-
1
-
-
0034833039
-
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1
-
Arndt P, Volk C, Gorboulev V, Budiman T, Popp C, Ulzheimer-Teuber I, Akhoundova A, Koppatz S, Bamberg E, Nagel G, and Koepsell H. Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1. Am J Physiol Renal Physiol 281: F454-F468, 2001.
-
(2001)
Am J Physiol Renal Physiol
, vol.281
-
-
Arndt, P.1
Volk, C.2
Gorboulev, V.3
Budiman, T.4
Popp, C.5
Ulzheimer-Teuber, I.6
Akhoundova, A.7
Koppatz, S.8
Bamberg, E.9
Nagel, G.10
Koepsell, H.11
-
2
-
-
0037151099
-
The human organic cation transporter (hOCT2) recognizes the degree of substrate ionization
-
Barendt WM and Wright SH. The human organic cation transporter (hOCT2) recognizes the degree of substrate ionization. J Biol Chem 277: 22491-22496, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 22491-22496
-
-
Barendt, W.M.1
Wright, S.H.2
-
3
-
-
0034026485
-
NBD-TMA a novel fluorescent substrate of the peritubular organic cation transporter of renal proximal tubules
-
Bednarczyk D, Mash EA, Aavula BR, and Wright SH. NBD-TMA: a novel fluorescent substrate of the peritubular organic cation transporter of renal proximal tubules. Pflügers Arch 440: 184-192, 2000.
-
(2000)
Pflügers Arch
, vol.440
, pp. 184-192
-
-
Bednarczyk, D.1
Mash, E.A.2
Aavula, B.R.3
Wright, S.H.4
-
4
-
-
12644278786
-
Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1
-
Busch AE, Quester S, Ulzheimer JC, Waldegger S, Gorboulev V, Arndt P, Lang F, and Koepsell H. Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1. J Biol Chem 271: 32599-32604, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 32599-32604
-
-
Busch, A.E.1
Quester, S.2
Ulzheimer, J.C.3
Waldegger, S.4
Gorboulev, V.5
Arndt, P.6
Lang, F.7
Koepsell, H.8
-
5
-
-
0037303577
-
Regulation of human organic cation transporter hOCT2 by PKA, PI3K, and calmodulin-dependent kinases
-
Cetinkaya I, Ciarimboli G, Yalcinkaya G, Mehrens T, Velic A, Hirsch JR, Gorboulev V, Koepsell H, and Schlatter E. Regulation of human organic cation transporter hOCT2 by PKA, PI3K, and calmodulin-dependent kinases. Am J Physiol Renal Physiol 284: F293-F302, 2003.
-
(2003)
Am J Physiol Renal Physiol
, vol.284
-
-
Cetinkaya, I.1
Ciarimboli, G.2
Yalcinkaya, G.3
Mehrens, T.4
Velic, A.5
Hirsch, J.R.6
Gorboulev, V.7
Koepsell, H.8
Schlatter, E.9
-
6
-
-
0034662431
-
Role of organic cation transporters in the renal secretion of nucleosides
-
Chen R and Nelson JA. Role of organic cation transporters in the renal secretion of nucleosides. Biochem Pharmacol 60: 215-219, 2000.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 215-219
-
-
Chen, R.1
Nelson, J.A.2
-
8
-
-
0034010850
-
Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1)
-
Dresser MJ, Gray AT, and Giacomini KM. Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1). J Pharmacol Exp Ther 292: 1146-1152, 2000.
-
(2000)
J Pharmacol Exp Ther
, vol.292
, pp. 1146-1152
-
-
Dresser, M.J.1
Gray, A.T.2
Giacomini, K.M.3
-
9
-
-
0033043795
-
Tetraethylammonium and amantadine identify distinct organic cation transporters in rat renal cortical proximal and distal tubules
-
Goralski KB and Sitar DS. Tetraethylammonium and amantadine identify distinct organic cation transporters in rat renal cortical proximal and distal tubules. J Pharmacol Exp Ther 290: 295-302, 1999.
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 295-302
-
-
Goralski, K.B.1
Sitar, D.S.2
-
10
-
-
0030763035
-
Cloning and characterization of two human polyspecific organic cation transporters
-
Gorboulev V, Ulzheimer JC, Akhoundova A, Ulzheimer-Teuber I, Karbach U, Quester S, Baumann C, Lang F, Busch AE, and Koepsell H. Cloning and characterization of two human polyspecific organic cation transporters. DNA Cell Biol 16: 871-881, 1997.
-
(1997)
DNA Cell Biol
, vol.16
, pp. 871-881
-
-
Gorboulev, V.1
Ulzheimer, J.C.2
Akhoundova, A.3
Ulzheimer-Teuber, I.4
Karbach, U.5
Quester, S.6
Baumann, C.7
Lang, F.8
Busch, A.E.9
Koepsell, H.10
-
11
-
-
0032723798
-
Selectivity of the polyspecific cation transporter rOCT is changed by mutation of aspartate 475 to glutamate
-
Gorboulev V, Volk C, Arndt P, Akhoundova A, and Koepsell H. Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate. Mol Pharmacol 56: 1254-1261, 1999.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 1254-1261
-
-
Gorboulev, V.1
Volk, C.2
Arndt, P.3
Akhoundova, A.4
Koepsell, H.5
-
13
-
-
0028063302
-
Drug excretion mediated by a new prototype of polyspecific transporter
-
Gründemann D, Gorboulev V, Gambaryan S, Veyhl M, and Koepsell H. Drug excretion mediated by a new prototype of polyspecific transporter. Nature 372: 549-552, 1994.
-
(1994)
Nature
, vol.372
, pp. 549-552
-
-
Gründemann, D.1
Gorboulev, V.2
Gambaryan, S.3
Veyhl, M.4
Koepsell, H.5
-
14
-
-
0019256661
-
Mechanisms of organic cation transport in kidney plasma membrane vesicles. 1. Countertransport studies
-
Holohan PD and Ross CR. Mechanisms of organic cation transport in kidney plasma membrane vesicles. 1. Countertransport studies. J Pharmacol Exp Ther 215: 191-197, 1980.
-
(1980)
J Pharmacol Exp Ther
, vol.215
, pp. 191-197
-
-
Holohan, P.D.1
Ross, C.R.2
-
15
-
-
0019485093
-
Mechanisms of organic cation transport in kidney plasma membrane vesicles. 2. ApH studies
-
Holohan PD and Ross CR. Mechanisms of organic cation transport in kidney plasma membrane vesicles. 2. ApH studies. J Pharmacol Exp Ther 216: 294-298, 1981.
-
(1981)
J Pharmacol Exp Ther
, vol.216
, pp. 294-298
-
-
Holohan, P.D.1
Ross, C.R.2
-
16
-
-
0033713246
-
Localization of organic cation transporters OCT1 and OCT2 in rat kidney
-
Karbach U, Kricke J, Meyer-Wentrup F, Gorboulev V, Volk C, Loffing-Cueni D, Kaissling B, Bachmann S, and Koepsell H. Localization of organic cation transporters OCT1 and OCT2 in rat kidney. Am J Physiol Renal Physiol 279: F679-F687, 2000.
-
(2000)
Am J Physiol Renal Physiol
, vol.279
-
-
Karbach, U.1
Kricke, J.2
Meyer-Wentrup, F.3
Gorboulev, V.4
Volk, C.5
Loffing-Cueni, D.6
Kaissling, B.7
Bachmann, S.8
Koepsell, H.9
-
17
-
-
0032569029
-
Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta
-
Kekuda R, Prasad PD, Wu X, Wang H, Fei YJ, Leibach FH, and Ganapathy V. Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta. J Biol Chem 273: 15971-15979, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 15971-15979
-
-
Kekuda, R.1
Prasad, P.D.2
Wu, X.3
Wang, H.4
Fei, Y.J.5
Leibach, F.H.6
Ganapathy, V.7
-
18
-
-
0036020986
-
Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function
-
Leabman MK, Huang CC, Kawamoto M, Johns SJ, Stryke D, Ferrin TE, DeYoung J, Taylor T, Clark AG, Herskowitz I, and Giacomini KM. Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function. Pharmacogenetics 12: 395-405, 2002.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 395-405
-
-
Leabman, M.K.1
Huang, C.C.2
Kawamoto, M.3
Johns, S.J.4
Stryke, D.5
Ferrin, T.E.6
DeYoung, J.7
Taylor, T.8
Clark, A.G.9
Herskowitz, I.10
Giacomini, K.M.11
-
19
-
-
0025761101
-
+-D-glucose cotransport in human intestinal brush-border membrane vesicles using a fast sampling, rapid filtration apparatus
-
+-D-glucose cotransport in human intestinal brush-border membrane vesicles using a fast sampling, rapid filtration apparatus. J Membr Biol 122: 127-141, 1991.
-
(1991)
J Membr Biol
, vol.122
, pp. 127-141
-
-
Malo, C.1
Berteloot, A.2
-
20
-
-
0029841766
-
Transport of small organic cations in the rat liver. The role of the organic cation transporter OCT1
-
Martel F, Vetter T, Russ H, Gründemann D, Azevedo I, Koepsell H, and Schömig E. Transport of small organic cations in the rat liver. The role of the organic cation transporter OCT1. Naunyn-Schm Arch Pharmacol 354: 320-326, 1996.
-
(1996)
Naunyn-Schm Arch Pharmacol
, vol.354
, pp. 320-326
-
-
Martel, F.1
Vetter, T.2
Russ, H.3
Gründemann, D.4
Azevedo, I.5
Koepsell, H.6
Schömig, E.7
-
21
-
-
0036205460
-
Gene expression levels and immunolocalization of organic anion transporters in the human kidney
-
Motohashi H, Sakurai Y, Saito H, Masuda S, Urakami Y, Goto M, Fukatsu A, Ogawa O, and Inui KI. Gene expression levels and immunolocalization of organic anion transporters in the human kidney. J Am Soc Nephrol 13: 866-874, 2002.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 866-874
-
-
Motohashi, H.1
Sakurai, Y.2
Saito, H.3
Masuda, S.4
Urakami, Y.5
Goto, M.6
Fukatsu, A.7
Ogawa, O.8
Inui, K.I.9
-
22
-
-
0030590117
-
cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2
-
Okuda M, Saito H, Urakami Y, Takano M, and Inui KI. cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2. Biochem Biophys Res Commun 224: 500-507, 1996.
-
(1996)
Biochem Biophys Res Commun
, vol.224
, pp. 500-507
-
-
Okuda, M.1
Saito, H.2
Urakami, Y.3
Takano, M.4
Inui, K.I.5
-
23
-
-
0032966119
-
Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes
-
Okuda M, Urakami Y, Saito H, and Inui K. Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes. Biochim Biophys Acta 1417: 224-231, 1999.
-
(1999)
Biochim Biophys Acta
, vol.1417
, pp. 224-231
-
-
Okuda, M.1
Urakami, Y.2
Saito, H.3
Inui, K.4
-
24
-
-
0027133590
-
Mechanisms mediating renal secretion of organic anions and cations
-
Pritchard JB and Miller DS. Mechanisms mediating renal secretion of organic anions and cations. Physiol Rev 73: 765-796, 1993.
-
(1993)
Physiol Rev
, vol.73
, pp. 765-796
-
-
Pritchard, J.B.1
Miller, D.S.2
-
25
-
-
0343603660
-
A functional-phylogenetic classification system for transmembrane solute transporters
-
Saier MH Jr. A functional-phylogenetic classification system for transmembrane solute transporters. Microbiol Mol Biol Rev 64: 354-411, 2000.
-
(2000)
Microbiol Mol Biol Rev
, vol.64
, pp. 354-411
-
-
Saier Jr., M.H.1
-
28
-
-
0036782039
-
The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP
-
Schlatter E, Monnich V, Cetinkaya I, Mehrens T, Ciarimboli G, Hirsch JR, Popp C, and Koepsell H. The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP. J Membr Biol 189: 237-244, 2002.
-
(2002)
J Membr Biol
, vol.189
, pp. 237-244
-
-
Schlatter, E.1
Monnich, V.2
Cetinkaya, I.3
Mehrens, T.4
Ciarimboli, G.5
Hirsch, J.R.6
Popp, C.7
Koepsell, H.8
-
29
-
-
0038184179
-
Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1
-
Shu Y, Leabman MK, Feng B, Mangravite LM, Huang CC, Stryke D, Kawamoto M, Johns SJ, DeYoung J, Carlson E, Ferrin TE, Herskowitz I, and Giacomini KM. Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1. Proc Natl Acad Sci USA 100: 5902-35907, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5902-35907
-
-
Shu, Y.1
Leabman, M.K.2
Feng, B.3
Mangravite, L.M.4
Huang, C.C.5
Stryke, D.6
Kawamoto, M.7
Johns, S.J.8
DeYoung, J.9
Carlson, E.10
Ferrin, T.E.11
Herskowitz, I.12
Giacomini, K.M.13
-
30
-
-
0036146331
-
Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels
-
Slitt AL, Cherrington NJ, Hartley DP, Leazer TM, and Klaassen CD. Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels. Drug Metab Dispos 30: 212-219, 2002.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 212-219
-
-
Slitt, A.L.1
Cherrington, N.J.2
Hartley, D.P.3
Leazer, T.M.4
Klaassen, C.D.5
-
31
-
-
0033387911
-
rOCT2 is a basolateral potential-driven carrier, not an organic cation/proton exchanger
-
Sweet DH and Pritchard JB. rOCT2 is a basolateral potential-driven carrier, not an organic cation/proton exchanger. Am J Physiol Renal Physiol 277: F890-F898, 1999.
-
(1999)
Am J Physiol Renal Physiol
, vol.277
-
-
Sweet, D.H.1
Pritchard, J.B.2
-
32
-
-
0021255131
-
Carrier-mediated transport systems of tetraethylammonium in rat renal brush-border and basolateral membrane vesicles
-
Takano M, Inui KI, Okano T, Saito H, and Hori R. Carrier-mediated transport systems of tetraethylammonium in rat renal brush-border and basolateral membrane vesicles. Biochim Biophys Acta 773: 113-124, 1984.
-
(1984)
Biochim Biophys Acta
, vol.773
, pp. 113-124
-
-
Takano, M.1
Inui, K.I.2
Okano, T.3
Saito, H.4
Hori, R.5
-
33
-
-
0032456205
-
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs
-
Urakami Y, Okuda M, Masuda S, Saito H, and Inui KI. Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs. J Pharmacol Exp Ther 287: 800-805, 1998.
-
(1998)
J Pharmacol Exp Ther
, vol.287
, pp. 800-805
-
-
Urakami, Y.1
Okuda, M.2
Masuda, S.3
Saito, H.4
Inui, K.I.5
-
34
-
-
0023499741
-
Transport of tetraethylammonium by rabbit renal brush-border and basolateral membrane vesicles
-
Wright SH and Wunz TM. Transport of tetraethylammonium by rabbit renal brush-border and basolateral membrane vesicles. Am J Physiol Renal Fluid Electrolyte Physiol 253: F1040-F1050, 1987.
-
(1987)
Am J Physiol Renal Fluid Electrolyte Physiol
, vol.253
-
-
Wright, S.H.1
Wunz, T.M.2
-
35
-
-
0033829943
-
Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney
-
Wu X, Huang W, Ganapathy ME, Wang H, Kekuda R, Conway SJ, Leibach FH, and Ganapathy V. Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney. Am J Physiol Renal Physiol 279: F449-F458, 2000.
-
(2000)
Am J Physiol Renal Physiol
, vol.279
-
-
Wu, X.1
Huang, W.2
Ganapathy, M.E.3
Wang, H.4
Kekuda, R.5
Conway, S.J.6
Leibach, F.H.7
Ganapathy, V.8
-
36
-
-
0031800792
-
Role of organic cation transporters in drug absorption and elimination
-
Zhang L, Brett CM, and Giacomini KM. Role of organic cation transporters in drug absorption and elimination. Annu Rev Pharmacol Toxicol 38: 431-460, 1998.
-
(1998)
Annu Rev Pharmacol Toxicol
, vol.38
, pp. 431-460
-
-
Zhang, L.1
Brett, C.M.2
Giacomini, K.M.3
-
37
-
-
0031846917
-
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa)
-
Zhang L, Schaner ME, and Giacomini KM. Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa). J Pharmacol Exp Ther 286: 354-361, 1998.
-
(1998)
J Pharmacol Exp Ther
, vol.286
, pp. 354-361
-
-
Zhang, L.1
Schaner, M.E.2
Giacomini, K.M.3
-
38
-
-
0036088549
-
Molecular cloning of rabbit organic cation transporter rbOCT2 and functional comparisons with rbOCT1
-
Zhang X, Evans KK, and Wright SH. Molecular cloning of rabbit organic cation transporter rbOCT2 and functional comparisons with rbOCT1. Am J Physiol Renal Physiol 283: F124-F133, 2002.
-
(2002)
Am J Physiol Renal Physiol
, vol.283
-
-
Zhang, X.1
Evans, K.K.2
Wright, S.H.3
|