopus 로고
    • Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells
    • Maeda A, Tsuruoka S, Kanai Y, Endou H, Saito K, Miyamoto E, Fujimura A. Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells. Eur J Pharmacol 596: 166-172, 2008.
    • (2008) Eur J Pharmacol , vol.596 , pp. 166-172
    • Maeda, A.1    Tsuruoka, S.2    Kanai, Y.3    Endou, H.4    Saito, K.5    Miyamoto, E.6    Fujimura, A.7
  • 221
    • 33745952758 scopus 로고    scopus 로고
    • Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1alpha
    • Maher JM, Slitt AL, Callaghan TN, Cheng X, Cheung C, Gonzalez FJ, Klaassen CD. Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1alpha. Biochem Pharmacol 72: 512-522, 2006.
    • (2006) Biochem Pharmacol , vol.72 , pp. 512-522
    • Maher, J.M.1    Slitt, A.L.2    Callaghan, T.N.3    Cheng, X.4    Cheung, C.5    Gonzalez, F.J.6    Klaassen, C.D.7
  • 222
    • 22344432207 scopus 로고    scopus 로고
    • Tissue distribution and hepatic and renal ontogeny of the multidrug resistanceassociated protein (Mrp) family in mice
    • Maher JM, Slitt AL, Cherrington NJ, Cheng X, Klaassen CD. Tissue distribution and hepatic and renal ontogeny of the multidrug resistanceassociated protein (Mrp) family in mice. Drug Metab Dispos 33: 947-955, 2005.
    • (2005) Drug Metab Dispos , vol.33 , pp. 947-955
    • Maher, J.M.1    Slitt, A.L.2    Cherrington, N.J.3    Cheng, X.4    Klaassen, C.D.5
  • 223
    • 0040935896 scopus 로고
    • Localization of nephron transport by stop flow analysis
    • Malvin RL, Wilde WS, Sullivan LP. Localization of nephron transport by stop flow analysis. Am J Physiol 194: 135-142, 1958.
    • (1958) Am J Physiol , vol.194 , pp. 135-142
    • Malvin, R.L.1    Wilde, W.S.2    Sullivan, L.P.3
  • 224
    • 0022118530 scopus 로고
    • Sodium-pyrazinoate cotransport in rabbit renal brush border membrane vesicles
    • Manganel M, Roch-Ramel F, MurerH. Sodium-pyrazinoate cotransport in rabbit renal brush border membrane vesicles. Am J Physiol 249: F400-F408, 1985.
    • (1985) Am J Physiol , vol.249
    • Manganel, M.1    Roch-Ramel, F.2    Murer, H.3
  • 225
    • 0000745868 scopus 로고
    • The structure and function of the kidney of Lophius piscatorius
    • Marshall E, Grafflin AL. The structure and function of the kidney of Lophius piscatorius. Bull Johns Hopkins Hosp 43: 205-235, 1928.
    • (1928) Bull Johns Hopkins Hosp , vol.43 , pp. 205-235
    • Marshall, E.1    Grafflin, A.L.2
  • 226
    • 0032949987 scopus 로고    scopus 로고
    • Active lucifer yellow secretion in renal proximal tubule: Evidence for organic anion transport system crossover
    • Masereeuw R, Moons MM, Toomey BH, Russel FG, Miller DS. Active lucifer yellow secretion in renal proximal tubule: Evidence for organic anion transport system crossover. J Pharmacol Exp Ther 289: 1104-1111, 1999.
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 1104-1111
    • Masereeuw, R.1    Moons, M.M.2    Toomey, B.H.3    Russel, F.G.4    Miller, D.S.5
  • 228
    • 77951091171 scopus 로고    scopus 로고
    • Therapeutic implications of renal anionic drug transporters
    • Masereeuw R, Russel FG. Therapeutic implications of renal anionic drug transporters. Pharmacol Ther 126: 200-216, 2010.
    • (2010) Pharmacol Ther , vol.126 , pp. 200-216
    • Masereeuw, R.1    Russel, F.G.2
  • 229
    • 0033988860 scopus 로고    scopus 로고
    • Endothelin B receptor-mediated regulation of ATP-driven drug secretion in renal proximal tubule
    • Masereeuw R, Terlouw SA, van Aubel RA, Russel FG, Miller DS. Endothelin B receptor-mediated regulation of ATP-driven drug secretion in renal proximal tubule. Mol Pharmacol 57: 59-67, 2000.
    • (2000) Mol Pharmacol , vol.57 , pp. 59-67
    • Masereeuw, R.1    Terlouw, S.A.2    van Aubel, R.A.3    Russel, F.G.4    Miller, D.S.5
  • 230
    • 0031589135 scopus 로고    scopus 로고
    • mRNA distribution and membrane localization of the OAT-K1 organic anion transporter in rat renal tubules
    • Masuda S, Saito H, Nonoguchi H, Tomita K, Inui K-I. mRNA distribution and membrane localization of the OAT-K1 organic anion transporter in rat renal tubules. FEBS Lett 407: 127-131, 1997.
    • (1997) FEBS Lett , vol.407 , pp. 127-131
    • Masuda, S.1    Saito, H.2    Nonoguchi, H.3    Tomita, K.4    Inui, K.-I.5
  • 234
    • 0020671931 scopus 로고
    • Procainamide uptake by rabbit proximal tubules
    • McKinney TD. Procainamide uptake by rabbit proximal tubules. J Pharmacol Exp Ther 224: 302-306, 1983.
    • (1983) J Pharmacol Exp Ther , vol.224 , pp. 302-306
    • McKinney, T.D.1
  • 235
    • 0021396520 scopus 로고
    • Further studies of organic base secretion by rabbit proximal tubules
    • McKinney TD. Further studies of organic base secretion by rabbit proximal tubules. Am J Physiol 246: F282-F289, 1984.
    • (1984) Am J Physiol , vol.246
    • McKinney, T.D.1
  • 236
    • 0019597010 scopus 로고
    • Cimetidine secretion by rabbit renal tubules in vitro
    • McKinney TD, Myers P, Speeg KV Jr. Cimetidine secretion by rabbit renal tubules in vitro. Am J Physiol 241: F69-F76, 1981.
    • (1981) Am J Physiol , vol.241
    • McKinney, T.D.1    Myers, P.2    Speeg Jr., K.V.3
  • 237
    • 0020149460 scopus 로고
    • Cimetidine and procainamide secretion by proximal tubules in vitro
    • McKinney TD, Speeg KV Jr. Cimetidine and procainamide secretion by proximal tubules in vitro. Am J Physiol 242: F672-F680, 1982.
    • (1982) Am J Physiol , vol.242
    • McKinney, T.D.1    Speeg Jr., K.V.2
  • 238
    • 66549096122 scopus 로고    scopus 로고
    • Regulatory role of testosterone in organic cation transport: In vivo and in vitro studies
    • Meetam P, Srimaroeng C, Soodvilai S, Chatsudthipong V. Regulatory role of testosterone in organic cation transport: In vivo and in vitro studies. Biol Pharm Bull 32: 982-987, 2009.
    • (2009) Biol Pharm Bull , vol.32 , pp. 982-987
    • Meetam, P.1    Srimaroeng, C.2    Soodvilai, S.3    Chatsudthipong, V.4
  • 240
    • 0025281139 scopus 로고
    • Carrier-mediated transport in the hepatic distribution and elimination of drugs, with special reference to the category of organic cations
    • Meijer DKF, Mol WEM, Müller M, Kurz G. Carrier-mediated transport in the hepatic distribution and elimination of drugs, with special reference to the category of organic cations. J Pharmacokinet Biopharm 18: 35-70, 1990.
    • (1990) J Pharmacokinet Biopharm , vol.18 , pp. 35-70
    • Meijer, D.K.F.1    Mol, W.E.M.2    Müller, M.3    Kurz, G.4
  • 243
    • 0031939970 scopus 로고    scopus 로고
    • Protein kinase C regulation of organic anion transport in renal proximal tubule
    • Miller DS. Protein kinase C regulation of organic anion transport in renal proximal tubule. Am J Physiol 274: F156-F164, 1998.
    • (1998) Am J Physiol , vol.274
    • Miller, D.S.1
  • 244
    • 0034765470 scopus 로고    scopus 로고
    • Nucleoside phosphonate interactions with multiple organic anion transporters in renal proximal tubule
    • Miller DS. Nucleoside phosphonate interactions with multiple organic anion transporters in renal proximal tubule. J Pharmacol Exp Ther 299: 567-574, 2001.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 567-574
    • Miller, D.S.1
  • 245
    • 0030867296 scopus 로고    scopus 로고
    • p-Glycoprotein-mediated transport of a fluorescent rapamycin derivative in renal proximal tubule
    • Miller DS, Fricker G, Drewe J. p-Glycoprotein-mediated transport of a fluorescent rapamycin derivative in renal proximal tubule. J Pharmacol Exp Ther 282: 440-444, 1997.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 440-444
    • Miller, D.S.1    Fricker, G.2    Drewe, J.3
  • 246
    • 0031730608 scopus 로고    scopus 로고
    • Protein kinase C regulation of p-glycoprotein-mediated xenobiotic secretion in renal proximal tubule
    • Miller DS, Sussman CR, Renfro JL. Protein kinase C regulation of p-glycoprotein-mediated xenobiotic secretion in renal proximal tubule. Am J Physiol 275: F785-F795, 1998.
    • (1998) Am J Physiol , vol.275
    • Miller, D.S.1    Sussman, C.R.2    Renfro, J.L.3
  • 247
    • 0024567003 scopus 로고
    • Multiple transport systems for organic cations in renal brush-border membrane vesicles
    • Miyamoto Y, Tiruppathi C, Ganapathy V, Leibach FH. Multiple transport systems for organic cations in renal brush-border membrane vesicles. Am J Physiol 256: F540-F548, 1989.
    • (1989) Am J Physiol , vol.256
    • Miyamoto, Y.1    Tiruppathi, C.2    Ganapathy, V.3    Leibach, F.H.4
  • 249
    • 34547921968 scopus 로고    scopus 로고
    • Pharmacophore modelling of stereoselective binding to the human organic cation transporter (hOCT1)
    • Moaddel R, Ravichandran S, Bighi F, Yamaguchi R, Wainer IW. Pharmacophore modelling of stereoselective binding to the human organic cation transporter (hOCT1). Br J Pharmacol 151: 1305-1314, 2007.
    • (2007) Br J Pharmacol , vol.151 , pp. 1305-1314
    • Moaddel, R.1    Ravichandran, S.2    Bighi, F.3    Yamaguchi, R.4    Wainer, I.W.5
  • 250
    • 0024435773 scopus 로고
    • Carriermediated transport of tetraethylammonium across rabbit renal basolateral membrane
    • Montrose-Rafizadeh C, Mingard F, Murer H, Roch-Ramel F. Carriermediated transport of tetraethylammonium across rabbit renal basolateral membrane. Am J Physiol 257: F243-F251, 1989.
    • (1989) Am J Physiol , vol.257
    • Montrose-Rafizadeh, C.1    Mingard, F.2    Murer, H.3    Roch-Ramel, F.4
  • 251
    • 0023642634 scopus 로고
    • Axial heterogeneity of organic cation transport along the rabbit renal proximal tubule: Studies with brush-border membrane vesicles
    • Montrose-Rafizadeh C, Roch-Ramel F, Schäli C. Axial heterogeneity of organic cation transport along the rabbit renal proximal tubule: Studies with brush-border membrane vesicles. Biochim Biophys Acta 904: 175-177, 1987.
    • (1987) Biochim Biophys Acta , vol.904 , pp. 175-177
    • Montrose-Rafizadeh, C.1    Roch-Ramel, F.2    Schäli, C.3
  • 252
    • 0026442692 scopus 로고
    • Organic cation transport by rat liver plasma membrane vesicles: Studies with tetraethylammonium
    • Moseley RH, Jarose SM, Permoad P. Organic cation transport by rat liver plasma membrane vesicles: Studies with tetraethylammonium. Am J Physiol 263: G775-G785, 1992.
    • (1992) Am J Physiol , vol.263
    • Moseley, R.H.1    Jarose, S.M.2    Permoad, P.3
  • 253
    • 0025681666 scopus 로고
    • 1-methylnicotinamide by organic cation-proton exchange in rat liver membrane vesicles
    • 1-methylnicotinamide by organic cation-proton exchange in rat liver membrane vesicles. Am J Physiol 259: G973-G982, 1990.
    • (1990) Am J Physiol , vol.259
    • Moseley, R.H.1    Morrissette, J.2    Johnson, T.R.3
  • 257
    • 78650936423 scopus 로고    scopus 로고
    • Analysis of 3-dimensional systems for developing and mature kidney clarifies the role of OAT1 and OAT3 in antiviral handling
    • NagleMA, Truong DM, Dnyanmote AV, Eraly SA, Wu W, Nigam SK. Analysis of 3-dimensional systems for developing and mature kidney clarifies the role of OAT1 and OAT3 in antiviral handling. J Biol Chem 286: 243-251, 2010.
    • (2010) J Biol Chem , vol.286 , pp. 243-251
    • Nagle, M.A.1    Truong, D.M.2    Dnyanmote, A.V.3    Eraly, S.A.4    Wu, W.5    Nigam, S.K.6
  • 258
    • 77957929019 scopus 로고    scopus 로고
    • Disruption of multidrug and toxin extrusion MATE1 potentiates cisplatin-induced nephrotoxicity
    • Nakamura T, Yonezawa A, Hashimoto S, Katsura T, Inui KI. Disruption of multidrug and toxin extrusion MATE1 potentiates cisplatin-induced nephrotoxicity. Biochem Pharmacol 80: 1762-1767, 2010.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1762-1767
    • Nakamura, T.1    Yonezawa, A.2    Hashimoto, S.3    Katsura, T.4    Inui, K.I.5
  • 259
    • 34548103493 scopus 로고    scopus 로고
    • Role of OATP transporters in the disposition of drugs
    • Niemi M. Role of OATP transporters in the disposition of drugs. Pharmacogenomics 8: 787-802, 2007.
    • (2007) Pharmacogenomics , vol.8 , pp. 787-802
    • Niemi, M.1
  • 260
    • 33846706434 scopus 로고    scopus 로고
    • The apical conjugate efflux pump ABCC2 (MRP2)
    • Nies AT, Keppler D. The apical conjugate efflux pump ABCC2 (MRP2). Pflugers Arch 453: 643-659, 2007.
    • (2007) Pflugers Arch , vol.453 , pp. 643-659
    • Nies, A.T.1    Keppler, D.2
  • 261
    • 78649646556 scopus 로고    scopus 로고
    • Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy
    • NiesAT, Koepsell H, Damme K, Schwab M. Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy. Handb Exp Pharmacol 201: 105-167, 2011.
    • (2011) Handb Exp Pharmacol , vol.201 , pp. 105-167
    • Nies, A.T.1    Koepsell, H.2    Damme, K.3    Schwab, M.4
  • 262
    • 27144448793 scopus 로고    scopus 로고
    • Short-term exposure of renal proximal tubules to gentamicin increases long-term multidrug resistance protein 2 (Abcc2) transport function and reduces nephrotoxicant sensitivity
    • Notenboom S, Miller DS, Kuik LH, Smits P, Russel FG, Masereeuw R. Short-term exposure of renal proximal tubules to gentamicin increases long-term multidrug resistance protein 2 (Abcc2) transport function and reduces nephrotoxicant sensitivity. J Pharmacol Exp Ther 315: 912-920, 2005.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 912-920
    • Notenboom, S.1    Miller, D.S.2    Kuik, L.H.3    Smits, P.4    Russel, F.G.5    Masereeuw, R.6
  • 264
    • 2942690045 scopus 로고    scopus 로고
    • Involvement of guanylyl cyclase and cGMP in the regulation ofMrp2-mediated transport in the proximal tubule
    • Notenboom S, Miller DS, Smits P, Russel FG, Masereeuw R. Involvement of guanylyl cyclase and cGMP in the regulation ofMrp2-mediated transport in the proximal tubule. Am J Physiol Renal Physiol 287: F33-F38, 2004.
    • (2004) Am J Physiol Renal Physiol , vol.287
    • Notenboom, S.1    Miller, D.S.2    Smits, P.3    Russel, F.G.4    Masereeuw, R.5
  • 265
    • 33747624408 scopus 로고    scopus 로고
    • Increased apical insertion of the multidrug resistance protein 2 (MRP2/ABCC2) in renal proximal tubules following gentamicin exposure
    • Notenboom S, Wouterse AC, Peters B, Kuik LH, Heemskerk S, Russel FG, Masereeuw R. Increased apical insertion of the multidrug resistance protein 2 (MRP2/ABCC2) in renal proximal tubules following gentamicin exposure. J Pharmacol Exp Ther 318: 1194-1202, 2006.
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 1194-1202
    • Notenboom, S.1    Wouterse, A.C.2    Peters, B.3    Kuik, L.H.4    Heemskerk, S.5    Russel, F.G.6    Masereeuw, R.7
  • 267
    • 0037375474 scopus 로고    scopus 로고
    • Selection and characterization of the choline transport mutation suppressor from Torpedo electric lobe, CTL1
    • O'Regan S, Meunier FM. Selection and characterization of the choline transport mutation suppressor from Torpedo electric lobe, CTL1. Neurochem Res 28: 551-555, 2003.
    • (2003) Neurochem Res , vol.28 , pp. 551-555
    • O'Regan, S.1    Meunier, F.M.2
  • 268
    • 0034652249 scopus 로고    scopus 로고
    • An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins
    • O'Regan S, Traiffort E, Ruat M, Cha N, Compaore D, Meunier FM. An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins. Proc Natl Acad Sci U S A 97: 1835-1840, 2000.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1835-1840
    • O'Regan, S.1    Traiffort, E.2    Ruat, M.3    Cha, N.4    Compaore, D.5    Meunier, F.M.6
  • 269
    • 33749030747 scopus 로고    scopus 로고
    • Human organic anion transporter 3 gene is regulated constitutively and inducibly via a cAMP-response element
    • Ogasawara K, Terada T, Asaka J, Katsura T, Inui K. Human organic anion transporter 3 gene is regulated constitutively and inducibly via a cAMP-response element. J Pharmacol Exp Ther 319: 317-322, 2006.
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 317-322
    • Ogasawara, K.1    Terada, T.2    Asaka, J.3    Katsura, T.4    Inui, K.5
  • 270
    • 34447634890 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-4aregulates the human organic anion transporter 1 gene in the kidney
    • Ogasawara K, Terada T, Asaka J, Katsura T, Inui K. Hepatocyte nuclear factor-4αregulates the human organic anion transporter 1 gene in the kidney. Am J Physiol Renal Physiol 292: F1819-F1826, 2007.
    • (2007) Am J Physiol Renal Physiol , vol.292
    • Ogasawara, K.1    Terada, T.2    Asaka, J.3    Katsura, T.4    Inui, K.5
  • 271
  • 273
    • 0030590117 scopus 로고    scopus 로고
    • cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2
    • Okuda M, Saito H, Urakami Y, Takano M, Inui K-I. cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2. Biochem Biophys Res Comm 224: 500-507, 1996.
    • (1996) Biochem Biophys Res Comm , vol.224 , pp. 500-507
    • Okuda, M.1    Saito, H.2    Urakami, Y.3    Takano, M.4    Inui, K.-I.5
  • 274
    • 0037375481 scopus 로고    scopus 로고
    • High-affinity choline transporter
    • Okuda T, Haga T. High-affinity choline transporter. Neurochem Res 28: 483-488, 2003.
    • (2003) Neurochem Res , vol.28 , pp. 483-488
    • Okuda, T.1    Haga, T.2
  • 275
    • 33749988040 scopus 로고    scopus 로고
    • TheMATE proteins as fundamental transporters of metabolic and xenobiotic organic cations
    • Omote H, HiasaM, Matsumoto T, Otsuka M, Moriyama Y. TheMATE proteins as fundamental transporters of metabolic and xenobiotic organic cations. Trends Pharmacol Sci 27: 587-593, 2006.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 587-593
    • Omote, H.1    Hiasa, M.2    Matsumoto, T.3    Otsuka, M.4    Moriyama, Y.5
  • 277
    • 14244266607 scopus 로고    scopus 로고
    • Identification of essential amino acid residues of the NorM Na+/multidrug antiporter in Vibrio parahaemolyticus
    • Otsuka M, Yasuda M, Morita Y, Otsuka C, Tsuchiya T, Omote H, Moriyama Y. Identification of essential amino acid residues of the NorM Na+/multidrug antiporter in Vibrio parahaemolyticus. J Bacteriol 187: 1552-1558, 2005.
    • (2005) J Bacteriol , vol.187 , pp. 1552-1558
    • Otsuka, M.1    Yasuda, M.2    Morita, Y.3    Otsuka, C.4    Tsuchiya, T.5    Omote, H.6    Moriyama, Y.7
  • 278
    • 0026015282 scopus 로고
    • Organic cation transport in human renal brush-border membrane vesicles
    • Ott RJ, Hui AC, Yuan G, Giacomini KM. Organic cation transport in human renal brush-border membrane vesicles. Am J Physiol 261: F443-F451, 1991.
    • (1991) Am J Physiol , vol.261
    • Ott, R.J.1    Hui, A.C.2    Yuan, G.3    Giacomini, K.M.4
  • 281
    • 0033104810 scopus 로고    scopus 로고
    • Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione
    • Paulusma CC, van Geer MA, Evers R, Heijn M, Ottenhoff R, Borst P, Oude Elferink RP. Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione. Biochem J 338: 393-401, 1999.
    • (1999) Biochem J , vol.338 , pp. 393-401
    • Paulusma, C.C.1    van Geer, M.A.2    Evers, R.3    Heijn, M.4    Ottenhoff, R.5    Borst, P.6    Oude Elferink, R.P.7
  • 282
    • 34247849190 scopus 로고    scopus 로고
    • Inorganic mercury interacts with cysteine residues (C451 and C474) of hOCT2 to reduce its transport activity
    • Pelis RM, Dangprapai Y, Wunz TM, Wright SH. Inorganic mercury interacts with cysteine residues (C451 and C474) of hOCT2 to reduce its transport activity. Am J Physiol Renal Physiol 292: F1583-F1591, 2007.
    • (2007) Am J Physiol Renal Physiol , vol.292
    • Pelis, R.M.1    Dangprapai, Y.2    Wunz, T.M.3    Wright, S.H.4
  • 283
    • 35549012391 scopus 로고    scopus 로고
    • Influence of estrogen and xenoestrogens on basolateral uptake of tetraethylammonium by opossum kidney cells in culture
    • Pelis RM, Hartman RC, Wright SH, Wunz TM, Groves CE. Influence of estrogen and xenoestrogens on basolateral uptake of tetraethylammonium by opossum kidney cells in culture. J Pharmacol Exp Ther 323: 555-561, 2007.
    • (2007) J Pharmacol Exp Ther , vol.323 , pp. 555-561
    • Pelis, R.M.1    Hartman, R.C.2    Wright, S.H.3    Wunz, T.M.4    Groves, C.E.5
  • 284
    • 33646565671 scopus 로고    scopus 로고
    • Functional influence of Nglycosylation in OCT2-mediated tetraethylammonium transport
    • Pelis RM, Suhre WM, Wright SH. Functional influence of Nglycosylation in OCT2-mediated tetraethylammonium transport. Am J Physiol Renal Physiol 290: F1118-F1126, 2006.
    • (2006) Am J Physiol Renal Physiol , vol.290
    • Pelis, R.M.1    Suhre, W.M.2    Wright, S.H.3
  • 285
    • 33845922107 scopus 로고    scopus 로고
    • Cysteine accessibility in the hydrophilic cleft of the human organic cation transporter 2
    • Pelis RM, Zhang X, Dangprapai Y, Wright SH. Cysteine accessibility in the hydrophilic cleft of the human organic cation transporter 2. J Biol Chem 281: 35272-35280, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 35272-35280
    • Pelis, R.M.1    Zhang, X.2    Dangprapai, Y.3    Wright, S.H.4
  • 287
    • 33846010171 scopus 로고    scopus 로고
    • Athree-dimensional model of human organic anion transporter 1: Aromatic amino acids required for substrate transport
    • Perry JL, Dembla-Rajpal N, Hall LA, Pritchard JB. Athree-dimensional model of human organic anion transporter 1: Aromatic amino acids required for substrate transport. J Biol Chem 281: 38071-38079, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 38071-38079
    • Perry, J.L.1    Dembla-Rajpal, N.2    Hall, L.A.3    Pritchard, J.B.4
  • 288
    • 0009600384 scopus 로고
    • Effect of 20, 60 and 120 minutes of renal ischemia on glomerular and tubular function
    • Phillips RA, Hamilton PB. Effect of 20, 60 and 120 minutes of renal ischemia on glomerular and tubular function. Am J Physiol 152, 523-530, 1948.
    • (1948) Am J Physiol , vol.152 , pp. 523-530
    • Phillips, R.A.1    Hamilton, P.B.2
  • 289
    • 0035823636 scopus 로고    scopus 로고
    • Properties and regulation of organic cation transport in freshly isolated human proximal tubules
    • Pietig G, Mehrens T, Hirsch JR, Cetinkaya I, Piechota H, Schlatter E. Properties and regulation of organic cation transport in freshly isolated human proximal tubules. J Biol Chem 276: 33741-33746, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 33741-33746
    • Pietig, G.1    Mehrens, T.2    Hirsch, J.R.3    Cetinkaya, I.4    Piechota, H.5    Schlatter, E.6
  • 290
    • 0027476664 scopus 로고
    • Uric acid transport in rat renal basolateral vesicles
    • Polkowski CA, Grassl SM. Uric acid transport in rat renal basolateral vesicles. Biochim Biophys Acta 1146: 145-152, 1993.
    • (1993) Biochim Biophys Acta , vol.1146 , pp. 145-152
    • Polkowski, C.A.1    Grassl, S.M.2
  • 291
    • 17844385785 scopus 로고    scopus 로고
    • The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4a and suppressed by bile acids
    • Popowski K, Eloranta JJ, Saborowski M, Fried M, Meier PJ, Kullak-Ublick GA. The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4α and suppressed by bile acids. Mol Pharmacol 67: 1629-1638, 2005.
    • (2005) Mol Pharmacol , vol.67 , pp. 1629-1638
    • Popowski, K.1    Eloranta, J.J.2    Saborowski, M.3    Fried, M.4    Meier, P.J.5    Kullak-Ublick, G.A.6
  • 292
    • 17644411713 scopus 로고    scopus 로고
    • Amino acids critical for substrate affinity of rat organic cation transporter 1 line the substrate binding region in a model derived from the tertiary structure of lactose permease
    • Popp C, Gorboulev V, Muller TD, Gorbunov D, Shatskaya N, Koepsell H. Amino acids critical for substrate affinity of rat organic cation transporter 1 line the substrate binding region in a model derived from the tertiary structure of lactose permease. Mol Pharmacol 67: 1600-1611, 2005.
    • (2005) Mol Pharmacol , vol.67 , pp. 1600-1611
    • Popp, C.1    Gorboulev, V.2    Muller, T.D.3    Gorbunov, D.4    Shatskaya, N.5    Koepsell, H.6
  • 293
    • 33644847437 scopus 로고    scopus 로고
    • Kinetic validation of the use of carboxydichlorofluorescein as a drug surrogate for MRP5-mediated transport
    • Pratt S, Chen V, Perry WI III, Starling JJ, Dantzig AH. Kinetic validation of the use of carboxydichlorofluorescein as a drug surrogate for MRP5-mediated transport. Eur J Pharm Sci 27: 524-532, 2006.
    • (2006) Eur J Pharm Sci , vol.27 , pp. 524-532
    • Pratt, S.1    Chen, V.2    Perry III, W.I.3    Starling, J.J.4    Dantzig, A.H.5
  • 294
    • 0023663532 scopus 로고
    • Luminal and peritubular steps in the renal transport of p-aminohippurate
    • Pritchard JB. Luminal and peritubular steps in the renal transport of p-aminohippurate. Biochim Biophys Acta 906: 295-308, 1987.
    • (1987) Biochim Biophys Acta , vol.906 , pp. 295-308
    • Pritchard, J.B.1
  • 295
    • 0023765854 scopus 로고
    • Coupled transport of p-aminohippurate by rat kidney basolateral membrane vesicles
    • Pritchard JB. Coupled transport of p-aminohippurate by rat kidney basolateral membrane vesicles. Am J Physiol 255: F597-F604, 1988.
    • (1988) Am J Physiol , vol.255
    • Pritchard, J.B.1
  • 296
    • 0027133590 scopus 로고
    • Mechanisms mediating renal secretion of organic anions and cations
    • Pritchard JB, Miller DS. Mechanisms mediating renal secretion of organic anions and cations. Physiol Rev 73: 765-796, 1993.
    • (1993) Physiol Rev , vol.73 , pp. 765-796
    • Pritchard, J.B.1    Miller, D.S.2
  • 297
    • 0029902695 scopus 로고    scopus 로고
    • Renal secretion of organic anions and cations
    • Pritchard JB, Miller DS. Renal secretion of organic anions and cations. Kidney Int 49: 1649-1654, 1996.
    • (1996) Kidney Int , vol.49 , pp. 1649-1654
    • Pritchard, J.B.1    Miller, D.S.2
  • 299
    • 0033574034 scopus 로고    scopus 로고
    • Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3)
    • Race JE, Grassl SM, Williams WJ, Holtzman EJ. Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3). Biochem Biophys Res Commun 255: 508-514, 1999.
    • (1999) Biochem Biophys Res Commun , vol.255 , pp. 508-514
    • Race, J.E.1    Grassl, S.M.2    Williams, W.J.3    Holtzman, E.J.4
  • 300
    • 84940130257 scopus 로고
    • Tetraethylammonium and p-aminohippurate as clearance markers for renal plasma flow in the rat during saline and glucose infusion
    • Rasmussen SN, ShalmiM, HansenM, Christensen S. Tetraethylammonium and p-aminohippurate as clearance markers for renal plasma flow in the rat during saline and glucose infusion. Ren Physiol Biochem 13: 314-323, 1990.
    • (1990) Ren Physiol Biochem , vol.13 , pp. 314-323
    • Rasmussen, S.N.1    Shalmi, M.2    Hansen, M.3    Christensen, S.4
  • 301
    • 33750958330 scopus 로고    scopus 로고
    • Highdose methotrexate in pediatric acute lymphoblastic leukemia: Impact of ABCC2 polymorphisms on plasma concentrations
    • Rau T, Erney B, Gores R, Eschenhagen T, Beck J, Langer T. Highdose methotrexate in pediatric acute lymphoblastic leukemia: Impact of ABCC2 polymorphisms on plasma concentrations. Clin Pharmacol Ther 80: 468-476, 2006.
    • (2006) Clin Pharmacol Ther , vol.80 , pp. 468-476
    • Rau, T.1    Erney, B.2    Gores, R.3    Eschenhagen, T.4    Beck, J.5    Langer, T.6
  • 302
    • 44649096868 scopus 로고    scopus 로고
    • Molecular model of the outward facing state of the human multidrug resistance protein 4 (MRP4/ABCC4)
    • Ravna AW, Sager G. Molecular model of the outward facing state of the human multidrug resistance protein 4 (MRP4/ABCC4). BioorgMed Chem Lett 18: 3481-3483, 2008.
    • (2008) BioorgMed Chem Lett , vol.18 , pp. 3481-3483
    • Ravna, A.W.1    Sager, G.2
  • 303
  • 304
    • 0043132421 scopus 로고    scopus 로고
    • The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs
    • Reid G, Wielinga P, Zelcer N, van der Heijden I, Kuil A, de Haas M, Wijnholds J, Borst P. The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Proc Natl Acad Sci U S A 100: 9244-9249, 2003.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9244-9249
    • Reid, G.1    Wielinga, P.2    Zelcer, N.3    van der Heijden, I.4    Kuil, A.5    de Haas, M.6    Wijnholds, J.7    Borst, P.8
  • 307
    • 0344295982 scopus 로고
    • Stop-flow localization of renal tubular excretion of tetraethylammonium
    • Rennick B, Moe GK. Stop-flow localization of renal tubular excretion of tetraethylammonium. Am J Physiol 198: 1267-1270, 1960.
    • (1960) Am J Physiol , vol.198 , pp. 1267-1270
    • Rennick, B.1    Moe, G.K.2
  • 309
    • 37349081408 scopus 로고    scopus 로고
    • ATP-dependent transport of leukotrienes B4 and C4 by the multidrug resistance protein ABCC4 (MRP4)
    • Rius M, Hummel-Eisenbeiss J, Keppler D. ATP-dependent transport of leukotrienes B4 and C4 by the multidrug resistance protein ABCC4 (MRP4). J Pharmacol Exp Ther 324: 86-94, 2008.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 86-94
    • Rius, M.1    Hummel-Eisenbeiss, J.2    Keppler, D.3
  • 310
    • 33847139479 scopus 로고    scopus 로고
    • Organic anion transporters of the SLC22 family: Biopharmaceutical, physiological, and pathological roles
    • Rizwan AN, Burckhardt G. Organic anion transporters of the SLC22 family: Biopharmaceutical, physiological, and pathological roles. Pharm Res 24: 450-470, 2007.
    • (2007) Pharm Res , vol.24 , pp. 450-470
    • Rizwan, A.N.1    Burckhardt, G.2
  • 311
    • 34250318936 scopus 로고    scopus 로고
    • The chloride dependence of the human organic anion transporter 1 (hOAT1) is blunted by mutation of a single amino acid
    • Rizwan AN, Krick W, Burckhardt G. The chloride dependence of the human organic anion transporter 1 (hOAT1) is blunted by mutation of a single amino acid. J Biol Chem 282: 13402-13409, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 13402-13409
    • Rizwan, A.N.1    Krick, W.2    Burckhardt, G.3
  • 312
    • 0001097160 scopus 로고
    • Renal excretion and tubular transport of organic anions and cations
    • Windhager EE, editor. New York: Oxford Univ. Press
    • Roch-Ramel F, Besseghir K, Murer H. Renal excretion and tubular transport of organic anions and cations. In: Windhager EE, editor. Handbook of Physiology. Section 8. Renal Physiology, Vol. II. New York: Oxford Univ. Press, 1992.
    • (1992) Handbook of Physiology. Section 8. Renal Physiology , vol.2
    • Roch-Ramel, F.1    Besseghir, K.2    Murer, H.3
  • 313
    • 0030041746 scopus 로고    scopus 로고
    • Indirect coupling of urate and paminohippurate transport to sodium in human brush-border membrane vesicles
    • Roch-Ramel F, Guisan B, Schild L. Indirect coupling of urate and paminohippurate transport to sodium in human brush-border membrane vesicles. Am J Physiol 270: F61-F68, 1996.
    • (1996) Am J Physiol , vol.270
    • Roch-Ramel, F.1    Guisan, B.2    Schild, L.3
  • 314
    • 0028300464 scopus 로고
    • Urate transport in brush-border membrane of human kidney
    • Roch-Ramel F, Werner D, Guisan B. Urate transport in brush-border membrane of human kidney. Am J Physiol 266: F797-F805, 1994.
    • (1994) Am J Physiol , vol.266
    • Roch-Ramel, F.1    Werner, D.2    Guisan, B.3
  • 315
    • 0023499844 scopus 로고
    • Interaction of steadystate procainamide with H2-receptor antagonists cimetidine and ranitidine
    • Rodvold KA, Paloucek FP, Jung D, Gallastegui J. Interaction of steadystate procainamide with H2-receptor antagonists cimetidine and ranitidine. Ther Drug Monit 9: 378-383, 1987.
    • (1987) Ther Drug Monit , vol.9 , pp. 378-383
    • Rodvold, K.A.1    Paloucek, F.P.2    Jung, D.3    Gallastegui, J.4
  • 316
    • 41349107158 scopus 로고    scopus 로고
    • Multidrug resistance protein 4 (MRP4/ABCC4): A versatile efflux transporter for drugs and signalling molecules
    • Russel FG, Koenderink JB, Masereeuw R. Multidrug resistance protein 4 (MRP4/ABCC4): A versatile efflux transporter for drugs and signalling molecules. Trends Pharmacol Sci 29: 200-207, 2008.
    • (2008) Trends Pharmacol Sci , vol.29 , pp. 200-207
    • Russel, F.G.1    Koenderink, J.B.2    Masereeuw, R.3
  • 319
    • 0034671544 scopus 로고    scopus 로고
    • Identification of basic residues involved in drug export function of human multidrug resistance-associated protein 2
    • Ryu S, Kawabe T, Nada S, Yamaguchi A. Identification of basic residues involved in drug export function of human multidrug resistance-associated protein 2. J Biol Chem 275: 39617-39624, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 39617-39624
    • Ryu, S.1    Kawabe, T.2    Nada, S.3    Yamaguchi, A.4
  • 320
    • 72049089059 scopus 로고    scopus 로고
    • Pathophysiological regulation of renal SLC22A organic ion transporters in acute kidney injury: Pharmacological and toxicological implications
    • Saito H. Pathophysiological regulation of renal SLC22A organic ion transporters in acute kidney injury: Pharmacological and toxicological implications. Pharmacol Ther 125: 79-91, 2010.
    • (2010) Pharmacol Ther , vol.125 , pp. 79-91
    • Saito, H.1
  • 321
    • 38749113889 scopus 로고    scopus 로고
    • Transcriptional regulation of human and mouse organic anion transporter 1 by hepatocyte nuclear factor 1 a/b
    • Saji T, Kikuchi R, Kusuhara H, Kim I, Gonzalez FJ, Sugiyama Y. Transcriptional regulation of human and mouse organic anion transporter 1 by hepatocyte nuclear factor 1 α/β. J Pharmacol Exp Ther 324: 784-790, 2008.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 784-790
    • Saji, T.1    Kikuchi, R.2    Kusuhara, H.3    Kim, I.4    Gonzalez, F.J.5    Sugiyama, Y.6
  • 323
    • 77649212118 scopus 로고    scopus 로고
    • Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7) in human
    • Sato M, Mamada H, Anzai N, Shirasaka Y, Nakanishi T, Tamai I. Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7) in human. Biol Pharm Bull 33: 498-503, 2010.
    • (2010) Biol Pharm Bull , vol.33 , pp. 498-503
    • Sato, M.1    Mamada, H.2    Anzai, N.3    Shirasaka, Y.4    Nakanishi, T.5    Tamai, I.6
  • 324
    • 51249105551 scopus 로고    scopus 로고
    • Transcellular transport of organic cations in double-transfectedMDCKcells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1
    • Sato T, Masuda S, Yonezawa A, Tanihara Y, Katsura T, Inui K. Transcellular transport of organic cations in double-transfectedMDCKcells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1. Biochem Pharmacol 76: 894-903, 2008.
    • (2008) Biochem Pharmacol , vol.76 , pp. 894-903
    • Sato, T.1    Masuda, S.2    Yonezawa, A.3    Tanihara, Y.4    Katsura, T.5    Inui, K.6
  • 325
    • 1642376462 scopus 로고    scopus 로고
    • Action of EGF and PGE2 on basolateral organic anion uptake in rabbit proximal renal tubules and hOAT1 expressed in human kidney epithelial cells
    • Sauvant C, Hesse D, Holzinger H, Evans KK, Dantzler WH, Gekle M. Action of EGF and PGE2 on basolateral organic anion uptake in rabbit proximal renal tubules and hOAT1 expressed in human kidney epithelial cells. Am J Physiol Renal Physiol 286: F774-F783, 2004.
    • (2004) Am J Physiol Renal Physiol , vol.286
    • Sauvant, C.1    Hesse, D.2    Holzinger, H.3    Evans, K.K.4    Dantzler, W.H.5    Gekle, M.6
  • 326
    • 0036066084 scopus 로고    scopus 로고
    • Short-term regulation of basolateral organic anion uptake in proximal tubularOKcells: EGFacts viaMAPK, PLA(2), and COX1
    • Sauvant C, Holzinger H, Gekle M. Short-term regulation of basolateral organic anion uptake in proximal tubularOKcells: EGFacts viaMAPK, PLA(2), and COX1. J Am Soc Nephrol 13: 1981-1991, 2002.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1981-1991
    • Sauvant, C.1    Holzinger, H.2    Gekle, M.3
  • 328
    • 33645457811 scopus 로고    scopus 로고
    • Prostaglandin E2 inhibits its own renal transport by downregulation of organic anion transporters rOAT1 and rOAT3
    • Sauvant C, Holzinger H, Gekle M. Prostaglandin E2 inhibits its own renal transport by downregulation of organic anion transporters rOAT1 and rOAT3. J Am Soc Nephrol 17: 46-53, 2006.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 46-53
    • Sauvant, C.1    Holzinger, H.2    Gekle, M.3
  • 329
    • 0020807541 scopus 로고
    • Secretion of tetraethylammonium by proximal tubules of rabbit kidneys
    • Schäli C, Schild L, Overney J, Roch-Ramel F. Secretion of tetraethylammonium by proximal tubules of rabbit kidneys. Am J Physiol 245: F238-F246, 1983.
    • (1983) Am J Physiol , vol.245
    • Schäli, C.1    Schild, L.2    Overney, J.3    Roch-Ramel, F.4
  • 331
    • 0030832802 scopus 로고    scopus 로고
    • Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules
    • Schaub TP, Kartenbeck J, König J, Vogel O, Witzgall R, Kriz W, Keppler D. Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules. J Am Soc Nephrol 8: 1213-1221, 1997.
    • (1997) J Am Soc Nephrol , vol.8 , pp. 1213-1221
    • Schaub, T.P.1    Kartenbeck, J.2    König, J.3    Vogel, O.4    Witzgall, R.5    Kriz, W.6    Keppler, D.7
  • 332
    • 57849133538 scopus 로고    scopus 로고
    • New therapeutic approaches in type 2 diabetes
    • Scheen AJ. New therapeutic approaches in type 2 diabetes. Acta Clin Belg 63: 402-407, 2008.
    • (2008) Acta Clin Belg , vol.63 , pp. 402-407
    • Scheen, A.J.1
  • 334
    • 34249989197 scopus 로고    scopus 로고
    • Extraneuronal monoamine transporter and organic cation transporters 1 and 2: A review of transport efficiency
    • Schomig E, Lazar A, Grundemann D. Extraneuronal monoamine transporter and organic cation transporters 1 and 2: A review of transport efficiency. Handb Exp Pharmacol 175: 151-180, 2006.
    • (2006) Handb Exp Pharmacol , vol.175 , pp. 151-180
    • Schomig, E.1    Lazar, A.2    Grundemann, D.3
  • 337
    • 0030855487 scopus 로고    scopus 로고
    • Expression cloning and characterization of a novel multispecific organic anion transporter
    • Sekine T, Watanabe N, Hosoyamada M, Kanaim Y, Endou H. Expression cloning and characterization of a novel multispecific organic anion transporter. J Biol Chem 272: 18526-18529, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 18526-18529
    • Sekine, T.1    Watanabe, N.2    Hosoyamada, M.3    Kanaim, Y.4    Endou, H.5
  • 338
    • 33846385587 scopus 로고    scopus 로고
    • Mammalian cytochromes P450-importance of tissue specificity
    • Seliskar M, Rozman D. Mammalian cytochromes P450-importance of tissue specificity. Biochim Biophys Acta 1770: 458-466, 2007.
    • (2007) Biochim Biophys Acta , vol.1770 , pp. 458-466
    • Seliskar, M.1    Rozman, D.2
  • 339
    • 0015452604 scopus 로고
    • Renal handling of phenol red. I. A comparative study on the accumulation of phenol red and p-aminohippurate in rabbit kidney tubules in vitro
    • Sheikh MI. Renal handling of phenol red. I. A comparative study on the accumulation of phenol red and p-aminohippurate in rabbit kidney tubules in vitro. J Physiol 227: 565-590, 1972.
    • (1972) J Physiol , vol.227 , pp. 565-590
    • Sheikh, M.I.1
  • 341
    • 33846617263 scopus 로고    scopus 로고
    • Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin
    • Shikata E, Yamamoto R, Takane H, Shigemasa C, Ikeda T, Otsubo K, Ieiri I. Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin. J Hum Genet 52: 117-122, 2007.
    • (2007) J Hum Genet , vol.52 , pp. 117-122
    • Shikata, E.1    Yamamoto, R.2    Takane, H.3    Shigemasa, C.4    Ikeda, T.5    Otsubo, K.6    Ieiri, I.7
  • 343
    • 0023514358 scopus 로고
    • Indirect coupling to Na+ of paminohippuric acid uptake into rat renal basolateral membrane vesicles
    • Shimada H, Moewes B, Burckhardt G. Indirect coupling to Na+ of paminohippuric acid uptake into rat renal basolateral membrane vesicles. Am J Physiol 253: F795-F801, 1987.
    • (1987) Am J Physiol , vol.253
    • Shimada, H.1    Moewes, B.2    Burckhardt, G.3
  • 347
    • 0033964120 scopus 로고    scopus 로고
    • PKC regulation of organic anion secretion in perfused S2 segments of rabbit proximal tubules
    • Shuprisha A, Lynch RM, Wright SH, Dantzler WH. PKC regulation of organic anion secretion in perfused S2 segments of rabbit proximal tubules. Am J Physiol 278: F104-F109, 2000.
    • (2000) Am J Physiol , vol.278
    • Shuprisha, A.1    Lynch, R.M.2    Wright, S.H.3    Dantzler, W.H.4
  • 348
    • 0033696184 scopus 로고    scopus 로고
    • Method for measuring luminal efflux of fluorescent organic compounds in isolated, perfused renal tubules
    • Shuprisha A, Wright SH, Dantzler WH. Method for measuring luminal efflux of fluorescent organic compounds in isolated, perfused renal tubules. Am J Physiol Renal Physiol 279: F960-F964, 2000.
    • (2000) Am J Physiol Renal Physiol , vol.279
    • Shuprisha, A.1    Wright, S.H.2    Dantzler, W.H.3
  • 349
    • 33745448916 scopus 로고    scopus 로고
    • OCTNs:Will the real IBD5 gene please stand up?
    • Silverberg MS. OCTNs:Will the real IBD5 gene please stand up? World J Gastroenterol 12: 3678-3681, 2006.
    • (2006) World J Gastroenterol , vol.12 , pp. 3678-3681
    • Silverberg, M.S.1
  • 350
    • 0036146331 scopus 로고    scopus 로고
    • Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels
    • Slitt AL, Cherrington NJ, Hartley DP, Leazer TM, Klaassen CD. Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels. Drug Metab Dispos 30: 212-219, 2002.
    • (2002) Drug Metab Dispos , vol.30 , pp. 212-219
    • Slitt, A.L.1    Cherrington, N.J.2    Hartley, D.P.3    Leazer, T.M.4    Klaassen, C.D.5
  • 351
    • 12144269640 scopus 로고    scopus 로고
    • Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter
    • Smeets PH, van Aubel RA, Wouterse AC, Van Den Heuvel JJ, Russel FG. Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter. J Am Soc Nephrol 15: 2828-2835, 2004.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2828-2835
    • Smeets, P.H.1    van Aubel, R.A.2    Wouterse, A.C.3    Van Den Heuvel, J.J.4    Russel, F.G.5
  • 352
    • 0023680901 scopus 로고
    • Membrane potential drives organic cation transport into teleost renal proximal tubules
    • Smith PM, Pritchard JB, Miller DS. Membrane potential drives organic cation transport into teleost renal proximal tubules. Am J Physiol 255: R492-R499, 1988.
    • (1988) Am J Physiol , vol.255
    • Smith, P.M.1    Pritchard, J.B.2    Miller, D.S.3
  • 353
    • 0025054179 scopus 로고
    • Effect of endogenous and exogenous polyamines on organic cation transport in rabbit renal plasma membrane vesicles
    • Sokol PP, Gates SB. Effect of endogenous and exogenous polyamines on organic cation transport in rabbit renal plasma membrane vesicles. J Pharmacol Exp Ther 255: 52-58, 1990.
    • (1990) J Pharmacol Exp Ther , vol.255 , pp. 52-58
    • Sokol, P.P.1    Gates, S.B.2
  • 354
    • 0022263070 scopus 로고
    • Electroneutral transport of organic cations in canine renal brush border membrane vesicles (BBMV)
    • Sokol PP, Holohan PD, Ross CR. Electroneutral transport of organic cations in canine renal brush border membrane vesicles (BBMV). J Pharmacol Exp Ther 233: 694-699, 1985.
    • (1985) J Pharmacol Exp Ther , vol.233 , pp. 694-699
    • Sokol, P.P.1    Holohan, P.D.2    Ross, C.R.3
  • 355
    • 0025285632 scopus 로고
    • Mechanism of organic cation transport in rabbit renal basolateral membrane vesicles
    • Sokol PP, McKinney TD. Mechanism of organic cation transport in rabbit renal basolateral membrane vesicles. Am J Physiol 258: F1599-F1607, 1990.
    • (1990) Am J Physiol , vol.258
    • Sokol, P.P.1    McKinney, T.D.2
  • 356
    • 0021133374 scopus 로고
    • Dose and concentration dependent effect of ranitidine on procainamide disposition and renal clearance in man
    • Somogyi A, Bochner F. Dose and concentration dependent effect of ranitidine on procainamide disposition and renal clearance in man. Br J clin Pharmacol 18: 175-181, 1984.
    • (1984) Br J clin Pharmacol , vol.18 , pp. 175-181
    • Somogyi, A.1    Bochner, F.2
  • 357
    • 0020488482 scopus 로고
    • Cimetidine reduces procainamide elimination
    • Somogyi A, Heinzow B. Cimetidine reduces procainamide elimination. New Eng J Med 307: 1080, 1982.
    • (1982) New Eng J Med , vol.307 , pp. 1080
    • Somogyi, A.1    Heinzow, B.2
  • 358
    • 0020635466 scopus 로고
    • Cimetidine-procainamide pharmacokinetic interaction on man: Evidence of competition for tubular secretion of basic drugs
    • Somogyi A, McLean A, Heinzow B. Cimetidine-procainamide pharmacokinetic interaction on man: Evidence of competition for tubular secretion of basic drugs. Eur J Clin Pharmacol 25: 339-345, 1983.
    • (1983) Eur J Clin Pharmacol , vol.25 , pp. 339-345
    • Somogyi, A.1    McLean, A.2    Heinzow, B.3
  • 360
    • 0030436862 scopus 로고    scopus 로고
    • Stereospecificity in contraluminal and luminal transporters of organic cations in the rat renal proximal tubule
    • Somogyi AA, Rumrich G, Fritzsch G, Ullrich KJ. Stereospecificity in contraluminal and luminal transporters of organic cations in the rat renal proximal tubule. J Pharmacol Exp Ther 278: 31-36, 1996.
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 31-36
    • Somogyi, A.A.1    Rumrich, G.2    Fritzsch, G.3    Ullrich, K.J.4
  • 361
    • 54249106729 scopus 로고    scopus 로고
    • Genetic variants of the organic cation transporter 2 influence the disposition of metformin
    • Song I, Shin H, Shim E, Jung I, Kim W, Shon J, Shin J. Genetic variants of the organic cation transporter 2 influence the disposition of metformin. Clin Pharmacol Ther 84: 559-562, 2008.
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 559-562
    • Song, I.1    Shin, H.2    Shim, E.3    Jung, I.4    Kim, W.5    Shon, J.6    Shin, J.7
  • 362
    • 50249136652 scopus 로고    scopus 로고
    • Genetic variants of organic cation transporter 2 (OCT2) significantly reduce metformin uptake in oocytes
    • Song IS, Shin HJ, Shin JG. Genetic variants of organic cation transporter 2 (OCT2) significantly reduce metformin uptake in oocytes. Xenobiotica 38: 1252-1262, 2008.
    • (2008) Xenobiotica , vol.38 , pp. 1252-1262
    • Song, I.S.1    Shin, H.J.2    Shin, J.G.3
  • 365
    • 48749084010 scopus 로고    scopus 로고
    • Physiology, structure, and regulation of the cloned organic anion transporters
    • Srimaroeng C, Perry JL, Pritchard JB. Physiology, structure, and regulation of the cloned organic anion transporters. Xenobiotica 38: 889-935, 2008.
    • (2008) Xenobiotica , vol.38 , pp. 889-935
    • Srimaroeng, C.1    Perry, J.L.2    Pritchard, J.B.3
  • 366
    • 15744362693 scopus 로고    scopus 로고
    • Molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters, hOCT2 and rbOCT2
    • Suhre WM, Ekins S, Chang C, Swaan PW, Wright SH. Molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters, hOCT2 and rbOCT2. Mol Pharmacol 67: 1067-1077, 2005.
    • (2005) Mol Pharmacol , vol.67 , pp. 1067-1077
    • Suhre, W.M.1    Ekins, S.2    Chang, C.3    Swaan, P.W.4    Wright, S.H.5
  • 368
    • 0037178852 scopus 로고    scopus 로고
    • Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 [Slc22a8]) knockout mice
    • Sweet DH, Miller DS, Pritchard JB, Fujiwara Y, Beier DR, Nigam SK. Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 [Slc22a8]) knockout mice. J Biol Chem 277: 26934-26943, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 26934-26943
    • Sweet, D.H.1    Miller, D.S.2    Pritchard, J.B.3    Fujiwara, Y.4    Beier, D.R.5    Nigam, S.K.6
  • 369
    • 0030781076 scopus 로고    scopus 로고
    • Expression cloning and characterization of ROAT1: The renal basolateral organic anion transporter in rat kidney
    • Sweet DH, Wolff NA, Pritchard JB. Expression cloning and characterization of ROAT1: The renal basolateral organic anion transporter in rat kidney. J Biol Chem 272: 30088-30095, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 30088-30095
    • Sweet, D.H.1    Wolff, N.A.2    Pritchard, J.B.3
  • 370
    • 76949139107 scopus 로고
    • Protein binding of p-aminohippurate in human and dog plasma
    • Taggart JV. Protein binding of p-aminohippurate in human and dog plasma. Am J Physiol 167, 248-254, 1951.
    • (1951) Am J Physiol , vol.167 , pp. 248-254
    • Taggart, J.V.1
  • 371
    • 44949087480 scopus 로고    scopus 로고
    • Polymorphism in human organic cation transporters and metformin action
    • Takane H, Shikata E, Otsubo K, Higuchi S, Ieiri I. Polymorphism in human organic cation transporters and metformin action. Pharmacogenomics 9: 415-422, 2008.
    • (2008) Pharmacogenomics , vol.9 , pp. 415-422
    • Takane, H.1    Shikata, E.2    Otsubo, K.3    Higuchi, S.4    Ieiri, I.5
  • 372
    • 0021255131 scopus 로고
    • Carrier-mediated transport systems of tetraethylammonium in rat renal brush-border and basolateral membrane vesicles
    • Takano M, Inui K-I, Okano T, Saito H, Hori R. Carrier-mediated transport systems of tetraethylammonium in rat renal brush-border and basolateral membrane vesicles. Biochim Biophys Acta 773: 113-124, 1984.
    • (1984) Biochim Biophys Acta , vol.773 , pp. 113-124
    • Takano, M.1    Inui, K.-I.2    Okano, T.3    Saito, H.4    Hori, R.5
  • 374
    • 0034698403 scopus 로고    scopus 로고
    • Regulation by protein kinase C of organic anion transport driven by rat organic anion transporter 3 (rOAT3)
    • Takeda M, Sekine T, Endou H. Regulation by protein kinase C of organic anion transport driven by rat organic anion transporter 3 (rOAT3). Life Sci 67: 1087-1093, 2000.
    • (2000) Life Sci , vol.67 , pp. 1087-1093
    • Takeda, M.1    Sekine, T.2    Endou, H.3
  • 376
    • 0032493741 scopus 로고    scopus 로고
    • Molecular and functional identification of sodium iondependent, high affinity human carnitine transporter OCTN2
    • Tamai I, Ohashi R, Nezu J, Yabuuchi H, Oku A, Shimane M, Sai Y, Tsuji A. Molecular and functional identification of sodium iondependent, high affinity human carnitine transporter OCTN2. J Biol Chem 273: 20378-20382, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 20378-20382
    • Tamai, I.1    Ohashi, R.2    Nezu, J.3    Yabuuchi, H.4    Oku, A.5    Shimane, M.6    Sai, Y.7    Tsuji, A.8
  • 377
    • 0031434178 scopus 로고    scopus 로고
    • Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1
    • Tamai I, Yabuuchi H, Nezu J-I, Sai Y, Oku A, Shimane M, Tsuji A. Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1. FEBS Lett 419: 107-111, 1997.
    • (1997) FEBS Lett , vol.419 , pp. 107-111
    • Tamai, I.1    Yabuuchi, H.2    Nezu, J.-I.3    Sai, Y.4    Oku, A.5    Shimane, M.6    Tsuji, A.7
  • 378
    • 2442479788 scopus 로고    scopus 로고
    • Role of glycosylation in the organic anion transporter OAT1
    • Tanaka K, Xu W, Zhou F, You G. Role of glycosylation in the organic anion transporter OAT1. J Biol Chem 279: 14961-14966, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 14961-14966
    • Tanaka, K.1    Xu, W.2    Zhou, F.3    You, G.4
  • 379
    • 2642564429 scopus 로고    scopus 로고
    • Cysteine residues in the organic anion transporter mOAT1
    • Tanaka K, Zhou F, Kuze K, You G. Cysteine residues in the organic anion transporter mOAT1. Biochem J 380: 283-287, 2004.
    • (2004) Biochem J , vol.380 , pp. 283-287
    • Tanaka, K.1    Zhou, F.2    Kuze, K.3    You, G.4
  • 380
    • 0032997735 scopus 로고    scopus 로고
    • Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency
    • Tang NL, Ganapathy V, Wu X, Hui J, Seth P, Yuen PM, Wanders RJ, Fok TF, Hjelm NM. Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency. Hum Mol Genet 8: 655-660, 1999.
    • (1999) Hum Mol Genet , vol.8 , pp. 655-660
    • Tang, N.L.1    Ganapathy, V.2    Wu, X.3    Hui, J.4    Seth, P.5    Yuen, P.M.6    Wanders, R.J.7    Fok, T.F.8    Hjelm, N.M.9
  • 381
    • 40349096090 scopus 로고    scopus 로고
    • Control of renal uric acid excretion and gout
    • Taniguchi A, Kamatani N. Control of renal uric acid excretion and gout. Curr Opin Rheumatol 20: 192-197, 2008.
    • (2008) Curr Opin Rheumatol , vol.20 , pp. 192-197
    • Taniguchi, A.1    Kamatani, N.2
  • 382
    • 23644434855 scopus 로고    scopus 로고
    • A common mutation in an organic anion transporter gene, SLC22A12, is a suppressing factor for the development of gout
    • Taniguchi A, Urano W, Yamanaka M, Yamanaka H, Hosoyamada M, Endou H, Kamatani N. A common mutation in an organic anion transporter gene, SLC22A12, is a suppressing factor for the development of gout. Arthritis Rheum 52: 2576-2577, 2005.
    • (2005) Arthritis Rheum , vol.52 , pp. 2576-2577
    • Taniguchi, A.1    Urano, W.2    Yamanaka, M.3    Yamanaka, H.4    Hosoyamada, M.5    Endou, H.6    Kamatani, N.7
  • 383
    • 9544233652 scopus 로고    scopus 로고
    • A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation
    • Taniguchi K, Wada M, Kohno K, Nakamura T, Kawabe T, Kawakami M, Kagotani K, Okumura K, Akiyama S, Kuwano M. A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation. Cancer Res 56: 4124-4129, 1996.
    • (1996) Cancer Res , vol.56 , pp. 4124-4129
    • Taniguchi, K.1    Wada, M.2    Kohno, K.3    Nakamura, T.4    Kawabe, T.5    Kawakami, M.6    Kagotani, K.7    Okumura, K.8    Akiyama, S.9    Kuwano, M.10
  • 384
    • 70249087629 scopus 로고    scopus 로고
    • Protective effect of concomitant administration of imatinib on cisplatin-induced nephrotoxicity focusing on renal organic cation transporter OCT2
    • Tanihara Y, Masuda S, Katsura T, Inui K. Protective effect of concomitant administration of imatinib on cisplatin-induced nephrotoxicity focusing on renal organic cation transporter OCT2. Biochem Pharmacol 78: 1263-1271, 2009.
    • (2009) Biochem Pharmacol , vol.78 , pp. 1263-1271
    • Tanihara, Y.1    Masuda, S.2    Katsura, T.3    Inui, K.4
  • 386
    • 0038042481 scopus 로고    scopus 로고
    • Carnitine transport: Pathophysiology and metabolism of known molecular defects
    • Tein I. Carnitine transport: Pathophysiology and metabolism of known molecular defects. J Inherit Metab Dis 26: 147-169, 2003.
    • (2003) J Inherit Metab Dis , vol.26 , pp. 147-169
    • Tein, I.1
  • 387
    • 41949113401 scopus 로고    scopus 로고
    • +/organic cation antiporters (MATE/SLC47A)
    • +/organic cation antiporters (MATE/SLC47A). Biochem Pharmacol 75: 1689-1696, 2008.
    • (2008) Biochem Pharmacol , vol.75 , pp. 1689-1696
    • Terada, T.1    Inui, K.2
  • 388
    • 33746508758 scopus 로고    scopus 로고
    • Molecular cloning, functional characterization and tissue distribution of rat H(+)/organic cation antiporter MATE1
    • Terada T, Masuda S, Asaka JI, Tsuda M, Katsura T, Inui KI. Molecular cloning, functional characterization and tissue distribution of rat H(+)/organic cation antiporter MATE1. Pharm Res 23: 1696-1701, 2006.
    • (2006) Pharm Res , vol.23 , pp. 1696-1701
    • Terada, T.1    Masuda, S.2    Asaka, J.I.3    Tsuda, M.4    Katsura, T.5    Inui, K.I.6
  • 390
    • 0034990906 scopus 로고    scopus 로고
    • Nephrotoxicants induce endothelin release and signaling in renal proximal tubules: Effect on drug efflux
    • Terlouw SA, Masereeuw R, Russel FG, Miller DS. Nephrotoxicants induce endothelin release and signaling in renal proximal tubules: Effect on drug efflux. Mol Pharmacol 59: 1433-1440, 2001.
    • (2001) Mol Pharmacol , vol.59 , pp. 1433-1440
    • Terlouw, S.A.1    Masereeuw, R.2    Russel, F.G.3    Miller, D.S.4
  • 391
    • 0035165303 scopus 로고    scopus 로고
    • Role of multidrug resistance protein 2 (MRP2) in glutathionebimane efflux from Caco-2 and rat renal proximal tubule cells
    • Terlouw SA, Masereeuw R, Van Den Broek PH, Notenboom S, Russel FG. Role of multidrug resistance protein 2 (MRP2) in glutathionebimane efflux from Caco-2 and rat renal proximal tubule cells. Br J Pharmacol 134: 931-938, 2001.
    • (2001) Br J Pharmacol , vol.134 , pp. 931-938
    • Terlouw, S.A.1    Masereeuw, R.2    Van Den Broek, P.H.3    Notenboom, S.4    Russel, F.G.5
  • 393
    • 0023447098 scopus 로고
    • Cellular localization of multidrug resistance gene product P-glycoprotein in normal human tissues
    • Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I. Cellular localization of multidrug resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci U S A 84: 7735-7738, 1987.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 7735-7738
    • Thiebaut, F.1    Tsuruo, T.2    Hamada, H.3    Gottesman, M.M.4    Pastan, I.5
  • 395
    • 0033361943 scopus 로고    scopus 로고
    • Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) andmutations in the ATP-binding-cassette region in Dubin-Johnson syndrome
    • Toh S, Wada M, Uchiumi T, Inokuchi A, Makino Y, Horie Y, Adachi Y, Sakisaka S, Kuwano M. Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) andmutations in the ATP-binding-cassette region in Dubin-Johnson syndrome. Am J Hum Genet 64: 739-746, 1999.
    • (1999) Am J Hum Genet , vol.64 , pp. 739-746
    • Toh, S.1    Wada, M.2    Uchiumi, T.3    Inokuchi, A.4    Makino, Y.5    Horie, Y.6    Adachi, Y.7    Sakisaka, S.8    Kuwano, M.9
  • 397
    • 66849142125 scopus 로고    scopus 로고
    • Targeted disruption of the multidrug and toxin extrusion 1 (Mate1) gene in mice reduces renal secretion of metformin
    • Tsuda M, Terada T, Mizuno T, Katsura T, Shimakura J, Inui KI. Targeted disruption of the multidrug and toxin extrusion 1 (Mate1) gene in mice reduces renal secretion of metformin. Mol Pharmacol 75: 1280-1286, 2009.
    • (2009) Mol Pharmacol , vol.75 , pp. 1280-1286
    • Tsuda, M.1    Terada, T.2    Mizuno, T.3    Katsura, T.4    Shimakura, J.5    Inui, K.I.6
  • 398
    • 63849121023 scopus 로고    scopus 로고
    • Involvement of human multidrug and toxin extrusion 1 in the drug interaction between cimetidine and metformin in renal epithelial cells
    • Tsuda M, Terada T, Ueba M, Sato T, Masuda S, Katsura T, Inui K. Involvement of human multidrug and toxin extrusion 1 in the drug interaction between cimetidine and metformin in renal epithelial cells. J Pharmacol Exp Ther 329: 185-191, 2009.
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 185-191
    • Tsuda, M.1    Terada, T.2    Ueba, M.3    Sato, T.4    Masuda, S.5    Katsura, T.6    Inui, K.7
  • 399
    • 0032842748 scopus 로고    scopus 로고
    • Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin-Johnson syndrome
    • Tsujii H, König J, Rost D, Stockel B, Leuschner U, Keppler D. Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin-Johnson syndrome. Gastroenterology 117: 653-660, 1999.
    • (1999) Gastroenterology , vol.117 , pp. 653-660
    • Tsujii, H.1    König, J.2    Rost, D.3    Stockel, B.4    Leuschner, U.5    Keppler, D.6
  • 402
    • 0030850803 scopus 로고    scopus 로고
    • Renal transporters for organic anions and cations. Structural requirements for substrates
    • Ullrich KJ. Renal transporters for organic anions and cations. Structural requirements for substrates. J Membrane Biol 158: 95-107, 1997.
    • (1997) J Membrane Biol , vol.158 , pp. 95-107
    • Ullrich, K.J.1
  • 403
    • 0028276773 scopus 로고
    • Polysubstrates: Substances that interact with renal contraluminal PAH, sulfate, and NMeN transport: Sulfamoyl-, sulfonylurea-, thiazide- and benzeneaminocarboxylate (nicotinate) compounds
    • Ullrich KJ, Fritzsch G, Rumrich G, David C. Polysubstrates: Substances that interact with renal contraluminal PAH, sulfate, and NMeN transport: Sulfamoyl-, sulfonylurea-, thiazide- and benzeneaminocarboxylate (nicotinate) compounds. J Pharmacol Exp Ther 269: 684-692, 1994.
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 684-692
    • Ullrich, K.J.1    Fritzsch, G.2    Rumrich, G.3    David, C.4
  • 405
    • 0028998330 scopus 로고
    • +/organic cation exchanger, and luminal choline transporter
    • +/organic cation exchanger, and luminal choline transporter. Cell Physiol Biochem 5: 290-298, 1995.
    • (1995) Cell Physiol Biochem , vol.5 , pp. 290-298
    • Ullrich, K.J.1    Rumrich, G.2
  • 406
    • 0030037094 scopus 로고    scopus 로고
    • 4-groups, methylaminostyryl, rhodamine, acridine, phenanthrene and cyanine compounds
    • 4-groups, methylaminostyryl, rhodamine, acridine, phenanthrene and cyanine compounds. Pflügers Arch 432: 471-485, 1996.
    • (1996) Pflügers Arch , vol.432 , pp. 471-485
    • Ullrich, K.J.1    Rumrich, G.2
  • 407
    • 0027373329 scopus 로고
    • Bisubstrates: Substances that interact with both, renal contraluminal organic anion and organic cation transport systems. II. Zwitterionic substrates: Dipeptides, cephalosporins, quinolone-carboxylate gyrase inhibitors and phosphoamide thiazine carboxylates; nonionizable substrates: Steroid hormones and cyclophosphamides
    • Ullrich KJ, Rumrich G, David C, Fritzsch G. Bisubstrates: Substances that interact with both, renal contraluminal organic anion and organic cation transport systems. II. Zwitterionic substrates: Dipeptides, cephalosporins, quinolone-carboxylate gyrase inhibitors and phosphoamide thiazine carboxylates; nonionizable substrates: Steroid hormones and cyclophosphamides. Pflugers Arch 425: 300-312, 1993a.
    • (1993) Pflugers Arch , vol.425 , pp. 300-312
    • Ullrich, K.J.1    Rumrich, G.2    David, C.3    Fritzsch, G.4
  • 408
    • 0027378438 scopus 로고
    • Bisubstrates: Substances that interact with renal organic anion and organic cation transport systems. I. Amines, piperidines, piperazines, azepines, pyridines, quinolines, imadazoles, thiazoles, guanidines, and hydrazines
    • Ullrich KJ, Rumrich G, David C, Fritzsch G. Bisubstrates: Substances that interact with renal organic anion and organic cation transport systems. I. Amines, piperidines, piperazines, azepines, pyridines, quinolines, imadazoles, thiazoles, guanidines, and hydrazines. Pflugers Arch 425: 280-299, 1993b.
    • (1993) Pflugers Arch , vol.425 , pp. 280-299
    • Ullrich, K.J.1    Rumrich, G.2    David, C.3    Fritzsch, G.4
  • 409
    • 0026565716 scopus 로고
    • Contraluminal transport of organic cations in the proximal tubule of the rat kidney. II. Specificity: Anilines, phenylalkylamines (catecholamines), heterocyclic compounds (pyridines, quinolines, acridines)
    • Ullrich KJ, Rumrich G, Fritzsch G. Contraluminal transport of organic cations in the proximal tubule of the rat kidney. II. Specificity: Anilines, phenylalkylamines (catecholamines), heterocyclic compounds (pyridines, quinolines, acridines). Pflugers Arch 420: 29-38, 1992.
    • (1992) Pflugers Arch , vol.420 , pp. 29-38
    • Ullrich, K.J.1    Rumrich, G.2    Fritzsch, G.3
  • 410
    • 0036294807 scopus 로고    scopus 로고
    • cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 Predominantly Expressed in the Human Kidney
    • Urakami Y, Akazawa M, Saito H, Okuda M, Inui K. cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 Predominantly Expressed in the Human Kidney. J Am Soc Nephrol 13: 1703-1710, 2002.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1703-1710
    • Urakami, Y.1    Akazawa, M.2    Saito, H.3    Okuda, M.4    Inui, K.5
  • 412
    • 0034640217 scopus 로고    scopus 로고
    • Hormonal regulation of organic cation transporter OCT2 expression in rat kidney
    • Urakami Y, Okuda M, Saito H, Inui K. Hormonal regulation of organic cation transporter OCT2 expression in rat kidney. FEBS Lett 473: 173-176, 2000.
    • (2000) FEBS Lett , vol.473 , pp. 173-176
    • Urakami, Y.1    Okuda, M.2    Saito, H.3    Inui, K.4
  • 414
    • 0032836646 scopus 로고    scopus 로고
    • Mechanisms and interaction of vinblastine and reduced glutathione transport in membrane vesicles by the rabbit multidrug resistance protein MRP2 expressed in insect cells
    • van Aubel RA, Koenderink JB, Peters JG, van Os CH, Russel FG. Mechanisms and interaction of vinblastine and reduced glutathione transport in membrane vesicles by the rabbit multidrug resistance protein MRP2 expressed in insect cells. Mol Pharmacol 56: 714-719, 1999.
    • (1999) Mol Pharmacol , vol.56 , pp. 714-719
    • van Aubel, R.A.1    Koenderink, J.B.2    Peters, J.G.3    van Os, C.H.4    Russel, F.G.5
  • 415
    • 0033713976 scopus 로고    scopus 로고
    • Multidrug resistance protein MRP2 mediates ATP-dependent transport of classic renal organic anion p-aminohippurate
    • van Aubel RA, Peters JG, Masereeuw R, van Os CH, Russel FG. Multidrug resistance protein MRP2 mediates ATP-dependent transport of classic renal organic anion p-aminohippurate. Am J Physiol Renal Physiol 279: F713-F717, 2000.
    • (2000) Am J Physiol Renal Physiol , vol.279
    • van Aubel, R.A.1    Peters, J.G.2    Masereeuw, R.3    van Os, C.H.4    Russel, F.G.5
  • 416
    • 0036186107 scopus 로고    scopus 로고
    • The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: Putative efflux pump for urinary cAMP and cGMP
    • van Aubel RA, Smeets PH, Peters JG, Bindels RJ, Russel FG. The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: Putative efflux pump for urinary cAMP and cGMP. J Am Soc Nephrol 13: 595-603, 2002.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 595-603
    • van Aubel, R.A.1    Smeets, P.H.2    Peters, J.G.3    Bindels, R.J.4    Russel, F.G.5
  • 417
    • 12144257103 scopus 로고    scopus 로고
    • Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites
    • van Aubel RA, Smeets PH, Van Den Heuvel JJ, Russel FG. Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites. Am J Physiol Renal Physiol 288: F327-F333, 2005.
    • (2005) Am J Physiol Renal Physiol , vol.288
    • van Aubel, R.A.1    Smeets, P.H.2    Van Den Heuvel, J.J.3    Russel, F.G.4
  • 418
    • 0031841605 scopus 로고    scopus 로고
    • Adenosine triphosphate-dependent transport of anionic conjugates by the rabbitmultidrug resistance-associated protein MRP2 expressed in insect cells
    • van Aubel RAMH, van Kuijck MA, Koenderink JB, Deen PMT, van Os CH, Russel FGM. Adenosine triphosphate-dependent transport of anionic conjugates by the rabbitmultidrug resistance-associated protein MRP2 expressed in insect cells. Mol Pharm 53: 1062-1067, 1998.
    • (1998) Mol Pharm , vol.53 , pp. 1062-1067
    • van Aubel, R.A.M.H.1    van Kuijck, M.A.2    Koenderink, J.B.3    Deen, P.M.T.4    van Os, C.H.5    Russel, F.G.M.6
  • 419
    • 26444539011 scopus 로고    scopus 로고
    • Function and regulation of multidrug resistance proteins (MRPs) in the renal elimination of organic anions
    • van de Water FM, Masereeuw R, Russel FG. Function and regulation of multidrug resistance proteins (MRPs) in the renal elimination of organic anions. Drug Metab Rev 37: 443-471, 2005.
    • (2005) Drug Metab Rev , vol.37 , pp. 443-471
    • van de Water, F.M.1    Masereeuw, R.2    Russel, F.G.3
  • 420
    • 0034968246 scopus 로고    scopus 로고
    • Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides
    • van Montfoort JE, Muller M, Groothuis GM, Meijer DK, Koepsell H, Meier PJ. Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides. J Pharmacol Exp Ther 298: 110-115, 2001.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 110-115
    • van Montfoort, J.E.1    Muller, M.2    Groothuis, G.M.3    Meijer, D.K.4    Koepsell, H.5    Meier, P.J.6
  • 421
    • 75349105185 scopus 로고    scopus 로고
    • Organic anion transporters: Discovery, pharmacology, regulation and roles in pathophysiology
    • Vanwert AL, Gionfriddo MR, Sweet DH. Organic anion transporters: Discovery, pharmacology, regulation and roles in pathophysiology. Biopharm Drug Dispos 31: 1-71, 2010.
    • (2010) Biopharm Drug Dispos , vol.31 , pp. 1-71
    • Vanwert, A.L.1    Gionfriddo, M.R.2    Sweet, D.H.3
  • 422
    • 3042665547 scopus 로고    scopus 로고
    • Structural conservation in the major facilitator superfamily as revealed by comparative modeling
    • Vardy E, Arkin IT, Gottschalk KE, Kaback HR, Schuldiner S. Structural conservation in the major facilitator superfamily as revealed by comparative modeling. Protein Sci 13: 1832-1840, 2004.
    • (2004) Protein Sci , vol.13 , pp. 1832-1840
    • Vardy, E.1    Arkin, I.T.2    Gottschalk, K.E.3    Kaback, H.R.4    Schuldiner, S.5
  • 424
    • 0142179119 scopus 로고    scopus 로고
    • Different affinities of inhibitors to the outwardly and inwardly directed substrate binding site of organic cation transporter 2
    • Volk C, Gorboulev V, Budiman T, Nagel G, Koepsell H. Different affinities of inhibitors to the outwardly and inwardly directed substrate binding site of organic cation transporter 2. Mol Pharmacol 64: 1037-1047, 2003.
    • (2003) Mol Pharmacol , vol.64 , pp. 1037-1047
    • Volk, C.1    Gorboulev, V.2    Budiman, T.3    Nagel, G.4    Koepsell, H.5
  • 426
    • 0033515017 scopus 로고    scopus 로고
    • Mutations in the organic cation/carnitine transporter OCTN2 in primary carnitine deficiency
    • Wang Y, Ye J, Ganapathy V, Longo N. Mutations in the organic cation/carnitine transporter OCTN2 in primary carnitine deficiency. Proc Natl Acad Sci U S A 96: 2356-2360, 1999.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 2356-2360
    • Wang, Y.1    Ye, J.2    Ganapathy, V.3    Longo, N.4
  • 427
    • 53049095113 scopus 로고    scopus 로고
    • OCT2 polymorphisms and in-vivo renal functional consequence: Studies with metformin and cimetidine
    • Wang ZJ, Yin OQ, Tomlinson B, Chow MS. OCT2 polymorphisms and in-vivo renal functional consequence: Studies with metformin and cimetidine. Pharmacogenet Genomics 18: 637-645, 2008.
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 637-645
    • Wang, Z.J.1    Yin, O.Q.2    Tomlinson, B.3    Chow, M.S.4
  • 428
    • 77954905149 scopus 로고    scopus 로고
    • Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice
    • Watanabe S, Tsuda M, Terada T, Katsura T, Inui KI. Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice. J Pharmacol Exp Ther 334: 651-656, 2010.
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 651-656
    • Watanabe, S.1    Tsuda, M.2    Terada, T.3    Katsura, T.4    Inui, K.I.5
  • 429
    • 3242838372 scopus 로고
    • Urate transport in the nephron
    • Weiner IM. Urate transport in the nephron. Am J Physiol 237: F85-F92, 1979.
    • (1979) Am J Physiol , vol.237
    • Weiner, I.M.1
  • 430
    • 0031936232 scopus 로고    scopus 로고
    • Effect of aketoglutarate on organic anion transport in single rabbit renal proximal tubules
    • Welborn JR, Shpun S, Dantzler WH, Wright SH. Effect of aketoglutarate on organic anion transport in single rabbit renal proximal tubules. Am J Physiol 274: F165-F174, 1998.
    • (1998) Am J Physiol , vol.274
    • Welborn, J.R.1    Shpun, S.2    Dantzler, W.H.3    Wright, S.H.4
  • 431
    • 18244399574 scopus 로고    scopus 로고
    • Role of the NH2-terminalmembrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and trafficking
    • Westlake CJ, Cole SP, Deeley RG. Role of the NH2-terminalmembrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and trafficking. Mol Biol Cell 16: 2483-2492, 2005.
    • (2005) Mol Biol Cell , vol.16 , pp. 2483-2492
    • Westlake, C.J.1    Cole, S.P.2    Deeley, R.G.3
  • 432
    • 0344629891 scopus 로고    scopus 로고
    • Identification of the structural and functional boundaries of the multidrug resistance protein 1 cytoplasmic loop 3
    • Westlake CJ, Qian YM, Gao M, Vasa M, Cole SP, Deeley RG. Identification of the structural and functional boundaries of the multidrug resistance protein 1 cytoplasmic loop 3. Biochemistry 42: 14099-14113, 2003.
    • (2003) Biochemistry , vol.42 , pp. 14099-14113
    • Westlake, C.J.1    Qian, Y.M.2    Gao, M.3    Vasa, M.4    Cole, S.P.5    Deeley, R.G.6
  • 433
    • 33846260243 scopus 로고    scopus 로고
    • Endothelin and calciotropic hormones share regulatory pathways in multidrug resistance protein 2-mediated transport
    • Wever KE, Masereeuw R, Miller DS, Hang XM, Flik G. Endothelin and calciotropic hormones share regulatory pathways in multidrug resistance protein 2-mediated transport. Am J Physiol Renal Physiol 292: F38-F46, 2007.
    • (2007) Am J Physiol Renal Physiol , vol.292
    • Wever, K.E.1    Masereeuw, R.2    Miller, D.S.3    Hang, X.M.4    Flik, G.5
  • 434
    • 0037705377 scopus 로고    scopus 로고
    • Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells
    • Wielinga PR, van der Heijden I, Reid G, Beijnen JH, Wijnholds J, Borst P. Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells. J Biol Chem278: 17664-17671, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 17664-17671
    • Wielinga, P.R.1    van der Heijden, I.2    Reid, G.3    Beijnen, J.H.4    Wijnholds, J.5    Borst, P.6
  • 436
    • 0034823731 scopus 로고    scopus 로고
    • Cationic amino acids involved in dicarboxylate binding of the flounder renal organic anion transporter
    • Wolff NA, Grunwald B, Friedrich B, Lang F, Godehardt S, Burckhardt G. Cationic amino acids involved in dicarboxylate binding of the flounder renal organic anion transporter. J Am Soc Nephrol 12: 2012-2018, 2001.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 2012-2018
    • Wolff, N.A.1    Grunwald, B.2    Friedrich, B.3    Lang, F.4    Godehardt, S.5    Burckhardt, G.6
  • 437
    • 0042844712 scopus 로고    scopus 로고
    • Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization
    • WolffNA, Thies K, Kuhnke N, Reid G, Friedrich B, Lang F, Burckhardt G. Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization. J Am Soc Nephrol 14: 1959-1968, 2003.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1959-1968
    • Wolff, N.A.1    Thies, K.2    Kuhnke, N.3    Reid, G.4    Friedrich, B.5    Lang, F.6    Burckhardt, G.7
  • 439
    • 0022335603 scopus 로고
    • 1-methylnicotinamide across brush border membrane vesicles from rabbit kidney
    • Wright SH. Transport of N1-methylnicotinamide across brush border membrane vesicles from rabbit kidney. Am J Physiol 249: F903-F911, 1985.
    • (1985) Am J Physiol , vol.249
    • Wright, S.H.1
  • 440
    • 3042542425 scopus 로고    scopus 로고
    • Molecular and cellular physiology of renal organic cation and anion transport
    • Wright SH, Dantzler WH. Molecular and cellular physiology of renal organic cation and anion transport. Physiol Rev 84: 987-1049, 2004.
    • (2004) Physiol Rev , vol.84 , pp. 987-1049
    • Wright, S.H.1    Dantzler, W.H.2
  • 442
    • 0023499741 scopus 로고
    • Transport of tetraethylammonium by rabbit renal brush-border and basolateral membrane vesicles
    • Wright SH, Wunz TM. Transport of tetraethylammonium by rabbit renal brush-border and basolateral membrane vesicles. Am J Physiol 253: F1040-F1050, 1987.
    • (1987) Am J Physiol , vol.253
    • Wright, S.H.1    Wunz, T.M.2
  • 443
    • 0031821705 scopus 로고    scopus 로고
    • + exchanger of the renal luminal membrane
    • + exchanger of the renal luminal membrane. Pflügers Arch 436: 469-477, 1998.
    • (1998) Pflügers Arch , vol.436 , pp. 469-477
    • Wright, S.H.1    Wunz, T.M.2
  • 445
    • 0026537736 scopus 로고
    • A choline transporter in renal brush-border membrane vesicles: Energetics and structural specificity
    • Wright SH, Wunz TM, Wunz TP. A choline transporter in renal brush-border membrane vesicles: Energetics and structural specificity. J Membr Biol 126: 51-65, 1992.
    • (1992) J Membr Biol , vol.126 , pp. 51-65
    • Wright, S.H.1    Wunz, T.M.2    Wunz, T.P.3
  • 446
  • 447
    • 0034212998 scopus 로고    scopus 로고
    • Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta
    • Wu X, George RL, Huang W, Wang H, Conway SJ, Leibach FH, Ganapathy V. Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta. Biochim Biophys Acta 1466: 315-327, 2000.
    • (2000) Biochim Biophys Acta , vol.1466 , pp. 315-327
    • Wu, X.1    George, R.L.2    Huang, W.3    Wang, H.4    Conway, S.J.5    Leibach, F.H.6    Ganapathy, V.7
  • 449
    • 0032577202 scopus 로고    scopus 로고
    • cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family
    • Wu X, Prasad PD, Leibach FH, Ganapathy V. cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family. Biochem Biophys Res Commun 246: 589-595, 1998.
    • (1998) Biochem Biophys Res Commun , vol.246 , pp. 589-595
    • Wu, X.1    Prasad, P.D.2    Leibach, F.H.3    Ganapathy, V.4
  • 450
    • 0026592267 scopus 로고
    • Two independent mutational events in the loss of urate oxidase during hominoid evolution
    • Wu XW, Muzny DM, Lee CC, Caskey CT. Two independent mutational events in the loss of urate oxidase during hominoid evolution. J Mol Evol 34: 78-84, 1992.
    • (1992) J Mol Evol , vol.34 , pp. 78-84
    • Wu, X.W.1    Muzny, D.M.2    Lee, C.C.3    Caskey, C.T.4
  • 451
    • 33845983672 scopus 로고    scopus 로고
    • Functional role of the C terminus of human organic anion transporter hOAT1
    • Xu W, Tanaka K, Sun AQ, You G. Functional role of the C terminus of human organic anion transporter hOAT1. J Biol Chem 281: 31178-31183, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 31178-31183
    • Xu, W.1    Tanaka, K.2    Sun, A.Q.3    You, G.4
  • 452
    • 64549087547 scopus 로고    scopus 로고
    • Molecular and functional characterization of choline transporter in rat renal tubule epithelial NRK-52E cells
    • Yabuki M, Inazu M, Yamada T, Tajima H, Matsumiya T. Molecular and functional characterization of choline transporter in rat renal tubule epithelial NRK-52E cells. Arch Biochem Biophys 485: 88-96, 2009.
    • (2009) Arch Biochem Biophys , vol.485 , pp. 88-96
    • Yabuki, M.1    Inazu, M.2    Yamada, T.3    Tajima, H.4    Matsumiya, T.5
  • 453
    • 0032935034 scopus 로고    scopus 로고
    • Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations
    • Yabuuchi H, Tamai I, Nezu JI, Sakamoto K, Oku A, ShimaneM, Sai Y, Tsuji A. Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations. J Pharmacol Exp Ther 289: 768-773, 1999.
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 768-773
    • Yabuuchi, H.1    Tamai, I.2    Nezu, J.I.3    Sakamoto, K.4    Oku, A.5    Shimane, M.6    Sai, Y.7    Tsuji, A.8
  • 454
    • 77956921025 scopus 로고    scopus 로고
    • Characterization of cellular uptake of perfluorooctanoate via organic anion-transporting polypeptide 1A2, organic anion transporter 4, and urate transporter 1 for their potential roles in mediating human renal reabsorption of perfluorocarboxylates
    • Yang CH, Glover KP, Han X. Characterization of cellular uptake of perfluorooctanoate via organic anion-transporting polypeptide 1A2, organic anion transporter 4, and urate transporter 1 for their potential roles in mediating human renal reabsorption of perfluorocarboxylates. Toxicol Sci 117: 294-302, 2010.
    • (2010) Toxicol Sci , vol.117 , pp. 294-302
    • Yang, C.H.1    Glover, K.P.2    Han, X.3
  • 455
    • 34250764918 scopus 로고    scopus 로고
    • Differential contribution of organic cation transporters, OCT2 andMATE1, in platinum agent-induced nephrotoxicity
    • Yokoo S, Yonezawa A, Masuda S, Fukatsu A, Katsura T, Inui K. Differential contribution of organic cation transporters, OCT2 andMATE1, in platinum agent-induced nephrotoxicity. Biochem Pharmacol 74: 477-487, 2007.
    • (2007) Biochem Pharmacol , vol.74 , pp. 477-487
    • Yokoo, S.1    Yonezawa, A.2    Masuda, S.3    Fukatsu, A.4    Katsura, T.5    Inui, K.6
  • 456
    • 0021686364 scopus 로고
    • Cell pH of rat renal proximal tubule in vivo and the conductive nature of peritubular HCO3- (OH-) exit
    • -) exit. Pflugers Arch 402: 300-305, 1984.
    • (1984) Pflugers Arch , vol.402 , pp. 300-305
    • Yoshitomi, K.1    Frömter, E.2
  • 457
    • 0034616345 scopus 로고    scopus 로고
    • Regulation of mOAT-mediated organic anion transport by okadaic acid and protein kinase C in LLC-PK(1) cells
    • You G, Kuze K, Kohanski RA, Amsler K, Henderson S. Regulation of mOAT-mediated organic anion transport by okadaic acid and protein kinase C in LLC-PK(1) cells. J Biol Chem 275: 10278-10284, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 10278-10284
    • You, G.1    Kuze, K.2    Kohanski, R.A.3    Amsler, K.4    Henderson, S.5
  • 458
    • 33745646959 scopus 로고    scopus 로고
    • Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1
    • Yuan Z, Tie A, Tarnopolsky M, Bakovic M. Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1. Physiol Genomics 26: 76-90, 2006.
    • (2006) Physiol Genomics , vol.26 , pp. 76-90
    • Yuan, Z.1    Tie, A.2    Tarnopolsky, M.3    Bakovic, M.4
  • 461
    • 0037693882 scopus 로고    scopus 로고
    • Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4)
    • Zelcer N, Reid G, Wielinga P, Kuil A, Van Der Heijden I, Schuetz J, Borst P. Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4). Biochem J 371: 361-367, 2003.
    • (2003) Biochem J , vol.371 , pp. 361-367
    • Zelcer, N.1    Reid, G.2    Wielinga, P.3    Kuil, A.4    Van Der Heijden, I.5    Schuetz, J.6    Borst, P.7
  • 462
    • 0030985189 scopus 로고    scopus 로고
    • Cloning and functional characterization of a rat renal organic cation transporter isoform (rOCT1A)
    • Zhang L, Dresser MJ, Chun JK, Babbitt PC, Giacomini KM. Cloning and functional characterization of a rat renal organic cation transporter isoform (rOCT1A). J Biol Chem 272: 16548-16554, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 16548-16554
    • Zhang, L.1    Dresser, M.J.2    Chun, J.K.3    Babbitt, P.C.4    Giacomini, K.M.5
  • 463
    • 0033058525 scopus 로고    scopus 로고
    • The interaction of n-tetraalkylammonium compounds with a human organic cation transporter, hOCT1
    • Zhang L, Gorset W, Dresser MJ, Giacomini KM. The interaction of n-tetraalkylammonium compounds with a human organic cation transporter, hOCT1. J Pharmacol Exp Ther 288: 1192-1198, 1999.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 1192-1198
    • Zhang, L.1    Gorset, W.2    Dresser, M.J.3    Giacomini, K.M.4
  • 464
    • 0034052434 scopus 로고    scopus 로고
    • Interactions of HIV protease inhibitors with a human organic cation transporter in a mammalian expression system
    • Zhang L, Gorset W, Washington CB, Blaschke TF, Kroetz DL, Giacomini KM. Interactions of HIV protease inhibitors with a human organic cation transporter in a mammalian expression system. Drug Metab Dispos 28: 329-334, 2000.
    • (2000) Drug Metab Dispos , vol.28 , pp. 329-334
    • Zhang, L.1    Gorset, W.2    Washington, C.B.3    Blaschke, T.F.4    Kroetz, D.L.5    Giacomini, K.M.6
  • 465
    • 0031846917 scopus 로고    scopus 로고
    • Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa)
    • Zhang L, Schaner ME, Giacomini KM. Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa). J Pharmacol Exp Ther 286: 354-361, 1998.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 354-361
    • Zhang, L.1    Schaner, M.E.2    Giacomini, K.M.3
  • 466
    • 15744399684 scopus 로고    scopus 로고
    • Role of glycosylation in trafficking of MRP2 in sandwich-cultured rat hepatocytes
    • Zhang P, Tian X, Chandra P, Brouwer KL. Role of glycosylation in trafficking of MRP2 in sandwich-cultured rat hepatocytes. Mol Pharmacol 67: 1334-1341, 2005.
    • (2005) Mol Pharmacol , vol.67 , pp. 1334-1341
    • Zhang, P.1    Tian, X.2    Chandra, P.3    Brouwer, K.L.4
  • 467
    • 34548048791 scopus 로고    scopus 로고
    • Molecular Identification and functional characterization of rabbit MATE1 and MATE2-K
    • Zhang X, Cherrington NJ, Wright SH. Molecular Identification and functional characterization of rabbit MATE1 and MATE2-K. Am J Physiol Renal Physiol 293: F360, 2007.
    • (2007) Am J Physiol Renal Physiol , vol.293
    • Zhang, X.1    Cherrington, N.J.2    Wright, S.H.3
  • 469
    • 27144555426 scopus 로고    scopus 로고
    • A conserved glutamate residue in transmembrane helix 10 influences substrate specificity of rabbit OCT2 (SLC22A2)
    • Zhang X, Shirahatti NV, Mahadevan D, Wright SH. A conserved glutamate residue in transmembrane helix 10 influences substrate specificity of rabbit OCT2 (SLC22A2). J Biol Chem 280: 34813-34822, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 34813-34822
    • Zhang, X.1    Shirahatti, N.V.2    Mahadevan, D.3    Wright, S.H.4
  • 470
    • 68049094117 scopus 로고    scopus 로고
    • MATE1 has an external COOH terminus, consistent with a 13-helix topology
    • Zhang X, Wright SH. MATE1 has an external COOH terminus, consistent with a 13-helix topology. Am J Physiol Renal Physiol 297: F263-F271, 2009.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Zhang, X.1    Wright, S.H.2
  • 471
    • 0037302804 scopus 로고    scopus 로고
    • Kidney CYP450 enzymes: Biological actions beyond drug metabolism
    • Zhao X, Imig JD. Kidney CYP450 enzymes: Biological actions beyond drug metabolism. Curr Drug Metab 4: 73-84, 2003.
    • (2003) Curr Drug Metab , vol.4 , pp. 73-84
    • Zhao, X.1    Imig, J.D.2
  • 472
    • 33845446759 scopus 로고    scopus 로고
    • Molecular insights into the structure-function relationship of organic anion transporters OATs
    • Zhou F, You G. Molecular insights into the structure-function relationship of organic anion transporters OATs. Pharm Res 24: 28-36, 2007.
    • (2007) Pharm Res , vol.24 , pp. 28-36
    • Zhou, F.1    You, G.2
  • 473
    • 0025950965 scopus 로고
    • Sulfhydryl groups are essential for organic cation exchange in rabbit renal basolateral membrane vesicles
    • Zimmerman WB, Byun E, McKinney TD, Sokol PP. Sulfhydryl groups are essential for organic cation exchange in rabbit renal basolateral membrane vesicles. J Biol Chem 266: 5459-5463, 1991.
    • (1991) J Biol Chem , vol.266 , pp. 5459-5463
    • Zimmerman, W.B.1    Byun, E.2    McKinney, T.D.3    Sokol, P.P.4
  • 475
    • 70450149001 scopus 로고    scopus 로고
    • Current understanding of the pharmacogenomics of metformin
    • Zolk O. Current understanding of the pharmacogenomics of metformin. Clin Pharmacol Ther 86: 595-598, 2009.
    • (2009) Clin Pharmacol Ther , vol.86 , pp. 595-598
    • Zolk, O.1
  • 476
    • 60849100204 scopus 로고    scopus 로고
    • Structural determinants of inhibitor interaction with the human organic cation transporter OCT2 (SLC22A2)
    • Zolk O, Solbach TF, Konig J, Fromm MF. Structural determinants of inhibitor interaction with the human organic cation transporter OCT2 (SLC22A2). Naunyn Schmiedebergs Arch Pharmacol 379: 337-348, 2008.
    • (2008) Naunyn Schmiedebergs Arch Pharmacol , vol.379 , pp. 337-348
    • Zolk, O.1    Solbach, T.F.2    Konig, J.3    Fromm, M.F.4
  • 477
    • 66649087135 scopus 로고    scopus 로고
    • Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser
    • Zolk O, Solbach TF, Konig J, Fromm MF. Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser. Drug Metab Dispos 37: 1312-1318, 2009.
    • (2009) Drug Metab Dispos , vol.37 , pp. 1312-1318
    • Zolk, O.1    Solbach, T.F.2    Konig, J.3    Fromm, M.F.4
  • 478
    • 0034975789 scopus 로고    scopus 로고
    • Impaired activity of the extraneuronal monoamine transporter system known as uptake-2 in Orct3/Slc22a3-deficient mice
    • Zwart R, Verhaagh S, Buitelaar M, Popp-Snijders C, Barlow DP. Impaired activity of the extraneuronal monoamine transporter system known as uptake-2 in Orct3/Slc22a3-deficient mice. Mol Cell Biol 21: 4188-4196, 2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 4188-4196
    • Zwart, R.1    Verhaagh, S.2    Buitelaar, M.3    Popp-Snijders, C.4    Barlow, D.P.5


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