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Volumn 39, Issue , 1999, Pages 361-398

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

Author keywords

ATP hydrolysis; Cancer chemotherapy; Chemosensitizer; Drug transport; Multidrug resistance; P glycoprotein

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; CARRIER PROTEIN; CHLOROQUINE; COLCHICINE; CYSTEINE DERIVATIVE; CYTOTOXIC AGENT; GLYCOPROTEIN P; MEPACRINE; PHENOTHIAZINE DERIVATIVE; PHENOXAZINE DERIVATIVE; PROPAFENONE; RESERPINE; STAUROSPORINE; VANADIC ACID; VERAPAMIL; XENOBIOTIC AGENT;

EID: 0032900953     PISSN: 03621642     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.pharmtox.39.1.361     Document Type: Review
Times cited : (1976)

References (16)
  • 2
    • 0010582318 scopus 로고    scopus 로고
    • Drug resistance: Alterations in drug uptake or extrusion
    • ed. JR Bertino, San Diego, CA: Academic
    • Gottesman MM, Pastan I. 1996. Drug resistance: alterations in drug uptake or extrusion. In Encyclopedia of Cancer, ed. JR Bertino, pp. 549-59. San Diego, CA: Academic
    • (1996) Encyclopedia of Cancer , pp. 549-559
    • Gottesman, M.M.1    Pastan, I.2
  • 3
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • Juliano RL, Ling V. 1976. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta 455:152-62
    • (1976) Biochim. Biophys. Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.2
  • 4
    • 0022972654 scopus 로고
    • Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
    • Chen C-J, Chin JE, Ueda K, Clark DP, Pastan I, et al. 1986. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell 47:381-89
    • (1986) Cell , vol.47 , pp. 381-389
    • Chen, C.-J.1    Chin, J.E.2    Ueda, K.3    Clark, D.P.4    Pastan, I.5
  • 5
    • 0023006005 scopus 로고
    • Isolation and expression of a complementary DNA that confers multidrug resistance
    • Gros P, Ben Neriah Y, Croop J, Housman DE. 1986. Isolation and expression of a complementary DNA that confers multidrug resistance. Nature 323:728-31
    • (1986) Nature , vol.323 , pp. 728-731
    • Gros, P.1    Ben Neriah, Y.2    Croop, J.3    Housman, D.E.4
  • 6
    • 0008632564 scopus 로고
    • Expression of a full-length cDNA for the human MDR1 gene confers resistance to colchicine, doxorubicin, and vinblastine
    • Ueda K, Cardarelli C, Gottesman MM, Pastan I.1987. Expression of a full-length cDNA for the human MDR1 gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc. Natl. Acad. Sci. USA 84:3004-8
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 3004-3008
    • Ueda, K.1    Cardarelli, C.2    Gottesman, M.M.3    Pastan, I.4
  • 7
    • 0024427595 scopus 로고
    • Expression of a human multidrug resistance cDNA (MDR1) in the bone marrow of transgenic mice: Resistance to daunomycin-induced leukopenia
    • Galski H, Sullivan M, Willingham MC, Chin KV, Gottesman MM, et al. 1989. Expression of a human multidrug resistance cDNA (MDR1) in the bone marrow of transgenic mice: resistance to daunomycin-induced leukopenia. Mol. Cell. Biol. 9:4357-63
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 4357-4363
    • Galski, H.1    Sullivan, M.2    Willingham, M.C.3    Chin, K.V.4    Gottesman, M.M.5
  • 8
    • 0024544045 scopus 로고
    • The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues
    • Croop JM, Raymond M, Haber D, Devault A, Arceci RJ, et al. 1989. The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues. Mol. Cell. Biol. 9:1346-50
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1346-1350
    • Croop, J.M.1    Raymond, M.2    Haber, D.3    Devault, A.4    Arceci, R.J.5
  • 9
    • 0345139075 scopus 로고
    • Functional role for the 170-to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies
    • Hamada H, Tsuruo T. 1986. Functional role for the 170-to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies. Proc. Natl. Acad. Sci. USA 83:7785-89
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 7785-7789
    • Hamada, H.1    Tsuruo, T.2
  • 10
    • 0023889448 scopus 로고
    • Tissue distribution of P-glycoprotein encoded by a multidrug-resistance gene as revealed by a monoclonal antibody MRK 16
    • Sugawara I, Kataoka I, Morishita Y, Hamada H, Tsuruo T, et al. 1988. Tissue distribution of P-glycoprotein encoded by a multidrug-resistance gene as revealed by a monoclonal antibody MRK 16. Cancer Res. 48:1926-29
    • (1988) Cancer Res. , vol.48 , pp. 1926-1929
    • Sugawara, I.1    Kataoka, I.2    Morishita, Y.3    Hamada, H.4    Tsuruo, T.5
  • 11
    • 0023447098 scopus 로고
    • Cellular localization of the multidrug resistance gene product P-glycoprotein in normal human tissues
    • Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, et al. 1987. Cellular localization of the multidrug resistance gene product P-glycoprotein in normal human tissues. Proc. Natl. Acad. Sci. USA 84:7735-38
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 7735-7738
    • Thiebaut, F.1    Tsuruo, T.2    Hamada, H.3    Gottesman, M.M.4    Pastan, I.5
  • 12
    • 0024576304 scopus 로고
    • Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein, P170: Evidence for localization in brain capillaries and cross-reactivity of one antibody with a muscle protein
    • Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, et al. 1989. Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein, P170: evidence for localization in brain capillaries and cross-reactivity of one antibody with a muscle protein. J. Histochem. Cytochem. 37:159-64
    • (1989) J. Histochem. Cytochem. , vol.37 , pp. 159-164
    • Thiebaut, F.1    Tsuruo, T.2    Hamada, H.3    Gottesman, M.M.4    Pastan, I.5
  • 13
    • 0031158805 scopus 로고    scopus 로고
    • The physiological function of drug-transporting P-glycoproteins
    • Schinkel AH. 1997. The physiological function of drug-transporting P-glycoproteins. Sem. Cancer Biol. 8:161-70
    • (1997) Sem. Cancer Biol. , vol.8 , pp. 161-170
    • Schinkel, A.H.1
  • 14
    • 0027458116 scopus 로고
    • ATP-dependent transport systems in bacteria and humans - Relevance to cystic fibrosis and multidrug resistance
    • Doige CA, Ames GFL. 1993. ATP-dependent transport systems in bacteria and humans - relevance to cystic fibrosis and multidrug resistance. Annu. Rev. Microbiol 47:291-319
    • (1993) Annu. Rev. Microbiol , vol.47 , pp. 291-319
    • Doige, C.A.1    Ames, G.F.L.2
  • 15
    • 0026621245 scopus 로고
    • ABC transporters: From microorganisms to man
    • Higgins CF. 1992. ABC transporters: from microorganisms to man. Annu. Rev. Cell. Biol. 8:67-13
    • (1992) Annu. Rev. Cell. Biol. , vol.8 , pp. 67-113
    • Higgins, C.F.1
  • 16
    • 0007630205 scopus 로고
    • ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells
    • Horio M, Gottesman MM, Pastan I.1988. ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells. Proc. Natl. Acad. Sci. USA 85:3580-84
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 3580-3584
    • Horio, M.1    Gottesman, M.M.2    Pastan, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.