Pathophysiological regulation of renal SLC22A organic ion transporters in acute kidney injury: Pharmacological and toxicological implications

Pharmacology and Therapeutics

Volumn 125, Issue 1, 2010, Pages 79-91

  Saito, Hideyuki ^a,b  

^a KUMAMOTO UNIVERSITY HOSPITAL   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Acute kidney injury; Indoxyl sulfate; Ischemia reperfusion; Nephrotoxicity; Renal tubular secretion; SLC22A transporter family

Indexed keywords

CARRIER PROTEIN; CISPLATIN; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPATOCYTE NUCLEAR FACTOR 1BETA; HEPATOCYTE NUCLEAR FACTOR 4; IMATINIB; INDICAN; MERCURY; MITOGEN ACTIVATED PROTEIN KINASE; ORGANIC CATION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 2; ORGANIC CATION TRANSPORTER 3; PROTEIN SLC22A; UNCLASSIFIED DRUG; URANYL NITRATE;

CELL MEMBRANE TRANSPORT; CHRONIC KIDNEY FAILURE; CHRONIC MYELOID LEUKEMIA; DRUG BLOOD LEVEL; DRUG CLEARANCE; GASTROINTESTINAL STROMAL TUMOR; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY DISEASE; KIDNEY FUNCTION; KIDNEY ISCHEMIA; KIDNEY PERFUSION; KIDNEY TUBULE ABSORPTION; NEPHROTOXICITY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SINGLE DRUG DOSE; SOLID TUMOR; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION; XENOBIOTIC METABOLISM;

ACUTE DISEASE; ANIMALS; GENE EXPRESSION REGULATION; HUMANS; ION TRANSPORT; KIDNEY; KIDNEY DISEASES; ORGANIC ANION TRANSPORTERS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT;

EID: 72049089059     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2009.09.008     Document Type: Review

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