-
1
-
-
0025949056
-
Hepatic nuclear factor 1 (HNF1) shows a wider distribution than products of its known target genes in developing mouse
-
Blumenfeld M, Maury M, Chouard T, Yaniv M, and Condamine H (1991) Hepatic nuclear factor 1 (HNF1) shows a wider distribution than products of its known target genes in developing mouse. Development 113:589-599.
-
(1991)
Development
, vol.113
, pp. 589-599
-
-
Blumenfeld, M.1
Maury, M.2
Chouard, T.3
Yaniv, M.4
Condamine, H.5
-
2
-
-
2442700344
-
Rat and mouse differences in gender-predominant expression of organic anion transporter (Oat1-3; Slc22a6-8) mRNA levels
-
Buist SC and Klaassen CD (2004) Rat and mouse differences in gender-predominant expression of organic anion transporter (Oat1-3; Slc22a6-8) mRNA levels. Drug Metab Dispos 32:620-625.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 620-625
-
-
Buist, S.C.1
Klaassen, C.D.2
-
3
-
-
0028148776
-
Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos
-
Chen WS, Manova K, Weinstein DC, Duncan SA, Plump AS, Prezioso VR, Bachvarova RF, and Darnell JE Jr (1994) Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. Genes Dev 8:2466-2477.
-
(1994)
Genes Dev
, vol.8
, pp. 2466-2477
-
-
Chen, W.S.1
Manova, K.2
Weinstein, D.C.3
Duncan, S.A.4
Plump, A.S.5
Prezioso, V.R.6
Bachvarova, R.F.7
Darnell Jr, J.E.8
-
4
-
-
0034852408
-
Human renal organic anion transporter 1 (hOAT1) and its role in the nephrotoxicity of antiviral nucleotide analogs
-
Cihlar T, Ho ES, Lin DC, and Mulato AS (2001) Human renal organic anion transporter 1 (hOAT1) and its role in the nephrotoxicity of antiviral nucleotide analogs. Nucleosides Nucleotides Nucleic Acids 20:641-648.
-
(2001)
Nucleosides Nucleotides Nucleic Acids
, vol.20
, pp. 641-648
-
-
Cihlar, T.1
Ho, E.S.2
Lin, D.C.3
Mulato, A.S.4
-
5
-
-
0030042979
-
Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes
-
Drewes T, Senkel S, Holewa B, and Ryffel GU (1996) Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes. Mol Cell Biol 16:925-931.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 925-931
-
-
Drewes, T.1
Senkel, S.2
Holewa, B.3
Ryffel, G.U.4
-
6
-
-
26244449838
-
Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease
-
Enomoto A and Endou H (2005) Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease. Clin Exp Nephrol 9:195-205.
-
(2005)
Clin Exp Nephrol
, vol.9
, pp. 195-205
-
-
Enomoto, A.1
Endou, H.2
-
7
-
-
0037427506
-
Organic anion and cation transporters occur in pairs of similar and similarly expressed genes
-
Eraly SA, Hamilton BA, and Nigam SK (2003) Organic anion and cation transporters occur in pairs of similar and similarly expressed genes. Biochem Biophys Res Commun 300:333-342.
-
(2003)
Biochem Biophys Res Commun
, vol.300
, pp. 333-342
-
-
Eraly, S.A.1
Hamilton, B.A.2
Nigam, S.K.3
-
8
-
-
33646165531
-
Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice
-
Eraly SA, Vallon V, Vaughn DA, Gangoiti JA, Richter K, Nagle M, Monte JC, Rieg T, Truong DM, Long JM, et al. (2006) Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. J Biol Chem 281:5072-5083.
-
(2006)
J Biol Chem
, vol.281
, pp. 5072-5083
-
-
Eraly, S.A.1
Vallon, V.2
Vaughn, D.A.3
Gangoiti, J.A.4
Richter, K.5
Nagle, M.6
Monte, J.C.7
Rieg, T.8
Truong, D.M.9
Long, J.M.10
-
9
-
-
0032103013
-
DNA binding and transcription activation specificity of hepatocyte nuclear factor 4
-
Fraser JD, Martinez V, Straney R, and Briggs MR (1998) DNA binding and transcription activation specificity of hepatocyte nuclear factor 4. Nucleic Acids Res 26:2702-2707.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 2702-2707
-
-
Fraser, J.D.1
Martinez, V.2
Straney, R.3
Briggs, M.R.4
-
10
-
-
2342508500
-
A transcriptional network in polycystic kidney disease
-
Gresh L, Fischer E, Reimann A, Tanguy M, Garbay S, Shao X, Hiesberger T, Fiette L, Igarashi P, Yaniv M, et al. (2004) A transcriptional network in polycystic kidney disease. EMBO J 23:1657-1668.
-
(2004)
EMBO J
, vol.23
, pp. 1657-1668
-
-
Gresh, L.1
Fischer, E.2
Reimann, A.3
Tanguy, M.4
Garbay, S.5
Shao, X.6
Hiesberger, T.7
Fiette, L.8
Igarashi, P.9
Yaniv, M.10
-
11
-
-
0034008388
-
Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1
-
Ho ES, Lin DC, Mendel DB, and Cihlar T (2000) Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1. J Am Soc Nephrol 11:383-393.
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 383-393
-
-
Ho, E.S.1
Lin, D.C.2
Mendel, D.B.3
Cihlar, T.4
-
12
-
-
0032919287
-
Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney
-
Hosoyamada M, Sekine T, Kanai Y, and Endou H (1999) Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney. Am J Physiol 276:F122-F128.
-
(1999)
Am J Physiol
, vol.276
-
-
Hosoyamada, M.1
Sekine, T.2
Kanai, Y.3
Endou, H.4
-
13
-
-
2442673685
-
Expression and localization of P1 promoter-driven hepatocyte nuclear factor-4α (HNF4α) isoforms in human and rats
-
Jiang S, Tanaka T, Iwanari H, Hotta H, Yamashita H, Kumakura J, Watanabe Y, Uchiyama Y, Aburatani H, Hamakubo T, et al. (2003) Expression and localization of P1 promoter-driven hepatocyte nuclear factor-4α (HNF4α) isoforms in human and rats. Nucl Recept 1:5.
-
(2003)
Nucl Recept
, vol.1
, pp. 5
-
-
Jiang, S.1
Tanaka, T.2
Iwanari, H.3
Hotta, H.4
Yamashita, H.5
Kumakura, J.6
Watanabe, Y.7
Uchiyama, Y.8
Aburatani, H.9
Hamakubo, T.10
-
14
-
-
0035813209
-
Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1α
-
Jung D, Hagenbuch B, Gresh L, Pontoglio M, Meier PJ, and Kullak-Ublick GA (2001) Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1α. J Biol Chem 276:37206-37214.
-
(2001)
J Biol Chem
, vol.276
, pp. 37206-37214
-
-
Jung, D.1
Hagenbuch, B.2
Gresh, L.3
Pontoglio, M.4
Meier, P.J.5
Kullak-Ublick, G.A.6
-
15
-
-
36348965458
-
Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1αβ and DNA methylation
-
Kikuchi R, Kusuhara H, Hattori N, Kim I, Shiota K, Gonzalez FJ, and Sugiyama Y (2007) Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1αβ and DNA methylation. Mol Pharmacol 72:1619-1625.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 1619-1625
-
-
Kikuchi, R.1
Kusuhara, H.2
Hattori, N.3
Kim, I.4
Shiota, K.5
Gonzalez, F.J.6
Sugiyama, Y.7
-
16
-
-
33747606242
-
Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1αβ and DNA methylation
-
Kikuchi R, Kusuhara H, Hattori N, Shiota K, Kim I, Gonzalez FJ, and Sugiyama Y (2006) Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1αβ and DNA methylation. Mol Pharmacol 70:887-896.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 887-896
-
-
Kikuchi, R.1
Kusuhara, H.2
Hattori, N.3
Shiota, K.4
Kim, I.5
Gonzalez, F.J.6
Sugiyama, Y.7
-
17
-
-
0026558715
-
LFB1 and LFB3 homeoproteins are sequentially expressed during kidney development
-
Lazzaro D, De Simone V, De Magistris L, Lehtonen E, and Cortese R (1992) LFB1 and LFB3 homeoproteins are sequentially expressed during kidney development. Development 114:469-479.
-
(1992)
Development
, vol.114
, pp. 469-479
-
-
Lazzaro, D.1
De Simone, V.2
De Magistris, L.3
Lehtonen, E.4
Cortese, R.5
-
18
-
-
0031944313
-
Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1α knockout mouse
-
Lee YH, Sauer B, and Gonzalez FJ (1998) Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1α knockout mouse. Mol Cell Biol 18:3059-3068.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3059-3068
-
-
Lee, Y.H.1
Sauer, B.2
Gonzalez, F.J.3
-
19
-
-
33745952758
-
Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1α
-
Maher JM, Slitt AL, Callaghan TN, Cheng X, Cheung C, Gonzalez FJ, and Klaassen CD (2006) Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1α. Biochem Pharmacol 72:512-522.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 512-522
-
-
Maher, J.M.1
Slitt, A.L.2
Callaghan, T.N.3
Cheng, X.4
Cheung, C.5
Gonzalez, F.J.6
Klaassen, C.D.7
-
20
-
-
0026027585
-
HNF-1, a member of a novel class of dimerizing homeodomain proteins
-
Mendel DB and Crabtree GR (1991) HNF-1, a member of a novel class of dimerizing homeodomain proteins. J Biol Chem 266:677-680.
-
(1991)
J Biol Chem
, vol.266
, pp. 677-680
-
-
Mendel, D.B.1
Crabtree, G.R.2
-
21
-
-
0028246642
-
Expression of the L-type pyruvate kinase gene and the hepatocyte nuclear factor 4 transcription factor in exocrine and endocrine pancreas
-
Miquerol L, Lopez S, Cartier N, Tulliez M, Raymondjean M, and Kahn A (1994) Expression of the L-type pyruvate kinase gene and the hepatocyte nuclear factor 4 transcription factor in exocrine and endocrine pancreas. J Biol Chem 269:8944-8951.
-
(1994)
J Biol Chem
, vol.269
, pp. 8944-8951
-
-
Miquerol, L.1
Lopez, S.2
Cartier, N.3
Tulliez, M.4
Raymondjean, M.5
Kahn, A.6
-
22
-
-
34447634890
-
Hepatocyte nuclear factor-4α regulates the human organic anion transporter 1 gene in the kidney
-
Ogasawara K, Terada T, Asaka J, Katsura T, and Inui K (2007) Hepatocyte nuclear factor-4α regulates the human organic anion transporter 1 gene in the kidney. Am J Physiol Renal Physiol 292:F1819-F1826.
-
(2007)
Am J Physiol Renal Physiol
, vol.292
-
-
Ogasawara, K.1
Terada, T.2
Asaka, J.3
Katsura, T.4
Inui, K.5
-
23
-
-
85047682066
-
NUBIScan, an in silico approach for prediction of nuclear receptor response elements
-
Podvinec M, Kaufmann MR, Handschin C, and Meyer UA (2002) NUBIScan, an in silico approach for prediction of nuclear receptor response elements. Mol Endocrinol 16:1269-1279.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 1269-1279
-
-
Podvinec, M.1
Kaufmann, M.R.2
Handschin, C.3
Meyer, U.A.4
-
24
-
-
0030031453
-
Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome
-
Pontoglio M, Barra J, Hadchouel M, Doyen A, Kress C, Bach JP, Babinet C, and Yaniv M (1996) Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome. Cell 84:575-585.
-
(1996)
Cell
, vol.84
, pp. 575-585
-
-
Pontoglio, M.1
Barra, J.2
Hadchouel, M.3
Doyen, A.4
Kress, C.5
Bach, J.P.6
Babinet, C.7
Yaniv, M.8
-
25
-
-
17844385785
-
The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4α and suppressed by bile acids
-
Popowski K, Eloranta JJ, Saborowski M, Fried M, Meier PJ, and Kullak-Ublick GA (2005) The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4α and suppressed by bile acids. Mol Pharmacol 67:1629-1638.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1629-1638
-
-
Popowski, K.1
Eloranta, J.J.2
Saborowski, M.3
Fried, M.4
Meier, P.J.5
Kullak-Ublick, G.A.6
-
26
-
-
28144436041
-
Hepatocyte nuclear factor-4α regulates the human apolipoprotein AV gene: Identification of a novel response element and involvement in the control by peroxisome proliferator-activated receptor-γ coactivator-1α, AMP-activated protein kinase, and mitogen-activated protein kinase pathway
-
Prieur X, Schaap FG, Coste H, and Rodriguez JC (2005) Hepatocyte nuclear factor-4α regulates the human apolipoprotein AV gene: identification of a novel response element and involvement in the control by peroxisome proliferator-activated receptor-γ coactivator-1α, AMP-activated protein kinase, and mitogen-activated protein kinase pathway. Mol Endocrinol 19:3107-3125.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 3107-3125
-
-
Prieur, X.1
Schaap, F.G.2
Coste, H.3
Rodriguez, J.C.4
-
27
-
-
0025775278
-
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
-
Rey-Campos J, Chouard T, Yaniv M, and Cereghini S (1991) vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1. EMBO J 10:1445-1457.
-
(1991)
EMBO J
, vol.10
, pp. 1445-1457
-
-
Rey-Campos, J.1
Chouard, T.2
Yaniv, M.3
Cereghini, S.4
-
28
-
-
33645870991
-
The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4α
-
Saborowski M, Kullak-Ublick GA, and Eloranta JJ (2006) The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4α. J Pharmacol Exp Ther 317:778-785.
-
(2006)
J Pharmacol Exp Ther
, vol.317
, pp. 778-785
-
-
Saborowski, M.1
Kullak-Ublick, G.A.2
Eloranta, J.J.3
-
30
-
-
0035072875
-
Hepatocyte nuclear factor-1α is an essential regulator of bile acid and plasma cholesterol metabolism
-
Shih DQ, Bussen M, Sehayek E, Ananthanarayanan M, Shneider BL, Suchy FJ, Shefer S, Bollileni JS, Gonzalez FJ, Breslow JL, et al. (2001) Hepatocyte nuclear factor-1α is an essential regulator of bile acid and plasma cholesterol metabolism. Nat Genet 27:375-382.
-
(2001)
Nat Genet
, vol.27
, pp. 375-382
-
-
Shih, D.Q.1
Bussen, M.2
Sehayek, E.3
Ananthanarayanan, M.4
Shneider, B.L.5
Suchy, F.J.6
Shefer, S.7
Bollileni, J.S.8
Gonzalez, F.J.9
Breslow, J.L.10
-
31
-
-
0025690311
-
Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
-
Sladek FM, Zhong WM, Lai E, and Darnell JE Jr (1990) Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev 4:2353-2365.
-
(1990)
Genes Dev
, vol.4
, pp. 2353-2365
-
-
Sladek, F.M.1
Zhong, W.M.2
Lai, E.3
Darnell Jr, J.E.4
-
32
-
-
0037178852
-
Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice
-
Sweet DH, Miller DS, Pritchard JB, Fujiwara Y, Beier DR, and Nigam SK (2002) Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice. J Biol Chem 277:26934-26943.
-
(2002)
J Biol Chem
, vol.277
, pp. 26934-26943
-
-
Sweet, D.H.1
Miller, D.S.2
Pritchard, J.B.3
Fujiwara, Y.4
Beier, D.R.5
Nigam, S.K.6
-
33
-
-
0026928723
-
HNF1, a homeoprotein member of the hepatic transcription regulatory network
-
Tronche F and Yaniv M (1992) HNF1, a homeoprotein member of the hepatic transcription regulatory network. Bioessays 14:579-587.
-
(1992)
Bioessays
, vol.14
, pp. 579-587
-
-
Tronche, F.1
Yaniv, M.2
|