-
1
-
-
40349093664
-
The biochemistry of gout
-
Wortmann RL, Schumacher R Jr, Becker MA, Ryan LM, editors, New York: Taylor & Francis;
-
Becker MA. The biochemistry of gout. In: Wortmann RL, Schumacher R Jr, Becker MA, Ryan LM, editors. Crystal-induced arthropathies: gout, pseudogout and apatite-associated syndromes. New York: Taylor & Francis; 2006. pp. 189-212.
-
(2006)
Crystal-induced arthropathies: Gout, pseudogout and apatite-associated syndromes
, pp. 189-212
-
-
Becker, M.A.1
-
2
-
-
0037114923
-
Renal underexcretion of uric acid is present in patients with apparent high urinary uric acid output
-
Perez-Ruiz F, Calabozo M, Erauskin GG, et al. Renal underexcretion of uric acid is present in patients with apparent high urinary uric acid output. Arthritis Rheum 2002; 47:610-613.
-
(2002)
Arthritis Rheum
, vol.47
, pp. 610-613
-
-
Perez-Ruiz, F.1
Calabozo, M.2
Erauskin, G.G.3
-
3
-
-
33745274475
-
Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics
-
Current understanding of hyperuricemia with urate underexcretion is extensively reviewed
-
Terkeltaub R, Bushinsky DA, Becker MA. Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics. Arthritis Res Ther 2006; 8 (Suppl 1):S4. Current understanding of hyperuricemia with urate underexcretion is extensively reviewed.
-
(2006)
Arthritis Res Ther
, vol.8
, Issue.SUPPL. 1
-
-
Terkeltaub, R.1
Bushinsky, D.A.2
Becker, M.A.3
-
4
-
-
0033422249
-
Renal transport of urate in humans
-
Roch-Ramel F, Guisan B. Renal transport of urate in humans. News Physiol Sci 1999; 14:80-84.
-
(1999)
News Physiol Sci
, vol.14
, pp. 80-84
-
-
Roch-Ramel, F.1
Guisan, B.2
-
5
-
-
23844450407
-
Molecular physiology and the four-component model of renal urate transport
-
Mount DB. Molecular physiology and the four-component model of renal urate transport. Curr Opin Nephrol Hypertens 2005; 14:460-463.
-
(2005)
Curr Opin Nephrol Hypertens
, vol.14
, pp. 460-463
-
-
Mount, D.B.1
-
6
-
-
0037161834
-
Molecular identification of a renal urate anion exchanger that regulates blood urate levels
-
Enomoto A, Kimura H, Chairoungdua A, et al. Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature 2002; 417:447-452.
-
(2002)
Nature
, vol.417
, pp. 447-452
-
-
Enomoto, A.1
Kimura, H.2
Chairoungdua, A.3
-
7
-
-
33846837206
-
New insights into renal transport of urate
-
This is an extensive and excellent review of the urate transport in kidney
-
Anzai N, Kanai Y, Endou H. New insights into renal transport of urate. Curr Opin Rheumatol 2007; 19:151-157. This is an extensive and excellent review of the urate transport in kidney.
-
(2007)
Curr Opin Rheumatol
, vol.19
, pp. 151-157
-
-
Anzai, N.1
Kanai, Y.2
Endou, H.3
-
8
-
-
1842732504
-
Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules
-
Ekaratanawong S, Anzai N, Jutabha P, et al. Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules. J Pharmacol Sci 2004; 94:297-304.
-
(2004)
J Pharmacol Sci
, vol.94
, pp. 297-304
-
-
Ekaratanawong, S.1
Anzai, N.2
Jutabha, P.3
-
10
-
-
0041344601
-
Identification of a novel voltagedriven organic anion transporter present at apical membrane of renal proximal tubule
-
Jutabha P, Kanai Y, Hosoyamada M, et al. Identification of a novel voltagedriven organic anion transporter present at apical membrane of renal proximal tubule. J Biol Chem 2003; 278:27930-27938.
-
(2003)
J Biol Chem
, vol.278
, pp. 27930-27938
-
-
Jutabha, P.1
Kanai, Y.2
Hosoyamada, M.3
-
11
-
-
12144257103
-
Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites
-
Van Aubel RA, Smeets PH, van den Heuvel JJ, Russel FG. Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites. Am J Physiol Renal Physiol 2005; 288:F327-F333.
-
(2005)
Am J Physiol Renal Physiol
, vol.288
-
-
Van Aubel, R.A.1
Smeets, P.H.2
van den Heuvel, J.J.3
Russel, F.G.4
-
12
-
-
33645909146
-
Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins
-
Miyazaki H, Anzai N, Ekaratanawong S, et al. Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins. J Am Soc Nephrol 2005; 16:3498-3506.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 3498-3506
-
-
Miyazaki, H.1
Anzai, N.2
Ekaratanawong, S.3
-
13
-
-
34248148043
-
Sodium-hydrogen exchanger regulatory factor-1 interacts withmouse urate transporter 1 to regulate renal proximal tubule uric acid transport
-
Cunningham R, Brazie M, Kanumuru S, et al. Sodium-hydrogen exchanger regulatory factor-1 interacts withmouse urate transporter 1 to regulate renal proximal tubule uric acid transport. J Am Soc Nephrol 2007; 18:1419-1425.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1419-1425
-
-
Cunningham, R.1
Brazie, M.2
Kanumuru, S.3
-
15
-
-
0036198703
-
Gender-specific and developmental influences on the expression of rat organic anion transporters
-
Buist SC, Cherrington NJ, Choudhuri S, et al. Gender-specific and developmental influences on the expression of rat organic anion transporters. J Pharmacol Exp Ther 2002; 301:145-151.
-
(2002)
J Pharmacol Exp Ther
, vol.301
, pp. 145-151
-
-
Buist, S.C.1
Cherrington, N.J.2
Choudhuri, S.3
-
16
-
-
33847139479
-
Organic anion transporters of the SLC22 family: Biopharmaceutical, physiological, and pathological roles
-
This is an extensive review about the roles of the organic anion transporters in physiological and pathological conditions
-
Rizwan AN, Burckhardt G. Organic anion transporters of the SLC22 family: biopharmaceutical, physiological, and pathological roles. Pharm Res 2007; 24:450-470. This is an extensive review about the roles of the organic anion transporters in physiological and pathological conditions.
-
(2007)
Pharm Res
, vol.24
, pp. 450-470
-
-
Rizwan, A.N.1
Burckhardt, G.2
-
17
-
-
2942675119
-
Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition
-
Ljubojevic M, Herak-Kramberger CM, Hagos Y, et al. Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition. Am J Physiol Renal Physiol 2004; 287:F124-F138.
-
(2004)
Am J Physiol Renal Physiol
, vol.287
-
-
Ljubojevic, M.1
Herak-Kramberger, C.M.2
Hagos, Y.3
-
18
-
-
0942265459
-
Function and localization of urate transporter 1 in mouse kidney
-
Hosoyamada M, Ichida K, Enomoto A, et al. Function and localization of urate transporter 1 in mouse kidney. J Am Soc Nephrol 2004; 15:261-268.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 261-268
-
-
Hosoyamada, M.1
Ichida, K.2
Enomoto, A.3
-
19
-
-
9244264985
-
Molecular cloning and characterization of a human urate transporter (hURAT1) gene promoter
-
Li T, Walsh JR, Ghishan FK, Bai L. Molecular cloning and characterization of a human urate transporter (hURAT1) gene promoter. Biochim Biophys Acta 2004; 1681:53-58.
-
(2004)
Biochim Biophys Acta
, vol.1681
, pp. 53-58
-
-
Li, T.1
Walsh, J.R.2
Ghishan, F.K.3
Bai, L.4
-
21
-
-
7244236578
-
Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate
-
Gopal E, Fei YJ, Sugawara M, et al. Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate. J Biol Chem 2004; 279:44522-44532.
-
(2004)
J Biol Chem
, vol.279
, pp. 44522-44532
-
-
Gopal, E.1
Fei, Y.J.2
Sugawara, M.3
-
22
-
-
29644435407
-
Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2)
-
Srinivas SR, Gopal E, Zhuang L, et al. Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2). Biochem J 2005; 392:655-664.
-
(2005)
Biochem J
, vol.392
, pp. 655-664
-
-
Srinivas, S.R.1
Gopal, E.2
Zhuang, L.3
-
23
-
-
35848971238
-
Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney
-
This paper shows the localization of SMCT1/2 and provides evidence of the transport of lactate via these molecules
-
Gopal E, Umapathy NS, Martin PM, et al. Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney. Biochim Biophys Acta 2007; 1768:2690-2697. This paper shows the localization of SMCT1/2 and provides evidence of the transport of lactate via these molecules.
-
(2007)
Biochim Biophys Acta
, vol.1768
, pp. 2690-2697
-
-
Gopal, E.1
Umapathy, N.S.2
Martin, P.M.3
-
25
-
-
23644434855
-
A common mutation in an organic anion transporter gene, SLC22A12, is a suppressing factor for the development of gout
-
Taniguchi A, Urano W, Yamanaka M, et al. A common mutation in an organic anion transporter gene, SLC22A12, is a suppressing factor for the development of gout. Arthritis Rheum 2005; 52:2576-2577.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2576-2577
-
-
Taniguchi, A.1
Urano, W.2
Yamanaka, M.3
-
26
-
-
0346734163
-
Clinical and molecular analysis of patients with renal hypouricemia in Japan - influence of URAT1 gene on urinary urate excretion
-
Ichida K, Hosoyamada M, Hisatome I, et al. Clinical and molecular analysis of patients with renal hypouricemia in Japan - influence of URAT1 gene on urinary urate excretion. J Am Soc Nephrol 2004; 15:164-173.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 164-173
-
-
Ichida, K.1
Hosoyamada, M.2
Hisatome, I.3
-
27
-
-
3142674476
-
The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia
-
Komoda F, Sekine T, Inatomi J, et al. The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia. Pediatr Nephrol 2004; 19:728-733.
-
(2004)
Pediatr Nephrol
, vol.19
, pp. 728-733
-
-
Komoda, F.1
Sekine, T.2
Inatomi, J.3
-
28
-
-
31144433386
-
Association of the human urate transporter 1 with reduced renal uric acid excretion and hyperuricemia in a German Caucasian population
-
Graessler J, Graessler A, Unger S, et al. Association of the human urate transporter 1 with reduced renal uric acid excretion and hyperuricemia in a German Caucasian population. Arthritis Rheum 2006; 54:292-300.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 292-300
-
-
Graessler, J.1
Graessler, A.2
Unger, S.3
-
30
-
-
34547802776
-
Homozygous frameshift mutation in the SLC22A12 gene in a patient with primary gout and high levels of serum uric acid
-
Vazquez-Mellado J, Alvarado-Romano V, Burgos-Vargas R, et al. Homozygous frameshift mutation in the SLC22A12 gene in a patient with primary gout and high levels of serum uric acid. J Clin Pathol 2007; 60:947-948.
-
(2007)
J Clin Pathol
, vol.60
, pp. 947-948
-
-
Vazquez-Mellado, J.1
Alvarado-Romano, V.2
Burgos-Vargas, R.3
-
31
-
-
4344630808
-
A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese
-
Iwai N, Mino Y, Hosoyamada M, et al. A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese. Kidney Int 2004; 66:935-944.
-
(2004)
Kidney Int
, vol.66
, pp. 935-944
-
-
Iwai, N.1
Mino, Y.2
Hosoyamada, M.3
-
32
-
-
33750478368
-
Association between intronic SNP in urate-anion exchanger gene, SLC22A12, and serum uric acid levels in Japanese
-
Shima Y, Teruya K, Ohta H. Association between intronic SNP in urate-anion exchanger gene, SLC22A12, and serum uric acid levels in Japanese. Life Sci 2006; 79:2234-2237.
-
(2006)
Life Sci
, vol.79
, pp. 2234-2237
-
-
Shima, Y.1
Teruya, K.2
Ohta, H.3
-
33
-
-
0033850904
-
Localization of a gene for familial juvenile hyperuricemic nephropathy causing underexcretion-type gout to 16p12 by genome-wide linkage analysis of a large family
-
Kamatani N, Moritani M, Yamanaka H, et al. Localization of a gene for familial juvenile hyperuricemic nephropathy causing underexcretion-type gout to 16p12 by genome-wide linkage analysis of a large family. Arthritis Rheum 2000; 43:925-929.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 925-929
-
-
Kamatani, N.1
Moritani, M.2
Yamanaka, H.3
-
34
-
-
0033928339
-
Familial juvenile hyperuricemic nephropathy: Localization of the gene on chromosome 16p11.2 and evidence for genetic heterogeneity
-
Stiburkova B, Majewski J, Sebesta I, et al. Familial juvenile hyperuricemic nephropathy: localization of the gene on chromosome 16p11.2 and evidence for genetic heterogeneity. Am J Hum Genet 2000; 66:1989-1994.
-
(2000)
Am J Hum Genet
, vol.66
, pp. 1989-1994
-
-
Stiburkova, B.1
Majewski, J.2
Sebesta, I.3
-
35
-
-
0036914069
-
Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy
-
Hart TC, Gorry MC, Hart PS, et al. Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy. J Med Genet 2002; 39:882-892.
-
(2002)
J Med Genet
, vol.39
, pp. 882-892
-
-
Hart, T.C.1
Gorry, M.C.2
Hart, P.S.3
-
36
-
-
33749532096
-
Defective intracellular trafficking of uromodulin mutant isoforms
-
Bernascone I, Vavassori S, Di Pentima A, et al. Defective intracellular trafficking of uromodulin mutant isoforms. Traffic 2006; 7:1567-1579.
-
(2006)
Traffic
, vol.7
, pp. 1567-1579
-
-
Bernascone, I.1
Vavassori, S.2
Di Pentima, A.3
-
37
-
-
33846021647
-
Membrane targeting and secretion of mutant uromodulin in familial juvenile hyperuricemic nephropathy
-
Jennings P, Aydin S, Kotanko P, et al. Membrane targeting and secretion of mutant uromodulin in familial juvenile hyperuricemic nephropathy. J Am Soc Nephrol 2007; 18:264-273.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 264-273
-
-
Jennings, P.1
Aydin, S.2
Kotanko, P.3
-
38
-
-
33748413779
-
Alterations of uromodulin biology: A common denominator of the genetically heterogeneous FJHN/MCKD syndrome
-
A comprehensive study of the FJHN/MCKD phenotype using 19 families is described
-
Vylet'al P, Kublova M, Kalbacova M, et al. Alterations of uromodulin biology: a common denominator of the genetically heterogeneous FJHN/MCKD syndrome. Kidney Int 2006; 70:1155-1169. A comprehensive study of the FJHN/MCKD phenotype using 19 families is described.
-
(2006)
Kidney Int
, vol.70
, pp. 1155-1169
-
-
Vylet'al, P.1
Kublova, M.2
Kalbacova, M.3
-
39
-
-
2342453842
-
Familial juvenile hyperuricemic nephropathy: Detection of mutations in the uromodulin gene in five Japanese families
-
Kudo E, Kamatani N, Tezuka O, et al. Familial juvenile hyperuricemic nephropathy: detection of mutations in the uromodulin gene in five Japanese families. Kidney Int 2004; 65:1589-1597.
-
(2004)
Kidney Int
, vol.65
, pp. 1589-1597
-
-
Kudo, E.1
Kamatani, N.2
Tezuka, O.3
-
40
-
-
20044368467
-
Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice
-
Bachmann S, Mutig K, Bates J, et al. Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice. Am J Physiol Renal Physiol 2005; 288:F559-F567.
-
(2005)
Am J Physiol Renal Physiol
, vol.288
-
-
Bachmann, S.1
Mutig, K.2
Bates, J.3
-
41
-
-
33745622386
-
Is salt-wasting the long awaited answer to the hyperuricaemia seen in uromodulin storage diseases?
-
Gersch M, Mutig K, Bachmann S, et al. Is salt-wasting the long awaited answer to the hyperuricaemia seen in uromodulin storage diseases? Nephrol Dial Transplant 2006; 21:2028-2029.
-
(2006)
Nephrol Dial Transplant
, vol.21
, pp. 2028-2029
-
-
Gersch, M.1
Mutig, K.2
Bachmann, S.3
-
43
-
-
0037408284
-
Atypical familial juvenile hyperuricemic nephropathy associated with a hepatocyte nuclear factor-1beta gene mutation
-
Bingham C, Ellard S, van't Hoff WG, et al. Atypical familial juvenile hyperuricemic nephropathy associated with a hepatocyte nuclear factor-1beta gene mutation. Kidney Int 2003; 63:1645-1651.
-
(2003)
Kidney Int
, vol.63
, pp. 1645-1651
-
-
Bingham, C.1
Ellard, S.2
van't Hoff, W.G.3
-
44
-
-
2342508500
-
A transcriptional network in polycystic kidney disease
-
Gresh L, Fischer E, Reimann A, et al. A transcriptional network in polycystic kidney disease. EMBO J 2004; 23:1657-1668.
-
(2004)
EMBO J
, vol.23
, pp. 1657-1668
-
-
Gresh, L.1
Fischer, E.2
Reimann, A.3
-
45
-
-
31644431556
-
Mapping of a new candidate locus for uromodulin-associated kidney disease (UAKD) to chromosome 1q41
-
Hodanova K, Majewski J, Kublova M, et al. Mapping of a new candidate locus for uromodulin-associated kidney disease (UAKD) to chromosome 1q41. Kidney Int 2005; 68:1472-1482.
-
(2005)
Kidney Int
, vol.68
, pp. 1472-1482
-
-
Hodanova, K.1
Majewski, J.2
Kublova, M.3
|