Direct proteasome binding and subsequent degradation of unspliced XBP-1 prevent its intracellular aggregation

FEBS Letters

Volumn 584, Issue 1, 2010, Pages 67-73

  Navon, Ami ^a   Gatushkin, Ariel ^b   Zelcbuch, Lior ^a   Shteingart, Shimon ^b   Farago, Marganit ^c   Hadar, Rivka ^b   Tirosh, Boaz ^b  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c HEBREW UNIVERSITY   (Israel)

Author keywords

ER stress; In vitro degradation; Proteasome; Ubiquitin; Unfolded protein response; XBP 1

Indexed keywords

MESSENGER RNA; PROTEASOME; X BOX BINDING PROTEIN 1;

AGGRESOME; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRUCTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; RNA SPLICING;

AMINO ACID SEQUENCE; CELL LINE; DNA-BINDING PROTEINS; HUMANS; PROTEASOME ENDOPEPTIDASE COMPLEX; RNA SPLICING; TRANSCRIPTION FACTORS; UBIQUITINATION;

MAMMALIA;

EID: 71549130987     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.11.069     Document Type: Article

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