Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione

Biochemical Journal

Volumn 338, Issue 2, 1999, Pages 393-401

  Paulusma, Coen C ^a   Van Geer, Michael A ^a   Evers, Raymond ^b   Heijn, Marc ^a   Ottenhoff, Roelof ^a   Borst, Piet ^b   Oude Elferink, Ronald P J ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

ABC transporters; Bile; Hepatocytes; Liver; Multidrug resistance

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; GLUTATHIONE; MULTIDRUG RESISTANCE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANION TRANSPORT; ARTICLE; BASOLATERAL MEMBRANE; BILIARY EXCRETION; CELL STRAIN; COMPETITIVE INHIBITION; CONTROLLED STUDY; DNA TRANSFECTION; MEMBRANE TRANSPORT; MEMBRANE VESICLE; MUTANT; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANION TRANSPORT PROTEINS; BILE CANALICULI; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELL LINE; DOGS; GLUTATHIONE; HUMANS; RATS; RATS, WISTAR;

EID: 0033104810     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3380393     Document Type: Article

References (41)

1. Oude Elferink, R. P. J., Meijer, D. K. F., Kuipers, F., Jansen, P. L. M., Groen, A. K. and Groothuis, G. M. M. (1995) Biochim. Biophys. Acta 1241, 215-268
2. Jansen, P. L. M., Peters, W. H. M. and Lamers, W. H. (1985) Hepatology 5, 573-579
3. Mikami, T., Nozaki, Y., Tagaya, O., Hosokawa, S., Nakura, T., Mori, H., Kondou, S., Matubara, Y. and Ohgoh, T. (1986) Gongen. Anom. 26, 250-251
4. Paulusma, C. C., Bosma, P. J., Zaman, G. J. R., Bakker, C. T. M., Otter, M., Scheffer, G. L., Scheper, R. J., Borst, P. and Oude Elferink, R. P. J. (1996) Science 271, 1126-1128
5. Büchler, M., König, J., Brom, M., Kartenbeck, J., Spring, H., Horie, T. and Keppler, D. (1996) J. Biol. Chem. 271, 15091-15098
6. Ito, K., Suzuki, H., Hirohashi, T., Kume, K., Shimizu, T. and Sugiyama, Y. (1997) Am. J. Physiol. 272, G16-G22
7. Taniguchi, K., Wada, M., Kohno, K., Nakamura, T., Kawabe, T., Kawakami, M., Kagotani, K., Okumura, K., Akiyama, S. and Kuwano, M. (1996) Cancer Res. 56, 4124-4129
8. Paulusma, C. C., Kool, M., Bosma, P. J., Scheffer, G. L., ter Borg, F., Scheper, R. J., Tytgat, G. N. J., Borst, P., Baas, F. and Oude Elferink, R. P. J. (1997) Hepatology 25, 1539-1542
9. Wada, M., Toh, S., Tanaguchi, K., Nakamura, T., Uchiumi, T., Kohno, K., Yoshida, I., Kimura, A., Sakisaka, S., Adachi, Y. and Kuwano, M. (1998) Hum. Mol. Gen. 7, 203-207
10. Loe, D. W., Deeley, R. and Cole, S. P. C. (1996) Eur. J. Cancer 32A, 945-957
11. Evers, R., Kool, M., van Deemter, L., Jansen, H., Calafat, J., Oomen, L. C. J. M., Paulusma, C. C., Oude Elferink, R. P. J., Baas, F., Schinkel, A. H. and Borst, P. (1998) J. Clin. Invest. 101, 1310-1319
12. Kool, M., de Haas, M., Scheffer, G. L. Scheper, R. J., van Eijck, M. J. T., Juijn, J. A., Baas, F. and Borst, P. (1997) Cancer Res. 57, 3537-3547
13. Keppler, D., Leier, I. and Jedlitschky, G. (1997) Biol. Chem. Hoppe-Seyler 378, 787-791
14. Zaman, G. J. R., Versantvoort, C. H. M., Smit, J. J. M., Eijdems, E. W. H. M., de Haas, M., Smit, A. J., Broxterman, H. J., Mulder, N. H., de Vries, E. G. E., Baas, F. and Borst, P. (1993) Cancer Res. 53, 1747-1750
15. Evers, R., Zaman, G. J. R., van Deemter, L., Jansen, H., Calafat, J., Oomen, L. C. J. M., Oude Elferink, R. P. J., Borst, P. and Schinkel, A. H. (1996) J. Clin. Invest. 97, 1-8
16. Oude Elferink, R. P. J., Ottenhoff, R., Liefting, W., de Haan, J. and Jansen, P. L. M. (1989) J. Clin. Invest. 84, 476-483
17. Ookhtens, M., Hobdy K., Corvasce M. C., Aw, T. Y. and Kaplowitz, N. (1985) J. Clin. Invest. 75, 258-265
18. Stein, A. F., Gregus, Z. and Klaassen, C. D. (1988) Toxicol. Appl. Pharmacol. 93, 351-359
19. Lauterburg, B. H., Smith, C. V., Hughes, H. and Mitchell, J. R. (1984) J. Clin. Invest. 73, 124-133
20. Fernandez-Checa, J. C., Takikawa, H., Horie, T., Ookhtens, M. and Kaplowitz, N. (1992) J. Biol. Chem. 267, 1667-1673
21. Heijn, M., Oude Elferink, R. P. J. and Jansen, P. L. M. (1992) Am. J. Physiol. 262, C104-C110
22. Tietze, F. (1969) Anal. Biochem. 27, 502-522
23. Evers, R., Cnubben, N. H., Wijnholds, J., van Deemter, L., van Bladeren, P. J. and Borst, P. (1997) FEBS Lett. 419, 112-116
24. Sacchetta, P., DiCola, D. and Federici, G. (1986) Anal. Biochem. 154, 205-208
25. Flens, M. J., Izquierdo, M. A., Scheffer, G. L., Fritz, J. M., Meier, C. J. L. M., Scheper, R. J. and Zaman, G. J. R. (1994) Cancer Res. 54, 4557-4563
26. Jansen, P. L. M., van Klinken, W. J., van Gelder, M., Ottenhoff, R. and Oude Elferink, R. P. J. (1993) Am. J. Physiol. 265, G445-G452
27. Inoue, M., Kinne, R., Tran, T. and Arias, I. M. (1983) Eur. J. Biochem. 134, 467-471
28. Kuipers, F., Radominska, A., Zimniak, P., van Dijk, T. H., Havinga, R., Vonk, R. J. and Lester, R. (1988) Hepatology 8, 1263
29. Ballatori, N. and Clarkson, T. W. (1985) Am. J. Physiol. 248, G238-G245
30. Yi, J., Fernandez-Checa, J. C. and Kaplowitz, N. (1994) J. Clin. Invest. 93, 1841-1845
31. Zaman, G. J. R., Lankelma, J., van Tellingen, O., Beijnen, J., Dekker, H., Paulusma, C. C., Oude Elferink, R. P. J., Baas, F. and Borst, P. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 7690-7694
32. Rappa, G., Lorico, A., Flavell, R. A. and Sartorelli, A. C. (1997) Cancer Res. 57, 5232-5237
33. Koike, K., Kawebe, T., Tanaka, T., Toh, S., Uchiumi, T., Wada, M., Akiyama, S-i., Ono, M. and Kuwano, M. (1997) Cancer Res. 57, 5475-5479
34. Gyurasics, A., Varga, F. and Gregus, Z. (1991) Biochem. Pharmacol. 41, 937-944
35. Gyurasics, A., Koszorus, L., Varga, F. and Gregus, Z. (1992) Biochem. Pharmacol. 44, 1275-1281
36. Scott, N., Hatlelid, K. M., MacKenzie, N. E. and Carter, D. E. (1993) Chem. Res. Toxicol. 6, 102-106
37. Loe, D. W., Almquist, K. C., Deeley, R. G. and Cole, S. P. C. (1996) J. Biol. Chem. 271, 9675-9682
38. Rebbeor, J. F., Connolly, G. C., Dumont, M. E. and Ballatori, N. (1998) Biochem. J. 334, 723-729
39. Rebbeor, J. F., Connolly, G. C., Dumont, M. E. and Ballatori, N. (1998) Hepatology 28, 423A
40. Szczypka, M. S., Wemmie, J. A., Moye-Rowley, W. S. and Thiele, D. J. (1994) J. Biol. Chem. 269, 22853-22857
41. Li, Z. S., Szczypka, M. S., Lu, Y. P., Thiele, D. J. and Rea, P. A. (1996) J. Biol. Chem. 271, 6509-6517