Inorganic mercury interacts with cysteine residues (C451 and C474) of hOCT2 to reduce its transport activity

American Journal of Physiology - Renal Physiology

Volumn 292, Issue 5, 2007, Pages

  Pelis, Ryan M ^a   Dangprapai, Yodying ^a   Wunz, Theresa M ^a   Wright, Stephen H ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Cysteine accessibility; HgCl2; Organic cation transport; Renal proximal tubule; Tetraethylammonium

Indexed keywords

ALANINE; CYSTEINE; MERCURY CHLORIDE; MUTANT PROTEIN; ORGANIC CATION TRANSPORTER 2; TETRYLAMMONIUM; THIOL DERIVATIVE;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; IC 50; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RECEPTOR AFFINITY; TOXICOKINETICS; TRANSPORT KINETICS; WILD TYPE;

EID: 34247849190     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00496.2006     Document Type: Article

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