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Volumn 285, Issue 6 54-6, 2003, Pages

Functional mapping of rbOCT1 and rbOCT2 activity in the S2 segment of rabbit proximal tubule

Author keywords

Cimetidine; Kidney; Organic cation; Tetraethylammonium; Transport

Indexed keywords

CIMETIDINE; ORGANIC CATION TRANSPORTER; ORGANIC CATION TRANSPORTER 2; PINDOLOL; TETRYLAMMONIUM; TYRAMINE; UNCLASSIFIED DRUG;

EID: 0242497252     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00112.2003     Document Type: Article
Times cited : (28)

References (38)
  • 2
    • 0037151099 scopus 로고    scopus 로고
    • The human organic cation transporter (hOCT2) recognizes the degree of substrate ionization
    • Barendt WM and Wright SH. The human organic cation transporter (hOCT2) recognizes the degree of substrate ionization. J Biol Chem 277: 22491-22496, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 22491-22496
    • Barendt, W.M.1    Wright, S.H.2
  • 3
    • 0034026485 scopus 로고    scopus 로고
    • NBD-TMA a novel fluorescent substrate of the peritubular organic cation transporter of renal proximal tubules
    • Bednarczyk D, Mash EA, Aavula BR, and Wright SH. NBD-TMA: a novel fluorescent substrate of the peritubular organic cation transporter of renal proximal tubules. Pflügers Arch 440: 184-192, 2000.
    • (2000) Pflügers Arch , vol.440 , pp. 184-192
    • Bednarczyk, D.1    Mash, E.A.2    Aavula, B.R.3    Wright, S.H.4
  • 6
    • 0034662431 scopus 로고    scopus 로고
    • Role of organic cation transporters in the renal secretion of nucleosides
    • Chen R and Nelson JA. Role of organic cation transporters in the renal secretion of nucleosides. Biochem Pharmacol 60: 215-219, 2000.
    • (2000) Biochem Pharmacol , vol.60 , pp. 215-219
    • Chen, R.1    Nelson, J.A.2
  • 8
    • 0034010850 scopus 로고    scopus 로고
    • Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1)
    • Dresser MJ, Gray AT, and Giacomini KM. Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1). J Pharmacol Exp Ther 292: 1146-1152, 2000.
    • (2000) J Pharmacol Exp Ther , vol.292 , pp. 1146-1152
    • Dresser, M.J.1    Gray, A.T.2    Giacomini, K.M.3
  • 9
    • 0033043795 scopus 로고    scopus 로고
    • Tetraethylammonium and amantadine identify distinct organic cation transporters in rat renal cortical proximal and distal tubules
    • Goralski KB and Sitar DS. Tetraethylammonium and amantadine identify distinct organic cation transporters in rat renal cortical proximal and distal tubules. J Pharmacol Exp Ther 290: 295-302, 1999.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 295-302
    • Goralski, K.B.1    Sitar, D.S.2
  • 11
    • 0032723798 scopus 로고    scopus 로고
    • Selectivity of the polyspecific cation transporter rOCT is changed by mutation of aspartate 475 to glutamate
    • Gorboulev V, Volk C, Arndt P, Akhoundova A, and Koepsell H. Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate. Mol Pharmacol 56: 1254-1261, 1999.
    • (1999) Mol Pharmacol , vol.56 , pp. 1254-1261
    • Gorboulev, V.1    Volk, C.2    Arndt, P.3    Akhoundova, A.4    Koepsell, H.5
  • 13
    • 0028063302 scopus 로고
    • Drug excretion mediated by a new prototype of polyspecific transporter
    • Gründemann D, Gorboulev V, Gambaryan S, Veyhl M, and Koepsell H. Drug excretion mediated by a new prototype of polyspecific transporter. Nature 372: 549-552, 1994.
    • (1994) Nature , vol.372 , pp. 549-552
    • Gründemann, D.1    Gorboulev, V.2    Gambaryan, S.3    Veyhl, M.4    Koepsell, H.5
  • 14
    • 0019256661 scopus 로고
    • Mechanisms of organic cation transport in kidney plasma membrane vesicles. 1. Countertransport studies
    • Holohan PD and Ross CR. Mechanisms of organic cation transport in kidney plasma membrane vesicles. 1. Countertransport studies. J Pharmacol Exp Ther 215: 191-197, 1980.
    • (1980) J Pharmacol Exp Ther , vol.215 , pp. 191-197
    • Holohan, P.D.1    Ross, C.R.2
  • 15
    • 0019485093 scopus 로고
    • Mechanisms of organic cation transport in kidney plasma membrane vesicles. 2. ApH studies
    • Holohan PD and Ross CR. Mechanisms of organic cation transport in kidney plasma membrane vesicles. 2. ApH studies. J Pharmacol Exp Ther 216: 294-298, 1981.
    • (1981) J Pharmacol Exp Ther , vol.216 , pp. 294-298
    • Holohan, P.D.1    Ross, C.R.2
  • 17
    • 0032569029 scopus 로고    scopus 로고
    • Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta
    • Kekuda R, Prasad PD, Wu X, Wang H, Fei YJ, Leibach FH, and Ganapathy V. Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta. J Biol Chem 273: 15971-15979, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 15971-15979
    • Kekuda, R.1    Prasad, P.D.2    Wu, X.3    Wang, H.4    Fei, Y.J.5    Leibach, F.H.6    Ganapathy, V.7
  • 19
    • 0025761101 scopus 로고
    • +-D-glucose cotransport in human intestinal brush-border membrane vesicles using a fast sampling, rapid filtration apparatus
    • +-D-glucose cotransport in human intestinal brush-border membrane vesicles using a fast sampling, rapid filtration apparatus. J Membr Biol 122: 127-141, 1991.
    • (1991) J Membr Biol , vol.122 , pp. 127-141
    • Malo, C.1    Berteloot, A.2
  • 22
    • 0030590117 scopus 로고    scopus 로고
    • cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2
    • Okuda M, Saito H, Urakami Y, Takano M, and Inui KI. cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2. Biochem Biophys Res Commun 224: 500-507, 1996.
    • (1996) Biochem Biophys Res Commun , vol.224 , pp. 500-507
    • Okuda, M.1    Saito, H.2    Urakami, Y.3    Takano, M.4    Inui, K.I.5
  • 23
    • 0032966119 scopus 로고    scopus 로고
    • Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes
    • Okuda M, Urakami Y, Saito H, and Inui K. Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes. Biochim Biophys Acta 1417: 224-231, 1999.
    • (1999) Biochim Biophys Acta , vol.1417 , pp. 224-231
    • Okuda, M.1    Urakami, Y.2    Saito, H.3    Inui, K.4
  • 24
    • 0027133590 scopus 로고
    • Mechanisms mediating renal secretion of organic anions and cations
    • Pritchard JB and Miller DS. Mechanisms mediating renal secretion of organic anions and cations. Physiol Rev 73: 765-796, 1993.
    • (1993) Physiol Rev , vol.73 , pp. 765-796
    • Pritchard, J.B.1    Miller, D.S.2
  • 25
    • 0343603660 scopus 로고    scopus 로고
    • A functional-phylogenetic classification system for transmembrane solute transporters
    • Saier MH Jr. A functional-phylogenetic classification system for transmembrane solute transporters. Microbiol Mol Biol Rev 64: 354-411, 2000.
    • (2000) Microbiol Mol Biol Rev , vol.64 , pp. 354-411
    • Saier Jr., M.H.1
  • 30
    • 0036146331 scopus 로고    scopus 로고
    • Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels
    • Slitt AL, Cherrington NJ, Hartley DP, Leazer TM, and Klaassen CD. Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels. Drug Metab Dispos 30: 212-219, 2002.
    • (2002) Drug Metab Dispos , vol.30 , pp. 212-219
    • Slitt, A.L.1    Cherrington, N.J.2    Hartley, D.P.3    Leazer, T.M.4    Klaassen, C.D.5
  • 31
    • 0033387911 scopus 로고    scopus 로고
    • rOCT2 is a basolateral potential-driven carrier, not an organic cation/proton exchanger
    • Sweet DH and Pritchard JB. rOCT2 is a basolateral potential-driven carrier, not an organic cation/proton exchanger. Am J Physiol Renal Physiol 277: F890-F898, 1999.
    • (1999) Am J Physiol Renal Physiol , vol.277
    • Sweet, D.H.1    Pritchard, J.B.2
  • 32
    • 0021255131 scopus 로고
    • Carrier-mediated transport systems of tetraethylammonium in rat renal brush-border and basolateral membrane vesicles
    • Takano M, Inui KI, Okano T, Saito H, and Hori R. Carrier-mediated transport systems of tetraethylammonium in rat renal brush-border and basolateral membrane vesicles. Biochim Biophys Acta 773: 113-124, 1984.
    • (1984) Biochim Biophys Acta , vol.773 , pp. 113-124
    • Takano, M.1    Inui, K.I.2    Okano, T.3    Saito, H.4    Hori, R.5
  • 33
    • 0032456205 scopus 로고    scopus 로고
    • Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs
    • Urakami Y, Okuda M, Masuda S, Saito H, and Inui KI. Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs. J Pharmacol Exp Ther 287: 800-805, 1998.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 800-805
    • Urakami, Y.1    Okuda, M.2    Masuda, S.3    Saito, H.4    Inui, K.I.5
  • 34
    • 0023499741 scopus 로고
    • Transport of tetraethylammonium by rabbit renal brush-border and basolateral membrane vesicles
    • Wright SH and Wunz TM. Transport of tetraethylammonium by rabbit renal brush-border and basolateral membrane vesicles. Am J Physiol Renal Fluid Electrolyte Physiol 253: F1040-F1050, 1987.
    • (1987) Am J Physiol Renal Fluid Electrolyte Physiol , vol.253
    • Wright, S.H.1    Wunz, T.M.2
  • 36
    • 0031800792 scopus 로고    scopus 로고
    • Role of organic cation transporters in drug absorption and elimination
    • Zhang L, Brett CM, and Giacomini KM. Role of organic cation transporters in drug absorption and elimination. Annu Rev Pharmacol Toxicol 38: 431-460, 1998.
    • (1998) Annu Rev Pharmacol Toxicol , vol.38 , pp. 431-460
    • Zhang, L.1    Brett, C.M.2    Giacomini, K.M.3
  • 37
    • 0031846917 scopus 로고    scopus 로고
    • Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa)
    • Zhang L, Schaner ME, and Giacomini KM. Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa). J Pharmacol Exp Ther 286: 354-361, 1998.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 354-361
    • Zhang, L.1    Schaner, M.E.2    Giacomini, K.M.3
  • 38
    • 0036088549 scopus 로고    scopus 로고
    • Molecular cloning of rabbit organic cation transporter rbOCT2 and functional comparisons with rbOCT1
    • Zhang X, Evans KK, and Wright SH. Molecular cloning of rabbit organic cation transporter rbOCT2 and functional comparisons with rbOCT1. Am J Physiol Renal Physiol 283: F124-F133, 2002.
    • (2002) Am J Physiol Renal Physiol , vol.283
    • Zhang, X.1    Evans, K.K.2    Wright, S.H.3


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