Multidrug resistance protein Mrp2 mediates ATP-dependent transport of classic renal organic anion p-aminohippurate

American Journal of Physiology - Renal Physiology

Volumn 279, Issue 4 48-4, 2000, Pages

  Van Aubel, Rémon A M H ^a   Peters, Janny G P ^a   Masereeuw, Rosalinde ^a   Van Os, Carel H ^a   Russel, Frans G M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

2; Kidney; p aminohippurate organic anion transport; Proximal tubule

Indexed keywords

4 AMINOHIPPURIC ACID; ADENOSINE TRIPHOSPHATE; MULTIDRUG RESISTANCE PROTEIN;

4 AMINOHIPPURIC ACID CLEARANCE; ANIMAL CELL; ARTICLE; BRUSH BORDER; CELL CULTURE; GENE OVEREXPRESSION; ION TRANSPORT; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE ABSORPTION; NONHUMAN; PRIORITY JOURNAL; URINARY EXCRETION;

EID: 0033713976     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2000.279.4.f713     Document Type: Article

References (21)

1. Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions
2. Immunological distribution of an organic anion transport protein in rat liver and kidney
3. 4) in isolated plasma membrane vesicles
4. Studies on the orientation of brush-border membrane vesicles
5. Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3)
6. Transient expression of Oatp organic anion transporter in mammalian cells: Identification of candidate substrates
7. Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
8. Active Lucifer Yellow secretion in renal proximal tubule: Evidence for organic anion transport system crossover
9. Multiple pathways of organic anion secretion in renal proximal tubule revealed by confocal microscopy
10. Endothelin B receptor-mediated regulation of ATP-driven drug secretion in renal proximal tubule
11. mRNA distribution and membrane localization of the OAT-K1 organic anion transporter in rat renal tubules
12. Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: Comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole glucuronide
13. p-Aminohippurate transport in rat renal brush-border membranes: A potential-sensitive transport system and an anion exchanger
14. + gradient-dependent transport of p-aminohippurate in membrane vesicles from dog kidney cortex
15. Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney
16. Expression of the MRP2 gene-encoded conjugate export pump in human kidney proximal tubules and in renal cell carcinoma
17. Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules
18. Excretion of GSSG and glutathione conjugates mediated by MRP1 and cMOAT/MRP2
19. Mechanisms and interaction of vinblastine and reduced glutathione transport in membrane vesicles by the rabbit multidrug resistance protein Mrp2 expressed in insect cells
20. Molecular pharmacology of renal organic anion transporters
21. Adenosine triphosphate-dependent transport of anionic conjugates by the rabbit multidrug resistance-associated protein Mrp2 expressed in insect cells