Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites

American Journal of Physiology - Renal Physiology

Volumn 288, Issue 2 57-2, 2005, Pages

  Van Aubel, Rémon A M H ^a,b   Smeets, Pascal H E ^a   Van Den Heuvel, Jeroen J M W ^a   Russel, Frans G M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

cGMP; Kidney; Multidrug resistance protein; Positive cooperativity

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLIC AMP; CYCLIC GMP; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 4; ORGANIC ANION TRANSPORTER; PURINE; URATE;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL LEVEL; CELL STRAIN HEK293; CONTROLLED STUDY; LEPIDOPTERA; NONHUMAN; NUCLEIC ACID TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSPORT KINETICS;

EID: 12144257103     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00133.2004     Document Type: Article

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