ABCC2/Abcc2: A multispecific transporter with dominant excretory functions

Drug Metabolism Reviews

Volumn 42, Issue 3, 2010, Pages 402-436

  Jemnitz, Katalin ^a   Heredi Szabo, Krisztina ^b   Janossy, Judit ^b   Ioja, Eniko ^b   Vereczkey, Laszlo ^a   Krajcsi, Peter ^b  

^a CHEMICAL RESEARCH CENTER   (Hungary)

^b SOLVO BIOTECHNOLOGY   (Hungary)

Author keywords

ABC transporter; ABCC2; ADME; Conjugate hyperbilirubinemia; Dubin Johnson syndrome; MRP2; Pharmacokinetics; Toxicity

Indexed keywords

ANION; AZITHROMYCIN; BILIRUBIN; CEFOPERAZONE; CISPLATIN; DOXORUBICIN; EZETIMIBE; FEXOFENADINE; GEMFIBROZIL; GLUCURONIDE; GREPAFLOXACIN; INDINAVIR; INDOMETACIN; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 2; MYCOPHENOLIC ACID; NUTRACEUTICAL; OLMESARTAN; PARACETAMOL SULFATE; PRAVASTATIN; PROBENECID; ROSUVASTATIN; SULFATE; TELITHROMYCIN; THYROXINE; TOXIC SUBSTANCE; UNINDEXED DRUG; VALPROIC ACID; VALSARTAN; XENOBIOTIC AGENT; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2;

ANION TRANSPORT; AREA UNDER THE CURVE; BINDING SITE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; DRUG EXCRETION; DUBIN JOHNSON SYNDROME; EPITHELIUM CELL; GENE MUTATION; HUMAN; HYPERBILIRUBINEMIA; IN VITRO STUDY; IN VIVO STUDY; INTESTINE CELL; KIDNEY PROXIMAL TUBULE; LARGE INTESTINE; LIVER CELL; MAXIMUM PLASMA CONCENTRATION; MOLECULAR CLONING; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PATHOGENESIS; PHENOTYPE; PLACENTA; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; SMALL INTESTINE; SYNCYTIOTROPHOBLAST; TRANSPORT KINETICS; ACTIVE TRANSPORT; ANIMAL; BIOSYNTHESIS; CHEMISTRY; GENETICS; KINETICS; KNOCKOUT MOUSE; METABOLISM; MOUSE; PROTEIN CONFORMATION;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CLONING, MOLECULAR; DRUG RESISTANCE, MULTIPLE; HUMANS; KINETICS; MICE; MICE, KNOCKOUT; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PROTEIN CONFORMATION; XENOBIOTICS;

EID: 77954358310     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.3109/03602530903491741     Document Type: Review

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