-
1
-
-
34250794495
-
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks
-
Acosta-Alvear D, Zhou Y, Blais A, Tsikitis M, Lents NH, Arias C, Lennon CJ, Kluger Y, Dynlacht BD. XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks. Mol Cell 27: 53-66, 2007.
-
(2007)
Mol Cell
, vol.27
, pp. 53-66
-
-
Acosta-Alvear, D.1
Zhou, Y.2
Blais, A.3
Tsikitis, M.4
Lents, N.H.5
Arias, C.6
Lennon, C.J.7
Kluger, Y.8
Dynlacht, B.D.9
-
2
-
-
79952283168
-
Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response
-
Ali MM, Bagratuni T, Davenport EL, Nowak PR, Silva-Santisteban MC, Hardcastle A, McAndrews C, Rowlands MG, Morgan GJ, Aherne W, Collins I, Davies FE, Pearl LH. Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response. EMBO J 30: 894-905, 2011.
-
(2011)
EMBO J
, vol.30
, pp. 894-905
-
-
Ali, M.M.1
Bagratuni, T.2
Davenport, E.L.3
Nowak, P.R.4
Silva-Santisteban, M.C.5
Hardcastle, A.6
McAndrews, C.7
Rowlands, M.G.8
Morgan, G.J.9
Aherne, W.10
Collins, I.11
Davies, F.E.12
Pearl, L.H.13
-
3
-
-
28444474185
-
The gene disrupted in Marinesco-Sjögren syndrome encodes SIL1, an HSPA5 cochaperone
-
Anttonen AK, Mahjneh I, Hämäläinen RH, Lagier-Tourenne C, Kopra O, Waris L, Anttonen M, Joensuu T, Kalimo H, Paetau A, Tranebjaerg L, Chaigne D, Koenig M, Eeg-Olofsson O, Udd B, Somer M, Somer H, Lehesjoki AE. The gene disrupted in Marinesco-Sjögren syndrome encodes SIL1, an HSPA5 cochaperone. Nature Genet 37: 1309-1311, 2005.
-
(2005)
Nature Genet
, vol.37
, pp. 1309-1311
-
-
Anttonen, A.K.1
Mahjneh, I.2
Hämäläinen, R.H.3
Lagier-Tourenne, C.4
Kopra, O.5
Waris, L.6
Anttonen, M.7
Joensuu, T.8
Kalimo, H.9
Paetau, A.10
Tranebjaerg, L.11
Chaigne, D.12
Koenig, M.13
Eeg-Olofsson, O.14
Udd, B.15
Somer, M.16
Somer, H.17
Lehesjoki, A.E.18
-
4
-
-
59649092854
-
Messenger RNA targeting to endoplasmic reticulum stress signalling sites
-
Aragon T, van Anken E, Pincus D, Serafimova IM, Korennykh AV, Rubio CA, Walter P. Messenger RNA targeting to endoplasmic reticulum stress signalling sites. Nature 457: 736-740, 2009.
-
(2009)
Nature
, vol.457
, pp. 736-740
-
-
Aragon, T.1
van Anken, E.2
Pincus, D.3
Serafimova, I.M.4
Korennykh, A.V.5
Rubio, C.A.6
Walter, P.7
-
5
-
-
34548202772
-
Visiting the ER: The endoplasmic reticulum as a target for therapeutics in traffic related diseases
-
Aridor M. Visiting the ER: the endoplasmic reticulum as a target for therapeutics in traffic related diseases. Advanced Drug Delivery Rev 59: 759-781, 2007.
-
(2007)
Advanced Drug Delivery Rev
, vol.59
, pp. 759-781
-
-
Aridor, M.1
-
6
-
-
67650649726
-
A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathway
-
Arsham AM, Neufeld TP. A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathway. PLoS One 4: e6068, 2009.
-
(2009)
PLoS One
, vol.4
-
-
Arsham, A.M.1
Neufeld, T.P.2
-
7
-
-
77949883045
-
Hepatic Bax inhibitor-1 inhibits IRE1alpha and protects from obesityassociated insulin resistance and glucose intolerance
-
Bailly-Maitre B, Belgardt BF, Jordan SD, Coornaert B, von Freyend MJ, Kleinridders A, Mauer J, Cuddy M, Kress CL, Willmes D, Essig M, Hampel B, Protzer U, Reed JC, Bruning JC. Hepatic Bax inhibitor-1 inhibits IRE1alpha and protects from obesityassociated insulin resistance and glucose intolerance. J Biol Chem 285: 6198-6207, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 6198-6207
-
-
Bailly-Maitre, B.1
Belgardt, B.F.2
Jordan, S.D.3
Coornaert, B.4
von Freyend, M.J.5
Kleinridders, A.6
Mauer, J.7
Cuddy, M.8
Kress, C.L.9
Willmes, D.10
Essig, M.11
Hampel, B.12
Protzer, U.13
Reed, J.C.14
Bruning, J.C.15
-
8
-
-
33644515957
-
Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury
-
Bailly-Maitre B, Fondevila C, Kaldas F, Droin N, Luciano F, Ricci JE, Croxton R, Krajewska M, Zapata JM, Kupiec-Weglinski JW, Farmer D, Reed JC. Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury. Proc Natl Acad Sci USA 103: 2809-2814, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2809-2814
-
-
Bailly-Maitre, B.1
Fondevila, C.2
Kaldas, F.3
Droin, N.4
Luciano, F.5
Ricci, J.E.6
Croxton, R.7
Krajewska, M.8
Zapata, J.M.9
Kupiec-Weglinski, J.W.10
Farmer, D.11
Reed, J.C.12
-
9
-
-
39349083915
-
Adapting proteostasis for disease intervention
-
Balch WE, Morimoto RI, Dillin A, Kelly JW. Adapting proteostasis for disease intervention. Science 319: 916-919, 2008.
-
(2008)
Science
, vol.319
, pp. 916-919
-
-
Balch, W.E.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
-
10
-
-
33845480131
-
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response
-
Bernales S, McDonald KL, Walter P. Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biol 4: e423, 2006.
-
(2006)
PLoS Biol
, vol.4
-
-
Bernales, S.1
McDonald, K.L.2
Walter, P.3
-
11
-
-
79954423426
-
ERAD and ERAD tuning: Disposal of cargo and of ERAD regulators from the mammalian ER
-
Bernasconi R, Molinari M. ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER. Curr Opin Cell Biol 23: 176-183, 2011.
-
(2011)
Curr Opin Cell Biol
, vol.23
, pp. 176-183
-
-
Bernasconi, R.1
Molinari, M.2
-
12
-
-
0035094262
-
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice
-
Bertolotti A, Wang X, Novoa I, Jungreis R, Schlessinger K, Cho JH, West AB, Ron D. Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. J Clin Invest 107: 585-593, 2001.
-
(2001)
J Clin Invest
, vol.107
, pp. 585-593
-
-
Bertolotti, A.1
Wang, X.2
Novoa, I.3
Jungreis, R.4
Schlessinger, K.5
Cho, J.H.6
West, A.B.7
Ron, D.8
-
13
-
-
0033782015
-
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
-
Bertolotti A, Zhang Y, Hendershot LM, Harding HP, Ron D. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol 2: 326-332, 2000.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 326-332
-
-
Bertolotti, A.1
Zhang, Y.2
Hendershot, L.M.3
Harding, H.P.4
Ron, D.5
-
14
-
-
55449127739
-
Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo
-
Bischof LJ, Kao CY, Los FC, Gonzalez MR, Shen Z, Briggs SP, van der Goot FG, Aroian RV. Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo. PLoS Pathog 4: e1000176, 2008.
-
(2008)
PLoS Pathog
, vol.4
-
-
Bischof, L.J.1
Kao, C.Y.2
Los, F.C.3
Gonzalez, M.R.4
Shen, Z.5
Briggs, S.P.6
van der Goot, F.G.7
Aroian, R.V.8
-
15
-
-
4344648874
-
Activating transcription factor 4 is translationally regulated by hypoxic stress
-
Blais JD, Filipenko V, Bi M, Harding HP, Ron D, Koumenis C, Wouters BG, Bell JC. Activating transcription factor 4 is translationally regulated by hypoxic stress. Mol Cell Biol 24: 7469-7482, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7469-7482
-
-
Blais, J.D.1
Filipenko, V.2
Bi, M.3
Harding, H.P.4
Ron, D.5
Koumenis, C.6
Wouters, B.G.7
Bell, J.C.8
-
16
-
-
62549129560
-
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
-
Brandl K, Rutschmann S, Li X, Du X, Xiao N, Schnabl B, Brenner DA, Beutler B. Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response. Proc Natl Acad Sci USA 106: 3300-3305, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3300-3305
-
-
Brandl, K.1
Rutschmann, S.2
Li, X.3
Du, X.4
Xiao, N.5
Schnabl, B.6
Brenner, D.A.7
Beutler, B.8
-
17
-
-
64849113485
-
Control of mitochondrial apoptosis by the Bcl-2 family
-
Brunelle JK, Letai A. Control of mitochondrial apoptosis by the Bcl-2 family. J Cell Sci 122: 437-441, 2009.
-
(2009)
J Cell Sci
, vol.122
, pp. 437-441
-
-
Brunelle, J.K.1
Letai, A.2
-
18
-
-
0037011917
-
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
-
Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, Harding HP, Clark SG, Ron D. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 415: 92-96, 2002.
-
(2002)
Nature
, vol.415
, pp. 92-96
-
-
Calfon, M.1
Zeng, H.2
Urano, F.3
Till, J.H.4
Hubbard, S.R.5
Harding, H.P.6
Clark, S.G.7
Ron, D.8
-
19
-
-
34047136169
-
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis
-
Carrasco DR, Sukhdeo K, Protopopova M, Sinha R, Enos M, Carrasco DE, Zheng M, Mani M, Henderson J, Pinkus GS, Munshi N, Horner J, Ivanova EV, Protopopov A, Anderson KC, Tonon G, DePinho RA. The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis. Cancer Cell 11: 349-360, 2007.
-
(2007)
Cancer Cell
, vol.11
, pp. 349-360
-
-
Carrasco, D.R.1
Sukhdeo, K.2
Protopopova, M.3
Sinha, R.4
Enos, M.5
Carrasco, D.E.6
Zheng, M.7
Mani, M.8
Henderson, J.9
Pinkus, G.S.10
Munshi, N.11
Horner, J.12
Ivanova, E.V.13
Protopopov, A.14
Anderson, K.C.15
Tonon, G.16
Depinho, R.A.17
-
20
-
-
79955508656
-
Attenuation of yeast UPR is essential for survival and is mediated by IRE1 kinase
-
Chawla A, Chakrabarti S, Ghosh G, Niwa M. Attenuation of yeast UPR is essential for survival and is mediated by IRE1 kinase. J Cell Biol 193: 41-50, 2011.
-
(2011)
J Cell Biol
, vol.193
, pp. 41-50
-
-
Chawla, A.1
Chakrabarti, S.2
Ghosh, G.3
Niwa, M.4
-
21
-
-
77954525706
-
SUMO modification regulates the transcriptional activity of XBP1
-
Chen H, Qi L. SUMO modification regulates the transcriptional activity of XBP1. Biochem J 429: 95-102, 2010.
-
(2010)
Biochem J
, vol.429
, pp. 95-102
-
-
Chen, H.1
Qi, L.2
-
22
-
-
0030297537
-
A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response
-
Cox JS, Walter P. A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response. Cell 87: 391-404, 1996.
-
(1996)
Cell
, vol.87
, pp. 391-404
-
-
Cox, J.S.1
Walter, P.2
-
23
-
-
30044432596
-
On the mechanism of sensing unfolded protein in the endoplasmic reticulum
-
Credle JJ, Finer-Moore JS, Papa FR, Stroud RM, Walter P. On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc Natl Acad Sci USA 102: 18773-18784, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18773-18784
-
-
Credle, J.J.1
Finer-Moore, J.S.2
Papa, F.R.3
Stroud, R.M.4
Walter, P.5
-
24
-
-
72649087136
-
Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liver
-
Cretenet G, Le Clech M, Gachon F. Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liver. Cell Metab 11: 47-57, 2010.
-
(2010)
Cell Metab
, vol.11
, pp. 47-57
-
-
Cretenet, G.1
le Clech, M.2
Gachon, F.3
-
25
-
-
34250880766
-
The inositol trisphosphate receptor in the control of autophagy
-
Criollo A, Vicencio JM, Tasdemir E, Maiuri MC, Lavandero S, Kroemer G. The inositol trisphosphate receptor in the control of autophagy. Autophagy 3: 350-353, 2007.
-
(2007)
Autophagy
, vol.3
, pp. 350-353
-
-
Criollo, A.1
Vicencio, J.M.2
Tasdemir, E.3
Maiuri, M.C.4
Lavandero, S.5
Kroemer, G.6
-
26
-
-
2442542312
-
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
-
Cullinan SB, Diehl JA. PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. J Biol Chem 279: 20108-20117, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 20108-20117
-
-
Cullinan, S.B.1
Diehl, J.A.2
-
27
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
Cullinan SB, Zhang D, Hannink M, Arvisais E, Kaufman RJ, Diehl JA. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol Cell Biol 23: 7198-7209, 2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
28
-
-
0842281645
-
Cell death: Critical control points
-
Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 116: 205-219, 2004.
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
29
-
-
69449086287
-
HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats
-
Delay ML, Turner MJ, Klenk EI, Smith JA, Sowders DP, Colbert RA. HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats. Arthritis Rheum 60: 2633-2643, 2009.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2633-2643
-
-
Delay, M.L.1
Turner, M.J.2
Klenk, E.I.3
Smith, J.A.4
Sowders, D.P.5
Colbert, R.A.6
-
30
-
-
0034425698
-
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome
-
Delépine M, Nicolino M, Barrett T, Golamaully M, Lathrop GM, Julier C. EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome. Nature Genet 25: 406-409, 2000.
-
(2000)
Nature Genet
, vol.25
, pp. 406-409
-
-
Delépine, M.1
Nicolino, M.2
Barrett, T.3
Golamaully, M.4
Lathrop, G.M.5
Julier, C.6
-
31
-
-
62749115187
-
Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress
-
Delibegovic M, Zimmer D, Kauffman C, Rak K, Hong EG, Cho YR, Kim JK, Kahn BB, Neel BG, Bence KK. Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress. Diabetes 58: 590-599, 2009.
-
(2009)
Diabetes
, vol.58
, pp. 590-599
-
-
Delibegovic, M.1
Zimmer, D.2
Kauffman, C.3
Rak, K.4
Hong, E.G.5
Cho, Y.R.6
Kim, J.K.7
Kahn, B.B.8
Neel, B.G.9
Bence, K.K.10
-
32
-
-
67549092262
-
XBP-1 interacts with estrogen receptor alpha (ERalpha)
-
Ding LH, Ye QN, Yan JH, Zhu JH, Lu QJ, Wang ZH, Huang CF. XBP-1 interacts with estrogen receptor alpha (ERalpha). ShengWuGong Cheng Xue Bao 20: 332-336, 2004.
-
(2004)
ShengWuGong Cheng Xue Bao
, vol.20
, pp. 332-336
-
-
Ding, L.H.1
Ye, Q.N.2
Yan, J.H.3
Zhu, J.H.4
Lu, Q.J.5
Wang, Z.H.6
Huang, C.F.7
-
33
-
-
34548299555
-
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
-
Ding WX, Ni HM, Gao W, Yoshimori T, Stolz DB, Ron D, Yin XM. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol 171: 513-524, 2007.
-
(2007)
Am J Pathol
, vol.171
, pp. 513-524
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
Yoshimori, T.4
Stolz, D.B.5
Ron, D.6
Yin, X.M.7
-
34
-
-
0037336295
-
Quality control in the endoplasmic reticulum
-
Ellgaard L, Helenius A. Quality control in the endoplasmic reticulum. Nat Rev Mol Cell Biol 4: 181-191, 2003.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 181-191
-
-
Ellgaard, L.1
Helenius, A.2
-
35
-
-
0035736259
-
Organelle-specific initiation of cell death pathways
-
Ferri KF, Kroemer G. Organelle-specific initiation of cell death pathways. Nat Cell Biol 3: E255-263, 2001.
-
(2001)
Nat Cell Biol
, vol.3
-
-
Ferri, K.F.1
Kroemer, G.2
-
36
-
-
78650412221
-
Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA
-
Galehdar Z, Swan P, Fuerth B, Callaghan SM, Park DS, Cregan SP. Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA. J Neurosci 30: 16938-16948, 2010.
-
(2010)
J Neurosci
, vol.30
, pp. 16938-16948
-
-
Galehdar, Z.1
Swan, P.2
Fuerth, B.3
Callaghan, S.M.4
Park, D.S.5
Cregan, S.P.6
-
37
-
-
70350459324
-
From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis
-
Glimcher LH, Lee AH. From sugar to fat: how the transcription factor XBP1 regulates hepatic lipogenesis. Ann NY Acad Sci 1173 Suppl 1: E2-9, 2009.
-
(2009)
Ann NY Acad Sci
, vol.1173
, Issue.SUPPL. 1
-
-
Glimcher, L.H.1
Lee, A.H.2
-
38
-
-
9644303176
-
Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress
-
Gu F, Nguyen DT, Stuible M, Dube N, Tremblay ML, Chevet E. Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress. J Biol Chem 279: 49689-49693, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 49689-49693
-
-
Gu, F.1
Nguyen, D.T.2
Stuible, M.3
Dube, N.4
Tremblay, M.L.5
Chevet, E.6
-
39
-
-
77955044180
-
HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction
-
Gupta S, Deepti A, Deegan S, Lisbona F, Hetz C, Samali A. HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction. PLoS Biol 8: e1000410, 2010.
-
(2010)
PLoS Biol
, vol.8
-
-
Gupta, S.1
Deepti, A.2
Deegan, S.3
Lisbona, F.4
Hetz, C.5
Samali, A.6
-
40
-
-
0032549767
-
BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation
-
Hamman BD, Hendershot LM, Johnson AE. BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation. Cell 92: 747-758, 1998.
-
(1998)
Cell
, vol.92
, pp. 747-758
-
-
Hamman, B.D.1
Hendershot, L.M.2
Johnson, A.E.3
-
41
-
-
68049110633
-
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates
-
Han D, Lerner AG, Vande Walle L, Upton JP, Xu W, Hagen A, Backes BJ, Oakes SA, Papa FR. IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. Cell 138: 562-575, 2009.
-
(2009)
Cell
, vol.138
, pp. 562-575
-
-
Han, D.1
Lerner, A.G.2
Vande Walle, L.3
Upton, J.P.4
Xu, W.5
Hagen, A.6
Backes, B.J.7
Oakes, S.A.8
Papa, F.R.9
-
42
-
-
0034968330
-
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/-mice reveals a role for translational control in secretory cell survival
-
Harding HP, Zeng H, Zhang Y, Jungries R, Chung P, Plesken H, Sabatini DD, Ron D. Diabetes mellitus and exocrine pancreatic dysfunction in perk-/-mice reveals a role for translational control in secretory cell survival. Mol Cell 7: 1153-1163, 2001.
-
(2001)
Mol Cell
, vol.7
, pp. 1153-1163
-
-
Harding, H.P.1
Zeng, H.2
Zhang, Y.3
Jungries, R.4
Chung, P.5
Plesken, H.6
Sabatini, D.D.7
Ron, D.8
-
43
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
Harding HP, Zhang Y, Zeng H, Novoa I, Lu PD, Calfon M, Sadri N, Yun C, Popko B, Paules R, Stojdl DF, Bell JC, Hettmann T, Leiden JM, Ron D. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol Cell 11: 619-633, 2003.
-
(2003)
Mol Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
Sadri, N.7
Yun, C.8
Popko, B.9
Paules, R.10
Stojdl, D.F.11
Bell, J.C.12
Hettmann, T.13
Leiden, J.M.14
Ron, D.15
-
44
-
-
53449098260
-
Attenuated BDNF-induced upregulation of GABAergic markers in neurons lacking Xbp1
-
Hayashi A, Kasahara T, Kametani M, Kato T. Attenuated BDNF-induced upregulation of GABAergic markers in neurons lacking Xbp1. Biochem Biophys Res Commun 376: 758-763, 2008.
-
(2008)
Biochem Biophys Res Commun
, vol.376
, pp. 758-763
-
-
Hayashi, A.1
Kasahara, T.2
Kametani, M.3
Kato, T.4
-
45
-
-
0032693671
-
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
-
Haze K, Yoshida H, Yanagi H, Yura T, Mori K. Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol Biol Cell 10: 3787-3799, 1999.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 3787-3799
-
-
Haze, K.1
Yoshida, H.2
Yanagi, H.3
Yura, T.4
Mori, K.5
-
46
-
-
72549095406
-
Regulation mechanisms and signaling pathways of autophagy
-
He C, Klionsky DJ. Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet 43: 67-93, 2009.
-
(2009)
Annu Rev Genet
, vol.43
, pp. 67-93
-
-
He, C.1
Klionsky, D.J.2
-
47
-
-
0035877643
-
Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation
-
He CH, Gong P, Hu B, Stewart D, Choi ME, Choi AM, Alam J. Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation. J Biol Chem 276: 20858-20865, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 20858-20865
-
-
He, C.H.1
Gong, P.2
Hu, B.3
Stewart, D.4
Choi, M.E.5
Choi, A.M.6
Alam, J.7
-
48
-
-
71749110928
-
Targeting the endoplasmic reticulum-stress response as an anticancer strategy
-
Healy SJM, Gorman AM, Mousavi-Shafaei P, Gupta S, Samali A. Targeting the endoplasmic reticulum-stress response as an anticancer strategy. Eur J Pharmacol 625: 234-246, 2009.
-
(2009)
Eur J Pharmacol
, vol.625
, pp. 234-246
-
-
Healy, S.J.M.1
Gorman, A.M.2
Mousavi-Shafaei, P.3
Gupta, S.4
Samali, A.5
-
49
-
-
35748948975
-
In and out of the ER: Protein folding, quality control, degradation, and related human diseases
-
Hebert DN, Molinari M. In and out of the ER: protein folding, quality control, degradation, and related human diseases. Physiol Rev 87: 1377-1408, 2007.
-
(2007)
Physiol Rev
, vol.87
, pp. 1377-1408
-
-
Hebert, D.N.1
Molinari, M.2
-
50
-
-
33646237823
-
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha
-
Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt GS, Iwakoshi NN, Schinzel A, Glimcher LH, Korsmeyer SJ. Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha. Science 312: 572-576, 2006.
-
(2006)
Science
, vol.312
, pp. 572-576
-
-
Hetz, C.1
Bernasconi, P.2
Fisher, J.3
Lee, A.H.4
Bassik, M.C.5
Antonsson, B.6
Brandt, G.S.7
Iwakoshi, N.N.8
Schinzel, A.9
Glimcher, L.H.10
Korsmeyer, S.J.11
-
51
-
-
69749123786
-
Fine-tuning of the unfolded protein response: Assembling the IRE1 α interactome
-
Hetz C, Glimcher LH. Fine-tuning of the unfolded protein response: assembling the IRE1 α interactome. Mol Cell 35: 551-561, 2009.
-
(2009)
Mol Cell
, vol.35
, pp. 551-561
-
-
Hetz, C.1
Glimcher, L.H.2
-
52
-
-
41649114777
-
The UPRosome and XBP-1: Mastering secretory cell function
-
Hetz C, Glimcher LH. The UPRosome and XBP-1: mastering secretory cell function. Curr Immunol Rev 4: 1-10, 2008.
-
(2008)
Curr Immunol Rev
, vol.4
, pp. 1-10
-
-
Hetz, C.1
Glimcher, L.H.2
-
53
-
-
38649108109
-
Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis
-
Hetz C, Lee AH, Gonzalez-Romero D, Thielen P, Castilla J, Soto C, Glimcher LH. Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. Proc Natl Acad Sci USA 105: 757-762, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 757-762
-
-
Hetz, C.1
Lee, A.H.2
Gonzalez-Romero, D.3
Thielen, P.4
Castilla, J.5
Soto, C.6
Glimcher, L.H.7
-
54
-
-
70349627027
-
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
-
Hetz C, Thielen P, Matus S, Nassif M, Court F, Kiffin R, Martinez G, Cuervo AM, Brown RH, Glimcher LH. XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes Dev 23: 2294-2306, 2009.
-
(2009)
Genes Dev
, vol.23
, pp. 2294-2306
-
-
Hetz, C.1
Thielen, P.2
Matus, S.3
Nassif, M.4
Court, F.5
Kiffin, R.6
Martinez, G.7
Cuervo, A.M.8
Brown, R.H.9
Glimcher, L.H.10
-
55
-
-
68549092781
-
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
-
Hollien J, Lin JH, Li H, Stevens N, Walter P, Weissman JS. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol 186: 323-331, 2009.
-
(2009)
J Cell Biol
, vol.186
, pp. 323-331
-
-
Hollien, J.1
Lin, J.H.2
Li, H.3
Stevens, N.4
Walter, P.5
Weissman, J.S.6
-
56
-
-
33745893809
-
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
-
Hollien J, Weissman JS. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 313: 104-107, 2006.
-
(2006)
Science
, vol.313
, pp. 104-107
-
-
Hollien, J.1
Weissman, J.S.2
-
57
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140: 900-917, 2010.
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
58
-
-
67349176043
-
XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells
-
Hu CC, Dougan SK, McGehee AM, Love JC, Ploegh HL. XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells. EMBO J 28: 1624-1636, 2009.
-
(2009)
EMBO J
, vol.28
, pp. 1624-1636
-
-
Hu, C.C.1
Dougan, S.K.2
McGehee, A.M.3
Love, J.C.4
Ploegh, H.L.5
-
59
-
-
33645815074
-
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression
-
Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH. Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. Mol Cell Biol 26: 3071-3084, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3071-3084
-
-
Hu, P.1
Han, Z.2
Couvillon, A.D.3
Kaufman, R.J.4
Exton, J.H.5
-
60
-
-
78649688693
-
XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum
-
Huh WJ, Esen E, Geahlen JH, Bredemeyer AJ, Lee AH, Shi G, Konieczny SF, Glimcher LH, Mills JC. XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum. Gastroenterology 139: 2038-2049, 2011.
-
(2011)
Gastroenterology
, vol.139
, pp. 2038-2049
-
-
Huh, W.J.1
Esen, E.2
Geahlen, J.H.3
Bredemeyer, A.J.4
Lee, A.H.5
Shi, G.6
Konieczny, S.F.7
Glimcher, L.H.8
Mills, J.C.9
-
61
-
-
68649100255
-
The proteostasis boundary in misfolding diseases of membrane traffic
-
Hutt DM, Powers ET, Balch WE. The proteostasis boundary in misfolding diseases of membrane traffic. FEBS Lett 583: 2639-2646, 2009.
-
(2009)
FEBS Lett
, vol.583
, pp. 2639-2646
-
-
Hutt, D.M.1
Powers, E.T.2
Balch, W.E.3
-
62
-
-
58849138276
-
Seipinopathy: A novel endoplasmic reticulum stress-associated disease
-
Ito D, Suzuki N. Seipinopathy: a novel endoplasmic reticulum stress-associated disease. Brain 132: 8-15, 2009.
-
(2009)
Brain
, vol.132
, pp. 8-15
-
-
Ito, D.1
Suzuki, N.2
-
63
-
-
0037385313
-
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
-
Iwakoshi NN, Lee AH, Vallabhajosyula P, Otipoby KL, Rajewsky K, Glimcher LH. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat Immunol 4: 321-329, 2003.
-
(2003)
Nat Immunol
, vol.4
, pp. 321-329
-
-
Iwakoshi, N.N.1
Lee, A.H.2
Vallabhajosyula, P.3
Otipoby, K.L.4
Rajewsky, K.5
Glimcher, L.H.6
-
64
-
-
34948897411
-
The transcription factor XBP-1 is essential for the development and survival of dendritic cells
-
Iwakoshi NN, Pypaert M, Glimcher LH. The transcription factor XBP-1 is essential for the development and survival of dendritic cells. J Exp Med 204: 2267-2275, 2007.
-
(2007)
J Exp Med
, vol.204
, pp. 2267-2275
-
-
Iwakoshi, N.N.1
Pypaert, M.2
Glimcher, L.H.3
-
65
-
-
77958590030
-
IRE1alpha disruption causes histological abnormality of exocrine tissues, increase of blood glucose level, and decrease of serum immunoglobulin level
-
Iwawaki T, Akai R, Kohno K. IRE1alpha disruption causes histological abnormality of exocrine tissues, increase of blood glucose level, and decrease of serum immunoglobulin level. PLoS One 5: e13052, 2010.
-
(2010)
PLoS One
, vol.5
-
-
Iwawaki, T.1
Akai, R.2
Kohno, K.3
-
66
-
-
70349756962
-
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
-
Iwawaki T, Akai R, Yamanaka S, Kohno K. Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability. Proc Natl Acad Sci USA 106: 16657-16662, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16657-16662
-
-
Iwawaki, T.1
Akai, R.2
Yamanaka, S.3
Kohno, K.4
-
67
-
-
0037312881
-
Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse
-
Izumi T, Yokota-Hashimoto H, Zhao S, Wang J, Halban PA, Takeuchi T. Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse. Diabetes 52: 409-416, 2003.
-
(2003)
Diabetes
, vol.52
, pp. 409-416
-
-
Izumi, T.1
Yokota-Hashimoto, H.2
Zhao, S.3
Wang, J.4
Halban, P.A.5
Takeuchi, T.6
-
68
-
-
33645280897
-
XBP1 induces WFS1 through an endoplasmic reticulum stress response element-like motif in SH-SY5Y cells
-
Kakiuchi C, Ishiwata M, Hayashi A, Kato T. XBP1 induces WFS1 through an endoplasmic reticulum stress response element-like motif in SH-SY5Y cells. J Neurochem 97: 545-555, 2006.
-
(2006)
J Neurochem
, vol.97
, pp. 545-555
-
-
Kakiuchi, C.1
Ishiwata, M.2
Hayashi, A.3
Kato, T.4
-
69
-
-
3843051149
-
Regulatory roles of JNK in programmed cell death
-
Kanda H, Miura M. Regulatory roles of JNK in programmed cell death. J Biochem 136: 1-6, 2004.
-
(2004)
J Biochem
, vol.136
, pp. 1-6
-
-
Kanda, H.1
Miura, M.2
-
70
-
-
50249086073
-
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
-
Kaser A, Lee AH, Franke A, Glickman JN, Zeissig S, Tilg H, Nieuwenhuis EE, Higgins DE, Schreiber S, Glimcher LH, Blumberg RS. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell 134: 743-756, 2008.
-
(2008)
Cell
, vol.134
, pp. 743-756
-
-
Kaser, A.1
Lee, A.H.2
Franke, A.3
Glickman, J.N.4
Zeissig, S.5
Tilg, H.6
Nieuwenhuis, E.E.7
Higgins, D.E.8
Schreiber, S.9
Glimcher, L.H.10
Blumberg, R.S.11
-
71
-
-
77954144700
-
Endoplasmic reticulum stress: Implications for inflammatory bowel disease pathogenesis
-
Kaser A, Martínez-Naves E, Blumberg RS. Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesis. Curr Opin Gastroenterol 26: 318-326, 2010.
-
(2010)
Curr Opin Gastroenterol
, vol.26
, pp. 318-326
-
-
Kaser, A.1
Martínez-Naves, E.2
Blumberg, R.S.3
-
72
-
-
1542316306
-
Regulation of mRNA translation by protein folding in the endoplasmic reticulum
-
Kaufman RJ. Regulation of mRNA translation by protein folding in the endoplasmic reticulum. Trends Biochem Sci 29: 152-158, 2004.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 152-158
-
-
Kaufman, R.J.1
-
73
-
-
0036677435
-
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease
-
Keene CD, Rodrigues CM, Eich T, Chhabra MS, Steer CJ, Low WC. Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease. Proc Natl Acad Sci USA 99: 10671-10676, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10671-10676
-
-
Keene, C.D.1
Rodrigues, C.M.2
Eich, T.3
Chhabra, M.S.4
Steer, C.J.5
Low, W.C.6
-
74
-
-
70449091753
-
Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis
-
Kim H, Tu HC, Ren D, Takeuchi O, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH. Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. Mol Cell 36: 487-499, 2009.
-
(2009)
Mol Cell
, vol.36
, pp. 487-499
-
-
Kim, H.1
Tu, H.C.2
Ren, D.3
Takeuchi, O.4
Jeffers, J.R.5
Zambetti, G.P.6
Hsieh, J.J.7
Cheng, E.H.8
-
75
-
-
35348967427
-
Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins
-
Kimata Y, Ishiwata-Kimata Y, Ito T, Hirata A, Suzuki T, Oikawa D, Takeuchi M, Kohno K. Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins. J Cell Biol 179: 75-86, 2007.
-
(2007)
J Cell Biol
, vol.179
, pp. 75-86
-
-
Kimata, Y.1
Ishiwata-Kimata, Y.2
Ito, T.3
Hirata, A.4
Suzuki, T.5
Oikawa, D.6
Takeuchi, M.7
Kohno, K.8
-
76
-
-
0038308388
-
Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins
-
Kimata Y, Kimata YI, Shimizu Y, Abe H, Farcasanu IC, Takeuchi M, Rose MD, Kohno K. Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins. Mol Biol Cell 14: 2559-2569, 2003.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 2559-2569
-
-
Kimata, Y.1
Kimata, Y.I.2
Shimizu, Y.3
Abe, H.4
Farcasanu, I.C.5
Takeuchi, M.6
Rose, M.D.7
Kohno, K.8
-
77
-
-
8444250981
-
A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1
-
Kimata Y, Oikawa D, Shimizu Y, Ishiwata-Kimata Y, Kohno K. A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1. J Cell Biol 167: 445-456, 2004.
-
(2004)
J Cell Biol
, vol.167
, pp. 445-456
-
-
Kimata, Y.1
Oikawa, D.2
Shimizu, Y.3
Ishiwata-Kimata, Y.4
Kohno, K.5
-
78
-
-
67649547153
-
Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak
-
Klee M, Pallauf K, Alcala S, Fleischer A, Pimentel-Muinos FX. Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak. EMBO J 28: 1757-1768, 2009.
-
(2009)
EMBO J
, vol.28
, pp. 1757-1768
-
-
Klee, M.1
Pallauf, K.2
Alcala, S.3
Fleischer, A.4
Pimentel-Muinos, F.X.5
-
79
-
-
13944263299
-
OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes
-
Kondo S, Murakami T, Tatsumi K, Ogata M, Kanemoto S, Otori K, Iseki K, Wanaka A, Imaizumi K. OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes. Nat Cell Biol 7: 186-194, 2005.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 186-194
-
-
Kondo, S.1
Murakami, T.2
Tatsumi, K.3
Ogata, M.4
Kanemoto, S.5
Otori, K.6
Iseki, K.7
Wanaka, A.8
Imaizumi, K.9
-
80
-
-
33847188475
-
BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer
-
Kondo S, Saito A, Hino S, Murakami T, Ogata M, Kanemoto S, Nara S, Yamashita A, Yoshinaga K, Hara H, Imaizumi K. BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer. Mol Cell Biol 27: 1716-1729, 2007.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1716-1729
-
-
Kondo, S.1
Saito, A.2
Hino, S.3
Murakami, T.4
Ogata, M.5
Kanemoto, S.6
Nara, S.7
Yamashita, A.8
Yoshinaga, K.9
Hara, H.10
Imaizumi, K.11
-
82
-
-
59649111087
-
The unfolded protein response signals through high-order assembly of Ire1
-
Korennykh AV, Egea PF, Korostelev AA, Finer-Moore J, Zhang C, Shokat KM, Stroud RM, Walter P. The unfolded protein response signals through high-order assembly of Ire1. Nature 457: 687-693, 2009.
-
(2009)
Nature
, vol.457
, pp. 687-693
-
-
Korennykh, A.V.1
Egea, P.F.2
Korostelev, A.A.3
Finer-Moore, J.4
Zhang, C.5
Shokat, K.M.6
Stroud, R.M.7
Walter, P.8
-
83
-
-
33646167400
-
ER stress, hypoxia tolerance and tumor progression
-
Koumenis C. ER stress, hypoxia tolerance and tumor progression. Curr Mol Med 6: 55-69, 2006.
-
(2006)
Curr Mol Med
, vol.6
, pp. 55-69
-
-
Koumenis, C.1
-
84
-
-
78651364538
-
Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury
-
Krajewska M, Xu L, Xu W, Krajewski S, Kress CL, Cui J, Yang L, Irie F, Yamaguchi Y, Lipton SA, Reed JC. Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury. Brain Res 1370: 227-237, 2011.
-
(2011)
Brain Res
, vol.1370
, pp. 227-237
-
-
Krajewska, M.1
Xu, L.2
Xu, W.3
Krajewski, S.4
Kress, C.L.5
Cui, J.6
Yang, L.7
Irie, F.8
Yamaguchi, Y.9
Lipton, S.A.10
Reed, J.C.11
-
85
-
-
78649338141
-
Autophagy and the integrated stress response
-
Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 40: 280-293, 2010.
-
(2010)
Mol Cell
, vol.40
, pp. 280-293
-
-
Kroemer, G.1
Marino, G.2
Levine, B.3
-
86
-
-
42449154243
-
XBP-1, a novel human T-lymphotropic virus type 1 (HTLV-1) tax binding protein, activates HTLV-1 basal and tax-activated transcription
-
Ku SC, Lee J, Lau J, Gurumurthy M, Ng R, Lwa SH, Lee J, Klase Z, Kashanchi F, Chao SH. XBP-1, a novel human T-lymphotropic virus type 1 (HTLV-1) tax binding protein, activates HTLV-1 basal and tax-activated transcription. J Virol 82: 4343-4353, 2008.
-
(2008)
J Virol
, vol.82
, pp. 4343-4353
-
-
Ku, S.C.1
Lee, J.2
Lau, J.3
Gurumurthy, M.4
Ng, R.5
Lwa, S.H.6
Lee, J.7
Klase, Z.8
Kashanchi, F.9
Chao, S.H.10
-
87
-
-
20144386666
-
Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK
-
Ladiges WC, Knoblaugh SE, Morton JF, Korth MJ, Sopher BL, Baskin CR, MacAuley A, Goodman AG, LeBoeuf RC, Katze MG. Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK. Diabetes 54: 1074-1081, 2005.
-
(2005)
Diabetes
, vol.54
, pp. 1074-1081
-
-
Ladiges, W.C.1
Knoblaugh, S.E.2
Morton, J.F.3
Korth, M.J.4
Sopher, B.L.5
Baskin, C.R.6
Macauley, A.7
Goodman, A.G.8
Leboeuf, R.C.9
Katze, M.G.10
-
88
-
-
29244448729
-
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands
-
Lee AH, Chu GC, Iwakoshi NN, Glimcher LH. XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. EMBO J 24: 4368-4380, 2005.
-
(2005)
EMBO J
, vol.24
, pp. 4368-4380
-
-
Lee, A.H.1
Chu, G.C.2
Iwakoshi, N.N.3
Glimcher, L.H.4
-
89
-
-
45849137877
-
Regulation of hepatic lipogenesis by the transcription factor XBP1
-
Lee AH, Scapa E, Cohen D, Glimcher L. Regulation of hepatic lipogenesis by the transcription factor XBP1. Science 320: 1492, 2008.
-
(2008)
Science
, vol.320
, pp. 1492
-
-
Lee, A.H.1
Scapa, E.2
Cohen, D.3
Glimcher, L.4
-
90
-
-
29244448729
-
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands
-
Lee AH, Chu GC, Iwakoshi NN, Glimcher LH. XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. EMBO J 24: 4368-4380, 2005.
-
(2005)
EMBO J
, vol.24
, pp. 4368-4380
-
-
Lee, A.H.1
Chu, G.C.2
Iwakoshi, N.N.3
Glimcher, L.H.4
-
91
-
-
0142059951
-
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
-
Lee AH, Iwakoshi NN, Glimcher LH. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol Cell Biol 23: 7448-7459, 2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7448-7459
-
-
Lee, A.H.1
Iwakoshi, N.N.2
Glimcher, L.H.3
-
92
-
-
0037083755
-
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
-
Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev 16: 452-466, 2002.
-
(2002)
Genes Dev
, vol.16
, pp. 452-466
-
-
Lee, K.1
Tirasophon, W.2
Shen, X.3
Michalak, M.4
Prywes, R.5
Okada, T.6
Yoshida, H.7
Mori, K.8
Kaufman, R.J.9
-
93
-
-
37649004940
-
Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing
-
Lee KP, Dey M, Neculai D, Cao C, Dever TE, Sicheri F. Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing. Cell 132: 89-100, 2008.
-
(2008)
Cell
, vol.132
, pp. 89-100
-
-
Lee, K.P.1
Dey, M.2
Neculai, D.3
Cao, C.4
Dever, T.E.5
Sicheri, F.6
-
94
-
-
77958016968
-
Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering
-
Li H, Korennykh AV, Behrman SL, Walter P. Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering. Proc Natl Acad Sci USA 107: 16113-16118, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 16113-16118
-
-
Li, H.1
Korennykh, A.V.2
Behrman, S.L.3
Walter, P.4
-
95
-
-
33646373219
-
Endoplasmic reticulum stress-induced apoptosis: Multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53
-
Li J, Lee B, Lee AS. Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53. J Biol Chem 281: 7260-7270, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 7260-7270
-
-
Li, J.1
Lee, B.2
Lee, A.S.3
-
96
-
-
33750350899
-
Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element
-
Liang G, Audas TE, Li Y, Cockram GP, Dean JD, Martyn AC, Kokame K, Lu R. Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element. Mol Cell Biol 26: 7999-8010, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7999-8010
-
-
Liang, G.1
Audas, T.E.2
Li, Y.3
Cockram, G.P.4
Dean, J.D.5
Martyn, A.C.6
Kokame, K.7
Lu, R.8
-
97
-
-
36049049392
-
IRE1 signaling affects cell fate during the unfolded protein response
-
Lin JH, Li H, Yasumura D, Cohen HR, Zhang C, Panning B, Shokat KM, Lavail MM, Walter P. IRE1 signaling affects cell fate during the unfolded protein response. Science 318: 944-949, 2007.
-
(2007)
Science
, vol.318
, pp. 944-949
-
-
Lin, J.H.1
Li, H.2
Yasumura, D.3
Cohen, H.R.4
Zhang, C.5
Panning, B.6
Shokat, K.M.7
Lavail, M.M.8
Walter, P.9
-
98
-
-
58449084895
-
Divergent effects of PERK and IRE1 signaling on cell viability
-
Lin JH, Li H, Zhang Y, Ron D, Walter P. Divergent effects of PERK and IRE1 signaling on cell viability. PLoS One 4: e4170, 2009.
-
(2009)
PLoS One
, vol.4
-
-
Lin, J.H.1
Li, H.2
Zhang, Y.3
Ron, D.4
Walter, P.5
-
100
-
-
33747849846
-
Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulumresident protein kinase IRE1
-
Lipson KL, Fonseca SG, Ishigaki S, Nguyen LX, Foss E, Bortell R, Rossini AA, Urano F. Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulumresident protein kinase IRE1. Cell Metab 4: 245-254, 2006.
-
(2006)
Cell Metab
, vol.4
, pp. 245-254
-
-
Lipson, K.L.1
Fonseca, S.G.2
Ishigaki, S.3
Nguyen, L.X.4
Foss, E.5
Bortell, R.6
Rossini, A.A.7
Urano, F.8
-
101
-
-
33646166752
-
Endoplasmic reticulum stress-induced apoptosis and auto-immunity in diabetes
-
Lipson KL, Fonseca SG, Urano F. Endoplasmic reticulum stress-induced apoptosis and auto-immunity in diabetes. Curr Mol Med 6: 71-77, 2006.
-
(2006)
Curr Mol Med
, vol.6
, pp. 71-77
-
-
Lipson, K.L.1
Fonseca, S.G.2
Urano, F.3
-
102
-
-
45749114525
-
The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells
-
Lipson KL, Ghosh R, Urano F. The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells. PLoS ONE 3: e1648, 2008.
-
(2008)
PLoS ONE
, vol.3
-
-
Lipson, K.L.1
Ghosh, R.2
Urano, F.3
-
103
-
-
66749147692
-
Turning off the unfolded protein response: An interplay between the apoptosis machinery and ER stress signaling
-
Lisbona F, Hetz C. Turning off the unfolded protein response: an interplay between the apoptosis machinery and ER stress signaling. Cell Cycle 8: 1643-1644, 2009.
-
(2009)
Cell Cycle
, vol.8
, pp. 1643-1644
-
-
Lisbona, F.1
Hetz, C.2
-
104
-
-
62549129467
-
BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha
-
Lisbona F, Rojas-Rivera D, Thielen P, Zamorano S, Todd D, Martinon F, Glavic A, Kress C, Lin JH, Walter P, Reed JC, Glimcher LH, Hetz C. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Mol Cell 33: 679-691, 2009.
-
(2009)
Mol Cell
, vol.33
, pp. 679-691
-
-
Lisbona, F.1
Rojas-Rivera, D.2
Thielen, P.3
Zamorano, S.4
Todd, D.5
Martinon, F.6
Glavic, A.7
Kress, C.8
Lin, J.H.9
Walter, P.10
Reed, J.C.11
Glimcher, L.H.12
Hetz, C.13
-
105
-
-
0034637605
-
Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum
-
Liu CY, Schroder M, Kaufman RJ. Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum. J Biol Chem 275: 24881-24885, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 24881-24885
-
-
Liu, C.Y.1
Schroder, M.2
Kaufman, R.J.3
-
106
-
-
45549103421
-
AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response
-
Luo D, He Y, Zhang H, Yu L, Chen H, Xu Z, Tang S, Urano F, Min W. AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response. J Biol Chem 283: 11905-11912, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 11905-11912
-
-
Luo, D.1
He, Y.2
Zhang, H.3
Yu, L.4
Chen, H.5
Xu, Z.6
Tang, S.7
Urano, F.8
Min, W.9
-
107
-
-
10344222124
-
The role of the unfolded protein response in tumour development: Friend or foe?
-
Ma Y, Hendershot LM. The role of the unfolded protein response in tumour development: friend or foe? Nat Rev Cancer 4: 966-977, 2004.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 966-977
-
-
Ma, Y.1
Hendershot, L.M.2
-
108
-
-
34548188741
-
Self-eating and self-killing: Crosstalk between autophagy and apoptosis
-
Maiuri MC, Zalckvar E, Kimchi A, Kroemer G. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8: 741-752, 2007.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 741-752
-
-
Maiuri, M.C.1
Zalckvar, E.2
Kimchi, A.3
Kroemer, G.4
-
109
-
-
35848957485
-
Endoplasmic reticulum stress and oxidative stress: A vicious cycle or a double-edged sword?
-
Malhotra JD, Kaufman RJ. Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword? Antioxid Redox Signal 9: 2277-2293, 2007.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 2277-2293
-
-
Malhotra, J.D.1
Kaufman, R.J.2
-
110
-
-
10644233167
-
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
-
Marciniak SJ, Yun CY, Oyadomari S, Novoa I, Zhang Y, Jungreis R, Nagata K, Harding HP, Ron D. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev 18: 3066-3077, 2004.
-
(2004)
Genes Dev
, vol.18
, pp. 3066-3077
-
-
Marciniak, S.J.1
Yun, C.Y.2
Oyadomari, S.3
Novoa, I.4
Zhang, Y.5
Jungreis, R.6
Nagata, K.7
Harding, H.P.8
Ron, D.9
-
111
-
-
18744382408
-
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha
-
Marcu MG, Doyle M, Bertolotti A, Ron D, Hendershot L, Neckers L. Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha. Mol Cell Biol 22: 8506-8513, 2002.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8506-8513
-
-
Marcu, M.G.1
Doyle, M.2
Bertolotti, A.3
Ron, D.4
Hendershot, L.5
Neckers, L.6
-
112
-
-
77951290227
-
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
-
Martinon F, Chen X, Lee AH, Glimcher LH. TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nature Immunol 11: 411-418, 2010.
-
(2010)
Nature Immunol
, vol.11
, pp. 411-418
-
-
Martinon, F.1
Chen, X.2
Lee, A.H.3
Glimcher, L.H.4
-
113
-
-
79954425809
-
Protein folding stress in neurodegenerative diseases: A glimpse into the ER
-
Matus S, Glimcher LH, Hetz C. Protein folding stress in neurodegenerative diseases: a glimpse into the ER. Curr Opin Cell Biol 23: 239-252, 2011.
-
(2011)
Curr Opin Cell Biol
, vol.23
, pp. 239-252
-
-
Matus, S.1
Glimcher, L.H.2
Hetz, C.3
-
114
-
-
45549091524
-
The stress rheostat: An interplay between the unfolded protein response (UPR) and autophagy in neurodegeneration
-
Matus S, Lisbona F, Torres M, León C, Thielen P, Hetz C. The stress rheostat: an interplay between the unfolded protein response (UPR) and autophagy in neurodegeneration. Curr Mol Med 8: 157-172, 2008.
-
(2008)
Curr Mol Med
, vol.8
, pp. 157-172
-
-
Matus, S.1
Lisbona, F.2
Torres, M.3
León, C.4
Thielen, P.5
Hetz, C.6
-
115
-
-
73449097110
-
XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy
-
Matus S, Nassif M, Glimcher LH, Hetz C. XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy. Autophagy 5: 1226-1228, 2009.
-
(2009)
Autophagy
, vol.5
, pp. 1226-1228
-
-
Matus, S.1
Nassif, M.2
Glimcher, L.H.3
Hetz, C.4
-
116
-
-
33646365640
-
Central role of the scaffold protein tumor necrosis factor receptor-associated factor 2 in regulating endoplasmic reticulum stress-induced apoptosis
-
Mauro C, Crescenzi E, De Mattia R, Pacifico F, Mellone S, Salzano S, de Luca C, D'Adamio L, Palumbo G, Formisano S, Vito P, Leonardi A. Central role of the scaffold protein tumor necrosis factor receptor-associated factor 2 in regulating endoplasmic reticulum stress-induced apoptosis. J Biol Chem 281: 2631-2638, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 2631-2638
-
-
Mauro, C.1
Crescenzi, E.2
de Mattia, R.3
Pacifico, F.4
Mellone, S.5
Salzano, S.6
de Luca, C.7
D'adamio, L.8
Palumbo, G.9
Formisano, S.10
Vito, P.11
Leonardi, A.12
-
117
-
-
0035144493
-
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
-
McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 21: 1249-1259, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1249-1259
-
-
McCullough, K.D.1
Martindale, J.L.2
Klotz, L.O.3
Aw, T.Y.4
Holbrook, N.J.5
-
118
-
-
77952722353
-
ER stress and the unfolded protein response in intestinal inflammation
-
McGuckin MA, Eri RD, Das I, Lourie R, Florin TH. ER stress and the unfolded protein response in intestinal inflammation. Am J Physiol Gastrointest Liver Physiol 298: G820-G832, 2010.
-
(2010)
Am J Physiol Gastrointest Liver Physiol
, vol.298
-
-
McGuckin, M.A.1
Eri, R.D.2
Das, I.3
Lourie, R.4
Florin, T.H.5
-
119
-
-
34447120709
-
Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians
-
Meex SJR, van Greevenbroek MMJ, Ayoubi TA, Vlietinck R, van Vliet-Ostaptchouk JV, Hofker MH, Vermeulen VMMJ, Schalkwijk CG, Feskens EJM, Boer JMA, Stehouwer CDA, van der Kallen CJH, de Bruin TWA. Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians. J Clin Endocrinol Metab 92: 2720-2725, 2007.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 2720-2725
-
-
Meex, S.J.R.1
van Greevenbroek, M.M.J.2
Ayoubi, T.A.3
Vlietinck, R.4
van Vliet-Ostaptchouk, J.V.5
Hofker, M.H.6
Vermeulen, V.M.M.J.7
Schalkwijk, C.G.8
Feskens, E.J.M.9
Boer, J.M.A.10
Stehouwer, C.D.A.11
van der Kallen, C.J.H.12
de Bruin, T.W.A.13
-
120
-
-
77952675374
-
ER stress in cardiovascular disease
-
Minamino T, Kitakaze M. ER stress in cardiovascular disease. J Mol Cell Cardiol 48: 1105-1110, 2010.
-
(2010)
J Mol Cell Cardiol
, vol.48
, pp. 1105-1110
-
-
Minamino, T.1
Kitakaze, M.2
-
121
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 451: 1069-1075, 2008.
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
122
-
-
36348943088
-
Integrated endoplasmic reticulum stress responses in cancer
-
Moenner M, Pluquet O, Bouchecareilh M, Chevet E. Integrated endoplasmic reticulum stress responses in cancer. Cancer Res 67: 10631-10634, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 10631-10634
-
-
Moenner, M.1
Pluquet, O.2
Bouchecareilh, M.3
Chevet, E.4
-
123
-
-
0030228708
-
Signalling from endoplasmic reticulum to nucleus: Transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway
-
Mori K, Kawahara T, Yoshida H, Yanagi H, Yura T. Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway. Genes Cells 1: 803-817, 1996.
-
(1996)
Genes Cells
, vol.1
, pp. 803-817
-
-
Mori, K.1
Kawahara, T.2
Yoshida, H.3
Yanagi, H.4
Yura, T.5
-
124
-
-
70349652275
-
Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation
-
Murakami T, Saito A, Hino S, Kondo S, Kanemoto S, Chihara K, Sekiya H, Tsumagari K, Ochiai K, Yoshinaga K, Saitoh M, Nishimura R, Yoneda T, Kou I, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Wanaka A, Imaizumi K. Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation. Nat Cell Biol 11: 1205-1211, 2009.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1205-1211
-
-
Murakami, T.1
Saito, A.2
Hino, S.3
Kondo, S.4
Kanemoto, S.5
Chihara, K.6
Sekiya, H.7
Tsumagari, K.8
Ochiai, K.9
Yoshinaga, K.10
Saitoh, M.11
Nishimura, R.12
Yoneda, T.13
Kou, I.14
Furuichi, T.15
Ikegawa, S.16
Ikawa, M.17
Okabe, M.18
Wanaka, A.19
Imaizumi, K.20
more..
-
125
-
-
58949093382
-
USP14 inhibits ER-associated degradation via interaction with IRE1alpha
-
Nagai A, Kadowaki H, Maruyama T, Takeda K, Nishitoh H, Ichijo H. USP14 inhibits ER-associated degradation via interaction with IRE1alpha. Biochem Biophys Res Commun 379: 995-1000, 2009.
-
(2009)
Biochem Biophys Res Commun
, vol.379
, pp. 995-1000
-
-
Nagai, A.1
Kadowaki, H.2
Maruyama, T.3
Takeda, K.4
Nishitoh, H.5
Ichijo, H.6
-
126
-
-
67349217063
-
ER and aging-Protein folding and the ER stress response
-
Naidoo N. ER and aging-Protein folding and the ER stress response. Ageing Res Rev 8: 150-159, 2009.
-
(2009)
Ageing Res Rev
, vol.8
, pp. 150-159
-
-
Naidoo, N.1
-
127
-
-
78149339310
-
Amyotrophic lateral sclerosis pathogenesis: A journey through the secretory pathway
-
Nassif M, Matus S, Castillo K, Hetz C. Amyotrophic lateral sclerosis pathogenesis: a journey through the secretory pathway. Antioxid Redox Signal 13: 1955-1989, 2010.
-
(2010)
Antioxid Redox Signal
, vol.13
, pp. 1955-1989
-
-
Nassif, M.1
Matus, S.2
Castillo, K.3
Hetz, C.4
-
128
-
-
71549130987
-
Direct proteasome binding and subsequent degradation of unspliced XBP-1 prevent its intracellular aggregation
-
Navon A, Gatushkin A, Zelcbuch L, Shteingart S, Farago M, Hadar R, Tirosh B. Direct proteasome binding and subsequent degradation of unspliced XBP-1 prevent its intracellular aggregation. FEBS Lett 584: 67-73, 2010.
-
(2010)
FEBS Lett
, vol.584
, pp. 67-73
-
-
Navon, A.1
Gatushkin, A.2
Zelcbuch, L.3
Shteingart, S.4
Farago, M.5
Hadar, R.6
Tirosh, B.7
-
129
-
-
33750935613
-
Functionality of unspliced XBP1 is required to explain evolution of overlapping reading frames
-
Nekrutenko A, He J. Functionality of unspliced XBP1 is required to explain evolution of overlapping reading frames. Trends Genet 22: 645-648, 2006.
-
(2006)
Trends Genet
, vol.22
, pp. 645-648
-
-
Nekrutenko, A.1
He, J.2
-
130
-
-
4344598305
-
Nck-dependent activation of extracellular signalregulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress
-
Nguyen DT, Kebache S, Fazel A, Wong HN, Jenna S, Emadali A, Lee EH, Bergeron JJ, Kaufman RJ, Larose L, Chevet E. Nck-dependent activation of extracellular signalregulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress. Mol Biol Cell 15: 4248-4260, 2004.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 4248-4260
-
-
Nguyen, D.T.1
Kebache, S.2
Fazel, A.3
Wong, H.N.4
Jenna, S.5
Emadali, A.6
Lee, E.H.7
Bergeron, J.J.8
Kaufman, R.J.9
Larose, L.10
Chevet, E.11
-
131
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K, Hori S, Kakizuka A, Ichijo H. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 16: 1345-1355, 2002.
-
(2002)
Genes Dev
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
Matsuzawa, A.2
Tobiume, K.3
Saegusa, K.4
Takeda, K.5
Inoue, K.6
Hori, S.7
Kakizuka, A.8
Ichijo, H.9
-
132
-
-
23644433913
-
Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease
-
Niwa M, Patil CK, DeRisi J, Walter P. Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease. Genome Biol 6: R3, 2005.
-
(2005)
Genome Biol
, vol.6
-
-
Niwa, M.1
Patil, C.K.2
Derisi, J.3
Walter, P.4
-
133
-
-
33845459165
-
Autophagy is activated for cell survival after endoplasmic reticulum stress
-
Ogata M, Hino S, Saito A, Morikawa K, Kondo S, Kanemoto S, Murakami T, Taniguchi M, Tanii I, Yoshinaga K, Shiosaka S, Hammarback JA, Urano F, Imaizumi K. Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol Cell Biol 26: 9220-9231, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 9220-9231
-
-
Ogata, M.1
Hino, S.2
Saito, A.3
Morikawa, K.4
Kondo, S.5
Kanemoto, S.6
Murakami, T.7
Taniguchi, M.8
Tanii, I.9
Yoshinaga, K.10
Shiosaka, S.11
Hammarback, J.A.12
Urano, F.13
Imaizumi, K.14
-
134
-
-
76749151048
-
Positive contribution of the IRE1alpha-XBP1 pathway to placental expression of CEA family genes
-
Oikawa D, Akai R, Iwawaki T. Positive contribution of the IRE1alpha-XBP1 pathway to placental expression of CEA family genes. FEBS Lett 584: 1066-1070, 2010.
-
(2010)
FEBS Lett
, vol.584
, pp. 1066-1070
-
-
Oikawa, D.1
Akai, R.2
Iwawaki, T.3
-
135
-
-
67651045789
-
Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins
-
Oikawa D, Kimata Y, Kohno K, Iwawaki T. Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins. Exp Cell Res 315: 2496-2504, 2009.
-
(2009)
Exp Cell Res
, vol.315
, pp. 2496-2504
-
-
Oikawa, D.1
Kimata, Y.2
Kohno, K.3
Iwawaki, T.4
-
136
-
-
77956016131
-
Identification of a consensus element recognized and cleaved by IRE1 alpha
-
Oikawa D, Tokuda M, Hosoda A, Iwawaki T. Identification of a consensus element recognized and cleaved by IRE1 alpha. Nucleic Acids Res 38: 6265-6273, 2010.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 6265-6273
-
-
Oikawa, D.1
Tokuda, M.2
Hosoda, A.3
Iwawaki, T.4
-
137
-
-
0032807338
-
ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin
-
Oliver JD, Roderick HL, Llewellyn DH, High S. ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin. Mol Biol Cell 10: 2573-2582, 1999.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 2573-2582
-
-
Oliver, J.D.1
Roderick, H.L.2
Llewellyn, D.H.3
High, S.4
-
138
-
-
77955410103
-
Modeling the endoplasmic reticulum unfolded protein response
-
Onn A, Ron D. Modeling the endoplasmic reticulum unfolded protein response. Nat Struct Mol Biol 17: 924-925, 2010.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 924-925
-
-
Onn, A.1
Ron, D.2
-
139
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Görgün C, Glimcher LH, Hotamisligil GS. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306: 457-461, 2004.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Görgün, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
140
-
-
79251589342
-
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
-
Papandreou I, Denko NC, Olson M, Van Melckebeke H, Lust S, Tam A, Solow- Cordero DE, Bouley DM, Offner F, Niwa M, Koong AC. Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma. Blood 117: 1311-1314, 2011.
-
(2011)
Blood
, vol.117
, pp. 1311-1314
-
-
Papandreou, I.1
Denko, N.C.2
Olson, M.3
van Melckebeke, H.4
Lust, S.5
Tam, A.6
Solow- cordero, D.E.7
Bouley, D.M.8
Offner, F.9
Niwa, M.10
Koong, A.C.11
-
141
-
-
77950523710
-
The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation
-
Park SW, Zhou Y, Lee J, Lu A, Sun C, Chung J, Ueki K, Ozcan U. The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation. Nature Med 16: 429-437, 2010.
-
(2010)
Nature Med
, vol.16
, pp. 429-437
-
-
Park, S.W.1
Zhou, Y.2
Lee, J.3
Lu, A.4
Sun, C.5
Chung, J.6
Ueki, K.7
Ozcan, U.8
-
142
-
-
0036840193
-
The cellular response to aggregated proteins associated with human disease
-
Perlmutter DH. The cellular response to aggregated proteins associated with human disease. J Clin Invest 110: 1219-1220, 2002.
-
(2002)
J Clin Invest
, vol.110
, pp. 1219-1220
-
-
Perlmutter, D.H.1
-
143
-
-
77955023666
-
BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response
-
Pincus D, Chevalier MW, Aragon T, van Anken E, Vidal SE, El-Samad H, Walter P. BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response. PLoS Biol 8: e1000415, 2010.
-
(2010)
PLoS Biol
, vol.8
-
-
Pincus, D.1
Chevalier, M.W.2
Aragon, T.3
van Anken, E.4
Vidal, S.E.5
El-Samad, H.6
Walter, P.7
-
144
-
-
34250758642
-
ER stress triggers apoptosis by activating BH3-only protein Bim
-
Puthalakath H, O'Reilly LA, Gunn P, Lee L, Kelly PN, Huntington ND, Hughes PD, Michalak EM, McKimm-Breschkin J, Motoyama N, Gotoh T, Akira S, Bouillet P, Strasser A. ER stress triggers apoptosis by activating BH3-only protein Bim. Cell 129: 1337-1349, 2007.
-
(2007)
Cell
, vol.129
, pp. 1337-1349
-
-
Puthalakath, H.1
O'Reilly, L.A.2
Gunn, P.3
Lee, L.4
Kelly, P.N.5
Huntington, N.D.6
Hughes, P.D.7
Michalak, E.M.8
McKimm-Breschkin, J.9
Motoyama, N.10
Gotoh, T.11
Akira, S.12
Bouillet, P.13
Strasser, A.14
-
145
-
-
77951645463
-
A crucial role for RACK1 in the regulation of glucosestimulated IRE1alpha activation in pancreatic beta cells
-
Qiu Y, Mao T, Zhang Y, Shao M, You J, Ding Q, Chen Y, Wu D, Xie D, Lin X, Gao X, Kaufman RJ, Li W, Liu Y. A crucial role for RACK1 in the regulation of glucosestimulated IRE1alpha activation in pancreatic beta cells. Sci Signal 3: ra7, 2010.
-
(2010)
Sci Signal
, vol.3
, Issue.7
-
-
Qiu, Y.1
Mao, T.2
Zhang, Y.3
Shao, M.4
You, J.5
Ding, Q.6
Chen, Y.7
Wu, D.8
Xie, D.9
Lin, X.10
Gao, X.11
Kaufman, R.J.12
Li, W.13
Liu, Y.14
-
146
-
-
36749001066
-
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes
-
Rapoport TA. Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes. Nature 450: 663-669, 2007.
-
(2007)
Nature
, vol.450
, pp. 663-669
-
-
Rapoport, T.A.1
-
147
-
-
0042477717
-
Gene expression during ER stress-induced apoptosis in neurons: Induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway
-
Reimertz C, Kogel D, Rami A, Chittenden T, Prehn JH. Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J Cell Biol 162: 587-597, 2003.
-
(2003)
J Cell Biol
, vol.162
, pp. 587-597
-
-
Reimertz, C.1
Kogel, D.2
Rami, A.3
Chittenden, T.4
Prehn, J.H.5
-
148
-
-
0034650851
-
An essential role in liver development for transcription factor XBP-1
-
Reimold AM, Etkin A, Clauss I, Perkins A, Friend DS, Zhang J, Horton HF, Scott A, Orkin SH, Byrne MC, Grusby MJ, Glimcher LH. An essential role in liver development for transcription factor XBP-1. Genes Dev 14: 152-157, 2000.
-
(2000)
Genes Dev
, vol.14
, pp. 152-157
-
-
Reimold, A.M.1
Etkin, A.2
Clauss, I.3
Perkins, A.4
Friend, D.S.5
Zhang, J.6
Horton, H.F.7
Scott, A.8
Orkin, S.H.9
Byrne, M.C.10
Grusby, M.J.11
Glimcher, L.H.12
-
149
-
-
0035913294
-
Plasma cell differentiation requires the transcription factor XBP-1
-
Reimold AM, Iwakoshi NN, Manis J, Vallabhajosyula P, Szomolanyi-Tsuda E, Gravallese EM, Friend D, Grusby MJ, Alt F, Glimcher LH. Plasma cell differentiation requires the transcription factor XBP-1. Nature 412: 300-307, 2001.
-
(2001)
Nature
, vol.412
, pp. 300-307
-
-
Reimold, A.M.1
Iwakoshi, N.N.2
Manis, J.3
Vallabhajosyula, P.4
Szomolanyi-Tsuda, E.5
Gravallese, E.M.6
Friend, D.7
Grusby, M.J.8
Alt, F.9
Glimcher, L.H.10
-
150
-
-
78649700978
-
BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program
-
Ren D, Tu HC, Kim H, Wang GX, Bean GR, Takeuchi O, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH. BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program. Science 330: 1390-1393, 2010.
-
(2010)
Science
, vol.330
, pp. 1390-1393
-
-
Ren, D.1
Tu, H.C.2
Kim, H.3
Wang, G.X.4
Bean, G.R.5
Takeuchi, O.6
Jeffers, J.R.7
Zambetti, G.P.8
Hsieh, J.J.9
Cheng, E.H.10
-
151
-
-
77649135472
-
An essential role for XBP-1 in host protection against immune activation in C. elegans
-
Richardson CE, Kooistra T, Kim DH. An essential role for XBP-1 in host protection against immune activation in C. elegans. Nature 463: 1092-1095, 2010.
-
(2010)
Nature
, vol.463
, pp. 1092-1095
-
-
Richardson, C.E.1
Kooistra, T.2
Kim, D.H.3
-
153
-
-
79952705597
-
Integrating stress signals at the endoplasmic reticulum: The BCL-2 protein family rheostat
-
Rodriguez D, Rojas-Rivera D, Hetz C. Integrating stress signals at the endoplasmic reticulum: the BCL-2 protein family rheostat. Biochim Biophys Acta 1813: 564-574, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1813
, pp. 564-574
-
-
Rodriguez, D.1
Rojas-Rivera, D.2
Hetz, C.3
-
154
-
-
4344660747
-
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
-
Romero-Ramirez L, Cao H, Nelson D, Hammond E, Lee AH, Yoshida H, Mori K, Glimcher LH, Denko NC, Giaccia AJ, Le QT, Koong AC. XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. Cancer Res 64: 5943-5947, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 5943-5947
-
-
Romero-Ramirez, L.1
Cao, H.2
Nelson, D.3
Hammond, E.4
Lee, A.H.5
Yoshida, H.6
Mori, K.7
Glimcher, L.H.8
Denko, N.C.9
Giaccia, A.J.10
Le, Q.T.11
Koong, A.C.12
-
155
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8: 519-529, 2007.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
156
-
-
78651385207
-
Bifunctional apoptosis regulator (BAR), an endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER stress
-
Rong J, Chen L, Toth JI, Tcherpakov M, Petroski MD, Reed JC. Bifunctional apoptosis regulator (BAR), an endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER stress. J Biol Chem 286: 1453-1463, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 1453-1463
-
-
Rong, J.1
Chen, L.2
Toth, J.I.3
Tcherpakov, M.4
Petroski, M.D.5
Reed, J.C.6
-
157
-
-
79955499906
-
Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity
-
Rubio C, Pincus D, Korennykh A, Schuck S, El-Samad H, Walter P. Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity. J Cell Biol 193: 171-184, 2011.
-
(2011)
J Cell Biol
, vol.193
, pp. 171-184
-
-
Rubio, C.1
Pincus, D.2
Korennykh, A.3
Schuck, S.4
El-Samad, H.5
Walter, P.6
-
158
-
-
79954424872
-
Participation of lectin chaperones and thiol oxidoreductases in protein folding within the endoplasmic reticulum
-
Rutkevich LA, Williams DB. Participation of lectin chaperones and thiol oxidoreductases in protein folding within the endoplasmic reticulum. Curr Opin Cell Biol 23: 157-166, 2010.
-
(2010)
Curr Opin Cell Biol
, vol.23
, pp. 157-166
-
-
Rutkevich, L.A.1
Williams, D.B.2
-
159
-
-
70349652454
-
Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis
-
Saito A, Hino S, Murakami T, Kanemoto S, Kondo S, Saitoh M, Nishimura R, Yoneda T, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Imaizumi K. Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nat Cell Biol 11: 1197-1204, 2009.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1197-1204
-
-
Saito, A.1
Hino, S.2
Murakami, T.3
Kanemoto, S.4
Kondo, S.5
Saitoh, M.6
Nishimura, R.7
Yoneda, T.8
Furuichi, T.9
Ikegawa, S.10
Ikawa, M.11
Okabe, M.12
Imaizumi, K.13
-
160
-
-
74549169836
-
ER stress in Alzheimer's disease: A novel neuronal trigger for inflammation and Alzheimer's pathology
-
Salminen A, Kauppinen A, Suuronen T, Kaarniranta K, Ojala J. ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology. J Neuroinflammation 6: 41, 2009.
-
(2009)
J Neuroinflammation
, vol.6
, pp. 41
-
-
Salminen, A.1
Kauppinen, A.2
Suuronen, T.3
Kaarniranta, K.4
Ojala, J.5
-
161
-
-
22544444513
-
Control ofmRNAtranslation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis
-
Scheuner D, Vander Mierde D, Song B, Flamez D, Creemers JWM, Tsukamoto K, Ribick M, Schuit FC, Kaufman RJ. Control ofmRNAtranslation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis. Nature Med 11: 757-764, 2005.
-
(2005)
Nature Med
, vol.11
, pp. 757-764
-
-
Scheuner, D.1
Vander Mierde, D.2
Song, B.3
Flamez, D.4
Creemers, J.W.M.5
Tsukamoto, K.6
Ribick, M.7
Schuit, F.C.8
Kaufman, R.J.9
-
162
-
-
22244446505
-
The mammalian unfolded protein response
-
Schroder M, Kaufman RJ. The mammalian unfolded protein response. Annu Rev Biochem 74: 739-789, 2005.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 739-789
-
-
Schroder, M.1
Kaufman, R.J.2
-
163
-
-
28444497039
-
Mutations in SIL1 cause Marinesco-Sjögren syndrome, a cerebellar ataxia with cataract and myopathy
-
Senderek J, Krieger M, Stendel C, Bergmann C, Moser M, Breitbach-Faller N, Rudnik- Schöneborn S, Blaschek A, Wolf NI, Harting I, North K, Smith J, Muntoni F, Brockington M, Quijano-Roy S, Renault F, Herrmann R, Hendershot LM, Schröder JM, Lochmüller H, Topaloglu H, Voit T, Weis J, Ebinger F, Zerres K. Mutations in SIL1 cause Marinesco-Sjögren syndrome, a cerebellar ataxia with cataract and myopathy. Nature Genet 37: 1312-1314, 2005.
-
(2005)
Nature Genet
, vol.37
, pp. 1312-1314
-
-
Senderek, J.1
Krieger, M.2
Stendel, C.3
Bergmann, C.4
Moser, M.5
Breitbach-Faller, N.6
Rudnik-Schöneborn, S.7
Blaschek, A.8
Wolf, N.I.9
Harting, I.10
North, K.11
Smith, J.12
Muntoni, F.13
Brockington, M.14
Quijano-Roy, S.15
Renault, F.16
Herrmann, R.17
Hendershot, L.M.18
Schröder, J.M.19
Lochmüller, H.20
Topaloglu, H.21
Voit, T.22
Weis, J.23
Ebinger, F.24
Zerres, K.25
more..
-
164
-
-
3142658576
-
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, increases protein synthesis in plasma cell differentiation
-
Shaffer AL, Shapiro-Shelef M, Iwakoshi NN, Lee AH, Qian SB, Zhao H, Yu X, Yang L, Tan BK, Rosenwald A, Hurt EM, Petroulakis E, Sonenberg N, Yewdell JW, Calame K, Glimcher LH, Staudt LM. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, increases protein synthesis in plasma cell differentiation. Immunity 21: 81-93, 2004.
-
(2004)
Immunity
, vol.21
, pp. 81-93
-
-
Shaffer, A.L.1
Shapiro-Shelef, M.2
Iwakoshi, N.N.3
Lee, A.H.4
Qian, S.B.5
Zhao, H.6
Yu, X.7
Yang, L.8
Tan, B.K.9
Rosenwald, A.10
Hurt, E.M.11
Petroulakis, E.12
Sonenberg, N.13
Yewdell, J.W.14
Calame, K.15
Glimcher, L.H.16
Staudt, L.M.17
-
165
-
-
79954426157
-
Signaling cell death from the endoplasmic reticulum stress response
-
Shore GC, Papa FR, Oakes SA. Signaling cell death from the endoplasmic reticulum stress response. Curr Opin Cell Biol 23: 143-149, 2011.
-
(2011)
Curr Opin Cell Biol
, vol.23
, pp. 143-149
-
-
Shore, G.C.1
Papa, F.R.2
Oakes, S.A.3
-
166
-
-
0030954870
-
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response
-
Sidrauski C, Walter P. The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell 90: 1031-1039, 1997.
-
(1997)
Cell
, vol.90
, pp. 1031-1039
-
-
Sidrauski, C.1
Walter, P.2
-
167
-
-
28244466782
-
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism
-
Silva RM, Ries V, Oo TF, Yarygina O, Jackson-Lewis V, Ryu EJ, Lu PD, Marciniak SJ, Ron D, Przedborski S, Kholodilov N, Greene LA, Burke RE. CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism. J Neurochem 95: 974-986, 2005.
-
(2005)
J Neurochem
, vol.95
, pp. 974-986
-
-
Silva, R.M.1
Ries, V.2
Oo, T.F.3
Yarygina, O.4
Jackson-Lewis, V.5
Ryu, E.J.6
Lu, P.D.7
Marciniak, S.J.8
Ron, D.9
Przedborski, S.10
Kholodilov, N.11
Greene, L.A.12
Burke, R.E.13
-
168
-
-
34147172715
-
Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis
-
Sriburi R, Bommiasamy H, Buldak GL, Robbins GR, Frank M, Jackowski S, Brewer JW. Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis. J Biol Chem 282: 7024-7034, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 7024-7034
-
-
Sriburi, R.1
Bommiasamy, H.2
Buldak, G.L.3
Robbins, G.R.4
Frank, M.5
Jackowski, S.6
Brewer, J.W.7
-
169
-
-
5444222234
-
XBP1: A link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum
-
Sriburi R, Jackowski S, Mori K, Brewer JW. XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. J Cell Biol 167: 35-41, 2004.
-
(2004)
J Cell Biol
, vol.167
, pp. 35-41
-
-
Sriburi, R.1
Jackowski, S.2
Mori, K.3
Brewer, J.W.4
-
171
-
-
30044441047
-
CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P
-
Stirling J, O'Hare P. CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P. Mol Biol Cell 17: 413-426, 2006.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 413-426
-
-
Stirling, J.1
O'Hare, P.2
-
172
-
-
35448994352
-
Insulin gene mutations as a cause of permanent neonatal diabetes
-
Group NDIC
-
Støy J, Edghill EL, Flanagan SE, Ye H, Paz VP, Pluzhnikov A, Below JE, Hayes MG, Cox NJ, Lipkind GM, Lipton RB, Greeley SAW, Patch AM, Ellard S, Steiner DF, Hattersley AT, Philipson LH, Bell GI, Group NDIC. Insulin gene mutations as a cause of permanent neonatal diabetes. Proc Natl Acad Sci USA 104: 15040-15044, 2007.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15040-15044
-
-
Støy, J.1
Edghill, E.L.2
Flanagan, S.E.3
Ye, H.4
Paz, V.P.5
Pluzhnikov, A.6
Below, J.E.7
Hayes, M.G.8
Cox, N.J.9
Lipkind, G.M.10
Lipton, R.B.11
Greeley, S.A.W.12
Patch, A.M.13
Ellard, S.14
Steiner, D.F.15
Hattersley, A.T.16
Philipson, L.H.17
Bell, G.I.18
-
173
-
-
77958003056
-
The role of endoplasmic reticulum stress in the progression of atherosclerosis
-
Tabas I. The role of endoplasmic reticulum stress in the progression of atherosclerosis. Circ Res 107: 839-850, 2010.
-
(2010)
Circ Res
, vol.107
, pp. 839-850
-
-
Tabas, I.1
-
174
-
-
77954311602
-
Pathogenesis of ankylosing spondylitis
-
Tam LS, Gu J, Yu D. Pathogenesis of ankylosing spondylitis. Nature Rev Rheumatol 6: 399-405, 2010.
-
(2010)
Nature Rev Rheumatol
, vol.6
, pp. 399-405
-
-
Tam, L.S.1
Gu, J.2
Yu, D.3
-
175
-
-
33644774734
-
Association of amino acid variants in the activating transcription factor 6 gene (ATF6) on 1q21-q23 with type 2 diabetes in Pima Indians
-
Thameem F, Farook VS, Bogardus C, Prochazka M. Association of amino acid variants in the activating transcription factor 6 gene (ATF6) on 1q21-q23 with type 2 diabetes in Pima Indians. Diabetes 55: 839-842, 2006.
-
(2006)
Diabetes
, vol.55
, pp. 839-842
-
-
Thameem, F.1
Farook, V.S.2
Bogardus, C.3
Prochazka, M.4
-
176
-
-
50249116184
-
The endoplasmic reticulum stress response in immunity and autoimmunity
-
Todd DJ, Lee AH, Glimcher LH. The endoplasmic reticulum stress response in immunity and autoimmunity. Nat Rev Immunol 8: 663-674, 2008.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 663-674
-
-
Todd, D.J.1
Lee, A.H.2
Glimcher, L.H.3
-
177
-
-
70350452319
-
XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development
-
Todd DJ, McHeyzer-Williams LJ, Kowal C, Lee AH, Volpe BT, Diamond B, McHeyzer-Williams MG, Glimcher LH. XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development. J Exp Med 206: 2151-2159, 2009.
-
(2009)
J Exp Med
, vol.206
, pp. 2151-2159
-
-
Todd, D.J.1
McHeyzer-Williams, L.J.2
Kowal, C.3
Lee, A.H.4
Volpe, B.T.5
Diamond, B.6
Mcheyzer-Williams, M.G.7
Glimcher, L.H.8
-
178
-
-
33846194065
-
HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: Implications for the pathogenesis of spondylarthritis-like disease
-
Turner MJ, Delay ML, Bai S, Klenk E, Colbert RA. HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: Implications for the pathogenesis of spondylarthritis-like disease. Arthritis Rheum 56: 215-223, 2007.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 215-223
-
-
Turner, M.J.1
Delay, M.L.2
Bai, S.3
Klenk, E.4
Colbert, R.A.5
-
179
-
-
70350005336
-
Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response
-
Uemura A, Oku M, Mori K, Yoshida H. Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response. J Cell Sci 122: 2877-2886, 2009.
-
(2009)
J Cell Sci
, vol.122
, pp. 2877-2886
-
-
Uemura, A.1
Oku, M.2
Mori, K.3
Yoshida, H.4
-
180
-
-
0033693855
-
IRE1 and efferent signaling from the endoplasmic reticulum
-
Urano F, Bertolotti A, Ron D. IRE1 and efferent signaling from the endoplasmic reticulum. J Cell Sci 113: 3697-3702, 2000.
-
(2000)
J Cell Sci
, vol.113
, pp. 3697-3702
-
-
Urano, F.1
Bertolotti, A.2
Ron, D.3
-
181
-
-
56749176947
-
One step at a time: Endoplasmic reticulum-associated degradation
-
Vembar SS, Brodsky JL. One step at a time: endoplasmic reticulum-associated degradation. Nat Rev Mol Cell Biol 9: 944-957, 2008.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 944-957
-
-
Vembar, S.S.1
Brodsky, J.L.2
-
182
-
-
79953319782
-
Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease
-
Volkmann K, Lucas JL, Vuga D, Wang X, Brumm D, Stiles C, Kriebel D, Der-Sarkissian A, Krishnan K, Schweitzer C, Liu Z, Malyankar UM, Chiovitti D, Canny M, Durocher D, Sicheri F, Patterson JB. Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease. J Biol Chem 286: 12743-12755, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 12743-12755
-
-
Volkmann, K.1
Lucas, J.L.2
Vuga, D.3
Wang, X.4
Brumm, D.5
Stiles, C.6
Kriebel, D.7
Der-Sarkissian, A.8
Krishnan, K.9
Schweitzer, C.10
Liu, Z.11
Malyankar, U.M.12
Chiovitti, D.13
Canny, M.14
Durocher, D.15
Sicheri, F.16
Patterson, J.B.17
-
183
-
-
79551474362
-
Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation
-
Wang FM, Chen YJ, Ouyang HJ. Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation. Biochem J 433: 245-252, 2010.
-
(2010)
Biochem J
, vol.433
, pp. 245-252
-
-
Wang, F.M.1
Chen, Y.J.2
Ouyang, H.J.3
-
184
-
-
79551584057
-
The unfolded protein response in familial amyotrophic lateral sclerosis
-
Wang L, Popko B, Roos RP. The unfolded protein response in familial amyotrophic lateral sclerosis. Hum Mol Genet 20: 1008-1015, 2011.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 1008-1015
-
-
Wang, L.1
Popko, B.2
Roos, R.P.3
-
185
-
-
77649253906
-
Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity
-
Wang Y, Inoue H, Ravnskjaer K, Viste K, Miller N, Liu Y, Hedrick S, Vera L, Montminy M. Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity. Proc Natl Acad Sci USA 107: 3087-3092, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 3087-3092
-
-
Wang, Y.1
Inoue, H.2
Ravnskjaer, K.3
Viste, K.4
Miller, N.5
Liu, Y.6
Hedrick, S.7
Vera, L.8
Montminy, M.9
-
186
-
-
67749135249
-
The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis
-
Wang Y, Vera L, Fischer WH, Montminy M. The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis. Nature 460: 534-537, 2009.
-
(2009)
Nature
, vol.460
, pp. 534-537
-
-
Wang, Y.1
Vera, L.2
Fischer, W.H.3
Montminy, M.4
-
187
-
-
67749096213
-
Proinsulin and the genetics of diabetes mellitus
-
Weiss MA. Proinsulin and the genetics of diabetes mellitus. J Biol Chem 284: 19159- 19163, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 19159-19163
-
-
Weiss, M.A.1
-
188
-
-
33645080188
-
Beyond lectins: The calnexin/calreticulin chaperone system of the endoplasmic reticulum
-
Williams DB. Beyond lectins: the calnexin/calreticulin chaperone system of the endoplasmic reticulum. J Cell Sci 119: 615-623, 2006.
-
(2006)
J Cell Sci
, vol.119
, pp. 615-623
-
-
Williams, D.B.1
-
189
-
-
77950537400
-
A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response
-
Winnay JN, Boucher J, Mori MA, Ueki K, Kahn CR. A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response. Nat Med 16: 438-445, 2010.
-
(2010)
Nat Med
, vol.16
, pp. 438-445
-
-
Winnay, J.N.1
Boucher, J.2
Mori, M.A.3
Ueki, K.4
Kahn, C.R.5
-
190
-
-
77950887221
-
Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1
-
Wiseman RL, Zhang Y, Lee KP, Harding HP, Haynes CM, Price J, Sicheri F, Ron D. Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Mol Cell 38: 291-304, 2010.
-
(2010)
Mol Cell
, vol.38
, pp. 291-304
-
-
Wiseman, R.L.1
Zhang, Y.2
Lee, K.P.3
Harding, H.P.4
Haynes, C.M.5
Price, J.6
Sicheri, F.7
Ron, D.8
-
191
-
-
79958033194
-
Modulating stress responses by the UPRosome: A matter of life and death
-
1016/j.tibs, 03.0012011
-
Woehlbier U, Hetz C. Modulating stress responses by the UPRosome: a matter of life and death. Trends Biochem Sci 10.1016/j.tibs.2011.03.0012011.
-
(2011)
Trends Biochem Sci
, vol.10
-
-
Woehlbier, U.1
Hetz, C.2
-
192
-
-
34548172495
-
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1
-
Yamamoto K, Sato T, Matsui T, Sato M, Okada T, Yoshida H, Harada A, Mori K. Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1. Dev Cell 13: 365-376, 2007.
-
(2007)
Dev Cell
, vol.13
, pp. 365-376
-
-
Yamamoto, K.1
Sato, T.2
Matsui, T.3
Sato, M.4
Okada, T.5
Yoshida, H.6
Harada, A.7
Mori, K.8
-
193
-
-
64749103329
-
Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA
-
Yanagitani K, Imagawa Y, Iwawaki T, Hosoda A, Saito M, Kimata Y, Kohno K. Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA. Mol Cell 34: 191-200, 2009.
-
(2009)
Mol Cell
, vol.34
, pp. 191-200
-
-
Yanagitani, K.1
Imagawa, Y.2
Iwawaki, T.3
Hosoda, A.4
Saito, M.5
Kimata, Y.6
Kohno, K.7
-
194
-
-
79551629027
-
Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA
-
Yanagitani K, Kimata Y, Kadokura H, Kohno K. Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA. Science 331: 586-589, 2011.
-
(2011)
Science
, vol.331
, pp. 586-589
-
-
Yanagitani, K.1
Kimata, Y.2
Kadokura, H.3
Kohno, K.4
-
195
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107: 881-891, 2001.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
196
-
-
0033815971
-
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response
-
Yoshida H, Okada T, Haze K, Yanagi H, Yura T, Negishi M, Mori K. ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response. Mol Cell Biol 20: 6755-6767, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6755-6767
-
-
Yoshida, H.1
Okada, T.2
Haze, K.3
Yanagi, H.4
Yura, T.5
Negishi, M.6
Mori, K.7
-
197
-
-
32644432826
-
pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response
-
Yoshida H, Oku M, Suzuki M, Mori K. pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response. J Cell Biol 172: 565-575, 2006.
-
(2006)
J Cell Biol
, vol.172
, pp. 565-575
-
-
Yoshida, H.1
Oku, M.2
Suzuki, M.3
Mori, K.4
-
198
-
-
37549048249
-
The BCL-2 protein family: Opposing activities that mediate cell death
-
Youle RJ, Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 9: 47-59, 2008.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
199
-
-
32044453080
-
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
-
Zhang K, Shen X, Wu J, Sakaki K, Saunders T, Rutkowski DT, Back SH, Kaufman RJ. Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Cell 124: 587-599, 2006.
-
(2006)
Cell
, vol.124
, pp. 587-599
-
-
Zhang, K.1
Shen, X.2
Wu, J.3
Sakaki, K.4
Saunders, T.5
Rutkowski, D.T.6
Back, S.H.7
Kaufman, R.J.8
-
200
-
-
79953794116
-
The unfolded protein response transducer IRE1alpha prevents ER stress-induced hepatic steatosis
-
Zhang K, Wang S, Malhotra J, Hassler JR, Back SH, Wang G, Chang L, Xu W, Miao H, Leonardi R, Chen YE, Jackowski S, Kaufman RJ. The unfolded protein response transducer IRE1alpha prevents ER stress-induced hepatic steatosis. EMBO J 30: 1357-1375, 2011.
-
(2011)
EMBO J
, vol.30
, pp. 1357-1375
-
-
Zhang, K.1
Wang, S.2
Malhotra, J.3
Hassler, J.R.4
Back, S.H.5
Wang, G.6
Chang, L.7
Xu, W.8
Miao, H.9
Leonardi, R.10
Chen, Y.E.11
Jackowski, S.12
Kaufman, R.J.13
-
201
-
-
14944371187
-
The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis
-
Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ. The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. J Clin Invest 115: 268-281, 2005.
-
(2005)
J Clin Invest
, vol.115
, pp. 268-281
-
-
Zhang, K.1
Wong, H.N.2
Song, B.3
Miller, C.N.4
Scheuner, D.5
Kaufman, R.J.6
-
202
-
-
0036091476
-
The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas
-
Zhang P, Mcgrath B, Li Sa Frank A, Zambito F, Reinert J, Gannon M, Ma K, Mcnaughton K, Cavener DR. The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas. Mol Cell Biol 22: 3864-3874, 2002.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3864-3874
-
-
Zhang, P.1
McGrath, B.2
li Sa Frank, A.3
Zambito, F.4
Reinert, J.5
Gannon, M.6
Ma, K.7
McNaughton, K.8
Cavener, D.R.9
-
203
-
-
74749103667
-
Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/-mice
-
Zhao F, Edwards R, Dizon D, Afrasiabi K, Mastroianni JR, Geyfman M, Ouellette AJ, Andersen B, Lipkin SM. Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/-mice. Dev Biol 338: 270-279, 2010.
-
(2010)
Dev Biol
, vol.338
, pp. 270-279
-
-
Zhao, F.1
Edwards, R.2
Dizon, D.3
Afrasiabi, K.4
Mastroianni, J.R.5
Geyfman, M.6
Ouellette, A.J.7
Andersen, B.8
Lipkin, S.M.9
-
204
-
-
25144520251
-
Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP
-
Zhao L, Longo-Guess C, Harris BS, Lee JW, Ackerman SL. Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP. Nature Genet 37: 974-979, 2005.
-
(2005)
Nature Genet
, vol.37
, pp. 974-979
-
-
Zhao, L.1
Longo-Guess, C.2
Harris, B.S.3
Lee, J.W.4
Ackerman, S.L.5
-
205
-
-
77649314881
-
Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco-Sjögren syndrome
-
Zhao L, Rosales C, Seburn K, Ron D, Ackerman SL. Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco-Sjögren syndrome. Hum Mol Genet 19: 25-35, 2010.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 25-35
-
-
Zhao, L.1
Rosales, C.2
Seburn, K.3
Ron, D.4
Ackerman, S.L.5
-
206
-
-
33749233991
-
The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response
-
Zhou J, Liu CY, Back SH, Clark RL, Peisach D, Xu Z, Kaufman RJ. The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response. Proc Natl Acad Sci USA 103: 14343-14348, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 14343-14348
-
-
Zhou, J.1
Liu, C.Y.2
Back, S.H.3
Clark, R.L.4
Peisach, D.5
Xu, Z.6
Kaufman, R.J.7
-
207
-
-
79952381078
-
Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction
-
Zhou Y, Lee J, Reno CM, Sun C, Park SW, Chung J, Fisher SJ, White MF, Biddinger SB, Ozcan U. Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction. Nat Med 17: 356-365, 2011.
-
(2011)
Nat Med
, vol.17
, pp. 356-365
-
-
Zhou, Y.1
Lee, J.2
Reno, C.M.3
Sun, C.4
Park, S.W.5
Chung, J.6
Fisher, S.J.7
White, M.F.8
Biddinger, S.B.9
Ozcan, U.10
-
208
-
-
0032054744
-
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
-
Zinszner H, Kuroda M, Wang X, Batchvarova N, Lightfoot RT, Remotti H, Stevens JL, Ron D. CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev 12: 982-995, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 982-995
-
-
Zinszner, H.1
Kuroda, M.2
Wang, X.3
Batchvarova, N.4
Lightfoot, R.T.5
Remotti, H.6
Stevens, J.L.7
Ron, D.8
|