BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer

Molecular and Cellular Biology

Volumn 27, Issue 5, 2007, Pages 1716-1729

  Kondo, Shinichi ^a   Saito, Atsushi ^a,b   Hino, Shin Ichiro ^a   Murakami, Tomohiko ^a,b   Ogata, Maiko ^a,b   Kanemoto, Soshi ^a,b   Nara, Satoshi ^a   Yamashita, Akinori ^b   Yoshinaga, Kazuya ^a   Hara, Hideaki ^c   Imaizumi, Kazunori ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^c GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; PROTEIN IRE1; PROTEIN KINASE; PROTEIN OASIS; PROTEIN PERK; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BBF2H7; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL NUCLEUS; CHROMOSOME 7; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; RAT; RNA TRANSLATION; SIGNAL TRANSDUCTION;

ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BRAIN ISCHEMIA; CELL LINE; CELL LINE, TUMOR; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOPLASMIC RETICULUM; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENES, REPORTER; GLIOMA; HELA CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LUCIFERASES; MALE; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; RATS; STRESS, MECHANICAL;

EID: 33847188475     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01552-06     Document Type: Article

References (37)

1. Adham, I. M., T. J. Eck, K. Mierau, N. Müller, M. A. Sallam, I. Paprotta, S. Schubert, S. Hoyer-Fender, and W. Engel. 2005. Reduction of spermatogenesis but not fertility in Creb314-deficient mice. Mol. Cell. Biol. 25:7657-7664.
2. Baird, S. D., M. Turcotte, R. G. Korneluk, and M. Holcik. 2006. Searching for IRES. RNA 12:1755-1785.
3. Bush, K. T., A. L. Goldberg, and S. K. Nigam. 1997. Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance. J. Biol. Chem. 272:9086-9092.
4. DeGracia, D. J., and H. L. Montie. 2004. Cerebral ischemia and the unfolded protein response. J. Neurochem. 91:1-8.
5. Den Boer, L. M., P. W. Hardy-Smith, M. R. Hogan, G. P. Cockram, T. E. Audas, and R. Lu. 2005. Luman is capable of binding and activating transcription from the unfolded protein response element. Biochem. Biophys. Res. Commun. 331:113-119.
6. Erickson, A. H., and G. Blobel. 1979. Early events in the biosynthesis of the lysosomal enzyme Cathepsin D. J. Biol. Chem. 254:11771-11774.
7. Hara, H., R. M. Friedlander, V. Gagliardini, C. Ayata, K. Fink, Z. Huang, M. Shimizu-Sasamata, J. Yuan, and M. A. Moskowitz. 1997. Inhibition of interleukin 1β converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage. Proc. Natl. Acad. Sci. USA 94:2007-2012.
8. Hara, H., P. L. Huang, N. Panahian, M. C. Fishman, and M. A. Moskowitz. 1996. Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion. J. Cereb. Blood Flow Metab. 16:605-611.
9. Harding, H. P., I. Novoa, Y. Zhang, H. Zeng, R. Wek, M. Schapira, and D. Ron. 2000. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell 6:1099-1108.
10. Harding, H. P., H. Zeng, Y. Zhang, R. Jungries, P. Chung, H. Plesken, D. D. Sabatini, and D. Ron. 2001. Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival. Mol. Cell 7:1153-1163.
11. Hossmann, K. A. 1994. Viability thresholds and the penumbra of focal ischemia. Ann. Neurol. 36:557-565.
12. Hu, B. R., S. Janelidze, M. D. Ginsberg, R. Busto, M. Perez-Pinzon, T. J. Sick, B. K. Siesjo, and C. L. Liu. 2001. Protein aggregation after focal brain ischemia and reperfusion. J. Cereb. Blood. Flow Metab. 21:865-875.
13. Imaizumi, K., M. Tsuda, Y. Imai, A. Wanaka, T. Takagi, and M. Tohyama. 1997. Molecular cloning of a novel polypeptide, DP5, induced during programmed neuronal death. J. Biol. Chem. 272:18842-18848.
14. Kaufman, R. J. 2002. Orchestrating the unfolded protein response in health and disease. J. Clin. Investig. 110:1389-1398.
15. Kondo, S., T. Murakami, K. Tatsumi, M. Ogata, S. Kanemoto, K. Otori, K. Iseki, A. Wanaka, and K. Imaizumi. 2005. OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes. Nat. Cell Biol. 7:186-194.
16. Koumenis, C., C. Naczki, M. Koritzinsky, S. Rastani, A. Diehl, N. Sonenberg, A. Koromilas, and B. G. Wouters. 2002. Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor elF2α. Mol. Cell. Biol. 22:7405-7416.
17. Kuwabara, K., M. Matsumoto, J. Ikeda, O. Hori, S. Ogawa, Y. Maeda, K. Kitagawa, N. Imuta, T. Kinoshita, D. M. Stern, H. Yanagi, and T. Kamada. 1996. Purification and characterization of a novel stress protein, the 150-kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brain. J. Biol. Chem. 271:5025-5032.
18. Liang, G., T. E. Audas, Y. Li, G. P. Cockram, J. D. Dean, A. C. Martyn, K. Kokame, and R. Lu. 2006. Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element. Mol. Cell. Biol. 26:7999-8010.
19. Lu, P. D., H. P. Harding, and D. Ron. 2004. Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response. J. Cell Biol. 167:27-33.
20. Macejak, D. G., and P. Sarnow. 1991. Internal initiation of translation mediated by the 5′ leader of a cellular mRNA. Nature 353:90-94.
21. Mouw, G., J. L. Zechel, J. Gamboa, W. D. Lust, W. R. Selman, and R. A. Ratcheson. 2003. Activation of caspase-12, an endoplasmic reticulum resident caspase, after permanent focal ischemia in rat. Neuroreport 14:183-186.
22. Murakami, T., S. Kondo, M. Ogata, S. Kanemoto, A. Saito, A. Wanaka, and K. Imaizumi. 2006. Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress. J. Neurochem. 96:1090-1100.
23. Nagamori, I., N. Yabuta, T. Fujii, H. Tanaka, K. Yomogida, Y. Nishimune, and H. Nojima. 2005. Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway. Genes Cells 10:575-594.
24. Nagamori, I., K. Yomogida, M. Ikawa, M. Okabe, N. Yabuta, and H. Nojima. 2006. The testes-specific bZip type transcription factor Tisp40 plays a role in ER stress responses and chromatin packaging during spermiogenesis. Genes Cells 11:1161-1171.
25. Newman, J. R., and A. E. Keating. 2003. Comprehensive identification of human bZIP interactions with coiled-coil arrays. Science 300:2097-2101.
26. Omori, Y., J. Imai, M. Watanabe, T. Komatsu, Y. Suzuki, K. Kataoka, S. Watanabe, A. Tanigami, and S. Sugano. 2001. CREB-H: a novel mammalian transcription factor belonging to the CREB/ATF family and functioning via the box-B element with a liver-specific expression. Nucleic Acids Res. 29:2154-2162.
27. Raggo, C., N. Rapin, J. Stirling, P. Gobeil, E. Smith-Windsor, P. O'Hare, and V. Misra. 2002. Luman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysis. Mol. Cell. Biol. 22:5639-5649.
28. Ron, D. 2002. Translational control in the endoplasmic reticulum stress response. J. Clin. Investig. 110:1383-1388.
29. Stirling, J., and P. O'Hare. 2006. CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P. Mol. Biol. Cell 17:413-426.
30. Storlazzi, C. T., F. Mertens, A. Nascimento, M. Isaksson, J. Wejde, O. Brosjo, N. Mandahl, and I. Panagopoulos. 2003. Fusion of the FUS and BBF2H7 genes in low grade fibromyxoid sarcoma. Hum. Mol. Genet. 12:2349-2358.
31. Tajiri, S., S. Oyadomari, S. Yan, M. Morioka, T. Gotoh, J. I. Hamada, Y. Ushio, and M. Mori. 2004. Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP. Cell Death Differ. 11:403-415.
32. Tamatani, M., T. Matsuyama, A. Yamaguchi, N. Mitsuda, Y. Tsukamoto, M. Taniguchi, Y. H. Che, K. Ozawa, O. Hori, H. Nishimura, A. Yamashita, M. Okabe, H. Yanagi, D. M. Stern, S. Ogawa, and M. Tohyama. 2001. ORP150 protects against hypoxia/ischemia-induced neuronal death. Nat. Med. 7:317-323.
33. Thoma, C., G. Bergamini, B. Galy, P. Hundsdoerfer, and M. W. Hentze. 2004. Enhancement of IRES-mediated translation of the c-myc and BiP mRNAs by the poly(A) tail is independent of intact eIF4G and PABP. Mol. Cell 15:925-935.
34. Urano, F., X. Wang, A. Bertolotti, Y. Zhang, P. Chung, H. P. Harding, and D. Ron. 2000. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 287:664-666.
35. Warnakulasuriyarachchi, D., S. Cerquozzi, H. H. Cheung, and M. Holcik. 2004. Translational induction of the inhibitor of apoptosis protein HIAP2 during endoplasmic reticulum stress attenuates cell death and is mediated via an inducible internal ribosome entry site element. J. Biol. Chem. 279:17148-17157.
36. Ye, J., R. B. Rawson, R. Komuro, X. Chen, U. P. Dave, R. Prywes, M. S. Brown, and J. L. Goldstein. 2000. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol. Cell 6:1355-1364.
37. Zhang, K., X. Shen, J. Wu, K. Sakaki, T. Saunders, D. T. Rutkowski, S. H. Back, and R. J. Kaufman. 2006. Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Cell 124:587-599.