Transporter studies with the 3-O-sulfate conjugate of 17α- ethinylestradiol: Assessment of human liver drug transporters

Drug Metabolism and Disposition

Volumn 38, Issue 7, 2010, Pages 1072-1082

  Han, Yong Hae ^a   Busler, Dennis ^a   Hong, Yang ^a   Tian, Yuan ^a   Chen, Cliff ^a   Rodrigues, A David ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17ALPHA ETHINYLESTRADIOL 3 O SULFATE; 4 AMINOHIPPURIC ACID; ADENOSINE TRIPHOSPHATE; BREAST CANCER RESISTANCE PROTEIN; BROMSULFOPHTHALEIN; CARRIER PROTEIN; DRUG METABOLITE; ETHINYLESTRADIOL; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 1B1; ORGANIC ANION TRANSPORTER 2; ORGANIC ANION TRANSPORTER 2B1; SODIUM TAUROCHOLATE COTRANSPORTING POLYPEPTIDE; TETRYLAMMONIUM; UNCLASSIFIED DRUG; ETHINYLESTRADIOL-3-SULFATE; MATE1 PROTEIN, HUMAN; MULTIDRUG RESISTANCE PROTEIN; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 3; ORGANIC CATION TRANSPORTER; SLC22A2 PROTEIN, HUMAN; SLC22A9 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; CRYOPRESERVATION; DRUG BILE LEVEL; DRUG UPTAKE; HUMAN; HUMAN CELL; KIDNEY CELL; LIVER CELL; MEMBRANE VESICLE; MICHAELIS CONSTANT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TEMPERATURE DEPENDENCE; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DOG; DRUG EFFECTS; ENZYME SPECIFICITY; GENETIC TRANSFECTION; GENETICS; INSECT; KIDNEY; KINETICS; METABOLISM; PROCEDURES; TRANSFORMED CELL LINE; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELL LINE, TRANSFORMED; DOGS; ETHINYL ESTRADIOL; HUMANS; INSECTS; KIDNEY; KINETICS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; ORGANIC ANION TRANSPORT PROTEIN 1; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; ORGANIC CATION TRANSPORT PROTEINS; SUBSTRATE SPECIFICITY; TRANSFECTION;

EID: 77953784269     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.109.031518     Document Type: Article

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