The complexities of hepatic drug transport: Current knowledge and emerging concepts

Pharmaceutical Research

Volumn 21, Issue 5, 2004, Pages 719-735

  Chandra, Priyamvada ^a   Brouwer, Kim L R ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

ABC proteins; Drug disposition; Hepatic transport; Hepatobiliary; SLC proteins; Transporters

Indexed keywords

BILE SALT EXPORT PUMP PROTEIN; BOSENTAN; BREAST CANCER RESISTANCE PROTEIN; CAMPTOTHECIN; CARRIER PROTEIN; CERIVASTATIN; CISPLATIN; CYCLOSPORIN A; DIGOXIN; DOXORUBICIN; DOXORUBICINOL; ELACRIDAR; ETOPOSIDE; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5; MULTIDRUG RESISTANCE PROTEIN 6; MULTIDRUG RESISTANCE PROTEIN 7; MULTIDRUG RESISTANCE PROTEIN 8; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTING POLYPEPTIDE; PARACETAMOL GLUCURONIDE; QUINIDINE; SODIUM TAUROCHOLATE COTRANSPORTING POLYPEPTIDE; TAMOXIFEN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINCRISTINE;

DRUG DISPOSITION; DRUG TRANSPORT; ENZYME SPECIFICITY; GENETIC DIFFERENCE; HEPATOBILIARY SYSTEM; HUMAN; LIVER CLEARANCE; LIVER TOXICITY; METABOLIC REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BILE; BIOLOGICAL TRANSPORT, ACTIVE; CARRIER PROTEINS; HUMANS; LIVER; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS;

EID: 3542995726     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000026420.79421.8f     Document Type: Review

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