-
1
-
-
0031473345
-
Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex
-
Beckmann, R., Bubeck, D., Grassucci, R., Penczek, P., Verschoor, A., Blobel, G., and Frank, J. (1997). Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex. Science 278, 2123-2126.
-
(1997)
Science
, vol.278
, pp. 2123-2126
-
-
Beckmann, R.1
Bubeck, D.2
Grassucci, R.3
Penczek, P.4
Verschoor, A.5
Blobel, G.6
Frank, J.7
-
2
-
-
0030031666
-
Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide
-
Bell, C.E., and Eisenberg, D. (1996). Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide. Biochemistry 35, 1137-1149.
-
(1996)
Biochemistry
, vol.35
, pp. 1137-1149
-
-
Bell, C.E.1
Eisenberg, D.2
-
3
-
-
0027759380
-
A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome
-
Brodsky, J.L., and Schekman, R. (1993). A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome. J. Cell Biol. 123, 1355-1363.
-
(1993)
J. Cell Biol.
, vol.123
, pp. 1355-1363
-
-
Brodsky, J.L.1
Schekman, R.2
-
4
-
-
0028822223
-
BiP and Sec63p are required forboth co- and posttranslational protein translocation into the yeast endoplasmic reticulum
-
Brodsky, J.L., Goeckeler, J., and Schekman, R. (1995). BiP and Sec63p are required forboth co- and posttranslational protein translocation into the yeast endoplasmic reticulum. Proc. Natl. Acad. Sci. USA 92, 9643-9646.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9643-9646
-
-
Brodsky, J.L.1
Goeckeler, J.2
Schekman, R.3
-
5
-
-
0023720121
-
Defective co-translational formation of disulphide-isomerase-deficient microsomes
-
Bulleid, N.J., and Freedman, R.B. (1988). Defective co-translational formation of disulphide-isomerase-deficient microsomes. Nature 335, 649-651.
-
(1988)
Nature
, vol.335
, pp. 649-651
-
-
Bulleid, N.J.1
Freedman, R.B.2
-
6
-
-
0030930513
-
The lumenal domain of Sec63p stimulates the ATPase activity of BiP and mediates BiP recruitment to the translocon in Saccharomyces cerevisiae
-
Corsi, A.K., and Schekman, R. (1997). The lumenal domain of Sec63p stimulates the ATPase activity of BiP and mediates BiP recruitment to the translocon in Saccharomyces cerevisiae. J. Cell Biol. 137, 1483-1493.
-
(1997)
J. Cell Biol.
, vol.137
, pp. 1483-1493
-
-
Corsi, A.K.1
Schekman, R.2
-
7
-
-
0027162564
-
The signal sequence moves through a ribosomal tunnel into a noncytoplasmic aqueous environment at the ER membrane early in translocation
-
Crowley, K.S., Reinhart, G.D., and Johnson, A.E. (1993). The signal sequence moves through a ribosomal tunnel into a noncytoplasmic aqueous environment at the ER membrane early in translocation. Cell 73, 1101-1115.
-
(1993)
Cell
, vol.73
, pp. 1101-1115
-
-
Crowley, K.S.1
Reinhart, G.D.2
Johnson, A.E.3
-
8
-
-
0027985063
-
Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore
-
Crowley, K.S., Liao, S., Worrell, V.E., Reinhart, G.D., and Johnson, A.E. (1994). Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore. Cell 78, 461-471.
-
(1994)
Cell
, vol.78
, pp. 461-471
-
-
Crowley, K.S.1
Liao, S.2
Worrell, V.E.3
Reinhart, G.D.4
Johnson, A.E.5
-
9
-
-
0028938427
-
Autophosphorylation of grp94 (endoplasmin)
-
Csermely, P., Miyata, Y., Schnaider, T., and Yahara, I. (1995). Autophosphorylation of grp94 (endoplasmin). J. Biol. Chem. 270, 6381-6388.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 6381-6388
-
-
Csermely, P.1
Miyata, Y.2
Schnaider, T.3
Yahara, I.4
-
10
-
-
0342995731
-
The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process
-
Do, H., Falcone, D., Lin, J., Andrews, D.W., and Johnson, A.E. (1996). The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process. Cell 85, 369-378.
-
(1996)
Cell
, vol.85
, pp. 369-378
-
-
Do, H.1
Falcone, D.2
Lin, J.3
Andrews, D.W.4
Johnson, A.E.5
-
11
-
-
0025100372
-
Three-dimensional structure of the ATPase fragment of a 70K heat-shock cognate protein
-
Flaherty, K.M., De Luca-Flaherty, C., and McKay, D.B. (1990). Three-dimensional structure of the ATPase fragment of a 70K heat-shock cognate protein. Nature 346, 623-628.
-
(1990)
Nature
, vol.346
, pp. 623-628
-
-
Flaherty, K.M.1
De Luca-Flaherty, C.2
McKay, D.B.3
-
12
-
-
0026584271
-
Protein folding in the cell
-
Gething, M.J., and Sambrook, J. (1992). Protein folding in the cell. Nature 355, 33-45.
-
(1992)
Nature
, vol.355
, pp. 33-45
-
-
Gething, M.J.1
Sambrook, J.2
-
13
-
-
0030611388
-
The aqueous pore through the translocon has a diameter of 40-60 A during cotranslational protein translocation at the ER membrane
-
Hamman, B.D., Chen, J.-C., Johnson, E.E., and Johnson, A.E. (1997). The aqueous pore through the translocon has a diameter of 40-60 A during cotranslational protein translocation at the ER membrane. Cell 89, 535-544.
-
(1997)
Cell
, vol.89
, pp. 535-544
-
-
Hamman, B.D.1
Chen, J.-C.2
Johnson, E.E.3
Johnson, A.E.4
-
14
-
-
0345444027
-
Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation
-
Hanein, D., Matlack, K.E.S., Jungnickel, B., Plath, K., Kalies, K.-U., Miller, K.R., Rapoport, T.A., and Akey, C.W. (1996). Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation. Cell 87, 721-732.
-
(1996)
Cell
, vol.87
, pp. 721-732
-
-
Hanein, D.1
Matlack, K.E.S.2
Jungnickel, B.3
Plath, K.4
Kalies, K.-U.5
Miller, K.R.6
Rapoport, T.A.7
Akey, C.W.8
-
15
-
-
0029890917
-
Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants
-
Hendershot, L. , Wei, J., Gaut, J., Melnick, J., Aviel, S., and Argon, Y. (1996). Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants. Proc. Natl. Acad. Sci. USA 93, 5269-5274.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5269-5274
-
-
Hendershot, L.1
Wei, J.2
Gaut, J.3
Melnick, J.4
Aviel, S.5
Argon, Y.6
-
16
-
-
0031106619
-
Protein translocation at the ER membrane: A complex process becomes more so
-
Johnson, A.E. (1997). Protein translocation at the ER membrane: a complex process becomes more so. Trends Cell Biol. 7, 90-95.
-
(1997)
Trends Cell Biol.
, vol.7
, pp. 90-95
-
-
Johnson, A.E.1
-
17
-
-
0029096050
-
A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane
-
Jungnickel, B., and Rapoport, T.A. (1995). A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane. Cell 82, 261-270.
-
(1995)
Cell
, vol.82
, pp. 261-270
-
-
Jungnickel, B.1
Rapoport, T.A.2
-
18
-
-
0027953913
-
Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex
-
Kalies, K.-U., Görlich, D., and Rapoport, T.A. (1994). Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex. J. Cell Biol. 126, 925-934.
-
(1994)
J. Cell Biol.
, vol.126
, pp. 925-934
-
-
Kalies, K.-U.1
Görlich, D.2
Rapoport, T.A.3
-
19
-
-
0031471055
-
Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration
-
Liao, S., Lin, J., Do, H., and Johnson, A.E. (1997). Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration. Cell 90, 31-41.
-
(1997)
Cell
, vol.90
, pp. 31-41
-
-
Liao, S.1
Lin, J.2
Do, H.3
Johnson, A.E.4
-
20
-
-
0030970268
-
Binding of secretory precursor polypeptides to a translocon subcomplex is regulated by BiP
-
Lyman, S.K., and Schekman, R. (1997). Binding of secretory precursor polypeptides to a translocon subcomplex is regulated by BiP. Cell 88, 85-96.
-
(1997)
Cell
, vol.88
, pp. 85-96
-
-
Lyman, S.K.1
Schekman, R.2
-
21
-
-
0029620936
-
Sac1 mediates the adenosine triphoshate transport into yeast endoplasmic reticulum that is required for protein translocation
-
Mayinger, P., Bankaitis, V.A., and Meyer, D.I. (1995). Sac1 mediates the adenosine triphoshate transport into yeast endoplasmic reticulum that is required for protein translocation. J. Cell Biol. 131, 1377-1386.
-
(1995)
J. Cell Biol.
, vol.131
, pp. 1377-1386
-
-
Mayinger, P.1
Bankaitis, V.A.2
Meyer, D.I.3
-
22
-
-
0027238583
-
Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation
-
Nicchitta, C.V., and Blobel, G. (1993). Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation. Cell 73, 989-998.
-
(1993)
Cell
, vol.73
, pp. 989-998
-
-
Nicchitta, C.V.1
Blobel, G.2
-
23
-
-
0025970971
-
Binding protein BiP is required for translocation of secretory proteins into the endoplasmic reticulum in Saccharomyces cerevisiae
-
Nguyen, T.H., Law, D.T.S., and Williams, D.B. (1991). Binding protein BiP is required for translocation of secretory proteins into the endoplasmic reticulum in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 88, 1565-1569.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 1565-1569
-
-
Nguyen, T.H.1
Law, D.T.S.2
Williams, D.B.3
-
24
-
-
0028997459
-
Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p
-
Panzner, S., Dreier, L., Hartmann, E., Kostka, S., and Rapoport, T.A. (1995). Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p. Cell 81, 561-570.
-
(1995)
Cell
, vol.81
, pp. 561-570
-
-
Panzner, S.1
Dreier, L.2
Hartmann, E.3
Kostka, S.4
Rapoport, T.A.5
-
25
-
-
0024586112
-
Preparation and characterization of dog pancreas microsomal membranes specifically depleted of protein disulfide isomerase
-
Paver, J.L., Hawkins, H.C., and Freedman, R.B. (1989). Preparation and characterization of dog pancreas microsomal membranes specifically depleted of protein disulfide isomerase. Biochem. J. 257, 657-663.
-
(1989)
Biochem. J.
, vol.257
, pp. 657-663
-
-
Paver, J.L.1
Hawkins, H.C.2
Freedman, R.B.3
-
26
-
-
0030111259
-
The nascent polypeptide-associated complex modulates interactions between the signal recognition particle and the ribosome
-
Powers, T., and Walter, P. (1996). The nascent polypeptide-associated complex modulates interactions between the signal recognition particle and the ribosome. Curr. Biol. 6, 331-338.
-
(1996)
Curr. Biol.
, vol.6
, pp. 331-338
-
-
Powers, T.1
Walter, P.2
-
27
-
-
0029952518
-
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial inner membranes
-
Rapoport, T.A., Jungnickel, B., and Kutay, U. (1996). Protein translocation across the eukaryotic endoplasmic reticulum and bacterial inner membranes. Annu. Rev. Biochem. 65, 271-303.
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 271-303
-
-
Rapoport, T.A.1
Jungnickel, B.2
Kutay, U.3
-
28
-
-
0028486023
-
A single purification procedure for the major resident proteins of the ER lumen: Endoplasmin, BiP, calreticulin, and protein disulphide isomerase
-
Rowling, P.J.E., McLaughlin, S.H., Pollock, G.S., and Freedman, R.B. (1994). A single purification procedure for the major resident proteins of the ER lumen: endoplasmin, BiP, calreticulin, and protein disulphide isomerase. Protein Expression Purif. 5, 331-336.
-
(1994)
Protein Expression Purif.
, vol.5
, pp. 331-336
-
-
Rowling, P.J.E.1
McLaughlin, S.H.2
Pollock, G.S.3
Freedman, R.B.4
-
29
-
-
0026589260
-
Sec61p and BiP directly facilitate polypeptide translocation into the ER
-
Sanders, S.L., Whitfield, K.M., Vogel, J.P., Rose, M.D., and Schekman, R.W. (1992). Sec61p and BiP directly facilitate polypeptide translocation into the ER. Cell 69, 353-365.
-
(1992)
Cell
, vol.69
, pp. 353-365
-
-
Sanders, S.L.1
Whitfield, K.M.2
Vogel, J.P.3
Rose, M.D.4
Schekman, R.W.5
-
30
-
-
0025854858
-
A protein-conducting channel in the endoplasmic reticulum
-
Simon, S.M., and Blobel, G. (1991). A protein-conducting channel in the endoplasmic reticulum. Cell 65, 371-380.
-
(1991)
Cell
, vol.65
, pp. 371-380
-
-
Simon, S.M.1
Blobel, G.2
-
31
-
-
0029042422
-
BiP/Kar2p serves as a molecular chaperone during carboxypeptidase Y folding in yeast
-
Simons, J.F., Ferro-Novick, S., Rose, M.D., and Helenius, A. (1995). BiP/Kar2p serves as a molecular chaperone during carboxypeptidase Y folding in yeast. J. Cell Biol. 130, 41-49.
-
(1995)
J. Cell Biol.
, vol.130
, pp. 41-49
-
-
Simons, J.F.1
Ferro-Novick, S.2
Rose, M.D.3
Helenius, A.4
-
32
-
-
0025339295
-
Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast
-
Vogel, J., Misra, L.M., and Rose, M.D. (1990). Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast. J. Cell Biol. 110, 1885-1895.
-
(1990)
J. Cell Biol.
, vol.110
, pp. 1885-1895
-
-
Vogel, J.1
Misra, L.M.2
Rose, M.D.3
-
33
-
-
0028832266
-
Characterization of thenucleotide binding properties and ATPase activity of recombinant hamster BiP purified from bacteria
-
Wei, J., and Hendershot, L.M. (1995). Characterization of thenucleotide binding properties and ATPase activity of recombinant hamster BiP purified from bacteria. J. Biol. Chem. 270, 26670-26676.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26670-26676
-
-
Wei, J.1
Hendershot, L.M.2
|