Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation

Nature Cell Biology

Volumn 11, Issue 10, 2009, Pages 1205-1211

  Murakami, Tomohiko ^a   Saito, Atsushi ^a   Hino, Shin Ichiro ^a   Kondo, Shinichi ^a   Kanemoto, Soshi ^a   Chihara, Kazuyasu ^a   Sekiya, Hiroshi ^a   Tsumagari, Kenji ^a   Ochiai, Kimiko ^a   Yoshinaga, Kazuya ^b   Saitoh, Masahiro ^c   Nishimura, Riko ^c   Yoneda, Toshiyuki ^c   Kou, Ikuyo ^d   Furuichi, Tatsuya ^d   Ikegawa, Shiro ^d   Ikawa, Masahito ^e   Okabe, Masaru ^e   Wanaka, Akio ^f   Imaizumi, Kazunori ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d RIKEN   (Japan)

^e OSAKA UNIVERSITY   (Japan)

^f NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR OASIS; BONE MORPHOGENETIC PROTEIN 2; BONE SIALOPROTEIN; COLLAGEN TYPE 1; MESSENGER RNA; OSTEOPONTIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOPENIA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; TRANSCRIPTION INITIATION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE I; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENDOPLASMIC RETICULUM; FEMALE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; OSTEOGENESIS; PROMOTER REGIONS, GENETIC; PROTEIN FOLDING; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EUKARYOTA; MUS;

EID: 70349652275     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1963     Document Type: Article

References (32)

1. Honma, Y. et al. Identification of a novel gene, OASIS, which encodes for a putative CREB/ATF family transcription factor in the long-term cultured astrocytes and gliotic tissue. Brain research 69, 93-103 (1999).
2. Kondo, S. et al. OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes. Nature Cell Biol. 7, 186-194 (2005).
3. Murakami, T. et al. Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress. J. Neurochem. 96, 1090-1100 (2006).
4. Saito, A., Hino, S., Murakami, T., Kondo, S. & Imaizumi, K. A novel ER stress transducer, OASIS, expressed in astrocytes. Antioxid. Redox Signal. 9, 563-571 (2007).
5. Antony, J. M. et al. The human endogenous retrovirus envelope glycoprotein, syncytin-1, regulates neuroinflammation and its receptor expression in multiple sclerosis: A role for endoplasmic reticulum chaperones in astrocytes. J. Immunol. 179, 1210-1224 (2007).
6. Nikaido, T. et al. Expression of the novel transcription factor OASIS, which belongs to the CREB/ATF family, in mouse embryo with special reference to bone development. Histochem. Cell Biol. 116, 141-148 (2001).
7. Mori, K. Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell 10, 451-454 (2000).
8. Ron, D. Translational control in the endoplasmic reticulum stress response. J. Clin. Invest. 110, 1383-1388 (2002).
9. Schroder, M. & Kaufman, R. J. ER stress and the unfolded protein response. Mut. Res. 569, 29-63 (2005).
10. Franz-Odendaal, T. A., Hall, B. K. & Witten, P. E. Buried alive: How osteoblasts become osteocytes. Dev. Dyn. 235, 176-190 (2006).
11. Komori, T. et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89, 755-764 (1997).
12. Otto, F. et al. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89, 765-771 (1997).
13. Nakashima, K. et al. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108, 17-29 (2002).
14. Karsenty, G. & Wagner, E. F. Reaching a genetic and molecular understanding of skeletal development. Dev. Cell. 2, 389-406 (2002).
15. Ishida, Y. et al. Type I collagen in Hsp47-null cells is aggregated in endoplasmic reticulum and deficient in N-propeptide processing and fibrillogenesis. Mol. Cell. Biol. 17, 2346-2355 (2006).
16. Morello, R. et al. CRTAP is required for prolyl 3- hydroxylation and mutations cause recessive osteogenesis imperfecta. Cell 127 291-304 (2006).
17. Cabral, W. A. et al. Prolyl 3-hydroxylase 1 deficiency causes a recessive metabolic bone disorder resembling lethal/severe osteogenesis imperfecta. Nature Genet. 39, 359-365 (2007).
18. Saito, A. et al. Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nature Cell Biol. 11, 1197-1204 (2009).
19. Yang, X. et al. ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell 117, 387-398 (2004).
20. Rossert, J., Eberspaecher, H., and de Crombrugghe, B. Separate cis-acting DNA elements of the mouse pro-alpha 1(I) collagen promoter direct expression of reporter genes to different type I collagen-producing cells in transgenic mice. J. Cell Biol. 129 1421-1432 (1995).
21. Rossert, J. A., Chen, S. S., Eberspaecher, H., Smith, C. N., and de Crombrugghe, B. Identification of a minimal sequence of the mouse pro-alpha 1(I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblasts. Proc. Natl Acad. Sci. USA 6, 1027-1031 (1996).
22. Yamamoto, K., Yoshida, H., Kokame, K., Kaufman, R. J. & Mori, K. Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II. J Biochem. 136, 343-350 (2004).
23. Yamaguchi, A., Komori, T. & Suda, T. Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1. Endocr. Rev. 21, 393-411 (2000).
24. Shaffer, A. L. et al. XBP1, Downstream of Blimp-1, Expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity 21, 81-93 (2004).
25. Liu, T. et al. BMP-2 promotes differentiation of osteoblasts and chondroblasts in Runx2-deficient cell lines. J. Cell. Physiol. 211, 728-735 (2007).
26. Zhang, K. et al. Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Cell 124 587-599 (2006).
27. Kondo, S. et al. BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer. Mol. Cell. Biol. 27, 1716-1729 (2007).
28. Nagamori, I. et al. The testes-specific bZip type transcription factor Tisp40 plays a role in ER stress responses and chromatin packaging during spermiogenesis. Genes Cells. 11, 1161-1171 (2006).
29. Ikeda, F. et al. Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. J. Clin. Invest. 114, 475-484 (2004).
30. Domenicucci, C. et al. Characterization of porcine osteonectin extracted from foetal calvariae. Biochem. J. 253, 139-151 (1988).
31. Fisher, L. W. et al., Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop. Scand. Suppl. 266, 61-65 (1995).
32. Xiao, G. et al. Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression. J. Biol. Chem. 280, 30689-30696 (2005).