Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1α-mediated NF-κB activation and down-regulation of TRAF2 expression

Molecular and Cellular Biology

Volumn 26, Issue 8, 2006, Pages 3071-3084

  Hu, Ping ^a   Han, Zhang ^a   Couvillon, Anthony D ^a   Kaufman, Randal J ^b   Exton, John H ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CASPASE 8; DEATH RECEPTOR; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE RECEPTOR; PROTEIN IRE1; PROTEIN IRE1ALPHA; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STRESS;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CASPASE 8; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; DOWN-REGULATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; ENZYME ACTIVATION; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; I-KAPPA B PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KINETICS; L CELLS (CELL LINE); LUCIFERASES; LUNG NEOPLASMS; MALE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NF-KAPPA B; PRECIPITIN TESTS; PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; THAPSIGARGIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR-ALPHA; TUNICAMYCIN;

ANIMALIA;

EID: 33645815074     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.26.8.3071-3084.2006     Document Type: Article

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