Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury

Brain Research

Volumn 1370, Issue , 2011, Pages 227-237

  Krajewska, Maryla ^a   Xu, Lucy ^a   Xu, Wenjie ^a   Krajewski, Stan ^a   Kress, Christina L ^a   Cui, Jiankun ^a   Yang, Li ^a   Irie, Fumitoshi ^a   Yamaguchi, Yu ^a   Lipton, Stuart A ^a   Reed, John C ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

Brain injury; Neuroprotection; Unfolded protein response

Indexed keywords

BAX INHIBITOR 1; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN SIZE; BRAIN TISSUE; CELL COUNT; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FEMALE; HISTOPATHOLOGY; MOTOR PERFORMANCE; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; STROKE; TRAUMATIC BRAIN INJURY; UNFOLDED PROTEIN RESPONSE;

ANIMALS; BRAIN INJURIES; CELLS, CULTURED; CYTOPROTECTION; ENDOPLASMIC RETICULUM; HUMANS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; STROKE; UNFOLDED PROTEIN RESPONSE;

MUS; MUS MUSCULUS;

EID: 78651364538     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.11.015     Document Type: Article

References (49)

1. B. Ahlemeyer, and E. Baumgart-Vogt Optimized protocols for the simultaneous preparation of primary neuronal cultures of the neocortex, hippocampus and cerebellum from individual newborn (P0.5) C57Bl/6J mice J. Neurosci. Meth. 149 2005 110 120
2. B. Bailly-Maitre, C. Fondevila, F. Kaldas, N. Droin, F. Luciano, J.E. Ricci, R. Croxton, M. Krajewska, J.M. Zapata, J.W. Kupiec-Weglinski, D. Farmer, and J.C. Reed Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury Proc. Natl Acad. Sci. USA 103 2006 2809 2814
3. B. Bailly-Maitre, B.F. Belgardt, S.D. Jordan, B. Coornaert, M.J. von Freyend, A. Kleinridders, J. Mauer, M. Cuddy, C.L. Kress, D. Willmes, M. Essig, B. Hampel, U. Protzer, J.C. Reed, and J.C. Bruning Hepatic Bax inhibitor-1 inhibits IRE1alpha and protects from obesity-associated insulin resistance and glucose intolerance J. Biol. Chem. 285 2010 6198 6207
4. D. Bermpohl, Z. You, S.J. Korsmeyer, M.A. Moskowitz, and M.J. Whalen Traumatic brain injury in mice deficient in Bid: effects on histopathology and functional outcome J. Cereb. Blood Flow Metab. 26 2006 625 633
5. J.D. Blais, V. Filipenko, M. Bi, H.P. Harding, D. Ron, C. Koumenis, B.G. Wouters, and J.C. Bell Activating transcription factor 4 is translationally regulated by hypoxic stress Mol. Cell. Biol. 24 2004 7469 7482
6. D.E. Bredesen, R.V. Rao, and P. Mehlen Cell death in the nervous system Nature 443 2006 796 802
7. H.-J. Chae, N. Ke, S. Chen, H.-R. Kim, A. Godzik, M. Dickman, and J.C. Reed Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 (BI-1) homologs from animals, plants, and yeast Gene 323 2003 101 113
8. H.J. Chae, H.R. Kim, C. Xu, B. Bailly-Maitre, M. Krajewska, S. Krajewski, S. Banares, J. Cui, M. Digicaylioglu, N. Ke, S. Kitada, E. Monosov, M. Thomas, C.L. Kress, J.R. Babendure, R.Y. Tsien, S.A. Lipton, and J.C. Reed BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress Mol. Cell 15 2004 355 366
9. A.R. Frand, J.W. Cuozzo, and C.A. Kaiser Pathways for protein disulphide bond formation Trends Cell Biol. 10 2000 203 210
10. T. Gotoh, and M. Mori Nitric oxide and endoplasmic reticulum stress Arterioscler. Thromb. Vasc. Biol. 26 2006 1439 1446
11. H. Habelhah, S. Takahashi, S.G. Cho, T. Kadoya, T. Watanabe, and Z. Ronai Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB EMBO J. 23 2004 322 332
12. E.D. Hall, P.A. Yonkers, J.M. McCall, and J.M. Braughler Effects of the 21-aminosteroid U74006F on experimental head injury in mice J. Neurosurg. 68 1988 456 461
13. C. Hetz, P. Bernasconi, J. Fisher, A.H. Lee, M.C. Bassik, B. Antonsson, G.S. Brandt, N.N. Iwakoshi, A. Schinzel, L.H. Glimcher, and S.J. Korsmeyer Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha Science 312 2006 572 576
14. C. Iadecola, F. Zhang, R. Casey, M. Nagayama, and M.E. Ross Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene J. Neurosci. 17 1997 9157 9164
15. K. Kadoya, J. Fukushi, Y. Matsumoto, Y. Yamaguchi, and W.B. Stallcup NG2 proteoglycan expression in mouse skin: altered postnatal skin development in the NG2 null mouse J. Histochem. Cytochem. 56 3 2008 295 303
16. K.W. Kang, S.J. Lee, and S.G. Kim Molecular mechanism of nrf2 activation by oxidative stress Antioxid. Redox Signal. 7 2005 1664 1673
17. P. Kermer, M.H. Digicaylioglu, M. Kaul, J.M. Zapata, M. Krajewska, F. Stenner-Liewen, S. Takayama, S. Krajewski, S.A. Lipton, and J.C. Reed BAG1 over-expression in brain protects against stroke Brain Pathol. 13 2003 495 506
18. I. Kim, W. Xu, and J.C. Reed Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities Nat. Rev. Drug Discov. 7 2008 1013 1030
19. M. Krajewska, L.H. Smith, J. Rong, X. Huang, M.L. Hyer, N. Zeps, B. Iacopetta, S.P. Linke, A.H. Olson, J.C. Reed, and S. Krajewski Image analysis algorithms for immunohistochemical assessment of cell death events and fibrosis in tissue sections J. Histochem. Cytochem. 57 2009 649 663
20. G.H. Lee, H.K. Kim, S.W. Chae, D.S. Kim, K.C. Ha, M. Cuddy, C. Kress, J.C. Reed, H.R. Kim, and H.J. Chae Bax inhibitor-1 regulates endoplasmic reticulum stress-associated reactive oxygen species and heme oxygenase-1 expression J. Biol. Chem. 282 2007 21618 21628
21. K. Lei, and R.J. Davis JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis Proc. Natl Acad. Sci. USA 100 2003 2432 2437
22. F. Lisbona, D. Rojas-Rivera, P. Thielen, S. Zamorano, D. Todd, F. Martinon, A. Glavic, C. Kress, J.H. Lin, P. Walter, J.C. Reed, L.H. Glimcher, and C. Hetz BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha Mol. Cell 33 2009 679 691
23. K.D. McCullough, J.L. Martindale, L.O. Klotz, T.Y. Aw, and N.J. Holbrook Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state Mol. Cell. Biol. 21 2001 1249 1259
24. N. Nakanishi, S. Tu, Y. Shin, J. Cui, T. Kurokawa, D. Zhang, H.S. Chen, G. Tong, and S.A. Lipton Neuroprotection by the NR3A subunit of the NMDA receptor J. Neurosci. 29 2009 5260 5265
25. H. Nishitoh, A. Matsuzawa, K. Tobiume, K. Saegusa, K. Takeda, K. Inoue, S. Hori, A. Kakizuka, and H. Ichijo ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats Genes Dev. 16 2002 1345 1355
26. S. Oyadomari, and M. Mori Roles of CHOP/GADD153 in endoplasmic reticulum stress Cell Death Differ. 11 2004 381 389
27. A. Paxinos, J. Walton, A. Tzannes, M. Callanan, K. Hayes, and G.A. Murrell Advances in the management of traumatic anterior and atraumatic multidirectional shoulder instability Sports Med. 31 2001 819 828
28. G.V. Putcha, S. Le, S. Frank, C.G. Besirli, K. Clark, B. Chu, S. Alix, R.J. Youle, A. LaMarche, A.C. Maroney, and E.M. Johnson Jr. JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis Neuron 38 2003 899 914
29. H. Puthalakath, L. O'Reilly, P. Gunn, L. Lee, P. Kelly, N. Huntington, P. Hughes, E. Michalak, J.L. McKimm-Breschkin, N. Motoyama, T. Gotoh, S. Akira, P. Bouillet, and A. Strasser ER stress triggers apoptosis by activating BH3-only protein Bim Cell 129 2007 1337 1349
30. R.V. Rao, and D.E. Bredesen Misfolded proteins, endoplasmic reticulum stress and neurodegeneration Curr. Opin. Cell Biol. 16 2004 653 662
31. D. Ron, and P. Walter Signal integration in the endoplasmic reticulum unfolded protein response Nat. Rev. Mol. Cell Biol. 8 2007 519 529
32. Y.P. Rong, A.S. Aromolaran, G. Bultynck, F. Zhong, X. Li, K. McColl, S. Matsuyama, S. Herlitze, H.L. Roderick, M.D. Bootman, G.A. Mignery, J.B. Parys, H. De Smedt, and C.W. Distelhorst Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals Mol. Cell 31 2008 255 265
33. G.D. Rosen, and J.D. Harry Brain volume estimation from serial section measurements: a comparison of methodologies J. Neurosci. Meth. 35 1990 115 124
34. A.C. Ruifrok, and D.A. Johnston Quantification of histochemical staining by color deconvolution Anal. Quant. Cytol. Histol. 23 2001 291 299
35. M. Schroder, and R.J. Kaufman ER stress and the unfolded protein response Mutat. Res. 569 2005 29 63
36. X. Shen, K. Zhang, and R.J. Kaufman The unfolded protein response-a stress signaling pathway of the endoplasmic reticulum J. Chem. Neuroanat. 28 2004 79 92 (Pubitemid 39195253)
37. R.K. Srivastava, A.R. Srivastava, S.J. Korsmeyer, M. Nesterova, Y.S. Cho-Chung, and D.L. Longo Involvement of microtubules in the regulation of Bcl-2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase Mol. Cell. Biol. 18 1998 3509 3517
38. R.A. Swanson, M.T. Morton, G. Tsao-Wu, R.A. Savalos, C. Davidson, and F.R. Sharp A semiautomated method for measuring brain infarct volume J. Cereb. Blood Flow Metab. 10 1990 290 293
39. S. Tajiri, S. Oyadomari, S. Yano, M. Morioka, T. Gotoh, J.I. Hamada, Y. Ushio, and M. Mori Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP Cell Death Differ. 11 2004 403 415
40. T. Uehara, T. Nakamura, D. Yao, Z.Q. Shi, Z. Gu, Y. Ma, E. Masliah, Y. Nomura, and S.A. Lipton S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration Nature 441 2006 513 517
41. X.Z. Wang, and D. Ron Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase Science 272 1996 1347 1349
42. Y. Wei, S. Sinha, and B. Levine Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation Autophagy 4 2008 949 951
43. B.C. Westphalen, J. Wessig, F. Leypoldt, S. Arnold, and A. Methner BI-1 protects cells from oxygen glucose deprivation by reducing the calcium content of the endoplasmic reticulum Cell Death Differ. 12 2005 304 306
44. C. Xu, B. Bailly-Maitre, and J.C. Reed Endoplamic reticulum stress: cell life and death decisions J. Clin. Invest. 115 2005 2656 2664
45. C. Xu, W. Xu, A.E. Palmer, and J.C. Reed BI-1 regulates endoplasmic reticulum Ca2+ homeostasis downstream of Bcl-2 family proteins J. Biol. Chem. 283 2008 11477 11484
46. Q. Xu, and J.C. Reed BAX inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast Mol. Cell 1 1998 337 346
47. Xu Q., Ke N., Matsuyama S., and Reed J.C. Assays for studying bax-induced lethality in the yeast Saccharomyces cerevisiae Reed J.C. Methods in Enzymology. Apoptosis Vol. 322 2000 Academic Press San Diego 283 296
48. Z. You, S.I. Savitz, J. Yang, A. Degterev, J. Yuan, G.D. Cuny, M.A. Moskowitz, and M.J. Whalen Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice J. Cereb. Blood Flow Metab. 28 2008 1564 1573
49. W. Zou, P. Yue, F.R. Khuri, and S.Y. Sun Coupling of endoplasmic reticulum stress to CDDO-Me-induced up-regulation of death receptor 5 via a CHOP-dependent mechanism involving JNK activation Cancer Res. 68 2008 7484 7492