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Volumn 28, Issue 12, 2009, Pages 1757-1768

Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak

Author keywords

Bak; Endoplasmic reticulum; ER to mitochondria apoptotic communication; Mitochondrial apoptosis

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BH3 PROTEIN; BIM PROTEIN; CALCIUM ION; CASPASE 3; CASPASE 9; CERAMIDE DERIVATIVE; CYCLOSPORIN A; CYTOCHROME C; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; HYDROGEN PEROXIDE; PROTEIN BAK; PROTEIN BAX; PROTEIN IRE1; PROTEIN IRE1 ALPHA; PUMA PROTEIN; SMALL INTERFERING RNA; STAUROSPORINE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BCL 2 LIKE PROTEIN 11; BCL-2-LIKE PROTEIN 11; CALCIUM; CYTOCHROME B5; ERN2 PROTEIN, MOUSE; MEMBRANE PROTEIN; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE; PUMA PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN;

EID: 67649547153     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2009.90     Document Type: Article
Times cited : (76)

References (37)
  • 1
    • 33847328289 scopus 로고    scopus 로고
    • The Bcl-2 apoptotic switch in cancer development and therapy
    • Adams JM, Cory S (2007) The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26: 1324-1337
    • (2007) Oncogene , vol.26 , pp. 1324-1337
    • Adams, J.M.1    Cory, S.2
  • 2
    • 37849006735 scopus 로고    scopus 로고
    • A high-throughput screening for mammalian cell death effectors identifies the mitochondrial phosphate carrier as a regulator of cytochrome c release
    • Alcalá S, Klee M, Fernandez J, Fleischer A, Pimentel-Muiños FX (2008) A high-throughput screening for mammalian cell death effectors identifies the mitochondrial phosphate carrier as a regulator of cytochrome c release. Oncogene 27: 44-54
    • (2008) Oncogene , vol.27 , pp. 44-54
    • Alcalá, S.1    Klee, M.2    Fernandez, J.3    Fleischer, A.4    Pimentel-Muiños, F.X.5
  • 4
    • 33746912767 scopus 로고    scopus 로고
    • The permeability transition pore complex in cancer cell death
    • Brenner C, Grimm S (2006) The permeability transition pore complex in cancer cell death. Oncogene 25: 4744-4756
    • (2006) Oncogene , vol.25 , pp. 4744-4756
    • Brenner, C.1    Grimm, S.2
  • 5
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: Critical control points
    • Danial NN, Korsmeyer SJ (2004) Cell death: critical control points. Cell 116: 205-219
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 6
    • 33748668261 scopus 로고    scopus 로고
    • Bcl- XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line
    • Fiebig AA, Zhu W, Hollerbach C, Leber B, Andrews DW (2006) Bcl- XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line. BMC Cancer 6: 213
    • (2006) BMC Cancer , vol.6 , pp. 213
    • Fiebig, A.A.1    Zhu, W.2    Hollerbach, C.3    Leber, B.4    Andrews, D.W.5
  • 7
    • 36849043546 scopus 로고    scopus 로고
    • Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1
    • Fujino G, Noguchi T, Matsuzawa A, Yamauchi S, Saitoh M, Takeda K, Ichijo H (2007) Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1. Mol Cell Biol 27: 8152-8163
    • (2007) Mol Cell Biol , vol.27 , pp. 8152-8163
    • Fujino, G.1    Noguchi, T.2    Matsuzawa, A.3    Yamauchi, S.4    Saitoh, M.5    Takeda, K.6    Ichijo, H.7
  • 8
    • 33750523442 scopus 로고    scopus 로고
    • Mitochondrial calcium signalling and cell death: Approaches for assessing the role of mitochondrial Ca2+ uptake in apoptosis
    • Hajnoczky G, Csordas G, Das S, Garcia-Perez C, Saotome M, Sinha Roy S, Yi M (2006) Mitochondrial calcium signalling and cell death: approaches for assessing the role of mitochondrial Ca2+ uptake in apoptosis. Cell Calcium 40: 553-560
    • (2006) Cell Calcium , vol.40 , pp. 553-560
    • Hajnoczky, G.1    Csordas, G.2    Das, S.3    Garcia-Perez, C.4    Saotome, M.5    Sinha Roy, S.6    Yi, M.7
  • 10
    • 43449132366 scopus 로고    scopus 로고
    • Multisite phosphorylation regulates Bim stability and apoptotic activity
    • Hubner A, Barrett T, Flavell RA, Davis RJ (2008) Multisite phosphorylation regulates Bim stability and apoptotic activity. Mol Cell 30: 415-425
    • (2008) Mol Cell , vol.30 , pp. 415-425
    • Hubner, A.1    Barrett, T.2    Flavell, R.A.3    Davis, R.J.4
  • 11
    • 0037421190 scopus 로고    scopus 로고
    • Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membrane
    • Kaufmann T, Schlipf S, Sanz J, Neubert K, Stein R, Borner C (2003) Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membrane. J Cell Biol 160: 53-64
    • (2003) J Cell Biol , vol.160 , pp. 53-64
    • Kaufmann, T.1    Schlipf, S.2    Sanz, J.3    Neubert, K.4    Stein, R.5    Borner, C.6
  • 12
    • 14744281338 scopus 로고    scopus 로고
    • Bcl-X(L) specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum
    • Klee M, Pimentel-Muiños FX (2005) Bcl-X(L) specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum. J Cell Biol 168: 723-734
    • (2005) J Cell Biol , vol.168 , pp. 723-734
    • Klee, M.1    Pimentel-Muiños, F.X.2
  • 13
    • 46349097952 scopus 로고    scopus 로고
    • Recent progress in elucidating the molecular mechanism of the mitochondrial permeability transition pore
    • Leung AW, Halestrap AP (2008) Recent progress in elucidating the molecular mechanism of the mitochondrial permeability transition pore. Biochim Biophys Acta 1777: 946-952
    • (2008) Biochim Biophys Acta , vol.1777 , pp. 946-952
    • Leung, A.W.1    Halestrap, A.P.2
  • 15
    • 21244462014 scopus 로고    scopus 로고
    • BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death
    • Mathai JP, Germain M, Shore GC (2005) BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. J Biol Chem 280: 23829-23836
    • (2005) J Biol Chem , vol.280 , pp. 23829-23836
    • Mathai, J.P.1    Germain, M.2    Shore, G.C.3
  • 16
    • 0037163133 scopus 로고    scopus 로고
    • Calcium and calpain as key mediators of apoptosis-like death induced by vitamin D compounds in breast cancer cells
    • Mathiasen IS, Sergeev IN, Bastholm L, Elling F, Norman AW, Jaattela M (2002) Calcium and calpain as key mediators of apoptosis-like death induced by vitamin D compounds in breast cancer cells. J Biol Chem 277: 30738-30745
    • (2002) J Biol Chem , vol.277 , pp. 30738-30745
    • Mathiasen, I.S.1    Sergeev, I.N.2    Bastholm, L.3    Elling, F.4    Norman, A.W.5    Jaattela, M.6
  • 17
    • 9644295726 scopus 로고    scopus 로고
    • Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stressinduced apoptosis
    • Morishima N, Nakanishi K, Tsuchiya K, Shibata T, Seiwa E (2004) Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stressinduced apoptosis. J Biol Chem 279: 50375-50381
    • (2004) J Biol Chem , vol.279 , pp. 50375-50381
    • Morishima, N.1    Nakanishi, K.2    Tsuchiya, K.3    Shibata, T.4    Seiwa, E.5
  • 18
    • 0037390872 scopus 로고    scopus 로고
    • Spike, a novel BH3-only protein, regulates apoptosis at the endoplasmic reticulum
    • Mund T, Gewies A, Schoenfeld N, Bauer MK, Grimm S (2003) Spike, a novel BH3-only protein, regulates apoptosis at the endoplasmic reticulum. FASEB J 17: 696-698
    • (2003) FASEB J , vol.17 , pp. 696-698
    • Mund, T.1    Gewies, A.2    Schoenfeld, N.3    Bauer, M.K.4    Grimm, S.5
  • 19
    • 0036606540 scopus 로고    scopus 로고
    • ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
    • Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K, Hori S, Kakizuka A, Ichijo H (2002) ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 16: 1345-1355
    • (2002) Genes Dev , vol.16 , pp. 1345-1355
    • Nishitoh, H.1    Matsuzawa, A.2    Tobiume, K.3    Saegusa, K.4    Takeda, K.5    Inoue, K.6    Hori, S.7    Kakizuka, A.8    Ichijo, H.9
  • 20
    • 0037088658 scopus 로고    scopus 로고
    • Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores
    • Nutt LK, Pataer A, Pahler J, Fang B, Roth J, McConkey DJ, Swisher SG (2002) Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores. J Biol Chem 277: 9219-9225
    • (2002) J Biol Chem , vol.277 , pp. 9219-9225
    • Nutt, L.K.1    Pataer, A.2    Pahler, J.3    Fang, B.4    Roth, J.5    McConkey, D.J.6    Swisher, S.G.7
  • 21
    • 10644234677 scopus 로고    scopus 로고
    • Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor
    • Palmer AE, Jin C, Reed JC, Tsien RY (2004) Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor. Proc Natl Acad Sci USA 101: 17404-17409
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 17404-17409
    • Palmer, A.E.1    Jin, C.2    Reed, J.C.3    Tsien, R.Y.4
  • 22
    • 0038420824 scopus 로고    scopus 로고
    • 2- Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1,4,5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels
    • Peppiatt CM, Collins TJ, Mackenzie L, Conway SJ, Holmes AB, Bootman MD, Berridge MJ, Seo JT, Roderick HL (2003) 2- Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1,4,5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels. Cell Calcium 34: 97-108
    • (2003) Cell Calcium , vol.34 , pp. 97-108
    • Peppiatt, C.M.1    Collins, T.J.2    Mackenzie, L.3    Conway, S.J.4    Holmes, A.B.5    Bootman, M.D.6    Berridge, M.J.7    Seo, J.T.8    Roderick, H.L.9
  • 23
    • 0141961772 scopus 로고    scopus 로고
    • Cytofluorometric quantitation of apoptosis-driven inner mitochondrial membrane permeabilization
    • Poncet D, Boya P, Metivier D, Zamzami N, Kroemer G (2003) Cytofluorometric quantitation of apoptosis-driven inner mitochondrial membrane permeabilization. Apoptosis 8: 521-530
    • (2003) Apoptosis , vol.8 , pp. 521-530
    • Poncet, D.1    Boya, P.2    Metivier, D.3    Zamzami, N.4    Kroemer, G.5
  • 25
    • 0036097786 scopus 로고    scopus 로고
    • Keeping killers on a tight leash: Transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
    • Puthalakath H, Strasser A (2002) Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ 9: 505-512
    • (2002) Cell Death Differ , vol.9 , pp. 505-512
    • Puthalakath, H.1    Strasser, A.2
  • 26
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • Ron D, Walter P (2007) Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8: 519-529
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 27
    • 42549144606 scopus 로고    scopus 로고
    • Bcl-2 protein family members: Versatile regulators of calcium signaling in cell survival and apoptosis
    • Rong Y, Distelhorst CW (2008) Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosis. Annu Rev Physiol 70: 73-91
    • (2008) Annu Rev Physiol , vol.70 , pp. 73-91
    • Rong, Y.1    Distelhorst, C.W.2
  • 29
    • 33750200771 scopus 로고    scopus 로고
    • Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathways
    • Shibue T, Suzuki S, Okamoto H, Yoshida H, Ohba Y, Takaoka A, Taniguchi T (2006) Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathways. EMBO J 25: 4952-4962
    • (2006) EMBO J , vol.25 , pp. 4952-4962
    • Shibue, T.1    Suzuki, S.2    Okamoto, H.3    Yoshida, H.4    Ohba, Y.5    Takaoka, A.6    Taniguchi, T.7
  • 30
    • 33748789479 scopus 로고    scopus 로고
    • Mediators of endoplasmic reticulum stress-induced apoptosis
    • Szegezdi E, Logue SE, Gorman AM, Samali A (2006) Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 7: 880-885
    • (2006) EMBO Rep , vol.7 , pp. 880-885
    • Szegezdi, E.1    Logue, S.E.2    Gorman, A.M.3    Samali, A.4
  • 33
    • 26444593029 scopus 로고    scopus 로고
    • Mitochondria and endoplasmic reticulum: The lethal interorganelle cross-talk
    • Walter L, Hajnoczky G (2005) Mitochondria and endoplasmic reticulum: the lethal interorganelle cross-talk. J Bioenerg Biomembr 37: 191-206
    • (2005) J Bioenerg Biomembr , vol.37 , pp. 191-206
    • Walter, L.1    Hajnoczky, G.2
  • 35
    • 0036830438 scopus 로고    scopus 로고
    • Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL
    • Yamaguchi H, Wang HG (2002) Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL. J Biol Chem 277: 41604-41612
    • (2002) J Biol Chem , vol.277 , pp. 41604-41612
    • Yamaguchi, H.1    Wang, H.G.2
  • 37
    • 0035876483 scopus 로고    scopus 로고
    • BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
    • Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB (2001) BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 15: 1481-1486
    • (2001) Genes Dev , vol.15 , pp. 1481-1486
    • Zong, W.X.1    Lindsten, T.2    Ross, A.J.3    MacGregor, G.R.4    Thompson, C.B.5


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