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Volumn 56, Issue 6, 1999, Pages 1254-1261

Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; ASPARTIC ACID; CARRIER PROTEIN; CHOLINE; CYANINE DYE; GLUTAMIC ACID; NICOTINAMIDE DERIVATIVE; QUININE; TETRYLAMMONIUM;

EID: 0032723798     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.56.6.1254     Document Type: Article
Times cited : (106)

References (31)
  • 4
    • 0028089888 scopus 로고
    • An efficient site-directed mutagenesis method based on PCR
    • Chen B and Przybyla AE (1994) An efficient site-directed mutagenesis method based on PCR. Biotechniques 17:657-659.
    • (1994) Biotechniques , vol.17 , pp. 657-659
    • Chen, B.1    Przybyla, A.E.2
  • 8
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho SN, Hunt HD, Horton RM, Pullen JK and Pease LR (1989) Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 10
    • 0033534625 scopus 로고    scopus 로고
    • Mutational analysis of aspartate residues in the transmembrane regions and cytoplasmic loops of rat vesicular acetylcholine transporter
    • Kim M-H, Lu M, Lim E-J, Chai Y-G and Hersh LB (1999) Mutational analysis of aspartate residues in the transmembrane regions and cytoplasmic loops of rat vesicular acetylcholine transporter. J Biol Chem 274:673-680.
    • (1999) J Biol Chem , vol.274 , pp. 673-680
    • Kim, M.-H.1    Lu, M.2    Lim, E.-J.3    Chai, Y.-G.4    Hersh, L.B.5
  • 11
    • 0026722234 scopus 로고
    • Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding
    • Kitayama S, Shimada S, Xu H, Markham L, Donovan DM and Uhl GR (1992) Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding. Proc Natl Acad Sci USA 89:7782-7785.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7782-7785
    • Kitayama, S.1    Shimada, S.2    Xu, H.3    Markham, L.4    Donovan, D.M.5    Uhl, G.R.6
  • 12
    • 0031893146 scopus 로고    scopus 로고
    • Organic cation transporters in intestine, kidney, liver, and brain
    • Koepsell H (1998) Organic cation transporters in intestine, kidney, liver, and brain. Anna Rev Physiol 60:243-266.
    • (1998) Anna Rev Physiol , vol.60 , pp. 243-266
    • Koepsell, H.1
  • 13
    • 0032942525 scopus 로고    scopus 로고
    • Molecular pharmacology of organic cation transporters in kidney
    • Koepsell H, Gorboulev V and Arndt P (1999) Molecular pharmacology of organic cation transporters in kidney. J Membr Biol 167:103-117.
    • (1999) J Membr Biol , vol.167 , pp. 103-117
    • Koepsell, H.1    Gorboulev, V.2    Arndt, P.3
  • 15
    • 0033609856 scopus 로고    scopus 로고
    • The transmembrane domains of the human multidrug resistance P-glycoprotein are sufficient to mediate drug binding and trafficking to the cell surface
    • Loo TW and Clarke DM (1999) The transmembrane domains of the human multidrug resistance P-glycoprotein are sufficient to mediate drug binding and trafficking to the cell surface. J Biol Chem 274:24759-24765.
    • (1999) J Biol Chem , vol.274 , pp. 24759-24765
    • Loo, T.W.1    Clarke, D.M.2
  • 16
    • 0029009114 scopus 로고
    • Oligopeptide transport by epithelial cells
    • Meredith D and Boyd CAR (1995) Oligopeptide transport by epithelial cells. J Membr Biol 145:1-12.
    • (1995) J Membr Biol , vol.145 , pp. 1-12
    • Meredith, D.1    Boyd, C.A.R.2
  • 17
    • 0028845359 scopus 로고
    • Identification of residues involved in substrate recognition by a vesicular monoamine transporter
    • Merickel A, Rosandich P, Peter D and Edwards RH (1995) Identification of residues involved in substrate recognition by a vesicular monoamine transporter. J Biol Chem 270:25798-25804.
    • (1995) J Biol Chem , vol.270 , pp. 25798-25804
    • Merickel, A.1    Rosandich, P.2    Peter, D.3    Edwards, R.H.4
  • 19
    • 0030753125 scopus 로고    scopus 로고
    • Molecular aspects of hepatobiliary transport
    • Müller M and Jansen PLM (1997) Molecular aspects of hepatobiliary transport. Am J Physiol 272:G1285-G1303.
    • (1997) Am J Physiol , vol.272
    • Müller, M.1    Jansen, P.L.M.2
  • 23
    • 0029786681 scopus 로고    scopus 로고
    • Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney
    • Saito H, Masuda S and Inui K-i (1996) Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney. J Biol Chem 271:20719-20725.
    • (1996) J Biol Chem , vol.271 , pp. 20719-20725
    • Saito, H.1    Masuda, S.2    Inui, K.-I.3
  • 24
    • 0030968854 scopus 로고    scopus 로고
    • Expression of a putative vesicular acetylcholine transporter facilitates quantal transmitter packaging
    • Song H, Ming G, Fon E, Bellocchio E, Edwards RH and Poo M (1997) Expression of a putative vesicular acetylcholine transporter facilitates quantal transmitter packaging. Neuron 18:815-826.
    • (1997) Neuron , vol.18 , pp. 815-826
    • Song, H.1    Ming, G.2    Fon, E.3    Bellocchio, E.4    Edwards, R.H.5    Poo, M.6
  • 25
    • 17544366949 scopus 로고    scopus 로고
    • Modification of the pH profile and tetrabenazine sensitivity of rat VMAT1 by replacement of aspartate 404 with glutamate
    • Steiner-Mordoch S, Shirvan A and Schuldiner S (1996) Modification of the pH profile and tetrabenazine sensitivity of rat VMAT1 by replacement of aspartate 404 with glutamate. J Biol Chem 271:13048-13054.
    • (1996) J Biol Chem , vol.271 , pp. 13048-13054
    • Steiner-Mordoch, S.1    Shirvan, A.2    Schuldiner, S.3
  • 26
    • 0032493741 scopus 로고    scopus 로고
    • Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2
    • Tamai I, Ohashi R, Nezu J-i, Yabuuchi H, Oku A, Shimane M, Sai Y and Tsuji A (1998) Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2. J Biol Chem 273:20378-20382.
    • (1998) J Biol Chem , vol.273 , pp. 20378-20382
    • Tamai, I.1    Ohashi, R.2    Nezu, J.-I.3    Yabuuchi, H.4    Oku, A.5    Shimane, M.6    Sai, Y.7    Tsuji, A.8
  • 27
    • 0031434178 scopus 로고    scopus 로고
    • Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1
    • Tamai I, Yabuuchi H, Nezu J-i, Sai Y, Oku A, Shimane M and Tsuji A (1997) Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1. FEBS Lett 419:107-111.
    • (1997) FEBS Lett , vol.419 , pp. 107-111
    • Tamai, I.1    Yabuuchi, H.2    Nezu, J.-I.3    Sai, Y.4    Oku, A.5    Shimane, M.6    Tsuji, A.7
  • 28
    • 0026723769 scopus 로고
    • Asp-51 and Asp-120 are important for the transport function of the Escherichia coli melibiose carrier
    • Wilson DM and Wilson TH (1992) Asp-51 and Asp-120 are important for the transport function of the Escherichia coli melibiose carrier. J Bacteriol 174:3083-3086.
    • (1992) J Bacteriol , vol.174 , pp. 3083-3086
    • Wilson, D.M.1    Wilson, T.H.2
  • 30
    • 0032577202 scopus 로고    scopus 로고
    • cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family
    • Wu X, Prasad PD, Leibach FH and Ganapathy V (1998) cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family. Biochem Biophys Res Commun 246:589-595.
    • (1998) Biochem Biophys Res Commun , vol.246 , pp. 589-595
    • Wu, X.1    Prasad, P.D.2    Leibach, F.H.3    Ganapathy, V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.